دانلود مقالات ISI درباره 6-Hydroxydopamine + ترجمه فارسی

The sources of salidroside and its targeting for multiple chronic diseases

Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid protein; MPTP; 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine; MPP+; N-methyl-4-phenylpyridine; AD; Alzheimer's disease; PD; Parkinson's disease; STZ; streptozotocin; PI3K; phosphatidylinositol 3-kinase; ROS; react

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2020 سفارش ترجمه

Immunohistochemical changes of nigrostriatal tyrosine hydroxylase and dopamine transporter in the golden hamster after a single intrastriatal injection of 6-hydroxydopamine

Keywords: Golden hamster; 6-Hydroxydopamine; Striatum; Substantia nigra pars compacta; Tyrosine hydroxylase; Dopamine transporter

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Losartan pretreatment reduces neurodegeneration and behavioural symptoms in 6-hydroxydopamine induced unilateral rat model of Parkinson's disease

Keywords: Losartan; Oxidative stress; Rotational behaviour; 6-Hydroxydopamine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Alpha-lipoic acid protects against 6-hydroxydopamine-induced neurotoxicity in a rat model of hemi-parkinsonism

Keywords: Alpha-lipoic acid; Parkinson's disease; 6-hydroxydopamine; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The effects of voluntary running exercise coincidence with social isolation after early weaning on monoaminergic axonal development

Keywords: 5-HT; serotonin; 6-OHDA; 6-hydroxydopamine; A; anterior; ANOVA; analysis of variance; BLA; basolateral nucleus of amygdala; DA; dopamine; DBH; dopamine β-hydroxylase; DG; dentate gyrus; DR; dorsal raphe; EI; early weaning/social isolation; IR; immunoreac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The roles of cyclic AMP–ERK–Bad signaling pathways on 6-hydroxydopamine-induced cell survival and death in PC12 cells

Keywords: 6-Hydroxydopamine; Cyclic AMP; Extracellular signal-regulated kinase (ERK); Bad; PC12 cells

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Striatal TH-immunopositive fibers recover after an intrastriatal injection of 6-hydroxydopamine in golden hamsters treated with prednisolone: Roles of tumor necrosis factor-α and inducible nitric oxide synthase in neurodegeneration

Keywords: Golden hamster; 6-Hydroxydopamine; Striatal Recovery; Activated microglia; Prednisolone; Minocycline; TNF-α; iNOS;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Arylpiperazine-mediated activation of Akt protects SH-SY5Y neuroblastoma cells from 6-hydroxydopamine-induced apoptotic and autophagic death

Keywords: Arylpiperazine; 6-Hydroxydopamine; Neuroprotection; Akt; Autophagy; Apoptosis6-OHDA, 6-hydroxydopamine; AMPK, AMP-activated protein kinase; DHE, dihydroethidium; ERK, extracellular signal-regulated kinase; JNK, Jun-N-terminal kinase; LC3, microtubule-asso

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Rotenone-induced neurotoxicity in rat brain areas: A study on neuronal and neuronal supportive cells

Keywords: ANOVA; one way analysis of variance; BSA; bovine serum albumin; DMSO; dimethyl sulphoxide; EDTA; ethylenediamine tetraacetic acid; GFAP-ir; glial fibrillary acidic protein immunoreactivity; IF; immunofluorescence; ir; immunoreactivity; MB; mid brain; LPS;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Differential striatal spine pathology in Parkinson's disease and cocaine addiction: A key role of dopamine?

Keywords: 6-OHDA; 6-hydroxydopamine; CaM; Calmodulin; cAMP; cyclic AMP; CaN; Calcineurin; Cdk5; cyclin-dependent kinase 5; DA; dopamine; GP; globus pallidus; MEF2; myocyte enhancer factor 2; MSNs; medium spiny neurons; NAc; nucleus accumbens; PD; Parkinson's dise

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

Separation of intermediates of iron-catalyzed dopamine oxidation reactions using reversed-phase ion-pairing chromatography coupled in tandem with UV-visible and ESI-MS detections

Keywords: Reversed-phase ion-pairing chromatography; Electrospray ionization-mass spectrometry; Dopamine oxidation; 6-Hydroxydopamine; Short-lived intermediates;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Protective effects of urate against 6-OHDA-induced cell injury in PC12 cells through antioxidant action

Keywords: PD; Parkinson's disease; 6-OHDA; 6-hydroxydopamine; 8-OHdG; 8-hydroxy-deoxyguanosine; GSH; glutathione; MDA; malondialdehyde; LDH; lactate dehydrogenas; SOD; superoxide dismutase; 6-Hydroxydopamine (6-OHDA); Urate; Oxidative stress; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Chronic dopamine depletion augments the functional expression of K-ATP channels in the rat subthalamic nucleus

Keywords: STN; subthalamic nucleus; NMDA; N-methyl-d-aspartate; K-ATP; ATP-sensitive K+; 6-OHDA; 6-hydroxydopamine; ANOVA with RM; analysis of variance with repeated measures; ATP-sensitive K+ channel; Subthalamic nucleus; N-Methyl-d-aspartate; Sulfonylurea; Tolbut

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Intranasally applied l-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions

Keywords: Intranasal l-DOPA; 6-Hydroxydopamine; Benserazide; Turning behavior; Footslips; Forelimb use

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP+, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells

Keywords: [Ca2+]i; intracellular calcium concentration; DAT; dopamine transporter; DBH; dopamine-β-hydroxylase; DCFH-DA; 2,7-dichlorofluorescein diacetate; DMEM/F-12; Dulbecco's modified eagle medium nutrient mixture F-12; DMSO; dimethyl sulfoxide; FBS; fetal bovi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Functional neuroimaging of the 6-OHDA lesion rat model of Parkinson's disease

Keywords: [18F]-fluoro-2-deoxy-d-glucose; 6-Hydroxydopamine; Parkinson's disease; Positron emission tomography;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of the canonical Wnt pathway by Dickkopf-1 contributes to the neurodegeneration in 6-OHDA-lesioned rats

Keywords: Dickkopf-1; 6-Hydroxydopamine; rat; Parkinson's disease; Wnt signaling pathway;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

High intake of folic acid or complex of B vitamins provides anti-Parkinsonism effect: No role for serum level of homocysteine

Keywords: 6-Hydroxydopamine; Plasma Hcy; Folate, B complex; B12; B6

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Dorsal striatal dopamine depletion impairs both allocentric and egocentric navigation in rats

Keywords: Dopamine; Route-based learning; Spatial learning; 6-Hydroxydopamine; Egocentric; Allocentric; Striatum;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

IGF-I receptor signaling pathway is involved in the neuroprotective effect of genistein in the neuroblastoma SK-N-SH cells

Keywords: Genistein; 6-hydroxydopamine; Insulin-like growth factor I receptor; SK-N-SH cell

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The grid-walking test: assessment of sensorimotor deficits after moderate or severe dopamine depletion by 6-hydroxydopamine lesions in the dorsal striatum and medial forebrain bundle

Keywords: 6-OHDA; grid-walking; foot-slips; medial forebrain bundle; dorsal striatum; hemiparkinsonian rats; DOPAC; 3,4-dihydroxyphenylacetic acid; dSTR; dorsal striatum; HVA; homovanillic acid; MFB; medial forebrain bundle; PD; Parkinson's disease; 6-OHDA; 6-hydro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Basic NeuroscienceA novel use of combined tyrosine hydroxylase and silver nucleolar staining to determine the effects of a unilateral intrastriatal 6-hydroxydopamine lesion in the substantia nigra: A stereological study

Keywords: HPLC-EC; high-performance liquid chromatography-electrochemical detection; 6-OHDA; 6-hydroxydopamine; NOR; nucleolar organizing region; AgNOR; silver nucleolar; SNpc; substantia nigra pars compacta; TH; tyrosine hydroxylase; TH-AgNOR; tyrosine hydroxylase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research reportDeep brain stimulation of the subthalamic nucleus in the 6-hydroxydopamine rat model of Parkinson's disease: Effects on sensorimotor gating

Keywords: 6-OHDA; 6-hydroxydopamine; ANOVA; analysis of variance; ASR; acoustic startle response; BG; basal ganglia; BSA; bovine serum albumin; DA; dopamine; DAB; 33′-diaminobenzidin; DBS; deep brain stimulation; PBS; phosphate buffered saline; PFA; paraformaldeh

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Zonisamide up-regulated the mRNAs encoding astrocytic anti-oxidative and neurotrophic factors

Keywords: Zonisamide; Dopamine neuron; Astrocyte; Slice culture; 6-Hydroxydopamine; (Rat);

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

SF-6 attenuates 6-hydroxydopamine-induced neurotoxicity: An in vitro and in vivo investigation in experimental models of Parkinson's disease

Keywords: α-Synuclein; 6-Hydroxydopamine; Reactive oxygen species; Parkinson's disease; Indigofera tinctoria;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Fibroblast growth factor-20 protects against dopamine neuron loss in vitro and provides functional protection in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease

Keywords: Dopamine; Fibroblast growth factor; FGF-20; 6-Hydroxydopamine; Locomotion; Nigrostriatal tract; Parkinson's disease; Ventral mesencephalon

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Anxiety in Parkinson's disease: A critical review of experimental and clinical studies

Keywords: Parkinson's disease; Anxiety; Clinical studies; Animal models; Review; BLA; basolateral nucleus of the amygdala; BDZs; benzodiazepines; CNS; central nervous system; DSM; Diagnostic and Statistical Manual of Mental Disorders; DA; dopamine; DOPAC; 3,4-dih

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The power of life-Cytochrome c oxidase takes center stage in metabolic control, cell signalling and survival

Keywords: ATP; adenosine 5′-triphosphate; COX; cytochrome c oxidase; Δpm; proton motive force; ΔΨm; mitochondrial membrane potential; H2S; hydrogen sulphur; MPP+; 1-methyl-4-phenylpyridinium; NO; nitric oxide; NPA; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopam

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)

Keywords: ARE; Antioxidant response element; DCF; 2′,7′-dichlorofluorescein; DDC; 2′,3′-dihydroxy-4′,6′-dimethoxychalcone; DHE; Dihydroethidium; DMSO; Dimethyl sulfoxide; EI; Electron impact; ETH; Ethidium; γ-GCS; ⁎γ-glutamylcysteine synthetase; G

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Striatal inhibition of calpains prevents levodopa-induced neurochemical changes and abnormal involuntary movements in the hemiparkinsonian rat model

Keywords: Parkinson's disease; 6-Hydroxydopamine; Levodopa; Dyskinesia; Caudate-putamen; cdk5; Calpains;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: Predicting l-DOPA-induced dyskinesia

Keywords: l-3,4-dihydroxyphenylalanine; Dyskinesia; 6-Hydroxydopamine; TH; 5-HT; FosB

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Impact of L-DOPA treatment on regional cerebral blood flow and metabolism in the basal ganglia in a rat model of Parkinson's disease

Keywords: AIB; [14C]-aminoisobutyric acid; AIMs; abnormal involuntary movements; BBB; blood-brain barrier; DA; dopamine; 2-DG; [14C]-2-deoxyglucose; IAP; [14C]-iodoantipyrine; KPBS-T; potassium phosphate buffered saline containing 0.25% Triton-X; LID; L-DOPA-indu

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of L-DOPA and STN-HFS dyskinesiogenic treatments on NR2B regulation in basal ganglia in the rat model of Parkinson's disease

Keywords: 6-OHDA; 6-hydroxydopamine; AIMS; abnormal involuntary movements; DA; dopamine; EP; entopeduncular nucleus; L-DOPA; l-3,4-dihydroxyphenylalanine; LID; L-DOPA-induced dyskinesia; NMDA; N-methyl-d-aspartate; PD; Parkinson's disease; SNc; substantia nigra par

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of chronic l-DOPA treatment on 5-HT1A receptors in parkinsonian monkey brain

Keywords: 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; 5-hydroxytryptamine (serotonin); 6-OHDA; 6-hydroxydopamine; 8-OH-DPAT; 8-hydroxy-2-(di-n-propyl) aminotetraline; ac; anterior commissure; AcgG; anterior cingulate gyrus; CA; cornu ammonis; DG; dentate gyrus; DHA;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Chemical and biological evaluation of nephrocizin in protecting nerve growth factor-differentiated PC12 cells by 6-hydroxydopamine-induced neurotoxicity

Keywords: Formosa date palm; Phoenix hanceana Naudin var. formosana; Arecaceae; 6-Hydroxydopamine; H2O2; p-Quinone; Neuroprotection; Nephrocizin; Chemical and biological studies;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

L-DOPA-induced dysregulation of extrastriatal dopamine and serotonin and affective symptoms in a bilateral rat model of Parkinson's disease

Keywords: 5-HT; serotonin; 6-OHDA; 6-hydroxydopamine; ANOVAs; analysis of variances; DA; dopamine; HPLC-ED; high-performance liquid chromatography with electrochemical detection; LD; L-DOPA; L-DOPA; L-3,4-dihydroxyphenylalanine; MFB; medial forebrain bundle; mg; mi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: Motor impairments identify extent of dopamine depletion at three different lesion sites

Keywords: Parkinson's disease; 6-Hydroxydopamine; Mouse; Motor behaviour; Dopamine; Striatum

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death

Keywords: PD; Parkinson disease; DAergic; dopaminergic; DA; dopamine; 6-OHDA; 6-hydroxydopamine; ROS; reactive oxygen species; CM-H2DCFDA; 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate acetyl ester; PML; promyelocytic leukemia; NAC; N-acetyl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse

Keywords: α-syn; α-synuclein; ASK1; Apoptosis signaling-regulating kinase 1; CMA; Chaperone-mediated autophagy; DAT; Dopamine transporter; ETC; Electron transport chain; iPS; Induced pluripotent stem; LAMP-2A; Lysosome-associated membrane protein 2A; LB; Lewy bod

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease

Keywords: 6-OHDA; 6-hydroxydopamine; AIMs; abnormal involuntary movements; AMPARs; AMPA receptors; DA; dopamine; DBS; deep brain stimulation; EP; entopeduncular nucleus; GPe; external segment of the globus pallidus; GLT1; glial glutamate/aspartate transporter 1; GP

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2012 سفارش ترجمه

Closing the gap between clinic and cage: Sensori-motor and cognitive behavioural testing regimens in neurotoxin-induced animal models of Parkinson's disease

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; PACAP; adenylate cyclase activating polypeptide; Aβ; amyloid-β; SNCA [gene]; α-synuclein; α-SYN [protein]; α-synuclein; AD; Alzheimer's disease; CeA; central nucleus of the amygdala; DCS; D

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2012 سفارش ترجمه

Neurotoxin-based models of Parkinson's disease

Keywords: Parkinson's disease; animal models; 6-hydroxydopamine; MPTP; rotenone; paraquatASK1, apoptosis signal-regulating kinase 1; Bax, Bcl2-associated X protein; COMT, catechol-O-methyl transferase; DAT, dopamine transporter; JNK, c-jun N-terminal kinases; l-dop

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of unilateral nigrostriatal dopamine depletion on peripheral glucose tolerance and insulin signaling in middle aged rats

Keywords: Parkinson's disease; Insulin; Glucose; Diabetes; 6-Hydroxydopamine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Lesions of the ventral ascending noradrenergic bundles decrease the stress response to occlusal disharmony in rats

Keywords: Hypothalamus-pituitary-adrenocortical axis; Occlusal disharmony; 6-Hydroxydopamine; Ventral ascending bundles of noradrenergic neurons; Rat;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Differential expression of FosB, c-Fos, and Zif268 in forebrain regions after acute or chronic l-DOPA treatment in a rat model of Parkinson's disease

Keywords: 6-Hydroxydopamine; l-DOPA; Abnormal involuntary movement; Immediate-early gene protein; Immunohistochemistry

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum

Keywords: 6-Hydroxydopamine; Quercetin; Dopamine; Corpus striatum; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Possible regulatory factors for intra-abdominal fat mass in a rat model of Parkinson's disease

Keywords: Parkinson's disease; 6-Hydroxydopamine; Intra-abdominal fat; Fat absorption; Insulin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

In vivo 6-OHDA-induced neurodegeneration and nigral autophagic markers expression

Keywords: 6-Hydroxydopamine; Neurodegeneration; Autophagy; Chaperone; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Knockdown of glycogen synthase kinase 3 beta attenuates 6-hydroxydopamine-induced apoptosis in SH-SY5Y cells

Keywords: 6-Hydroxydopamine; Apoptosis; Glycogen synthase kinase 3 beta; RNA interference

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Parkinson's disease involves autophagy and abnormal distribution of cathepsin L

Keywords: Parkinson's disease; Autophagy; Cathepsin L; 6-Hydroxydopamine; Neurodegeneration

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه