Serotonin inhibits GABA synaptic transmission in presympathetic paraventricular nucleus neurons
Keywords: 5-HT; GABA; Sympathetic outflow; Paraventricular nucleus; 5-HT1A receptor
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Motor activity induces release of serotonin in the dorsal horn of the rat lumbar spinal cord
Keywords: Microdialysis; Spinal cord; Exercise; Motor function; 5-HT
The combination of human neuronal serotonergic cell implants and environmental enrichment after contusive SCI improves motor recovery over each individual strategy
Keywords: Cell line; Combination therapy; 5-HT; Excitatory neurotransmitter; Human; EE; Neuronal; Preclinical; NT2
Decreased [18F]MPPF Binding Potential in the Dorsal Raphe Nucleus After a Single Oral Dose of Fluoxetine: A Positron-Emission Tomography Study in Healthy Volunteers
Keywords: Antidepressants; brain imaging; DRN; 5-HT; 5-HT1A receptors; 5-hydroxytryptamine; internalization; serotonin; SSRI treatment
2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists
Keywords: Serotonin; 5-HT2A; 5-HT2B; 5-HT2C; 5-HT
Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: Structure–activity relationship elucidation
Keywords: 5-HT; GPCR; SAR; Guanidine
5-HT reuptake and 5-HT2 receptors modulate capsaicin-evoked hypothermia in rats
Keywords: Capsaicin; TRPV1; 5-HT; Serotonin; Hypothermia; Fluoxetine
Developmental expression and serotonergic regulation of relaxin 3/INSL7 in the nucleus incertus of rat brain
Keywords: Relaxin 3; 5-HT; In situ hybridization; 5-HT1A; NI; Rat;
Relationship of the serotonin transporter with prolactin response to meta-chlorophenylpiperazine in cocaine dependence
Keywords: Serotonin transporter; 5-HT; m-CPP; Cocaine; Substance abuse
Brainstem monoamine pathology of neonatal hypoxic-ischemic brain damage: A model of acute stage of neonatal asphyxia
Keywords: HIE; hypoxic-ischemic encephalopathy; TH; tyrosine hydroxylase; TpH; tryptophan hydroxylase; NE; norepinephrine; 5-HT; serotonin; HVA; homovanillic acid; 5HIAA; 5-hydroxyindoleacetic acid; HPLC; high-performance liquid column; GFAP; glial fibrillary aci
Social hierarchies, growth and brain serotonin metabolism in Atlantic salmon (Salmo salar) kept under commercial rearing conditions
Keywords: Brain; Dominance; Growth; Hierarchy; 5-HT; Stress; Salmon; Salmo salar; Social groups
Activation of the serotonergic 5-HT1A receptor in the paraventricular nucleus of the hypothalamus inhibits water intake and increases urinary excretion in water-deprived rats
Keywords: PVN; Water intake; Urinary excretion; 5-HT; 8-OH-DPAT; pMPPF;
Rhesus monkey tryptophan hydroxylase-2 coding region haplotypes affect mRNA stability
Keywords: TPH2; 5-HT; nonsynonymous polymorphisms; gene expression; nonhuman primate; AA; amino acid; ADHD; attention deficit hyperactivity disorder; ANOVA; analysis of variance; CDSN; corneodesmosin; CSTA; cystatin A; DRB; 5,6-dichlororibofuranosyl benzimidazole;
Research ReportRegulation of extracellular serotonin levels and brain-derived neurotrophic factor in rats with high and low exploratory activity
Keywords: 5-HT; serotonin; LE; low exploratory activity; HE; high exploratory activity; PFC; prefrontal cortex; DG; dentate gyrus; HI; hippocampus; PCA; parachloroamphetamine; 5-HTT; serotonin transporter; BDNF; brain-derived neurotrophic factor; NGF; nerve growth
Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function
Keywords: 5-HT; Serotonin; 5-HTT; SERT; 5-HT2A; Genetic variation; Transgenic
Neurochemical differentiation of horizontal and amacrine cells during transformation of the sea lamprey retina
Keywords: 5-HT; 5-hydroxytryptamine (serotonin); DA; dopamine; GABA; γ-aminobutyric acid; Gly; glycine; HCL; horizontal cell layer; INL; inner nuclear layer; IPL; inner plexiform layer; M; metamorphosis; M1-M7; metamorphic stages; ONL; outer nuclear layer; OPL;
Associations between increases in plasma n-3 polyunsaturated fatty acids following supplementation and decreases in anger and anxiety in substance abusers
Keywords: AA; arachidonic acid; ALA; alpha-linolenic acid; ASI; Addiction Severity Index questionnaire; DHA; docosahexaenoic acid; DPA; docosapentaenoic acid; EPA; eicosapentaenoic acid; 5-HIAA; 5-Hydroxyindole Acetic Acid; 5-HT; serotonin; FA; fatty acid; LA; lino
NMDA and GABAB receptors are involved in controlling nematocyst discharge in hydra
Keywords: Acetylcholine; Chemical neurotransmission; Cnidaria; Dopamine; 5-HT; GABA; Glutamate; Glycine
The role of 5-HT receptor subtypes in the ventrolateral orbital cortex of 5-HT-induced antinociception in the rat
Keywords: 5-HT; 5-HT receptor; ventrolateral orbital cortex; antinociception; tail flick reflex; rat; AUC; areas under the curve; CPT; cyproheptadine hydrochloride; DRN; dorsal raphe nucleus; GR 113808; 1-[2-[(methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl1-meth
NAN-190 potentiates the circadian response to light and speeds re-entrainment to advanced light cycles
Keywords: 5-HT; circadian; rhythm; jet-lag; entrainment; phase shift; CT; circadian time; LD; light/dark; SCN; suprachiasmatic nucleus; ZT; zeitgeber time;
Treadmill exercise enhances passive avoidance learning in rats: The role of down-regulated serotonin system in the limbic system
Keywords: One-trial passive avoidance task; 5-HT; 5-HT1A receptor; Amygdala; Hippocampus
Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan
Keywords: BBB; blood brain barrier; 5-HT; serotonin; DCVs; dense core vesicles; SC; subcutaneous; IT; intrathecal; 5-HT1D-IR; 5-HT1D receptor immunoreactivity; Migraine; Headache; Inflammation; Serotonin; Sumatriptan; Intrathecal; Blood brain barrier;
Superoxide modifies AMPA receptors and voltage-gated K+ channels of mouse hippocampal neurons
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid; DTT; dithiothreitol; GABA; γ-aminobutyric acid; 5-HT; 5-hydroxytryptamine; LY; Lucifer Yellow CH; NMDA; N-methyl-d-aspartate; SOD; superoxide dismutase; TEA; tetraethylammonium; TTX; tetrodoto
The effects of photic and nonphotic stimuli in the 5-HT7 receptor knockout mouse
Keywords: agonist; circadian; entrainment; light; re-entrainment; 5-HT; CT; circadian time; DD; dark/dark; KO; knockout; LD; light/dark; PRC; phase response curve; rev/day; revolutions/day; RHT; retinohypothalamic tract; SCN; suprachiasmatic nuclei; WT; wild type;
Δ9-Tetrahydrocannabinol-induced catalepsy-like immobilization is mediated by decreased 5-HT neurotransmission in the nucleus accumbens due to the action of glutamate-containing neurons
Keywords: Δ9-tetrahydrocannabinol; catalepsy; nucleus accumbens; 5-HT; glutamateA, anterior to the bregma; ACE, central amygdala; ANOVA, analysis of variance; CP, caudate putamen; DRN, dorsal raphe nucleus; GP, globus pallidus; HPD, haloperidol; L, lateral to the m
Activation of the ventral medial prefrontal cortex during an uncontrollable stressor reproduces both the immediate and long-term protective effects of behavioral control
Keywords: stress resilience; learned helplessness; 5-HT; dorsal raphe nucleus; microdialysis; picrotoxinANOVA, analysis of variance; DRN, dorsal raphe nucleus; ES, escapable stress; FR-1, fixed ratio-1; HCC, home cage controls; IS, inescapable shock; PIC, picrotoxi
Reduced 5-HT2A receptor binding in patients with mild cognitive impairment
Keywords: Alzheimer's disease; Mild cognitive impairment; Serotonin; Neuroreceptor; 5-HT; 5-HT2A; PET; Altanserin
Reduced sensitivity to MDMA-induced facilitation of social behaviour in MDMA pre-exposed rats
Keywords: MDMA; 3,4-methylenedioxymethamphetamine; 8-OH-DPAT; (±)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide; 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid.; HPLC; high-performance liquid chromatography.; 5-HT1A; 8-OH-DPAT; Anxiety; Behaviour
Neuromodulation and the orchestration of the respiratory rhythm
Keywords: Respiratory rhythm; Pre-BötC; Neuromodulator; 5-HT; Norepinephrine; Substance P
Serotonin transporter binding and acquired obesity — An imaging study of monozygotic twin pairs
Keywords: SPECT5; 5-HT; SERT; 5-HTTLPR; radioligand; [123I]nor-β-CIT; twin study; BMI
Pharmacological MRI in animal models: A useful tool for 5-HT research?
Keywords: Magnetic resonance imaging; 5-HT; Pharmacological MRI; Rat
Actions of 3,4-methylenedioxymethamphetamine (MDMA) on cerebral dopaminergic, serotonergic and cholinergic neurons
Keywords: Microdialysis; MDMA; 5-HT; Dopamine; Acetylcholine; Glucose
Th2 Cytokine-Induced Alterations in Intestinal Smooth Muscle Function Depend on Alternatively Activated Macrophages
Keywords: 5-HT; 5-hydroxytryptamine; AAMÏ; alternatively activated macrophage; BEC; S-(2-boronoethyl)-I-cysteine; CAMÏ; classically activated macrophage; Cl2MDP; clodronate; FIZZ; found in inflammatory zone; IFN-γ; interferon-γ; IGF-1; insulin-like growth facto
ReviewThe function of serotonin within the liver
Keywords: 5-HIAA; 5-hydroxyindoleacetaldehyde; 5-HT; 5-hydroxytryptamine; ANS; autonomic nervous system; BDEC; bile duct epithelial cell; CNS; central nervous system; ECM; extracellular matrix; ERK1/2; extracellular regulated kinase 1/2; GI; gastrointestinal; HSC;
Effects of 5-Hydroxytryptamine (Serotonin) Type 3 Antagonists on Symptom Relief and Constipation in Nonconstipated Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Keywords: CI; confidence interval; D-IBS; diarrhea-predominant irritable bowel syndrome; 5-HT; 5-hydroxytryptamine (serotonin); I2; measure of study inconsistency; IBS; irritable bowel syndrome; NC-IBS; nonconstipated irritable bowel syndrome; RR; relative risk;
Research ReportCellular localization of P2X7 receptor mRNA in the rat brain
Keywords: 2-AG; 2-arachidonoylglycerol; 3V; third ventricle; 4V; fourth ventricle; 5-HT; serotonin; AOD; anterior olfactory nucleus, dorsal part; AOL; anterior olfactory nucleus, lateral part; AOM; anterior olfactory nucleus, medial part; AOV; anterior olfactory nu
Sub-chronic nandrolone treatment modifies neurochemical and behavioral effects of amphetamine and 3,4-methylenedioxymethamphetamine (MDMA) in rats
Keywords: Amphetamine; Anabolic steroids; Dopamine; MDMA; Nucleus accumbens; 5-HT
Tolerance to 3,4-methylenedioxymethamphetamine in rats exposed to single high-dose binges
Keywords: ecstasy; 5-HT; dopamine; transporter; neuroendocrine; microdialysisaCSF, artificial cerebrospinal fluid; ACTH, adrenocorticotropin; ANOVA, analysis of variance; DA, dopamine; HPLC-ECD, high-performance liquid chromatography with electrochemical detection;
Characterization of Fetal and Postnatal Enteric Neuronal Cell Lines With Improvement in Intestinal Neural Function
Keywords: α-SMA; α-smooth muscle actin; BrdU; bromodeoxyuridine; DAPI; 4',6-diamidino-2-phenylindole; EFS; electrical field stimulation; ENS; enteric nervous system; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GDNF; glial cell line-derived neurotrophic fac
Hippocampal interneurons co-express transcripts encoding the α7 nicotinic receptor subunit and the cannabinoid receptor 1
Keywords: CB1; 5-HT3 receptors; 5-HT; CCK; Alzheimer’s disease; schizophreniaBSA, bovine serum albumin; CB1, cannabinoid receptor type 1; CCK, cholecystokinin; DEPC, diethyl pyrocarbonate; DG, dentate gyrus; GAD, glutamate decarboxylase; nACh, nicotinic acetylcholi
Neuroprotective actions of ovarian hormones without insult in the raphe region of rhesus macaques
Keywords: estrogen; 5-HT; apoptosis; neuroprotection; AIF; JNKAIF, apoptosis inducing factor; Apaf1, apoptotic peptidase activating factor 1; cDNA, complementary DNA; DRN, dorsal raphe nucleus; E, estrogen; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; HT, hormo
Acute ethanol modulates glutamatergic and serotonergic phase shifts of the mouse circadian clock in vitro
Keywords: suprachiasmatic nucleus; circadian rhythms; ethanol; glutamate; 5-HT; brain-derived neurotrophic factorAP5, aminophosphovaneric acid; BDNF, brain-derived neurotrophic factor; DPAT, (+)8-hydroxy-2-(di-N-propylamino)tetralin; EBSS, Earle’s Balanced Salt Sol
Inactivation of median preoptic nucleus causes c-Fos expression in hypocretin- and serotonin-containing neurons in anesthetized rat
Keywords: aCSF; Artificial cerebrospinal fluid; DRN; Dorsal raphe nucleus; Fos-IR; c-fos protein immunoreactivity; GABA; Gamma-aminobutyric acid; GAD; Glutamic acid decarboxylase, a marker for GABAergic neurons; HCRT; Hypocretin; MCH; Melanin-concentrating hormone;
Modulation of cholinergic functions by serotonin and possible implications in memory: General data and focus on 5-HT1A receptors of the medial septum
Keywords: 5-HT; 5-HT1A receptor; 192 IgG-saporin; Acetylcholine; Cognition; GABA; Hippocampus; Septum
Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: Persisting effects on locomotor activity, learning and nicotine self-administration
Keywords: 6-OHDA; radial-arm maze; dopamine; 5-HT; nucleus accumbens; striatumACSF, artificial cerebrospinal fluid; DA, dopaminergic; VTA, ventral tegmental area; 6-OHDA, 6-hydroxydopamine
5-HT excites globus pallidus neurons by multiple receptor mechanisms
Keywords: 5-HT; 5-HT receptors; globus pallidusACSF, artificial cerebrospinal fluid; AP5, (±)-2-amino-5-phosphonopentanoic acid; CGP55845, (2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino-2-hydroxylpropyl] (phenylmethyl) phosphinic acid; CNQX, 6-cyano-7-nitroquino x
The impact of ziprasidone in combination with sertraline on visually-evoked event-related potentials in depressed patients with psychotic features
Keywords: DSM; Diagnostic and Statistical Manual of Mental Disorders; EEG; electroencephalographie; EOG; electro-oculography; ERP; event-related potentials; mg/d; milligram per day; msec; millisecond; SSRI; selective serotonin reuptake inhibitor; μg/l; microgram p
Serotonin but not zonisamide inhibits theophylline-induced epileptiform activity in guinea pig hippocampal CA3 neurons
Keywords: Epilepsy; Serotonin; Theophylline; Zonisamide; 5-HT
The Dual Serotonin and Noradrenaline Reuptake Inhibitor Duloxetine for the Treatment of Interstitial Cystitis: Results of an Observational Study
Keywords: cystitis; interstitial; pelvic pain; duloxetine; antidepressive agents; clinical trial; 5-HT; 5-hydroxytryptamine = serotonin; AE; adverse event; GRA; global response assessment; IC; interstitial cystitis; ICSI; Interstitial Cystitis Symptom Index; NA; no
Studies on a series of potent, orally bioavailable, 5-HT1 receptor ligands
Keywords: 5-HT; Serotonin; Depression; Autoreceptors;