کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9189894 1579730 2005 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Recent advances in the treatment of tobacco dependence
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مغز و اعصاب بالینی
پیش نمایش صفحه اول مقاله
Recent advances in the treatment of tobacco dependence
چکیده انگلیسی
First, we examine the role of the endocannabinoid system (ECS) in the development of nicotine dependence and highlight the development of rimonabant, the first selective antagonist of the cannabinoid type 1 (CB-1) receptor. Second, we explore how heterogeneity among various subtypes of nicotinic receptors might be exploited to develop more specific agents acting at these receptors such as varenicline-a partial agonist at the α4β2 nicotinic receptor. Finally, we examine how selective inhibitors of monoamine oxidase (MAO) such as selegiline might be used as adjunctive medications for the treatment of tobacco dependence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neuroscience Research - Volume 5, Issues 2–4, November 2005, Pages 175-183
نویسندگان
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