Resolution of overlapping spectra by curve-fitting

In this paper we present a novel method of curve-fitting based on Gaussian function, which is used to resolve the overlapping peaks. Correctly choosing the minimum separable peak-peak interval (MSI) is crucial for this type of problem. We propose a method that chooses appropriate MSI by analyzing the curve-fitting error changes with the MSI. The resolution of several kinds of overlapping peaks with computer-simulated noise has been performed and discussed in details. This method has been used for resolving of the UV-vis overlapping spectrum. The results are satisfactory and clearly show the effectiveness of the proposed method.