Nanogold synthesis by inert gas condensation for immuno-chemistry probes

Nanogold clusters synthesized through a chemical process involving 11 or 55 atoms of gold have been widely used for immuno-chemistry probes, in the form of nanoclusters conjugated with biomolecules. The creation of 1 nm size nanogold particles by a materials engineering process has been largely undeveloped. Therefore, the objective of this study is to minimize the size of gold nanoparticle by means of controlling the operating temperature and the chamber pressure during inert gas condensation processing. The size of the gold nanoparticles was resultant of the processing conditions such as the evaporation temperatures and chamber pressures. At a temperature of 1124 °C and pressure of 133 Pa, we were able to obtain approximately 1 nm size nanogold particles.