دانلود مقالات ISI درباره AD، بیماری آلزایمر + ترجمه فارسی

Role of mitochondrial homeostasis and dynamics in Alzheimer's disease

Keywords: AD، بیماری آلزایمر; Aβ, beta amyloid; AD, Alzheimer's disease; ADAM10, a disintegrin and metalloproteinase domain-containing protein 10; AMP, adenosine monophosphate; AMPK, AMP kinase; APOE, apolipoprotein E; APP, amyloid precursor protein; ASK1, apoptosis signal-regulating

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Vitamin B12 in neurology and ageing; Clinical and genetic aspects

Keywords: AD، بیماری آلزایمر; Vitamin B12; Neurology; Homocysteine; Methylmalonic acid; Ageing; GeneticsMMA, methylmalonic acid; TC, transcobalamin; AD, Alzheimer's disease; SDAT, senile dementia of Alzheimer type; CSF, cerebrospinal fluid; PD, Parkinson's disease; MS, multiple sclero

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Perivascular, but not parenchymal, cerebral engraftment of donor cells after non-myeloablative bone marrow transplantation

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; ANOVA, analysis of variance; CNS, central nervous system; MyA, myeloablative; NMyA, non-myeloablative; BMT, bone marrow transplant; GCL, ganglion cell layer; GFP, green fluorescent protein; Gy,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

ATR-FTIR: A “rejuvenated” tool to investigate amyloid proteins

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ADDLs, amyloid-beta derived diffusible ligands; ANS, 8-anilino-1-naphthalenesulfonic acid; ATR, Attenuated total reflection; Aβ, Amyloid beta; CD, circular dichroism; EM, electron microscopy; EPR, electron paramagnetic resonance;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Early cognitive stimulation compensates for memory and pathological changes in Tg2576 mice

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; CS, cognitive stimulation; MWM, Morris Water Maze; NOR, novel object recognition; WT, wild-typeCognitive training; hAPP transgenic mouse; Synaptic; Amyloid; Tau

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Microtubule-associated protein tau in bovine retinal photoreceptor rod outer segments: Comparison with brain tau

Keywords: AD، بیماری آلزایمر; AP, alkaline phosphatase; AD, Alzheimer's disease; BSA, bovine serum albumin; Cdk5, cyclin-dependent protein kinase 5; DTT, dithiothreitol; FTDP-17, front-temporal dementia with parkinsonism liked to chromosome; MT, microtubule; MW, molecular weight; PHF,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Tau degradation: The ubiquitin–proteasome system versus the autophagy-lysosome system

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β peptide; AD, Alzheimer's disease; AMPK, adenosine monophosphate-activated protein kinase; ApoE4, apolipoprotein E4; APP, amyloid-β precursor protein; CHIP, Hsc70-interacting protein; CMA, chaperone-mediated autophagy; CP, core particle; DUB,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Axon degeneration in Parkinson's disease

Keywords: AD، بیماری آلزایمر; [3H]TBZOH, tritiated α-dihydrotetrabenazine; 6-OHDA, 6-hydroxydopamine; AAV, adeno-associated virus; AD, Alzheimer's disease; AVs, autophagic vacuoles; DLB, dementia with Lewy Bodies; ILB, incidental Lewy bodies; LB, Lewy body; LRRK2, leucine rich repeat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Aβ42, amyloid-β-42; Aβ40, amyloid-β-40; APP, amyloid precursor protein; BACE1, β-site amyloid precursor protein-cleaving enzyme; BC200 (BCYRN1), brain cytoplasmic RNA 1; BC1, brain cytoplasmic R

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Progranulin promotes activation of microglia/macrophage after pilocarpine-induced status epilepticus

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; BSA, bovine serum albumin; DIV, days in vitro; FJB, fluoro-Jade B; FTLD, frontotemporal lobe dementia; GFAP, glial fibrillary acidic protein; HPLC, high performance liquid chromatography; IL-6,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ42, amyloid-beta (1–42); α-syn, α-synuclein; CL, cardiolipin; Cyto c, cytochrome c; CCR, cytochrome c release; IM and IMM, inner mitochondrial membrane; OM and OMM, outer mitochondrial membrane; OGB-1, Oregon Green® 488 BAPTA-1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Diagnosis and management of Alzheimer's disease: Past, present and future ethical issues

Keywords: AD، بیماری آلزایمر; A4, anti-amyloid treatment of asymptomatic Alzheimer's disease trial; AD, Alzheimer's disease; ADNI, Alzheimer's disease neuroimaging initiative; Anti-Amyloid, treatment of asymptomatic Alzheimer's disease trial; CCCDTD4, 4th Canadian Consensus Conference

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial dysfunction and the inflammatory response

Keywords: AD، بیماری آلزایمر; 4-HNE, 4-hydroxy-2-nonenal; ∆ψm, mitochondrial membrane potential; AD, Alzheimer's disease; AP-1, activator protein-1; APC, antigen-presenting cell; ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain; ATP, adenosine triph

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Neural correlates of the DemTect in Alzheimer's disease and frontotemporal lobar degeneration – A combined MRI & FDG-PET study

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ANOVA, Analysis of variance; BA, Brodmann area; CDR, Clinical dementia rating scale; DARTEL, Diffeomorphic anatomical registration through exponentiated lie algebra; FDG-PET, F-18-fluorodeoxyglucose positron emission tomography; F

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Ferritin iron uptake and release in the presence of metals and metalloproteins: Chemical implications in the brain

Keywords: AD، بیماری آلزایمر; Ferritin; Iron metabolism; Neurochemistry6-OHDA, 6-hydroxydopamine; AD, Alzheimer's disease; Alpha(2)M, Alpha2-macroglobulin; ALS, amyotrophic lateral sclerosis; ApoB, apolipoprotein B; ARA, Arachidonic acid; Bypy, 2,2′-bipyridyl; CNS, central nervous sys

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

High quality drug screening by capillary electrophoresis: A review

Keywords: AD، بیماری آلزایمر; ACE, angiotensin I-converting enzyme; AChE, acetylcholinesterase; AD, Alzheimer's disease; ADP, adenosine diphosphate; AK, adenosine kinase; AMP, adenosine monophosphate; APES, aminopropyltriethoxysilane; APPI, atmospheric pressure photoionization; ATP, a

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Microglia during development and aging

Keywords: AD، بیماری آلزایمر; ATP, adenosine triphosphate; AD, Alzheimer's disease; Aβ, amyloid beta; BBB, blood brain barrier; Cl−, chloride; CD, cluster of differentiation; CR3, complement receptor 3; C1q, complement 1q; CNS, central nervous system; CX3CL1, fractalkine or neurotacti

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress

Keywords: AD، بیماری آلزایمر; AFG3L1, Human AFG3-like protein 1; ALLN, N-Acetyl-Leu-Leu-Nle-CHO; AD, Alzheimer's disease; Bcl-2, B-cell lymphoma 2; BOC, Boc-D(OMe)–FMK; CGNs, cerebellar granule neurons; CSF, cerebrospinal fluid; JNK, c-Jun NH(2)-terminal kinase; Drp1, dynamin-related

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

The effect of lead exposure on brain iron homeostasis and the expression of DMT1/FP1 in the brain in developing and aged rats

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; BLL, blood lead level; DMT1, divalent metal transporter 1; Fe, iron; FP1, ferroportin 1; HLG, high lead group (573 mg/L lead acetate × calculate by Pb2+); ID, iron-deficiency; LLG, low lead group (191 mg/L lead acetate × calculate

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Blood and plasma-based proteomic biomarker research in Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ApoA-I, apolipoprotein A-I; CNS, central nervous system; CSF, cerebrospinal fluid; ELISA, enzyme-linked immunosorbent assay; EMA, European Medicines Agency; ESI, electrospray ionization; F2-IsoPs, F2-isoprostanes; FDA, Food and Dr

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

Keywords: AD، بیماری آلزایمر; Phase II genes; Keap1/Nrf2/ARE; Inducers; Effectors; Acute neurological diseases; Neurodegenerative diseasesAβ, amyloid-beta; AA-MU, alternative activation phenotype; AD, Alzheimer's disease; AhR, aryl hydrocarbon receptor; ALCAR, acetyl-L-carnitine; ALS,

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenetic targeting of histone deacetylase: Therapeutic potential in Parkinson's disease?

Keywords: AD، بیماری آلزایمر; Parkinson's disease; Neurodegeneration; Epigenetics; Histone deacetylase; Histone deacetylase inhibitor; Neuroprotection6-OHDA, 6-hydroxydopamine; Ac, acetyl; Ac-Lys, acetyl-lysine; AD, Alzheimer's disease; ALS, Amylotrophic Lateral Sclerosis; BBB, blood

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's dise

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β; Aβs, Aβ peptides; AD, Alzheimer's disease; AβDPs, Aβ-degrading proteases; APP, Aβ precursor protein; BACE 1, β-site APP-cleaving enzyme 1; β-S, β-secretase; CaSR, calcium-sensing receptor; fAβ, fibrillated Aβ; γ-S, γ-secretase; GCH-1, GTP c

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

GDNF, NGF and BDNF as therapeutic options for neurodegeneration

Keywords: AD، بیماری آلزایمر; AAV2, adeno-associated viral vector; AD, Alzheimer's disease; ADAMs, a disintegrin and metalloprotease enzyme family; ALS, Amyotrophic lateral sclerosis; AICD, APP intracellular domain; apoE, apolipoprotein E; APP, amyloid precursor protein; BACE, beta-si

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2013 سفارش ترجمه

Reconsider Alzheimer's disease by the ‘calpain–cathepsin hypothesis’—A perspective review

Keywords: AD، بیماری آلزایمر; Aβ, amyloid β; AD, Alzheimer's disease; ALLN, N-acetyl-Leu-Leu- Nle-CHO; apoE, apolipoprotein E; APP, amyloid precursor protein; APPLon, APP containing the London mutant γ-secretase site sequence; APPSwe, APP containing the Swedish mutant β-secretase site

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2013 سفارش ترجمه

Meningeal and choroid plexus cells—Novel drug targets for CNS disorders

Keywords: AD، بیماری آلزایمر; Aβ, amyloid beta; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; AMP, adenosine monophosphate; APP, amyloid precursor protein; BMI, body mass index; CCL2, chemokine (C–C motif) ligand 2 (also known as MCP-1); CCR6, chemokine receptor 6; CCL2

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2013 سفارش ترجمه

Current status of chemokines in the adult CNS

Keywords: AD، بیماری آلزایمر; Aβ, β amyloid; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; APP, amyloid precursor protein; AVP, vasopressin; BBB, blood–brain barrier; CNS, central nervous system; CSF, cerebrospinal fluid; DOR, delta opioid receptor; ERK, extracellular s

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2013 سفارش ترجمه

Haplotypes across the human caveolin 1 gene upstream purine complex significantly alter gene expression: Implication in neurodegenerative disorders

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; CAV1, Caveolin 1; IRF, interferon‐regulatory factor; MS, Multiple sclerosis; PCR, Polymerase chain reaction; SNP, Single nucleotide polymorphism; STR, Short tandem repeatCaveolin 1; Upstream; Purine complex; Expression; Neurodegen

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Ibuprofen ameliorates protein aggregation and astrocytic gliosis, but not cognitive dysfunction, in a transgenic mouse expressing dementia with Lewy bodies-linked P123H β-synuclein

Keywords: AD، بیماری آلزایمر; PD, Parkinson's disease; AD, Alzheimer's disease; DLB, dementia with Lewy bodies; tg, transgenic; β-syn, β-synuclein; α-syn, α-synuclein; NSAIDs, nonsteroidal anti-inflammatory drugs; GFAP, glial fibrillary acidic protein; qPCR, quantitative polymerase ch

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Recent preclinical evidence advancing cell therapy for Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, amyloid precursor protein; BDNF, brain-derived neurotrophic factor; CD, cDNA; HGF, hepatocyte growth factor; NGF, neural growth factor; NSC, neural stem cell; SCF, stem cell factor; SDF-1, stromal cell-derived factor-1; VEGF,

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Mirror image phage display – Generating stable therapeutically and diagnostically active peptides with biotechnological means

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid-β; Dag, hepatitis delta antigen; HDV, hepatitis delta virus; HIV-1, human immunodeficiency virus type 1; NMR, nuclear magnetic resonance; SH3, Src homology 3; ThT, thioflavineMirror image phage display; d-enantiomeric

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Axonal transport and neurodegenerative disease: Can we see the elephant?

Keywords: AD، بیماری آلزایمر; HD, Huntington's Disease; AD, Alzheimer's Disease; APP, amyloid precursor protein; TGN, trans-golgi network; BACE, beta-secretaseAlzheimer's disease; Huntington's disease; Axonal transport; Kinesin; Dynein

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of yokukansan on behavioral and psychological symptoms of vascular dementia: An open-label trial

Keywords: AD، بیماری آلزایمر; VaD, vascular dementia; AD, Alzheimer's disease; BPSD, behavioral and psychological symptoms of dementia; EPS, extrapyramidal symptoms; ADL, activities of daily living; 3D-HPLC, three-dimensional high-performance liquid chromatography; NINDS-AIREN, Nation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

RNF11 modulates microglia activation through NF-κB signalling cascade

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; CNS, central nervous system; co-IP, coimmunoprecipitation; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IκBs, inhibitors of NF-κB; IP, immunoprecipitation; LPS, lipopolysaccharide; MCP-1, monocyte chemoattractant protein-1; PD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Amyloid oligomer detection by immobilized molecular chaperone

Keywords: AD، بیماری آلزایمر; Aβ, Amyloid β; AD, Alzheimer's disease; ADDL, Aβ-derived diffusible ligand; ELISA, enzyme-linked immunosorbent assay; LTP, long-term potentiation; MPC, 2-methacryloyloxyethyl phosphorylcholine; PFD, PrefoldinAggregation; Amyloid beta; Biosensors; Biosepar

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Cognitive activity, education and socioeconomic status as preventive factors for mild cognitive impairment and Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; CAS, cognitive activity score; CLA, cognitive leisure activities; MCI, mild cognitive impairment; SES, socioeconomic statusCognitive reserve; Cognitive activity; Education; Socioeconomic status; Alzheimer's disease; Mild cognitive

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Rapid and reliable quantitation of amino acids and myo-inositol in mouse brain by high performance liquid chromatography and tandem mass spectrometry

Keywords: AD، بیماری آلزایمر; LC–MS/MS, liquid chromatography–tandem mass spectrometry; HILIC, hydrophilic interaction liquid chromatography; MRM, multiple reaction monitoring; ACN, acetonitrile; MeOH, methanol; IS, internal standard; AD, Alzheimer's disease; PD, Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Coordination of zinc ions to the key proteins of neurodegenerative diseases: Aβ, APP, α-synuclein and PrP

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; PD, Parkinson's disease; TSE, transferable spongiform encephalitis; APP, amyloid-β precursor protein; Aβ, amyloid-β peptide; PrP, prion protein; CuBD, copper binding domainZinc; Alzheimer's disease; Parkinson disease; Prion; Amylo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The use of PIB-PET as a dual pathological and functional biomarker in AD

Keywords: AD، بیماری آلزایمر; PET, Positron emission tomography; AD, Alzheimer's disease; CBF, cerebral blood flow; FDG, [18F]-2-deoxy-d-glucose; MCI, Mild cognitive impairments; HC, Healthy controls; MMSE, Mini-Mental State Examination; PIB, N-methyl [11C] 2-(4′-methylaminophenyl)-6-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Frontal dysfunctions of ALS-PBP patients in relation to their bulbar symptoms and rCBF decline

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; ALSFRS-R, ALS functional rating scale—revised; AR, androgen receptor; SBMA, Spinal and bulbar muscular atrophy; CDR, Clinical Dementia Rating; eZIS, easy Z-score imaging system; FAB, frontal ass

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Presenilin-2 polymorphisms and risk of sporadic AD: Evidence from a meta-analysis

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APOE ε4, ε4 allele of the apolipoprotein; CI, confidence interval; DSM, the Diagnostic and Statistical Manual of Mental Disorders; PSEN2, presenilin 2; OR, odds ratios; HWE, Hardy–Weinberg equilibrium; MMSE, Mini-Mental State Exam

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders

Keywords: AD، بیماری آلزایمر; MPP+, 1-methyl-4-phenylpyridinium; 4-PBA, 4-phenylbutyrate; AD, Alzheimer's disease; Aβ, amyloid-beta peptide; APP, β-amyloid precursor protein; HAT, histone acetyl transferase; HDACs, histone deacetylases; HD, Huntington's disease; PD, Parkinson's diseas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Association between apolipoprotein E gene polymorphism and the risk of multiple sclerosis: A meta-analysis of 6977 subjects

Keywords: AD، بیماری آلزایمر; ApoE, apolipoprotein E; MS, multiple sclerosis; AD, Alzheimer's disease; PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-analyses; OR, odds ratio; CI, confidence interval; NOS, Newcastle–Ottawa Scale; HWE, Hardy–Weinberg equilibriumMulti

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

In vitro screening on amyloid precursor protein modulation of plants used in Ayurvedic and Traditional Chinese medicine for memory improvement

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, β-amyloid peptide; APP, amyloid-β precursor protein; ADAMs, a disintegrin and metalloproteinases; sAPP, α soluble APP; AICD, APP intracellular domain; BACE1, beta-site APP cleaving enzyme1; sAPPβ, β soluble APP; BBB, blood–bra

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Meta-analysis on association between the ATP-binding cassette transporter A1 gene (ABCA1) and Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ABCA1, ATP-binding cassette transporter A1; Aβ, Amyloid beta; CI, Confidence interval; EOAD, Early onset Alzheimer's disease; LOAD, Late onset Alzheimer's disease; HWE, Hardy–Weinberg equilibrium; OR, Odds ratioAlzheimer's disease

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Thrombospondins as key regulators of synaptogenesis in the central nervous system

Keywords: AD، بیماری آلزایمر; ACM, astrocyte conditioned media; AD, Alzheimer's disease; AMPA, 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid; CNS, central nervous system; CRT, calreticulin; DS, Down's syndrome; ECM, extracellular matrix; EGF, epidermal growth factor; EM, el

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Glutamate receptors in preclinical research on Alzheimer's disease: Update on recent advances

Keywords: AD، بیماری آلزایمر; Aβ, amyloid beta; AD, Alzheimer's disease; hAPP, human amyloid precursor protein; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; BDNF, brain-derived neurotrophic factor; CaMKII, calcium/calmodulin-dependent protein kinase II; EphB2, ephrin type-B

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Nuclear signalling by membrane protein intracellular domains: The AICD enigma

Keywords: AD، بیماری آلزایمر; Aβ, amyloid β-peptide; AD, Alzheimer's disease; ADAM, a disintegrin and metalloprotease; AICD, APP intracellular domain; APP, amyloid precursor protein; GSAP, γ-secretase activating protein; HDAC, histone deacetylase; IDE, insulin-degrading enzyme; KPI, K

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of PKA attenuates memory deficits induced by β-amyloid (1–42), and decreases oxidative stress and NF-κB transcription factors

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid β; PKA, protein kinase A; NFκB, nuclear factor-κB; γ-GCS, glutamylcysteine synthetase; HO-1, hemeoxygenase-1; GSH, glutathione; SOD, superoxide dismutase; MAPK, mitogen-activated protein kinase; MWM, Morris water maze;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Novel bis-(−)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid-β; AChE, acetylcholinesterase; AChEIs, acetylcholinesterase inhibitors; ADME, absorption, distribution, metabolism and excretion; ROS, reactive oxygen species; ACh, acetylcholine; MEP, meptazinol; LAH, lithium aluminum

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه