Dendronization of gold and CdSe/cdS (core-shell) quantum dots with tomalia type, thiol core, functionalized poly(amidoamine) (PAMAM) dendrons

Poly(amidoamine) (PAMAM) dendrimers containing disulfide cores (i.e., cystamine) and possessing carboxylic acid or hydroxyl terminal groups were reduced with dithiothreitol (DTT) to yield single site, thiol core, functionalized PAMAM dendron reagents. These thiol functionalized dendron reagents were used to surface modify (dendronize) both gold nanoparticles, as well as CdSe/CdS (core-shell) quantum dots (QDs). Dendronization involved self-assembly of the focal point thiol functional dendrons at the metal interface of both gold and CdSe/CdS QDs by ligand exchange of protective surfactants used for their synthesis. The synthesis, characterization and preliminary luminescence studies of these new dendritic hybrids are reported.