کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9573247 | 1388893 | 2005 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Phase synchronization and coherence resonance of stochastic calcium oscillations in coupled hepatocytes
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Phase synchronization and coherence resonance of stochastic calcium oscillations in coupled hepatocytes Phase synchronization and coherence resonance of stochastic calcium oscillations in coupled hepatocytes](/preview/png/9573247.png)
چکیده انگلیسی
The frequency of free cytosolic calcium concentration ([Ca2+]) oscillations elicited by a given agonist concentration differs between individual hepatocytes. However, in multicellular systems of rat hepatocytes and even in the intact liver, [Ca2+] oscillations are synchronized and highly coordinated. In this paper, we have investigated theoretically the effects of gap junction permeable to calcium and of the total Ca2+ channel number located on endoplasmic reticulum on intercellular synchronization. Figures of ratio between mean oscillating frequency of coupled cells describe visually the process of phase-locking. By virtue of a set of phase analysis, we can observe a gradual transition from synchronous behavior to nonsynchronous behavior. Furthermore, a signal-to-noise ratio in two dimensional parameter space (coupling strength-total Ca2+ channel number) has suggested that, coherence resonance will occur for appropriate noise and coupling.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biophysical Chemistry - Volume 115, Issue 1, 1 May 2005, Pages 37-47
Journal: Biophysical Chemistry - Volume 115, Issue 1, 1 May 2005, Pages 37-47
نویسندگان
Dan Wu, Ya Jia, Lijian Yang, Quan Liu, Xuan Zhan,