Photodynamic therapy in the management of malignant pleural mesothelioma: A review

Intra-operative (IOP) PDT in MPM is a safe procedure that requires more development and work regarding photosensitisers and light distribution systems for use in intra-pleural situations. The role of surgery in IOP-PDT appears to be cyto-reduction to ≤5 mm residual tumour thickness in order for PDT to be used effectively. Curative intent may depend on the stage of MPM and completeness of cyto-reduction with/without pulmonary resection.