کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
936610 1475169 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dopamine interferes with appetitive long-term memory formation in honey bees
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Dopamine interferes with appetitive long-term memory formation in honey bees
چکیده انگلیسی


• DA impairs appetitive long term memory consolidation in honey bees.
• DA antagonist improves appetitive memory.
• Results reveal a dopaminergic tonic modulation of appetitive memory.

Studies in vertebrates and invertebrates have proved the instructive role that different biogenic amines play in the neural representation of rewards and punishments during associative learning. Results from diverse arthropods and using different learning paradigms initially agreed that dopamine (DA) is needed for aversive learning and octopamine (OA) is needed for appetitive learning. However, the notion that both amines constitute separate pathways for appetitive and aversive learning is changing. Here, we asked whether DA, so far only involved in aversive memory formation in honey bees, does also modulate appetitive memory. Using the well characterized appetitive olfactory conditioning of the proboscis extension reflex (PER), we show that DA impairs appetitive memory consolidation. In addition, we found that blocking DA receptors enhances appetitive memory. These results are consistent with the view that aversive and appetitive components interact during learning and memory formation to ensure adaptive behavior.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Learning and Memory - Volume 106, November 2013, Pages 230–237
نویسندگان
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