کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9667538 | 863757 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Shannon information and self-similarity in whole genomes
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The Shannon information (SI) in distributions of occurrence frequency of short words in whole genomes is shown to exhibit universality. For given word length, the SI in genomes of all lengths is the same as that in random sequences of a universal lengths Lr. For the shorter words Lr is far shorter than the genome. For example, Lrâ¼1000 bases for three-letter words. We further show that whole genomes are highly self-similar in the sense that any segment of the genome down to a length of Îsim, about twice Lr, also shares the universal property. We devise a simple genome growth model in which genome-size sequences grown by maximally stochastic segmental duplication and random mutation possess the universal and self-similar properties of genomes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computer Physics Communications - Volume 169, Issues 1â3, 1 July 2005, Pages 218-221
Journal: Computer Physics Communications - Volume 169, Issues 1â3, 1 July 2005, Pages 218-221
نویسندگان
Ta-Yuan Chen, Li-Ching Hsieh, Hoong-Chien Lee,