Keywords: CYP; cytochrome P; Dex; dexamethasone; 5-AZA; 5-azacytidine; PB; phenobarbital sodium;
مقالات ISI (ترجمه نشده)
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Keywords: Mesenchymal Stem Cells; 5-Azacytidine; Umbilical Cord Blood; Chorion; Myogenic differentiation;
Keywords: 5-AC; 5-Azacytidine; CTCL; cutaneous T-cell lymphoma; DNMT; DNA methyltransferase; EGCG; (â)-Epi-gallocatechin-3-gallate; HAT; histone acetylase; HDAC; histone deacetylase; HDM; histone demethylase; HKMT; SAM-dependent histone lysine methyltransferase;
Keywords: 5-azacytidine; MDS; Renal impairment; CKD;
Keywords: EC-SOD; extracellular-SOD; TPA; 12-O-tetradecanoylphorbol-13-acetate; CPTH2; cyclopentylidene-(4-(4â²-chlorophenyl)thiazol-2-yl)hydrazone; ROS; reactive oxygen species; AZA; 5-azacytidine; TSA; trichostatin A; PBMCs; peripheral blood mononuclear cells; G
Keywords: BDNF; brain derived neurotrophic factor; CAMKII; calmodulin-dependent protein kinase II; Ca2+; calcium; cAMP; cyclic adenosine monophosphate; CBS; cystathionine-β-synthase; CCI; chronic constriction injury; CFA; complete Freund's adjuvant; cGMP; cyclic
Research on epigenetic mechanism of SFRP2 in advanced chronic myeloid leukemia
Keywords: Chronic myeloid leukemia; SFRP2; Epigenetic; 5-Azacytidine; WNT1;
5-Azacytidine engages an IRE1α-EGFR-ERK1/2 signaling pathway that stabilizes the LDL receptor mRNA
Keywords: Low-density lipoprotein receptor (LDLR); Hepatocytes; 5-Azacytidine; mRNA stabilization; 3â²-UTR; AU-rich elements; IRE1α/EGFR;
Coordinate regulation by transcription factors and DNA methylation in the core promoter region of SIRT6 in bovine adipocytes
Keywords: SIRT6; Promoter; Transcriptional regulation; DNA methylation; Bovine; Adipocyte; qPCR; real-time quantitative; CEBPβ; CCAAT enhancer binding protein beta; PAX6; paired box 6; KLF2; Kruppel-like factor 2; CMYB; myb proto-oncogene protein; NRF1; nuclear re
The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities
Keywords: Schistosoma mansoni; Epigenetics; 5-Azacytidine; Fecundity; RNA-Seq; Protein synthesis; Stem cells;
Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic
Keywords: ALL; Acute lymphoblastic leukemia; AML; Acute myeloid leukemia; AUC; Area under the curve; AZA; 5-azacytidine; 5-aza-CdR; 2â²-deoxy-5-azacytidine; 5-aza-CR; 5-azacytidine; AZN; Azanucleosides; BED; Biologically effective dose; BSC; Best supportive care;
Use of 5-azacitidine for therapy-related myeloid neoplasms in patients with concomitant active neoplastic disease
Keywords: Therapy-related myeloid neoplasms; Therapy-related myelodysplastic syndromes; Therapy-related acute myeloid leukemia; Myeloid leukemias and dysplasias; 5-Azacytidine; Hypomethylating agents;
Minimal traumatic brain injury causes persistent changes in DNA methylation at BDNF gene promoters in rat amygdala: A possible role in anxiety-like behaviors
Keywords: 5-Azacytidine; Amygdala; Anxiety; Brain-derived neurotrophic factor; DNA methylation; Minimal traumatic brain injury;
The added value of type I interferons to cytotoxic treatments of cancer
Keywords: Ab; antibody; ATLL; adult T-cell leukemia/lymphoma; ATM; ataxia-telangiectasia mutated; Aza; 5-azacytidine; BAFF; B-cell activating factor; BM; bone marrow; cGAMP; cyclic GMP-AMP; cGAS; cyclic GMP-AMP synthase; CIC; cancer initiating cell; CRC; colorectal
Azacytidine and miR156 promote rooting in adult but not in juvenile Arabidopsis tissues
Keywords: AR; adventitious root; AzaC; 5-azacytidine; miR156; microRNA156; FS; flower stem; Adventitious root formation; Arabidopsis thaliana; Hypomethylation; Juvenile; miR156; Phase change;
Developmental ethanol exposure impairs locomotor movement in Japanese medaka (Oryzias latipes) larvae targeting epigenome
Keywords: Fetal alcohol spectrum disorder; Swimming behavior; Japanese medaka; Ethanol; 5-Azacytidine; Photomotor response;
Nicotinamide; antioxidative and DNA hypomethylation effects in plant cells
Keywords: Cell leakage; Citric acid cycle enzymes; DNA damage; DNA methylation; Nicotinic acid; Oxidative stress; PARP (poly(ADP-ribose) polymerase; EC 2.4.2.30); 5-Aza; 5-azacytidine; AAPH; 2,2â²-azobis(2-amidinopropane) dihydrochloride; 3-AB; 3-aminobenzamide; D
DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies
Keywords: DNMT; DNA methyltransferase; 5azadC; 5-aza-2â²-deoxycytidine; 5azaC; 5-azacytidine; SAM; S-adenosyl-l-methionine; SAH; S-adenosyl-l-homocysteine; DNMTi; DNMT inhibitors; HDACi; histone deacetylase inhibitors; CpGs; 5â²-CpG-3â² dinucleotides; CGis; CpG
DNA methyltransferase 1 may be a therapy target for attenuating diabetic nephropathy and podocyte injury
Keywords: 5-azacytidine; diabetic db/db mice; diabetic nephropathy; DNA methylation inhibitor; podocyte;
Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes
Keywords: 5-AZC; 5-azacytidine; 5-FU; 5-fluorouracil; AV; arterivirus; CBV3; coxsackievirus B3; CoV; coronavirus; EAV; equine arteritis virus; EM; electron microscopy; ExoN; exoribonuclease; FCoV; feline coronavirus; FMDV; foot and mouth disease virus; HCoV-229E; h
Genetic and epigenetic regulation on the transcription of GABRB2: Genotype-dependent hydroxymethylation and methylation alterations in schizophrenia
Keywords: Hypermethylation; RNA expression; SNP; 5hmC/5mC; 5-azacytidine; Valproic acid;
Counter regulation of ECRG4 gene expression by hypermethylation-dependent inhibition and the Sp1 transcription factor-dependent stimulation of the c2orf40 promoter
Keywords: Sp1 transcription factor; Hypermethylation; Promoter; Jurkat cells; RACE; C2orf40; chromosome 2 open reading frame number 40; ECRG4; Esophageal Cancer Related Gene-4; Sp1; specific protein-1; RACE; Rapid Amplification of cDNA Ends; ChIP; Chromatin immunop
Risk-Adapted Approach to HLA-Matched Sibling Hematopoietic Cell Allografting: Impact of Adjusting Conditioning Intensity and Integrating Post-Transplant Therapeutic Interventions
Keywords: 5-Azacytidine; Allogeneic stem cell transplantation; Dasatinib; Personalized conditioning; Sorafenib;
Modulation of DNA methylation machineries in Japanese rice fish (Oryzias latipes) embryogenesis by ethanol and 5-azacytidine
Keywords: DNA methylation; DNA methyl transferase; Methyl binding protein; Japanese rice fish embryogenesis; Ethanol; 5-Azacytidine
Synergistic reduction of HIV-1 infectivity by 5-azacytidine and inhibitors of ribonucleotide reductase
Keywords: Lethal mutagenesis; Error catastrophe; Viral mutagenesis; Retrovirus; 5-Azacytidine; Resveratrol; Drug synergy; HIV-1
Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage
Keywords: ACs; articular chondrocytes; H3K4me2; histone 3 lysine 4 dimethylation; OA; osteoarthritis; WT; wild-type; IHC; immunohistochemistry; HE; haematoxylin and eosin; qPCR; quantitative real-time RT-PCR; P1; first passage of cultured cells; MeDIP; methylated D
The R2R3-type MYB gene OsMYB91 has a function in coordinating plant growth and salt stress tolerance in rice
Keywords: ROS; reactive oxygen species; MDA; malondialdehyde; POD; peroxidase; CAT; catalase; ChIP; chromatin immunoprecipitation; PEG; polyethylene glycol; 5-Aza; 5-azacytidine; Abiotic stress; Epigenetic modifications; OsMYB91; Oryza sativa; Plant growth;
Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells
Keywords: LNCaP; lymph node carcinoma of the prostate; NaBu; sodium butyrate; NED; neuroendocrine differentiation; SAHA; suberoylanilide hydroxamic acid; 5׳-azaC; 5-azacytidine; NNC 55-0396 (PubChem CID: 11957578); Paclitaxel (PubChem CID: 36314); Sodium butyrate
Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells
Keywords: Cancer Stem Cells; Chemotherapy Drug Resistance; iPSCs; Tumor Progression; 5-aza; 5-azacytidine; 5-FU; 5-fluorourail; AFP; alpha-fetoprotein; AJCC; American Joint Committee on Cancer; ALB; albumin; ATOH8; atonal homolog 8; AP; alkaline phosphatase; ATRA;
Dysregulation of the TGFBI gene is involved in the oncogenic activity of the nonsense mutation of hepatitis B virus surface gene sW182*
Keywords: HBV; hepatitis B virus; TGFBI; transforming growth factor-β-induced; HCC; hepatocellular carcinoma; HBcAg; hepatitis B core antigen; GSEA; gene set enrichment analysis; qPCR; quantitative polymerase chain reaction; CREB; cyclic AMP-responsive element bin
Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2,5-dihydroxybenzoic acid
Keywords: RPE; retinal pigment epithelium; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; Bdh2; β-hydroxybutyrate dehydrogenase-2; 2,5-DHBA; 2,5-dihydroxybenzoic acid; AMD; age-related macular degeneration; pRPE; primary cu
DNA-methylation dependent regulation of embryo-specific 5S ribosomal DNA cluster transcription in adult tissues of sea urchin Paracentrotus lividus
Keywords: rRNA; ribosomal RNA; rDNA; ribosomal DNA; NTS; non-transcribed spacer; SSCP; single-strand conformation polymorphism; 5-AZA; 5-azacytidine; VGGE; voltage gradient gel electrophoresis; bp; base pair; CCM; cell culture medium; MCF; millipore-filtered coelom
TGFβ1 contributes to cardiomyogenic-like differentiation of human bone marrow mesenchymal stem cells
Keywords: Human bone marrow; Mesenchymal stem cells; Cardiac differentiation; Transforming growth factor β1; 5-Azacytidine;
5,6-Dihydro-5-aza-2â²-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors
Keywords: 5-AZC; 5-azacytidine; dFdC; 2â²,2â²-difluoro-2â²-deoxycytidine; dFdU; 2â²,2â²-difluoro-2â²-deoxyuridine; DMSO; dimethylsulfoxide; KP-1212; 5-aza-5,6,-dihydro-2â²-deoxycytidine; MOI; multiplicity of infection; NRTI; nucleoside reverse transcriptase
Transcriptomic profiling of Aspergillus flavus in response to 5-azacytidine
Keywords: Aspergillus flavus; Aflatoxin biosynthesis; 5-Azacytidine; Transcriptome; RNA sequencing;
5-Azacytidine induces early stage apoptosis and promotes in vitro maturation by changing chromosomal construction in murine oocytes
Keywords: Oocytes; Mouse; 5-Azacytidine; Decondensation; Early apoptosis; Maturation; In vitro; Hypomethylation
Islet allograft rejection in sensitized mice is refractory to control by combination therapy of immune-modulating agents
Keywords: 5-Azacytidine; IL-2/anti-IL-2 complex; Islet transplantation; Memory; Sensitization
Enhancer of Zeste Homolog 2 Silences MicroRNA-218 in Human Pancreatic Ductal Adenocarcinoma Cells by Inducing Formation of Heterochromatin
Keywords: Pancreatic Cancer; Gene Regulation; Epigenetic; Messenger RNA Processing; 3â²-UTR; 3â²-untranslated region; 5AZAC; 5-azacytidine; DNMT; DNA methyltransferase; DZnep; 3-deazaneplanocin A; EZH2; enhancer of zeste 2 homolog; H3K27me3; histone 3 lysine 27 t
Efficacy of hypomethylating agents in therapy-related myelodysplastic syndromes
Keywords: Decitabine; 5-Azacytidine; Therapy-related cancer; Leukemia
Effects of matrix metalloproteinase-1 on the myogenic differentiation of bone marrow-derived mesenchymal stem cells in vitro
Keywords: 5-Aza; 5-azacytidine; ARS; Alizarin red S; bHLH; basic helix-loop-helix; BMSCs; bone marrow-derived mesenchymal stem cells; CCK-8; cell counting kit-8; DMD; Duchenne muscular dystrophy; DMEM; Dulbecco's modified Eagle's medium; ECM; extracellular matr
CpG methylation recruits sequence specific transcription factors essential for tissue specific gene expression
Keywords: Epigenetics; DNA methylation; Transcription; CpG island; Cancer; 5-azacytidine
Chromatin-modifying agents in anti-cancer therapy
Keywords: Epigenetic inhibitors; HDAC; DNMT; Anti-cancer therapy; Clinical trials; Combinatory treatments; AML; acute myeloid leukemia; AZA; 5-azacytidine; CMA; chromatin-modifying agent; CML; chronic myeloid leukemia; CMML; chronic myelomonocytic leukemia; CTCL; c
Functional characterization of the human translocator protein (18Â kDa) gene promoter in human breast cancer cell lines
Keywords: HBC; human breast cancer; HMEC; human mammary epithelial cells; TSPO; translocator Protein (18Â kDa); ChIP; chromatin immunoprecipitation; TSA; Trichostatin A; AZA; 5-Azacytidine; Sp/KLF; Specificity Protein/Krüppel-like factor; TSPO; Breast cancer; Meta
DNA methylation-based biomarkers in serum of patients with breast cancer
Keywords: 5-Aza-CdR; 5-aza-2â²-deoxycytidine; 5-Aza-CR; 5-azacytidine; 5mC; 5-methylcytidine; AIMS; amplification of inter-methylated sites; APC; adenomatous polyposis coli; BiMP; bisulfite methylation profiling; BRCA1; breast cancer gene 1; BsPP; bisulfite padloc
5-Azacytidine as Salvage Treatment in Relapsed Myeloid Tumors after Allogeneic Bone Marrow Transplantation
Keywords: Acute myeloid leukemia; Donor lymphocyte infusion; 5-Azacytidine; Myelodysplastic syndrome; Graft-versus-host disease
DNA demethylation in PD-1 gene promoter induced by 5-azacytidine activates PD-1 expression on Molt-4 cells
Keywords: 5-Azacytidine; PD-1 gene promoter demethylation; PD-1 expression; Molt-4 cells
Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury
Keywords: Neuropathic pain; Chronic constriction injury; DNA methylation; 5-azacytidine; Methyl-CpG-binding protein 2
5-Azacytidine in myelodysplastic syndromes: A clinical practice guideline
Keywords: Myelodysplastic syndrome; Systematic review; Randomized trials; Hypomethylating agents; 5-Azacytidine; Vidaza
Differentiation induction of cardiac c-kit positive cells from rat heart into sinus node-like cells by 5-azacytidine
Keywords: Cardiac stem cells; Differentiation; 5-Azacytidine; Cardiac marker; Rat;
A novel, efficient method to derive bovine and mouse embryonic stem cells with in vivo differentiation potential by treatment with 5-azacytidine
Keywords: Methylation; 5-azacytidine; Epigenetic modification; Bovine; Murine; Teratoma