کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9406494 | 1290125 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Strain-dependent regulation of plasticity-related proteins in the mouse hippocampus
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Strain-dependent regulation of plasticity-related proteins in the mouse hippocampus Strain-dependent regulation of plasticity-related proteins in the mouse hippocampus](/preview/png/9406494.png)
چکیده انگلیسی
A significant effect of strain was detected for total and phosphorylated calcium-calmodulin dependent kinase IIα (CaMKII, pCaMKII), phosphorylated mitogen-activated protein kinase (pMAPK), total and phosphorylated calcium-responsive element binding 1 (creb, pcreb), early-growth response protein 1 (egr 1), brain derived neurotrophic factor (BDNF), drebrin and postsynaptic density-95 (PSD-95). These results may indicate genetic determination of synaptic plasticity-related mechanisms relevant for the molecular events mediating hippocampal information processing and storage. Data presented herein highlight the importance of careful selection of the mouse strain for studies of synaptic plasticity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Behavioural Brain Research - Volume 165, Issue 2, 7 December 2005, Pages 240-246
Journal: Behavioural Brain Research - Volume 165, Issue 2, 7 December 2005, Pages 240-246
نویسندگان
Daniela D. Pollak, Theresa Scharl, Friedrich Leisch, Kurt Herkner, Santiago R. Villar, Harald Hoeger, Gert Lubec,