Thermodynamic approach to nano-properties of cell membrane

• Irreversibility is the fundamental quantity for the analysis of biosystems.
• The entropy generation describes irreversibility.
• Cell nanomechanics is useful in biological and medical use.
• A thermodynamic approach to cell nanomechanics is suggested.

Biomechanical analyses of DNA have pointed out the connections among forces, thermodynamics and kinetics. The entropy generation approach has been suggested as a thermodynamic approach to evaluate the accessible states for cancer systems, in relation to their specific thermodynamic quantities, including mechanical properties. In this paper, a theoretical approach for the thermodynamic evaluation of the nano-behaviour of the cell wall is suggested. The aim is to provide theoretical bases to the analysis of cells and their properties by applying the thermodynamic approach to irreversibility.