کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9275052 1592849 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The leukotoxin operon of Fusobacterium necrophorum is not present in other species of Fusobacterium
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
The leukotoxin operon of Fusobacterium necrophorum is not present in other species of Fusobacterium
چکیده انگلیسی
The complete nucleotide sequence of the leukotoxin operon of Fusobacterium necrophorum has been determined. The operon consists of three genes (lktBAC) of which the leukotoxin structural gene is the middle determinant. Southern and western blot analyses and flow cytometry analysis for biological activity of the culture supernatants were carried out to determine if the leukotoxin is present in other species of the genus Fusobacterium. Only the two subspecies of F. necrophorum were found to possess the leukotoxin locus and produce the toxin. The human periodontal pathogen, F. nucleatum does not produce detectable leukotoxin. The F. necrophorum leukotoxin was found to be active against human neutrophils.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Anaerobe - Volume 11, Issues 1–2, February–April 2005, Pages 123-129
نویسندگان
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