کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9885120 | 1537151 | 2005 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Involvement of gap junctional communication in secretion
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
Glands were the first type of tissues in which the permissive role of gap junctions in the cell-to-cell transfer of membrane-impermeant molecules was shown. During the 40 years that have followed this seminal finding, gap junctions have been documented in all types of multicellular secretory systems, whether of the exocrine, endocrine or pheromonal nature. Also, compelling evidence now indicates that gap junction-mediated coupling, and/or the connexin proteins per se, play significant regulatory roles in various aspects of gland functions, ranging from the biosynthesis, storage and release of a variety of secretory products, to the control of the growth and differentiation of secretory cells, and to the regulation of gland morphogenesis. This review summarizes this evidence in the light of recent reports.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - Biomembranes - Volume 1719, Issues 1â2, 20 December 2005, Pages 82-101
Journal: Biochimica et Biophysica Acta (BBA) - Biomembranes - Volume 1719, Issues 1â2, 20 December 2005, Pages 82-101
نویسندگان
Laetitia Michon, Rachel Nlend Nlend, Sabine Bavamian, Lorraine Bischoff, Nathalie Boucard, Dorothée Caille, José Cancela, Anne Charollais, Eric Charpantier, Philippe Klee, Manon Peyrou, Céline Populaire, Laurence Zulianello, Paolo Meda,