دانلود مقالات ISI درباره AD، بیماری آلزایمر + ترجمه فارسی

The art of building multifunctional metal-binding agents from basic molecular scaffolds for the potential application in neurodegenerative diseases

Keywords: AD، بیماری آلزایمر; 6-OHDA, 6-hydroxydopamine; 8HQ, 8-hydroxyquinoline; Aβ, amyloid β peptide; α-syn, α-synuclein protein; ACh, acetylcholine; AChE, acetylcholinesterase; AD, Alzheimer's disease; BBB, blood–brain barrier; clogP, calculated octanol–water partition coefficient

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2012 سفارش ترجمه

Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders

Keywords: AD، بیماری آلزایمر; AAADC, aromatic amino acid decarboxylase, also DOPA decarboxylase; AD, Alzheimer's disease; ADHD, attention deficit/hyperactivity disorder; BBB, blood–brain barrier; CAG, cytosine-adenine-guanine; CB1R, cannabinoid type 1 (central) receptor; CBF, cerebral

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2012 سفارش ترجمه

G protein-coupled receptor kinases: More than just kinases and not only for GPCRs

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; β2AR, β2-adrenergic receptor; CDK2, cyclin-dependent kinase 2; GAP, GTPase activating proteins; GIRK, G protein-coupled potassium channels; GIT, GRK interacting proteins; GPCR, G protein-coupled receptor; GRK, G protein-coupled re

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2012 سفارش ترجمه

The role of genetics for biomarker development in neurodegeneration

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ADNI, Alzheimer's Disease Neuroimaging Initiative; ALS, amyotrophic lateral sclerosis; DIAN, Dominantly Inherited Alzheimer Network; FTD, frontotemporal dementia; GWAS, genome-wide association studies; MCI, mild cognitive impairme

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Neuroprotective effect of Jatrorrhizine on hydrogen peroxide-induced cell injury and its potential mechanisms in PC12 cells

Keywords: AD، بیماری آلزایمر; Jat, Jatrorrhizine; H2O2, hydrogen peroxide; PC12, PC12 rat pheochromocytoma; AD, Alzheimer's disease; CCK-8, Cell Counting Kit-8; ROS, reactive oxygen species; SOD, superoxide dismutase; HO-1, heme oxygenase-1; MDA, malondialdehyde; MMP, mitochondrial me

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Angiotensin II does not directly affect Aβ secretion or β-/γ-secretase activity via activation of angiotensin II type 1 receptor

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Ang II, angiotensin II; AT1R, angiotensin II type 1 receptor; Aβ, amyloid-β; APP, amyloid precursor protein; PS1, presenilin 1; RAS, renin-angiotensin system; ACE, angiotensin-converting enzyme; ARBs, angiotensin II receptor block

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits

Keywords: AD، بیماری آلزایمر; AChE, Acetylcholinesterase enzyme; AD, Alzheimer's disease; ATCI, Acetylthiocholine iodide; BChE, Butyrylcholinesterase; BTCI, Butyrylthiocholine iodide; DTNB = 5, 5-dithiobis 2-nitrobenzoic acidAcetylcholinesterase; Butyrylcholinesterase; Anethole; Illic

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Effects of sex hormones on Alzheimer's disease-associated β-amyloid oligomer formation in vitro

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid β-protein; E1, estrone; E2, estradiol; E3, estriol; AND, androstenedione; TES, testosterone; PICUP, photo-induced cross-linking of unmodified proteins; GST, glutathione S-transferase; CSF, cerebrospinal fluidAlzheimer'

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Amyloid in neurodegenerative diseases: Friend or foe?

Keywords: AD، بیماری آلزایمر; htt, huntingtin; HD, Huntington's disease; AD, Alzheimer's disease; CC, coiled-coil; (polyQ), polyglutamine; IB, inclusion body; APP, amyloid precursor protein; FRET, fluorescence resonance energy transfer; LTP, long-term potentiation; PQC, protein qualit

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Sensing change: The emerging role of calcium sensors in neuronal disease

Keywords: AD، بیماری آلزایمر; AC, adenylate cyclase; AD, Alzheimer's disease; AMPAR, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; AP2, adaptor protein 2; APP, amyloid precursor protein; CaBP, calcium binding protein; Ca2+/CaMKII, Ca2+/CaM-dependent protein kinase II;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Normalization of gene expression using SYBR green qPCR: A case for paraoxonase 1 and 2 in Alzheimer's disease brains

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Cq, quantification cycle; ERG, endogenous reference gene; HDL, high-density lipoprotein; HKG, housekeeping gene; LDL, low-density lipoprotein; PON, paraoxonase; qPCR, quantitative PCR; RIN, RNA integrity number; Tm, melting temper

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Spectroscopic studies on the irreversible heat-induced structural transition of Pin1

Keywords: AD، بیماری آلزایمر; PPIase, peptidyl–prolyl cis/trans isomerase; AD, Alzheimer's disease; ANS, 8-anilino-1-naphthalenesulfonic acid; RLS, resonance light scattering; FTIR, Fourier transform infrared spectra; CD, circular dichroism; λex, excitation wavelength; λmax, maximum e

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Effects of streptozotocin-induced diabetes on tau phosphorylation in the rat brain

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Akt, protein kinase B; DM, diabetes mellitus; GSK-3, glycogen synthase kinase-3; PHF, paired helical filament; PP-2A, protein phosphatase-2A; STZ, streptozotocinHyperglycemia; Tau hyperphosphorylation; Glycogen synthase kinase-3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Borobudur revisited: Soy consumption may be associated with better recall in younger, but not in older, rural Indonesian elderly

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; E2, estradiol; DR, delayed recall; IR, immediate recall; HT, hormone therapy; HVLT, Hopkins Verbal Learning Test; MMSE, Mini-Mental Status Examination; SD, standard deviation; SES, socioeconomic status; WHIMS, Women's Health Initi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Distribution patterns of cannabinoid CB1 receptors in the hippocampus of APPswe/PS1ΔE9 double transgenic mice

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's Disease; Aβ, amyloid beta; APP, amyloid precursor protein; AEA, Arachidonylethanolamide; 2-AG, 2-arachidonylglycerol; CB1, cannabinoid receptor 1; CB2, cannabinoid receptor 2; CNS, central nervous system; dtg, double transgenic; GFAP, glia

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Triptolide and its expanding multiple pharmacological functions

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ADAM10, metalloproteinase 10; ADPKD, autonomic dominant polycystic kidney disease; AML, acute myeloid leukemia; ATC, anaplastic thyroid carcinoma; CBP, CREB-binding protein; C/EBPα, CCAAT/enhancer-binding protein-α; CIA, collagen-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Prevention trials in Alzheimer's disease: An EU-US task force report

Keywords: AD، بیماری آلزایمر; Aβ42, amyloid beta 1–42 peptide; AD, Alzheimer's disease; ADNI, Alzheimer's Disease Neuroimaging Initiative; ApoE, apolipoprotein E; CDR, clinical dementia rating; CRO, clinical research organization; CSF, cerebrospinal fluid; DTI, diffusion tensor imagin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Chemical characterization of pro-inflammatory amyloid-beta peptides in human atherosclerotic lesions and platelets

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-beta; AD, Alzheimer's disease; ApoE, apolipoprotein E; APP, amyloid precursor protein; AVD, atherosclerotic vascular disease; BBB, blood–brain barrier; CAA, cerebral amyloid angiopathy; FPLC, fast protein liquid chromatography; GDFA, glass-dis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Neuroprotective effects of Mycoplasma hyorhinis against amyloid-β-peptide toxicity in SH-SY5Y human neuroblastoma cells are mediated by calpastatin upregulation in the mycoplasma-infected cells

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β-peptide; AD, Alzheimer's disease; APP, the amyloid precursor protein; BSA, bovine serum albumin; DTT, dithiothreitol; FCS, fetal calf serum; GM, growth medium; IB, immunoblotting; NDMh, neuroblastoma-derived Mycoplasma hyorhinis; PARP, poly(

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Amyloid beta-HSP60 peptide conjugate vaccine treats a mouse model of Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, amyloid precursor protein; CFA, complete Freund's adjuvant; HSP, heat shock protein; HLA, human leukocyte antigen; IFA, incomplete Freund's adjuvant; IFN-γ, interferon-gamma; IL, interleukin; IHC, immunohistochemistry; Ig, im

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage

Keywords: AD، بیماری آلزایمر; AβPP, amyloid beta precursor protein; AD, Alzheimer's disease; ATP, adenosine triphosphate; BrdU, 5-bromo-2-deoxyuridine; Drp1, dynamin related protein 1; Fis1, mitochondrial fission 1Primary neuron; Alzheimer's disease; Mitochondrial DNA synthesis; 5-Bro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Mesenchymal stem cells rescue the Alzheimer's disease cell model from cell death induced by misfolded truncated tau

Keywords: AD، بیماری آلزایمر; mesenchymal stem cells; Alzheimer's disease; truncated tau proteinAB, alamar blue; AD, Alzheimer's disease; AT tau, human misfolded truncated tau protein; BDNF, brain-derived neurotrophic factor; MSCs, mesenchymal stem cells; RA, retinoic acid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of matrix metalloproteinase 2 by oligomeric amyloid β protein

Keywords: AD، بیماری آلزایمر; Amyloid β; Matrix metalloproteinase; Primary astrocyte; Oligomeric AβAβ, beta amyloid; MMP, matrix metalloproteinase; AD, Alzheimer's disease; ECM, extracellular matrix

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

miR-29c regulates BACE1 protein expression

Keywords: AD، بیماری آلزایمر; miRNAs, microRNAs; AD, Alzheimer's disease; 3′ UTR, 3′-untranslated regions; BACE1, beta-site APP-cleaving enzyme 1; Aβ, Amyloid-betamiR-29c; Alzheimer's disease; BACE1 protein; MicroRNAs; APPswe/PSΔE9 mouse

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; B12H, bis(12)-hupyridone; CREB, cAMP response element-binding protein; dbcAMP, dibutyryl cAMP; ERK, extracellular signal-regulated kinase; HA, huperzine A; NGF, nerve growth factor; MEK, mitogen-activated protein kinase kinase; ML

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice

Keywords: AD، بیماری آلزایمر; ACh, acetylcholine; AChE, acetylcholinesterase; APP, amyloid protein precursor; ANOVA, analysis of variance; Aβ, amyloid beta; AD, Alzheimer's disease; BuCh, butyrylcholine; BuChE, butyrylcholinesterase; ChEIs, cholinesterase inhibitors; ERK, extracellula

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Curcumin has bright prospects for the treatment of multiple sclerosis

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; BBB, blood–brain barrier; CNS, central nervous system; EAE, experimental autoimmune encephalomyelitis; IL-17, interleukin-17; MLC, myosin light chain; MS, multiple sclerosisAutoimmune disease; Curcumin; Multiple sclerosis; Experim

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Curcumin enhances neuronal survival in N-methyl-d-aspartic acid toxicity by inducing RANTES expression in astrocytes via PI-3K and MAPK signaling pathways

Keywords: AD، بیماری آلزایمر; ACM, astrocyte-conditioned medium; AD, Alzheimer's disease; ANOVA, one-way analysis of variance; CNS, central nervous system; Ct, threshold cycle; DIV, days in vitro; DMEM, Dulbecco's modified Eagle's medium; FBS, fetal bovine serum; GPCRs, guanine-protei

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

An SRp75/hnRNPG complex interacting with hnRNPE2 regulates the 5′ splice site of tau exon 10, whose misregulation causes frontotemporal dementia

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; DM1, myotonic dystrophy type 1; DS, Down syndrome; (k)bp, (kilo)base pairs; FTDP-17, frontotemporal dementia with Parkinsonism; hnRNP, heterogeneous nuclear ribonucleoprotein; IP, immunoprecipitation; ISS, intronic splicing silenc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Recent developments of functional magnetic resonance imaging research for drug development in Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; DMN, default mode network; DTI, diffusion tensor imaging; EMEA, European Medicines Agency; FDA, Food and Drug Administration; fMRI, functional magnetic resonance imaging; HC, healthy controls; MCI, Mild Cognitive ImpairmentMild Co

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALP, autophagy-lysosomal pathway; AMC, 7-amino-4-methylcoumarin; BrdU, bromodeoxyuridine; ERK, extracellular-signal-regulated kinase; GSK-3, glycogen synthase kinase 3; GSH, glutathione; HSP, heat shock proteins; HD, Huntington's

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

A novel mechanism of non-Aβ component of Alzheimer's disease amyloid (NAC) neurotoxicity. Interplay between p53 protein and cyclin-dependent kinase 5 (Cdk5)

Keywords: AD، بیماری آلزایمر; NAC, non-Aβ component of Alzheimer's disease; AD, Alzheimer's disease; APP, amyloid precursor protein; ASN, α-synuclein; Aβ, amyloid β; AV, autophagic vacuole; AVL, autolysosome vacuole; Bax, proapoptotic protein; BSN, β-synuclein; Cdk5, cyclin-dependent

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Age-related autophagy alterations in the brain of senescence accelerated mouse prone 8 (SAMP8) mice

Keywords: AD، بیماری آلزایمر; SAMP8, Senescence accelerated mouse prone 8; AD, Alzheimer's disease; PD, Parkinson's disease; UPS, Ubiquitin–proteasomal system; AVs, Autophagic vacuoles; LC3, Microtubule-associated-protein-light-chain-3; MCI, Mild cognitive impairment; Aβ, Amyloid-β; M

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; TNF-α, tumor necrosis factor-α; Aβ, amyloid β-peptide; ICV, intracerebroventricularAlzheimer's disease; Tumor necrosis factor-α; Amyloid plaque; Tau phosphorylation; CD11c-positive dendritic-like cell

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Clinicopathological study of diffuse neurofibrillary tangles with calcification: With special reference to TDP-43 proteinopathy and alpha-synucleinopathy

Keywords: AD، بیماری آلزایمر; aSyn, alpha-synuclein; AD, Alzheimer's disease; AGD, argyrophilic grain disease; ALS, amyotrophic lateral sclerosis; DLB, Dementia with Lewy bodies; DN, dystrophic neurite; DNTC, diffuse neurofibrillary tangles with calcification; FTLD, frontotemporal lob

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; CA, Cornu Ammonis; FFPE, formalin-fixed paraffin-embedded; LCM, laser capture microdissection; MMSE, mini-mental status exam; NFT, neurofibrillary tangleCognitive impairment; Aging; Neurodegeneration; Neurofibrillary tangles; Myel

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

ERK pathway activation is required for amyloid-β1–40-induced neurotoxicity of THP-1 human monocytes towards SK-N-SH neuroblastoma

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ1–40, amyloid β1–40; BBB, blood–brain barrier; IL-1β, interleukin-1β; IL-8, interleukin-8; TNF-α, tumor necrosis factor-α; COX-2, cyclooxygenase-2; iNOS, inducible nitric oxide synthase; NO, nitric oxide; PTK, protein tyrosine k

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

β-Amyloid triggers ALS-associated TDP-43 pathology in AD models

Keywords: AD، بیماری آلزایمر; PD, Parkinson's disease; AD, Alzheimer's disease; FTLD-U, fronto-temporal lobar dementia with ubiquitin-positive inclusions; ALS, amyotrophic lateral sclerosis; MND, motor neuron disease; TDP-43, Tar-DNA binding protein-43; Aβ, β-amyloid; CK1, casein kina

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Alzheimer's disease: Effects of β-amyloid on mitochondria

Keywords: AD، بیماری آلزایمر; 4-HNE, 4-Hydroxy-2-nonenal; ABAD, β-amyloid binding alcohol dehydrogenase; AD, Alzheimer's disease; APP, Amyloid Precursor Protein; apoE, apolipoprotein E; LRP1, LDL receptor-related protein 1; AIF, apoptosis inducing factor; Drp-1, dynamin-related protei

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting the neurovascular unit for treatment of neurological disorders

Keywords: AD، بیماری آلزایمر; Blood-brain barrier; Alzheimer's disease; Stroke; Astrocyte; Drug deliveryCNS, central nervous system; BBB, blood-brain barrier; NVU, neurovascular unit; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; MS, multiple sclerosis; Da, Dalton; SNpc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment

Keywords: AD، بیماری آلزایمر; AChE, acetylcholinesterase; aCSF, artificial cerebrospinal fluid; AD, Alzheimer's disease; Aβ, amyloid beta; BSA, bovine serum albumin; DCF-DA, 2′, 7′-dichlorofluorescin-diacetate; DTNB, 5,5′-dithiobis (2-nitrobenzoic acid); FURA/2AM, Fura-2-acetoxymethyl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The “A Disintegrin And Metalloproteases” ADAM10 and ADAM17: Novel drug targets with therapeutic potential?

Keywords: AD، بیماری آلزایمر; ADAM, A Disintegrin And Metalloproteinase; AD, Alzheimer's disease; APP, Amyloid Precursor Protein; AR, Amphiregulin; BTC, Betacellulin; CXCL, CXC, chemokine ligand; EGF, Epidermal growth factor; EGFR, EGF receptor; EPR, Epiregulin; HB-EGF, Heparin-bindin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The amyloid precursor protein intracellular domain alters gene expression and induces neuron-specific apoptosis

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; AICD, the intracellular domain of APP; APP, amyloid precursor protein; cAMP, cyclic adenosine 3′5′-monophosphate; GO, gene ontology; NICD, the intracellular domain of Notch; RA, all-trans-retinoic acid; RT-PCR, reverse transcripti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Insulin-like growth factor-I mediates neuroprotection in proteasome inhibition-induced cytotoxicity in SH-SY5Y cells

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's Disease; CT-L, Chymotrypsin-like; DMSO, Dimethyl sulfoxide; ECL, Chemiluminescences; IGF-1, Insulin-like growth factor-1; MEM, Minimum essential medium; MTT, [3-(4,5-dimethylthiazol-2-yl)-2,5-Diphenyl etrazolium bromide]; PARP, poly adenos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Caffeine induces beneficial changes in PKA signaling and JNK and ERK activities in the striatum and cortex of Alzheimer's transgenic mice

Keywords: AD، بیماری آلزایمر; Aβ, amyloid beta; AD, Alzheimer's disease; ANOVA, Analysis of Variance; APPswe, amyloid precursor protein, Swedish mutation; cAMP, cyclic adenosine monophosphate; CREB, cAMP response element-binding; ELISA, enzyme-linked immunosorbent assay; ERK, extracel

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration

Keywords: AD، بیماری آلزایمر; PD, Parkinson's disease; AD, Alzheimer's disease; CBP, CREB-binding protein; HAT, histone acetyl transferase; HDAC, histone deacetylase; PKCδ, protein kinase C delta; paraquat, 1,1′-dimethyl-4,4′-bipyridium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrid

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Protein aggregate spreading in neurodegenerative diseases: Problems and perspectives

Keywords: AD، بیماری آلزایمر; CJD, Creutzfeldt–Jakob disease; AD, Alzheimer's disease; PD, Parkinson's disease; HD, Huntington's disease; Aβ, amyloid-β; polyQ, polyglutamine; CNS, central nervous system; NFTs, neurofibrillary tangles; NTs, neuropil threads; APP, amyloid precursor prot

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Brain aging, Alzheimer's disease, and mitochondria

Keywords: AD، بیماری آلزایمر; AACD, age-associated cognitive decline; AAMI, age-associated memory impairment; Aβ, beta amyloid; AD, Alzheimer's disease; APP, amyloid precursor protein; BACE, beta secretase; COX, cytochrome oxidase; CSF, cerebrospinal fluid; cybrid, cytoplasmic hybrid;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β peptide; AβDIP, Aβ-related death-inducing protein; AβID, Aβ interacting domain; AD, Alzheimer's disease; AICD, APP protein intracellular domain fragment; APP, Aβ-precursor protein; APP, Aβ-precursor protein gene; ASCL1, achaete–scute complex

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Dissociating behavioral disorders in early dementia—An FDG-PET study

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ANOVA, Analysis of variance; BA, Brodmann area; BADS, Behavioral Assessment of the Dysexecutive Syndrome; CDR, Clinical Dementia Rating Scale; FDG-PET, [18F] fluorodeoxyglucose positron emission tomography; FTD, Frontotemporal dem

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه