A 27-Year-Old Woman With Constipation: Diagnosis and Treatment
Keywords: FDA; Food and Drug Administration; 5-HT; serotonin; IBS; irritable bowel syndrome; PEG; polyethylene glycol;
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Intermittent hypoxia augments acute hypoxic sensing via HIF-mediated ROS
Keywords: NADPH oxidases; Mitochondrial electron transport chain; S-glutathionylation; T-type Ca2+ channels; Ryanodine receptors; Endothelin; 5-HT
A subpopulation of serotonin1B receptors colocalize with the AMPA receptor subunit GluR2 in the hippocampal dentate gyrus
Keywords: 5-HT; 5-hydroxytryptamine; 5-HT1BR; serotoinin1B receptor; 5-HT1BR-LI; 5-HT1BR-like immunoreactivity; AMPA; amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid; Ax; small unmyelinated axon; AxT; axon terminal; BSA; bovine serum albumin; Den; dendrite; DG;
Effect of chronic fluoxetine treatment on male and female rat erythrocyte and prefrontal cortex fatty acid composition
Keywords: 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; AA; arachidonic acid; cPLA2; cytosolic phospholipase A2; DHA; docosahexaenoic acid; FLX; fluoxetine; MDD; major depressive disorder; n-3; omega-3; NFLX; norfluoxetine; PFC; prefrontal cortex; PUFA; poly
A 5-HT1A-like receptor is involved in the regulation of the embryonic rotation of Lymnaea stagnalis L.
Keywords: Lymnaea; Embryo; 5-HT; Receptor;
The effect of mirtazapine add on therapy to risperidone in the treatment of schizophrenia: A double-blind randomized placebo-controlled trial
Keywords: 5-HT; Mirtazapine; Negative symptoms; Schizophrenia
Neurophysiological study on possible protective and therapeutic effects of Sidr (Zizyphus spina-christi L.) leaf extract in male albino rats treated with pentylenetetrazol
Keywords: Zizyphus; Pentylenetetrazol; NE; DA; 5-HT; Seizure
Blockade of androgen or estrogen receptors reduces nandrolone's ability to modulate acute reward-related neurochemical effects of amphetamine in rat brain
Keywords: Amphetamine; Anabolic–androgenic steroids; Androgen receptor; Dopamine; Estrogen receptor; Nucleus accumbens; 5-HT
Research ArticlePlatelet serotonin (5-HT) levels in interferon-treated patients with hepatitis C and its possible association with interferon-induced depression
Keywords: 5-HT; 5-hydroxytryptamine (serotonin); ANOVA; analysis of variance; ELISA; enzyme-linked immunosorbent assay; HADS; Hospital Anxiety and Depression Scale; HCV; hepatitis C virus; IVDU; intravenous drug usage; P; statistical probability; SPSS; Statistical
Serotonin regulates an acyl-CoA-binding protein (ACBP) gene expression in the midgut of Rhodnius prolixus
Keywords: ACBP; Lipid; Acyl-CoA ester; Serotonin; 5-HT; Rhodnius prolixus
Effects of dietary l-tryptophan on the agonistic behavior, growth and survival of juvenile mud crab Scylla serrata
Keywords: Juvenile mud crab; Agonistic behavior; Survival; Growth; Tryptophan; 5-HT
Effect of neonatal hypoxia on the development of intraspinal serotonergic fibers in relation to spinal motoneurons
Keywords: Hypoxia; 5-HT; Development; Spinal cord; Motoneuron;
Neural mechanism of electroacupuncture's hypotensive effects
Keywords: Hypertension; Arcuate nucleus; Ventrolateral periaqueduct gray; Rostral ventrolateral medulla; Glutamate; Endorphins; Enkephalin; GABA; 5-HT
Receptor-genes cross-talk: effect of chronic 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino) tetralin treatment on the expression of key genes in brain serotonin system and on behavior
Keywords: chronic 8-OH-DPAT treatment; 5-HT1A; 5-HT2A receptors; 5-HT transporter; tryptophan hydroxylase-2 genes expression; behaviorDOI, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane; rPol II, DNA-dependent RNA-polymarese II; TPH-2, tryptophan hydroxylase-2; 5-HT
Altered expression of CD4+CD25+ regulatory T cells and its 5-HT1a receptor in patients with major depression disorder
Keywords: Major depression; 5-HT; 5-HT1aR; CD4+CD25+ regulatory T cells; Foxp3; Immune imbalance
Serotonin 2C receptor signaling in a diffuse neuronal network is necessary for LPS anorexia
Keywords: A1; A1noradrenergic area of the ventrolateral medulla; Arc; arcuate nucleus of the hypothalamus; CeA; central nucleus of the amygdale; DR; dorsal raphe nucleus; MnR; median raphe nucleus; α-MSH; α-melanocyte-stimulating hormone; NTS; nucleus tractus sol
The nucleus raphe magnus suppresses vomiting, and the solitary nucleus and 5-HT are not involved in this suppression
Keywords: Vomiting; Vagus nerve; Nucleus raphe magnus; Nucleus of the solitary tract; Descending inhibitory system of pain; 5-HT; Ondansetron; 1-(m-chlorophenyl)-biguanade hydrochloride; 5-HT3 receptor;
Dorsal vagal preganglionic neurons: Differential responses to CCK1 and 5-HT3 receptor stimulation
Keywords: DMV, dorsal motor nucleus of the vagus; CCK, cholecystokinin; 5-HT, serotonin; NTS, nucleus of the solitary tract; PBG, phenylbiguanideDorsal motor nucleus of the vagus; CCK; 5-HT
Serotonin upregulates low- and high-threshold tetrodotoxin-resistant sodium channels in the same subpopulation of rat nociceptors
Keywords: NaV1.8; NaV1.9; hyperalgesia; sensory neuron; dorsal root ganglion; A-D/D-A; analog to digital/digital to analog; CP; conditioning potential; DRG; dorsal root ganglion; EGTA; ethylene glycol tetraacetic acid; GTP; guanosine triphosphate; HEPES; 4-(2-hydro
Indirubins deplete striatal monoamines in the Intact and MPTP-treated mouse brain and block kainate-induced striatal astrogliosis
Keywords: 6BIO; 6-bromoindirubin-3â²-oxime; 5BIO; 5-bromoindirubin-3â²-oxime; 5A6BI; 5-amino-6-bromoindirubin; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin/5-hydroxytryptamine; AhR; aryl hydrocarbon receptor; BSA; bovine serum albumin; CDK; cyclin-dependen
Research reportPeripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression
Keywords: UCMS; unpredictable chronic mild stress; TRP; tryptophan; KYN; kynurenine; 5-HT; serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; KP; kynurenine pathway; 3HK; 3-hydroxykynurenine; QUIN; quinolinic acid; ANA; anthranilic acid; 3-HANA; 3-hydroxyanthranilic ac
Visceral hypersensitivity induced by activation of transient receptor potential vanilloid type 1 is mediated through the serotonin pathway in rat colon
Keywords: TRPV1; 5-HT; Visceral hypersensitivity; Colon; Capsaicin
Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia
Keywords: PD; Parkinson's disease; 5-HT; 5-hydroxytryptamine; TPH; tryptophan hydroxylase; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride; 6-OHDA; 6-hydroxydopamine; Serotonin; Tryptophan hydroxylase; Primate; L-DOPA; Dyskinesia;
Rotating disk electrode voltammetric measurements of serotonin transporter kinetics in synaptosomes
Keywords: Rotating disk electrode; Voltammetry; Serotonin; 5-HT; Transporter; Uptake; Serotonin transporter; 5-HTT; SERT knockout
Somatodendritic serotonin release and re-uptake in mouse embryonic stem cell-derived serotonergic neurons
Keywords: Embryonic stem cells; Differentiation; Serotonin; 5-HT; Somatodendritic; Bassoon
Dexamethasone enhances the norepinephrine-induced ERK/MAPK intracellular pathway possibly via dysregulation of the α2-adrenergic receptor: Implications for antidepressant drug mechanism of action
Keywords: 5-HT; serotonin; AP-1; activator protein 1; AR; adrenergic receptor; BDNF; brain derived neurotrophic factor; DEX; dexamethasone; FCS; fetal calf serum; GC; glucocorticoid; GPCR; G-protein-coupled receptor; GR; glucocorticoid receptor; GRK; G-protein rece
Major depression, cognitive dysfunction and Alzheimer's disease: Is there a link?
Keywords: 5-HT; serotonin; Aβ; Amyloid-β; CRH; corticotrophin-releasing hormone; GCs; glucocorticoids; GR; glucocorticoid receptor; HPA; hypothalamus-pituitary-adrenal; MR; mineralocorticoid receptor; NFT; neurofibrillary tangles; Major depression; Alzheimer'
Urocortin 2 increases c-Fos expression in serotonergic neurons projecting to the ventricular/periventricular system
Keywords: 5-HT; 5-Hydroxytryptamine; Cerebral aqueduct; Cerebrospinal fluid; Corticotropin-releasing factor; CRF; CRH; Lateral ventricle; Serotonin; Third ventricle
Swim stress differentially blocks CRF receptor mediated responses in dorsal raphe nucleus
Keywords: Dorsal raphe nucleus; Swim stress; Serotonin; 5-HT; Non-5-HT; mIPSC; GABA; GABAA receptor; CRF1; CRF2
Rose Bengal analogs and vesicular glutamate transporters (VGLUTs)
Keywords: ACPD; trans-(1S,3R)-1-amino-1,3-cyclopentanedicarboxylic acid; AD; Alzheimer disease; ADP; adenosine-diphosphate; ATP; adenosine-triphosphate; CNS; central nervous system; Glu; glutamate; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DMF; dimethylformamide; DM
Serotonergic potentiation of photic phase shifts: examination of receptor contributions and early biochemical/molecular events
Keywords: suprachiasmatic nucleus; 5-HT; fos; period genes; P-ERK; P-CREBANOVA, analysis of variance; cAMP, cyclic adenosine monophospate; CRE, cAMP response element; CREB, cAMP response element binding protein; CT, circadian time; DAB, diaminobenzidine; DD, consta
Interferon-gamma deficiency modifies the effects of a chronic stressor in mice: Implications for psychological pathology
Keywords: 5-HIAA; 5-hydroxyindole acetic acid; 5-HT; serotonin; ANOVA; analysis of variance; BCG; Bacille Calmette-Guérin; CeA; central amygdaloid nucleus; DA; dopamine; DOPAC; dihydroxyphenylacetic acid; EDTA; disodium ethylenediamine tetraacetate; HPA; hypothala
Pharmacological Management of Diarrhea
Keywords: Diarrhea; Secretory diarrhea; Secretion; Enkephalinase inhibitors; Vasoactive intestinal polypeptide; 5-HT;
The role of serotonin in respiratory function and dysfunction
Keywords: 5-HT; Respiratory rhythm; Neurodegeneration; Development; Respiratory disorders
Release of 5-Hydroxytryptamine From the Mucosa Is Not Required for the Generation or Propagation of Colonic Migrating Motor Complexes
Keywords: CMMC; colonic migrating motor complexes; 5-HT; 5-hydroxytryptamine;
Affinity of aporphines for the human 5-HT2A receptor: Insights from homology modeling and molecular docking studies
Keywords: Nantenine; Aporphine; Serotonin; MDMA; 5-HT2A; 5-HT; 5-hydroxytryptamine, serotonin; AcOH; acetic acid; Boc; tert-butoxycarbonyl; BLAST; Basic Local Alignment Search Tool; BRho; bovine rhodopsin; CDI; 1,1â²-carbonyldiimidazole; D; aspartic acid; DCM; dic
Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists
Keywords: 5-HT; 5-Hydroxytryptamine; Serotonin; 5-HT4 antagonist; Hydrophilic; Indole amide; Indole ester; Prodrug esters
SDF-1α/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus
Keywords: Chemokine; 5-HT; GABA; Glutamate; Electrophysiology; Immunohistochemistry; Dorsal raphe nucleusACSF, artificial cerebrospinal fluid; Aq, aqueduct; CNS, central nervous system; DL, double-labeled; DM, dorsomedial; DNQX, 6,7-dinitroquinoxaline-2,3(1H, 4H)-d
The rotational model and microdialysis: Significance for dopamine signalling, clinical studies, and beyond
Keywords: CNS; Central nervous system; COMT; catechol-o-methyl transferase; CYP; Cytochrome P450; DA; Dopamine; ED; Electrochemical detector; GABA; γ-Aminobutyric acid; G proteins; Guanine nucleotide binding proteins; GTP; Guanine triphosphate; HPLC; High performa
Possible anti-obesity therapeutics from nature - A review
Keywords: ACC; acetyl-CoA carboxylase; AMPK; adenosine 5â²-monophosphate-activated protein kinase; BAT; brown adipocyte tissue; C/EBP; CCAAT enhancer binding protein; CNS; central nervous system; CPT; carnitine palmitoyltransferase-1; DHA; docosahexaenoic acid; EC
The synaptic connectivity that underlies the noxious transmission and modulation within the superficial dorsal horn of the spinal cord
Keywords: AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic; CB; calbindin-D28K; CGRP; calcitonin gene-related peptide; CTb; cholera toxin subunit b; CVLM; caudal ventrolateral medulla; DLF; dorsolateral fasciculus; DOR; δ-opioid receptor; DR; dorsal root;
5-HT2A receptor mediated neuronal activation within the paraventricular nucleus of the hypothalamus is desensitized following prolonged glucocorticoid treatment
Keywords: HPA axis; Corticosterone; 5-HT; Raphe; Fos; Depression
Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors
Keywords: 5-HT; TPH1; Tryptophan hydroxylase; Gastrointestinal disorders
Discovery of a new series of monoamine reuptake inhibitors, the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ols
Keywords: Vasomotor symptoms; Monoamine reuptake inhibitor; Norepiephrine reuptake inhibitor; NRI; NE; 5-HT
Effects of 5-HT in globus pallidus on haloperidol-induced catalepsy in rats
Keywords: Globus pallidus; 5-HT; Haloperidol; Catalepsy
Serotonin 5-HT2C receptor-independent expression of hypothalamic NOR1, a novel modulator of food intake and energy balance, in mice
Keywords: NR4A; NOR1; Hypothalamus; Obesity; Food intake; Leptin receptor; 5-HT2C receptor; 5-HT; β-Endorphin; Proopiomelanocortin-derived peptides
Partial regulation of serotonin transporter function by γ-synuclein
Keywords: 5-HT; serotonin; SERT; serotonin transporter; α-Syn; α-synuclein; γ-Syn; γ-synuclein; β-Syn; β-synuclein; co-IP; co-immunoprecipitation; IMP; imipramine; Depression; Mood disorders; Monoamine transporters; γ-Synuclein; Serotonin transporter; Raphe
Lack of differential serotonin biosynthesis capacity in genetically selected low and high aggressive mice
Keywords: 5-HT; TPH; Aggression; 5-HTP; Violence; Genetic selection
Parallel processing in mammalian taste buds?
Keywords: Taste transmitters; ATP; Serotonin; 5-HT; Noradrenalin; Pannexin 1; Cephalic phase digestion; Taste receptor cells; Taste bud synapses
Intracolonical administration of protease-activated receptor-2 agonists produced visceral hyperalgesia by up-regulating serotonin in the colon of rats
Keywords: Visceral hyperalgesia; Protease-activated receptor (PAR); Serotonin; PAR-2; 5-HT; EC cell