کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9471081 1320065 2005 28 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analytical solution of the cable equation with synaptic reversal potentials for passive neurons with tip-to-tip dendrodendritic coupling
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Analytical solution of the cable equation with synaptic reversal potentials for passive neurons with tip-to-tip dendrodendritic coupling
چکیده انگلیسی
A passive cable model is presented for a pair of electrotonically coupled neurons in order to investigate the effects of tip-to-tip dendrodendritic gap junctions on the interaction between excitation and either pre or postsynaptic inhibition. The model represents each dendritic tree by a tapered equivalent cylinder attached to an isopotential soma. Analytical solution of the cable equation with synaptic reversal potentials is considered for each neuron to yield a system of Volterra integral equations for the voltage. The solution to the system of linear integral equations (expressed as a Neumann series) is used to determine the current spread within the two coupled neurons, and to re-examine the sensitivity of the soma potentials (in particular) to the coupling resistance for various loci of synaptic inputs. The model is actually posed generally, so that active as well as passive properties could be considered. In the active case, a system of non-linear integral equations is derived for the voltage.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mathematical Biosciences - Volume 196, Issue 2, August 2005, Pages 125-152
نویسندگان
,