Plasmablastic lymphoma of oral mucosa type: A case report

A case of the plasmablastic lymphoma of oral mucosa type is described. A 60-year-old white man presented an ulcerated and bleeding swelling in the upper lip. The right hard and soft palate showed a swelling covered by a yellowish membrane. Microscopical examination showed a monotonous diffuse lymphoid proliferation of large cells with plasmablastic differentiation. The cells were immunopositive for VS38c. A PCR demonstrated IgH with monoclonal pattern and EBV DNA. The lesions resolved after treatment with local radiotherapy and systemic chemotherapy. The patient remains free of the disease after twenty-three months of treatment.