کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9723271 1475234 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat
چکیده انگلیسی
Adenosine A1 and A2A receptor agonists and antagonists have been reported to alter learning and memory. The aim of our study was to investigate the involvement of adenosinergic system in memory retrieval into posterior cingulate cortex (PCC) of Wistar rats. To clarify this question, we tested specifics agonist and antagonists of adenosine A1 and A2A receptors in rats submitted to a one-trial inhibitory avoidance task. The stimulation of adenosine A1 and A2A receptors by CPA and CGS21680, respectively, impaired memory retrieval for inhibitory avoidance task, into PCC. These findings provide behavioral evidence for the role of adenosinergic system in the memory retrieval into PCC.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Learning and Memory - Volume 83, Issue 3, May 2005, Pages 217-223
نویسندگان
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