کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9258885 1213575 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Changes of selected hematologic parameters during long-term immunoadsorption therapy
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Changes of selected hematologic parameters during long-term immunoadsorption therapy
چکیده انگلیسی
Changes of selected hematologic parameters were studied in six patients treated with immunoadsorption for myasthenia gravis. The mean duration of therapy was 18.6 months; 245 procedures were performed in total. Before and after each procedure the full blood count was examined. A decrease was noted in the hemoglobin concentration (median −7.27%) and in platelet count (median −5.63%) after each procedure. On the other hand, an increase in leukocyte count was noticed after each procedure (median 6.63%). However, in three patients, it was observed that with increasing numbers of procedures, the leukocyte count rises were lower during long-term treatment. We suppose that the decrease in hemoglobin concentration was induced both by the large volume of blood samples collected for laboratory testing and by the residual volume of blood which remains in the tubing. From the continuous decrease in leukocyte count after long-term treatment with immunoadsorption in our three patients, it may be concluded, that some type of immunomodulatory effect (immunosuppression) is involved.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transfusion and Apheresis Science - Volume 33, Issue 3, November 2005, Pages 299-304
نویسندگان
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