دانلود مقالات ISI درباره 4E-Bp1 + ترجمه فارسی

کرکومین در برابر کاردیومیوپاتی دیابتی، با ترویج سوختگی و کاهش آپوپتوز

Curcumin protects against diabetic cardiomyopathy by promoting autophagy and alleviating apoptosis

Keywords: Diabetic cardiomyopathy; Curcumin; Autophagy; Apoptosis; Beclin1; 3-MA; 3-methyladenine; 4E-BP1; 4E-binding protein 1; AMPK; 5′ adenosine monophosphate -activated protein kinase; BH; Bcl-2-homology; CC; AMPK inhibitor compound C; mTOR; mammalian target

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

مکانیسم اثرات دکوزینوالنول بر سیستم تولید مثل و ناهنجاری جنین: وضعیت فعلی و چالش های آینده

Mechanism of deoxynivalenol effects on the reproductive system and fetus malformation: Current status and future challenges

Keywords: 3β-HSD; 3β-hydroxysteroid dehydrogenase/isomer; 4E-BP1; 4E binding protein, eIF4E repressor protein; Col9A2; alpha 2 (IX) collagen; COCs; cumulus oocyte complexes; DHEA; dehydroepiandrosterone; DON (DNV); Deoxynivalenol; eIF-4E; eukaryotic initiation fa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

بوتیین در سلامت و بیماری: یک بررسی جامع

Butein in health and disease: A comprehensive review

Keywords: Butein; Rhus verniciflua; Chronic diseases; Prevention; Treatment; 4E-BP1; eIF4E binding protein 1; ACE; angiotensin converting enzyme; ACTA2; alpha-actin-2; AGEs; advanced glycation end products; ALDH1A3; aldehyde dehydrogenase 1 family member A3; ALL; a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

پروتئین 2 مانند گلوکاگون، انتروندوکریین، کنترل حرکت اسید آمینه اسید را کنترل می کند

Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport

Keywords: GLP-2; GLP-1; Amino acid absorption; Rapamycin; Gut peptides; mTORC1; mechanistic target of rapamycin complex 1; 4E-BP1; eukaryotic translation initiation factor 4E (eIF4e)-binding protein 1; GLP-1; Glucagon-like peptide-1; AA; amino acid; LC-MS/MS; liqui

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

متفورمین سرکوب کننده گلوکز باعث واکنش اتوفایی در سلول های اندوتلیومی میکرروکوزولی شده و باعث مرگ سلول می شود

Metformin represses glucose starvation induced autophagic response in microvascular endothelial cells and promotes cell death

Keywords: 2DG; 2-deoxyglucose; 3MA; 3-methyl adenine; 4E-BP1; Eukaryotic translation initiation factor 4E-binding protein 1; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AMPK; AMP activated protein kinase; ATF4; Activating transcription factor 4; Baf B1; B

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

کولین مانع از رشد بیش از اندازه جنین می شود و اسید چرب جیوه و متابولیسم گلوکز را در مدل موش های چاقی مادر طبیعی می کند

Choline prevents fetal overgrowth and normalizes placental fatty acid and glucose metabolism in a mouse model of maternal obesity

Keywords: Acox1; peroxisomal acyl-coenzyme A oxidase 1; AKT; protein kinase B; CD36; fatty acid translocase; CPT1B; carnitine palmitoyltransferase 1b; E; embryonic day; FATP; fatty acid transport protein; GDM; gestational diabetes mellitus; GLUT; glucose transporte

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

تجزیه و تحلیل نقش هدف سیگنالینگ رپامایسین در متابولیسم اسپینگولایپید

Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism

Keywords: AbA; Aureobasidin A; ABC; ATP-binding cassette; AMPK; AMP-activated protein kinase; ATG; Autophagy-related; ATP; Adenosine triphosphate; C1P; Ceramide-1-phosphate; CERS; Ceramide synthase; CK2; Casein kinase II; CLS; Chronological lifespan; CMA; Chaperone

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

بینش های اخیر در مورد مکانیزم های مولکولی و رویکردهای درمانی برای کاهکسی قلب

Recent insights on the molecular mechanisms and therapeutic approaches for cardiac cachexia

Keywords: 4E-BP1; Eukaryotic translation initiation factor 4E binding protein; ACE; Angiotensin-converting enzyme; ANP; Atrial natriuretic peptide; BMD; Bone mineral density; BMI; Body mass index; BNP; Brain natriuretic peptide; CC; Cardiac cachexia; CHF; Chronic h

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

آتروفی عضلانی اسکلتی ناشی از گلوکوکورتیکوئیدی

Glucocorticoid-induced skeletal muscle atrophy

Keywords: FOXO; forkhead box O; GC; glucocorticoids; MuRF-1; muscle RING-finger protein-1; mTOR; mammalian target of rapamycin; IGF-I; Insulin-like Growth Factor-I; eIF4E; eukaryotic translation initiation factor 4E; S6K1; ribosomal protein kinase 1; 4E-BP1; eukary

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

تنظیم سنتز پروتئین عضلانی و اثرات حالت های کاتابولیک

Regulation of muscle protein synthesis and the effects of catabolic states

Keywords: 4E-BP1; eIF4E binding protein 1; 5′-UTR; 5′-untranslated region; AMPK; AMP-activated protein kinase; eIF; eukaryotic initiation factor; GCN2; general-control nonderepressible; GEF; guanine nucleotide exchange factor; GSK-3; glycogen synthase kinase-3;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

عوامل و مکانیسم های عضله اسکلتی در بیماری مزمن انسدادی ریه

Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

Keywords: 4E-BP1; 4E-binding protein-1; AA; amino acid; ALS; autophagy-lysosomal system; AMPK; adenosine monophosphate-activated protein kinase; COPD; chronic obstructive pulmonary disease; CRP; C-reactive protein; ERK; extracellular signal regulated kinase; FFM; f

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

یک مدار و پایه بیوشیمیایی برای علائم اسکلروز توبول: از صرع به نقص عصبی شناختی

A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits

Keywords: CNS; central nervous system; CreERT2; inducible Cre; CSF; cerebral spinal fluid; EEG; electroencephalography; 4E-BP1; eIF4E-binding protein 1; E; embryonic day; fl; floxed; FCDs; focal cortical dysplasias; FMR1; FMRP gene; FMRP; fragile X mental retardati

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

سرکوب بیان ژن PTEN میزبان برای بقای Leishmania donovani در ليشمانيوز احشايی هند

Suppression of host PTEN gene expression for Leishmania donovani survival in Indian visceral leishmaniasis

Keywords: Visceral leishmaniasis; pten; egr1; 4e-bp1; mRNA expression; PI3K signaling

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Deciphering the pathways that protect from IL-13-mediated potentiation of oxidative stress-induced dopaminergic nerve cell death

Keywords: Parkinson's disease; mTOR; Jak; Akt; 4E-BP1; Oxidative stress; BSA; bovine serum albumin; CM-H2DCFDA; 5-(and-6)-chloromethyl-2′,7′-dichlorofluorescein diacetate; mTOR; mammalian target of rapamycin; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Apoptosis and pro-death autophagy induced by a spirostanol saponin isolated from Rohdea chinensis (Baker) N. Tanaka (synonym Tupistra chinensis Baker) on HL-60 cells

Keywords: Spirostanol saponin; Autophagy; Apoptosis; Rohdea chinensis; Human acute promyelocytic leukemia; Akt; protein kinase B; AMPK; adenosine 5′-monophosphate-activated protein kinase; Baf-A1; bafilomycin A1; FBS; fetal bovine serum; JC-1; 5,5´,6,6´-tetrach

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

ALA-PDT suppressed the cell growth by Akt-/Erk-mTOR-p70 s6k pathway in human SZ95 sebocytes in vitro

Keywords: ALA; 5-aminolevulinicacid; PDT; photodynamictherapy; mTOR; mammalian targetof rapamycin; p70; S6 K p70S6Kinase p70S6; 4E-BP1; eukaryotic translation initiation factor 4E-binding protein 1; IGF; insulin-likegrowthfactor; AMPK; AMP-activated protein kinase;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-tumor effect of AZD8055 against neuroblastoma cells in vitro and in vivo

Keywords: NB; Neuroblastoma; IGF; Insulin and insulin-like growth factors; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; p70S6K; p70 ribosomal protein S6 kinase; 4E-BP1; eukaryotic translat

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1α/VEGF pathway

Keywords: JPJD; Jianpi Jiedu decoction; CRC; colorectal cancer; TUNEL; Terminal deoxynucleotidyl transferase dUTP nick end labeling; IHC; immunohistochemistry; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; mTOR; mammalian target of rapamyc

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

High glucose up-regulates Semaphorin 3A expression via the mTOR signaling pathway in keratinocytes: A potential mechanism and therapeutic target for diabetic small fiber neuropathy

Keywords: Semaphorin 3A; Diabetic small fiber neuropathy; Keratinocyte; mTOR; 4E-BP1; Eukaryotic initiation factor 4E-binding protein 1; AD; atopic dermatitis; CPT; cold perception threshold; DPN; diabetic peripheral neuropathy; DRG; dorsal nerve root ganglia; FPG;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy

Keywords: Epilepsy; Rapamycin; Everolimus; Pharmacokinetics; Tolerability; Levetiracetam; AKT; protein kinase B; ASD; anti-seizure drug; 4E-BP1; initiation factor 4E binding protein; HPβCD; hydroxypropyl-ß-cyclodextrin; MTD; maximal tolerated dose; MES-T; maximal

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Aberrant regulation of the Akt signaling network by human cytomegalovirus allows for targeting of infected monocytes

Keywords: Cytomegalovirus; Monocytes; Small-molecule inhibitor; HCMV; human cytomegalovirus; h; hour; EGF; epidermal growth factor; EGFR; EGF receptor; αvβ3; alpha v beta 3 integrin; gB; glycoprotein B; gH; glycoprotein H; PI3K; phosphoinositide 3-kinase; PTEN; p

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

p21-activated kinase 4 regulates HIF-1α translation in cancer cells

Keywords: Pak4; HIF-1α; Hypoxia; Akt; mTOR; 4E-BP1; Pak; p21-activated kinase; HIF; hypoxia-inducible factor; PHD; prolyl hydroxylase domain-containing protein; FBS; fetal bovine serum; HRE; hypoxia response element; PGK-1; phosphoglycerate kinase-1; DFO; desferri

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

ArticlePIM2 regulates stemness through phosphorylation of 4E-BP1

Keywords: 4E-BP1; ESC; Phosphorylation; Pim2; Stemness;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation

Keywords: AMPK; AMP-activated protein kinase; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; BAF; Bafilomycin A1; BiP (GRP78); Binding immunoglobulin Protein (78 kDa glucose regulated protein); BZ; bortezomib; CHOP; C/EBP-Homolog

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by PI3K-AKT signaling in 3T3-L1 cells

Keywords: 4E-BP1; 4E-binding protein1; C/EBP; CCAAT/ enhancer binding proteins; EGCG; epigallocatechin-3-gallate; FAS; fatty acid synthase; FOXO1; forkhead box-O1; HFD; high fat diet; IGF; insulin-like growth factor; IR; insulin resistance; IRS1; insulin receptor s

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Protein profiling and angiogenic effect of hypoxia-cultured human umbilical cord blood-derived mesenchymal stem cells in hindlimb ischemia

Keywords: ABL; abelson murine leukemia viral oncogene homolog; BCL-XL; B-cell lymphoma-extra large; Cy; Cyanine; DAVID; Database for annotation visualization and integrated discovery; DNA-PK; DNA-activated protein kinase; 4E-BP1; eukaryotic initiation factor 4E-bin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

AdipoRon, an adiponectin receptor agonist, attenuates PDGF-induced VSMC proliferation through inhibition of mTOR signaling independent of AMPK: Implications toward suppression of neointimal hyperplasia

Keywords: VSMCs; vascular smooth muscle cells; PDGF; platelet-derived growth factor; AMPK; AMP-activated protein kinase; ACC; acetyl CoA carboxylase; mTOR; mammalian target of rapamycin; p70S6K; p70 ribosomal protein S6 kinase; S6; S6 ribosomal protein; 4E-BP1; euk

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia

Keywords: 4E-BP1; Eukaryotic initiation factor 4E (eIF4E)-binding protein 1; ABL1; Abelson murine leukemia viral oncogene homolog 1; ADAM; A desintegrin and metalloproteinase; ALL; Acute lymphoblastic leukemia; AML; Acute myeloid leukemia; ANK; Ankyrin repeats; APC

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

ALA-PDT suppressing the cell growth and reducing the lipogenesis in human SZ95 sebocytes by mTOR signaling pathway in vitro

Keywords: ALA; 5-aminolevulinic acid; PDT; photodynamic therapy; SREBP; sterol-regulatory element binding proteins; PPAR; peroxisome proliferator-activated receptor; mTOR; mammalian target of rapamycin; p70; S6 K p70S6 Kinase; 4E-BP1; eukaryotic translation initiat

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Up-regulation of the active form of small GTPase Rab13 promotes macroautophagy in vascular endothelial cells

Keywords: AMPK; AMP-activated protein kinase; AO; acridine orange; AVOs; acidic vesicular organelles; FGF-2; fibroblast growth factor 2; Grb2; growth factor receptor binding protein 2; Rab13; Ras-related protein in brain 13; HA; hemagglutinin; HRP; Horseradish pero

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes

Keywords: 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; AMPK; AMP-activated protein kinase; BSA; bovine serum albumin; ConA; concanavalin A; eEF2; eukaryotic elongation factor 2; eIF; eukaryotic initiation factor; ERK; extracellular-signal-regulated

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

SOX4 Promotes Proliferative Signals by Regulating Glycolysis through AKT Activation in Melanoma Cells

Keywords: AKT; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; GLUT1; glucose transporter type 1; HK2; hexokinase 2; LDHA; lactate dehydrogenase A; MITF; micropthalmia-associated transcripti

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Protein and exercise in the prevention of sarcopenia and aging

Keywords: Sarcopenia; Protein; Aerobic exercise; Resistance exercise; Aging; Supplement; 1-RM; 1 repetition maximum; 4E-BP1; eukaryotic initiation factor 4E-binding protein-1; aLM; appendicular lean mass; BIA; bioelectrical impedance analysis; CSA; cross-sectiona

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2017 سفارش ترجمه

Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease

Keywords: AD; Alzheimer's disease; AGC; protein kinase A/protein kinase G/protein kinase C; Akt; protein kinase B; ATG13; autophagy-related gene 13; Aβ; amyloid-beta; BDNF; brain-derived neurotrophic factor; CaMKII; Ca2+/calmodulin-dependent kinase II; cAMP; cyc

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Sulforaphane inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation by targeting mTOR/p70S6kinase signaling independent of Nrf2 activation

Keywords: Sulforaphane (PubChem CID: 5350); Dimethyl Sulfoxide (PubChem CID: 679); ARE; antioxidant response element; CREB; cAMP-response element-binding protein; DAB; diaminobenzidine; DMSO; dimethyl sulfoxide; 4E-BP1; eukaryotic translation initiation factor 4E-b

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه

Glucosamine induces REDD1 to suppress insulin action in retinal Müller cells

Keywords: F6P; fructose 6-phosphate; HBP; Hexosamine Biosynthetic Pathway; GlcN6P; glucosamine-6-phosphate; GFAT; glutamine-fructose-6-phosphate amidotransferase; UDP-GlcNAc; UDP-N-acetylglucosamine; O-GlcNAc; O-GlcNAcylation; GAM; Glucosamine; VEGF; vascular endot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma

Keywords: Q; quercetin; BL; Burkitt's lymphoma; BCR; B cell receptor; GC; Germinal Center; EBV; Epstein-Barr virus; PI3K; phosphatidylinositol-3-kinase; AKT; AKT or protein kinase B; mTOR; mammalian target of rapamycin; BEZ235; NVP-BEZ235; I-c-Myc; c-Myc inhibi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportThe antidepressant-like effect of alarin is related to TrkB-mTOR signaling and synaptic plasticity

Keywords: GALP; galanin-like peptide; mTOR; mammalian target of rapamycin; TrkB; tropomyosin-related kinase B; ERK; extracellular signal-regulated kinase; AKT; protein kinase B; p70S6K; ribosomal protein S6 kinase; 4E-BP1; eukaryotic initiation factor 4E binding pr

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells

Keywords: 4E-BP1; 4E binding protein; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; ATP; adenosine triphosphate; DEPTOR; DEP domain containing mTOR-interacting protein; CI; complexes I; CII; complex II; CIII; complex III; CIV; complex

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells

Keywords: Akt; protein kinase B; Atg; autophagy-related gene; ECM; extracellular matrix; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; eIF4E; eukaryotic translation initiation factor 4E; Hsc70; heat shock cognate protein 70; LC3B; microtubule-associate

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation

Keywords: 4E-BP1; eukaryotic initiation factor 4E binding protein 1; AMPK; AMP-activated protein kinase; Atg13; autophagy-related 13; FIP200; 200 kilodalton focal adhesion kinase family kinase-interacting protein; GAP; GTPase activator protein; GATOR; GAP activity

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

Parthenolide induces autophagy via the depletion of 4E-BP1

Keywords: PTL; parthenolide; eIF4E; eukaryotic initiation factor 4E; 4E-BP1; translation initiation factor eIF4E binding protein 1; AML; acute myeloid leukemia; ER; endoplasmic reticulum; ROS; reactive oxygen species; mTOR; mammalian target of rapamycin; MEF; mouse

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKβ

Keywords: 4E-BP1; eukaryotic translation initiation factor 4E-binding protein; BMDM; bone marrow-derived macrophage; CM; conditioned medium; DMEM; Dulbecco's modified essential medium; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Significance of 4E-binding protein 1 as a therapeutic target for invasive urothelial carcinoma of the bladder

Keywords: Invasive urothelial carcinoma of bladder; mTOR pathway; 4E-BP1; Ku-0063794;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathways

Keywords: mTOR; Rapamycin; Rb; TGF-β; eIF4E; 4E-BP1; eIF4E-binding protein-1; CDK; cyclin-dependent kinase; eIF4E; eukaryotic initiation factor 4E; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; S6K; S6 kinase; TGF-β; transforming growth factor-β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The PI3K/AKT/mTOR pathway as a therapeutic target in ovarian cancer

Keywords: CCC; clear cell carcinoma; SAC; serous adenocarcinoma; mTOR; mammalian target of rapamycin; mTORC; mTOR complex; S6K-1; ribosomal S6 kinase-1; 4E-BP1; elF4E binding protein 1; PI3K; phosphatidylinositol 3-kinase; cisplatin; cis-diaminodichloroplatinum; PT

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress

Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; ATF-6; activating transcription factor-6; CHOP; C/EBP homologous protein; Dnajb9; DnaJ (Hsp40) homolog, subfamily B, member 9; 4E-BP1; eIF4E-binding protein; EDEM1; ER degradation-enhancing

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: A tale of two complexes

Keywords: mTOR; mTORC1; mTORC2; S6K; 4E-BP1; GBM;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Requirement of the eukaryotic translation initiation factor 4F complex in hepatitis E virus replication

Keywords: Hepatitis E virus; Eukaryotic translation initiation factor 4F complex; eIF4E-binding protein 1; Ribavirin; IFN-α; HEV; hepatitis E virus; eIF4F; eukaryotic translation initiation factor 4F; eIF4A; eukaryotic initiation translation factor 4A; eIF4G; euka

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2015 سفارش ترجمه

Phosphorylation dynamics of eukaryotic initiation factor 4E binding protein 1 (4E-BP1) is discordant with its potential to interact with eukaryotic initiation factor 4E (eIF4E)

Keywords: 4E-BP1; mTOR; 4E; Rapamycin; S6 kinase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه