کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9743881 | 1491201 | 2005 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Determination of acetone in breath
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Determination of acetone in breath Determination of acetone in breath](/preview/png/9743881.png)
چکیده انگلیسی
A light emitting diode (LED)-based photometric method for the measurement of gaseous acetone in human breath is presented. The detection chemistry is based on the reaction of acetone with alkaline salicylaldehyde to form a colored product, which absorbs in the blue and can be monitored with GaN-based LEDs with emission centered at 465Â nm. Gaseous acetone in breath is sampled with a porous membrane based diffusion scrubber (DS). The collected sample in the continuously flowing water carrier reacts with the reagent solution. We have used two approaches to collect breath acetone: the use of a face mask and a Mylar balloon as a collection bag. With the face mask approach, the expired air can be measured over long periods without major subject discomfort, balloon collection (5Â l) permits four measurements from a single fill. The LED-based liquid core waveguide (LCW) absorbance detector utilized sapphire ball lenses to prevent exposure of other optical components to a hot alkaline reagent solution. The high refractive index of the final mixture permitted the use of an inexpensive fluorinated ethylene copolymer (FEP Teflon®) tube as a 10Â cm long LCW. The limit of detection (S/NÂ =Â 3) is 14Â ppbv gaseous acetone, and the linear range extends to 1.21Â ppmv. The concentration range in 11 volunteer subjects ranged from 176 to 518Â ppbv.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 535, Issues 1â2, 11 April 2005, Pages 189-199
Journal: Analytica Chimica Acta - Volume 535, Issues 1â2, 11 April 2005, Pages 189-199
نویسندگان
Norio Teshima, Jianzhong Li, Kei Toda, Purnendu K. Dasgupta,