دانلود مقالات ISI درباره آلک + ترجمه فارسی

Synthesis and evaluation of novel 2,4-diaminopyrimidines bearing bicyclic aminobenzazepines for anaplastic lymphoma kinase (ALK) inhibitor

Keywords: آلک; Cancer; ALK; 2,4-Diaminopyrimidine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

ALK-FISH borderline cases in non-small cell lung cancer: Implications for diagnostics and clinical decision making

Keywords: آلک; ADC; adenocarcinoma; ADSC; adenosquamous carcinoma; ALK; anaplastic lymphoma kinase; BL; borderline; CNG; copy number gain; EMA; European Medicines Agency; FDA; Food and Drug Administration; FISH; fluorescence in-situ hybridization; FS; fused signals; FN;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Regulatory effects of fibroblast growth factor-8 and tumor necrosis factor-α on osteoblast marker expression induced by bone morphogenetic protein-2

Keywords: آلک; ALK; activin receptor-like kinase; ActRII; activin type-II receptor; ALP; alkaline phosphatase; BMP; bone morphogenetic protein; BMPRII; BMP type-II receptor; ERK; extracellular signal-regulated kinase; FGF; fibroblast growth factor; FGFR; FGF receptor; M

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Résistances aux thérapeutiques ciblées et stratégies des lignes ultérieures dans les CBNPC métastatiques

Keywords: آلک; ALK; EGFR; Inhibiteur de tyrosine-kinase; Résistance primaire; Résistance secondaire; ROS1; Acquired resistance; ALK; EGFR; Primary resistance; ROS1; Tyrosine kinase inhibitors;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and anticancer activities of ceritinib analogs modified in the terminal piperidine ring

Keywords: آلک; ALK; Ceritinib analogs; Anticancer; Synthesis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Comparison of Methods in the Detection of ALK and ROS1 Rearrangements in Lung Cancer

Keywords: آلک; ALK; ROS1; Non-small-cell lung cancer; Fluorescence in situ hybridization; Immunohistochemistry; Chromogenic in situ hybridization;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

ALK Testing in Lung Adenocarcinoma: Technical Aspects to Improve FISH Evaluation in Daily Practice

Keywords: آلک; ALK; Fluorescence in situ hybridization; ALK inhibitor; Lung cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Synergistic effects of crizotinib and radiotherapy in experimental EML4-ALK fusion positive lung cancer

Keywords: آلک; Crizotinib; Radiotherapy; Non-small cell lung cancer; ALK;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ShcC proteins: Brain aging and beyond

Keywords: آلک; ShcC adaptor proteins; Signaling; Aging; Brain ischemia; Brain tumors; Immunity; Aβ; beta-amyloid; AD; Alzheimer's disease; Akt; protein kinase B (PKB); ALK; anaplastic lymphoma kinase (receptor tyrosine kinase); APP; alpha-amyloid precursor protein; ARD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Future options for ALK-positive non-small cell lung cancer

Keywords: آلک; Alectinib; ALK; ALK-TKI; CNS metastases; Ceritinib; Crizotinib; Non-small cell lung cancer; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Profiling of Oncogenic Driver Events in Lung Adenocarcinoma Revealed MET Mutation as Independent Prognostic Factor

Keywords: آلک; Lung cancer; EGFR; KRAS; ALK; HER2; BRAF; MET; ROS1; RIT1; TTF-1 lung adenocarcinoma; NRAS; Driver mutations; Oncogenic driver mutation; East Asian lung cancer; MET amplification; Targeted therapy; Genetic marker; Biomarker; Molecular classification lung

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibiteurs de ALK de 2e génération dans le cancer bronchique non à petites cellules : revue de la littérature

Keywords: آلک; Cancer bronchique non à petites cellules; ALK; Crizotinib; Mécanismes de résistance; Inhibiteurs de ALK; NSCLC; ALK; Crizotinib; ALK inhibitors; Resistance mechanisms;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Expression of helper T cell master regulators in inflammatory dermatoses and primary cutaneous T-cell lymphomas: Diagnostic implications

Keywords: آلک; T-bet; GATA-3; cutaneous lymphoma; mycosis fungoides; Sezary syndrome; anaplastic large cell lymphoma; T helper cell; ALK; anaplastic lymphoma kinase; CTCL; cutaneous T-cell lymphoma; C-ALCL; cutaneous anaplastic large cell lymphoma; H&E; hematoxylin and

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewPharmacogenomics and targeted therapy of cancer: Focusing on non-small cell lung cancer

Keywords: آلک; ALDH; aldehyde dehydrogenase; ALK; anaplastic lymphoma kinase; BRAF; v-Raf murine sarcoma viral oncogene homolog B1; CSC; cancer stem cell; EGFR; epidermal growth factor receptor; EGFR-TKIs; EGFR tyrosine kinase inhibitors; EGFRvIII; EGFR variant III; EML

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Beyond EGFR and ALK inhibition: Unravelling and exploiting novel genetic alterations in advanced non small-cell lung cancer

Keywords: آلک; Non-small cell lung cancer; Oncogenic drivers; EGFR; ALK; KRA; BRAF; HER2; PI3KCA; DDR2; ROS1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Overexpression of activin-A and -B in malignant mesothelioma - Attenuated Smad3 signaling responses and ERK activation promote cell migration and invasive growth

Keywords: آلک; ACVR2; type 2 activin receptor; ALK; activin receptor-like kinase; ERK; extracellular signal-regulated kinase; FST; follistatin; FSTL3; follistatin like 3; JNK; c-Jun N-terminal kinase; TGF-β; transforming growth factor-β; Mesothelioma; Activin; Invasiv

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Production of biogas and performance evaluation of existing treatment processes in palm oil mill effluent (POME)

Keywords: آلک; Renewable biogas; POME; Anaerobic; Aerobic; Physiochemical treatment; Upflow anaerobic sludge-fixed film (UASFF) reactor; Membrane separation treatment; AD; anaerobic digestion; AF; anaerobic filter; AFBR; anaerobic fluidized bed reactor; ABR; anaerobic b

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Growth and differentiation factor 11 (GDF11): Functions in the regulation of erythropoiesis and cardiac regeneration

Keywords: آلک; GDF11; Erythropoiesis; Cardiac regeneration; Act; activin; ActR; activin receptor type; ALK; activin receptor-like kinase; BMP; bone morphogenetic protein; BMPR; BMP receptor; CCL11; chemokine (C-C motif) ligand 11; CHF; coronary heart failure; EPO; ery

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2)

Keywords: آلک; ABC; ATP-binding cassette; ALK; anaplastic lymphoma kinase; AUC; area under the plasma concentration-time curve; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; Cmax; maximum drug concentration in plasma; EML4; echinoderm microtubule-ass

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended

Keywords: آلک; ALK; Lung cancer; Immunohistochemistry; 5A4; D5F3; FISH;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

TGF-β superfamily signaling in testis formation and early male germline development

Keywords: آلک; ALK; activin receptor-like kinase; BMPs; bone morphogenetic proteins; Co-Smads; common-mediator Smads; FGF; fibroblast growth factor; GDFs; growth differentiation factors; I-Smads; inhibitory Smads; PGCs; primordial germ cells; R-Smads; receptor-regulated

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2015 سفارش ترجمه

Parallel screening for ALK, MET and ROS1 alterations in non-small cell lung cancer with implications for daily routine testing

Keywords: آلک; Non-small cell lung cancer; MET; ALK; ROS1; FISH; IHC; Targeted therapy; Predictive biomarkers;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

A Novel Fusion of TPR and ALK in Lung Adenocarcinoma

Keywords: آلک; Lung cancer; ALK; TPR; Translocation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Leukemic Phase of ALK+ Anaplastic Large-Cell Lymphoma, Small-Cell Variant: Clinicopathologic Pitfalls of a Rare Entity

Keywords: آلک; ALK; Anaplastic large-cell lymphoma; Leukemic phase; Small-cell variant;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Concomitant EGFR mutation and ALK rearrangement in lung adenocarcinoma is more frequent than expected: Report of a case and review of the literature with demonstration of genes alteration into the same tumor cells

Keywords: آلک; Lung; Adenocarcinoma; EGFR; ALK; FISH; Immunohistochemistry; NSCLC;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Assessment of ALK Status by FISH on 1000 Spanish Non-Small Cell Lung Cancer Patients

Keywords: آلک; ALK; FISH; Non-small cell lung cancer; Biopsy; Cytology

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

EGFR mutational genotyping of liquid based cytology samples obtained via fine needle aspiration (FNA) at endobronchial ultrasound of non-small cell lung cancer (NSCLC)

Keywords: آلک; Epidermal growth factor receptor; Non-small cell lung carcinoma; Endobronchial ultrasound guided fine needle aspiration; Fine needle aspiration; Lung cancer; Targeted therapy; ALK; anaplastic lymphoma kinase; ASPCR; allele specific polymerase chain reacti

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

A Comparison of Immunohistochemical Assays and FISH in Detecting the ALK Translocation in Diagnostic Histological and Cytological Lung Tumor Material

Keywords: آلک; Pulmonary adenocarcinoma; ALK; Immunohistochemistry; Fluorescence in situ hybridization; Crizotinib;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of Axl improves the targeted therapy against ALK-mutated neuroblastoma

Keywords: آلک; Neuroblastoma; ALK; Targeted therapy; Axl; Small-molecule inhibitor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

RANBP2-ALK fusion combined with monosomy 7 in acute myelomonocytic leukemia

Keywords: آلک; RANBP2; ALK; fusion gene; monosomy 7; acute myelomonocytic leukemia

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Clinical Outcome With Platinum-Based Chemotherapy in Patients With Advanced Nonsquamous EGFR Wild-Type Non–Small-Cell Lung Cancer Segregated According to KRAS Mutation Status

Keywords: آلک; ALK; EGFR; KRAS; Non–small-cell lung cancer; Platinum-based chemotherapy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

ReviewDiagnosis and Predictive Molecular Analysis of Non-Small-Cell Lung Cancer in the Africa-Middle East Region: Challenges and Strategies for Improvement

Keywords: آلک; Adenocarcinoma; ALK; Biomarker; EGFR; Molecular testing;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Melatonin counteracts BMP-6 regulation of steroidogenesis by rat granulosa cells

Keywords: آلک; ALK; activin receptor-like kinase; ActRI; activin type-I receptor; ActRII; activin type-II receptor; BMP; bone morphogenetic protein; BMPRI; BMP type-I receptor; BMPRII; BMP type-II receptor; FSH; follicle-stimulating hormone; FSHR; FSH receptor; GDF; gro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Selective ALK inhibitor alectinib with potent antitumor activity in models of crizotinib resistance

Keywords: آلک; NSCLC; ALK; ALK inhibitor; Drug resistance; Alectinib; Xenograft model

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The molecular genetic profile of neuroblastoma

Keywords: آلک; ALK; ATRX; expression array; genomic array; miRNA; MYCN; neuroblastoma; 1p; ploidy; 17q

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A Novel Mechanism of EML4-ALK Rearrangement Mediated by Chromothripsis in a Patient-Derived Cell Line

Keywords: آلک; ALK; Lung cancer; Chromosomal rearrangement; Chromothripsis; ALK inhibitor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Roles of TGF-β family signals in the fate determination of pluripotent stem cells

Keywords: آلک; ALK; activin receptor-like kinase; BMPs; bone morphogenetic proteins; Bra; Brachyury; Co-Smads; common-mediator Smads; Dusp9; dual specificity phosphatase 9; EBs; embryonic bodies; EMT; epithelial to mesenchymal transition; ES; embryonic stem; FGF; fibrob

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Immunohistochemical screening and fluorescence in situ hybridization confirmation of ALK translocation in lung adenocarcinoma and its clinicopathological significance: a single-center large-scale investigation of Chinese patients

Keywords: آلک; Lung adenocarcinoma; Anaplastic lymphoma kinase; ALK; Translocation; FISH

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

From mice to men: GEMMs as trial patients for new NSCLC therapies

Keywords: آلک; AdCre; adenovirus Cre recombinase; ALK; anaplastic lymphoma kinase; ANGPTL3; angiopoietin-like 3; Ccsp; Clara cell secretory protein; GEMMs; genetically engineered mouse models; HSP; heat shock family; IN; intranasal; LentiCre; lentivirus Cre recombinase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of conserved and novel microRNAs in Manduca sexta and their possible roles in the expression regulation of immunity-related genes

Keywords: آلک; Posttranscriptional regulation; Illumina sequencing; Lepidoptera; Insect immunity; Target site prediction; Alk; anaplastic lymphoma kinase; AMP; antimicrobial peptides; ANKRD54; ankyrin repeat domain 54; Aop; anterior open; aPKC; atypical protein kinase C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors

Keywords: آلک; AEG-1; astrocyte elevated gene-1; ALK; anaplastic lymphoma kinase; ATP; adenosine triphosphate; BARD1; BRCA1-associated protein 1; BIM; B-cell lymphoma 2 interacting mediator of cell death; BRAF; v-raf murine sarcoma viral oncogene homolog B1; BRCA1; brea

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

A novel ALK rearrangement in an inflammatory myofibroblastic tumor in a neonate

Keywords: آلک; ALK; inflammatory myofibroblastic tumor; prenatal diagnosis; EXIT procedure; neonate;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Anaplastic lymphoma kinase-positive large B-cell lymphoma: a case report with particular immunophenotypic features

Keywords: آلک; Anaplastic lymphoma kinase-positive large B-cell lymphoma; ALK; Clathrin; Immunophenotype; Plasma cell differentiation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Adequacy of CT-guided biopsies with histomolecular subtyping of pulmonary adenocarcinomas: Influence of ATS/ERS/IASLC guidelines

Keywords: آلک; TTNB; Trans-Thoracic Needle core Biopsy; ALK; Anaplastic Lymphoma Kinase; FISH; Fluorescent In Situ Hybridization; CISH; Chromogenic In Situ Hybridization; EGFR; Epidermal Growth Factor Receptor; TKI; Tyrosine Kinase Inhibitor; FNA; Fine Needle Aspiration

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Mutual interaction of kisspeptin, estrogen and bone morphogenetic protein-4 activity in GnRH regulation by GT1-7 cells

Keywords: آلک; ActRІІ; activin type ІІ receptor; ALK; activin receptor-like kinase; ARC; arcuate nucleus; AVPV; anteroventral periventricular nucleus; BMP; bone morphogenetic protein; BMPRІІ; BMP type ІІ receptor; ER; estrogen receptor; ERK; extracellular signal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Melatonin receptor activation suppresses adrenocorticotropin production via BMP-4 action by pituitary AtT20 cells

Keywords: آلک; ACTH; adrenocorticotropin; ActRІІ; activin type ІІ receptor; ALK; activin receptor-like kinase; BMP; bone morphogenetic protein; BMPRІІ; BMP type ІІ receptor; CRH; corticotropin-releasing hormone; ERK; extracellular signal-regulated kinase; JNK; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells

Keywords: آلک; TGFβ; transforming growth factor β; BMP; bone morphogenetic protein; BMPR2; BMP type II receptor; ACVR2; activin type II receptor; ECD; extracellular domain; AMHR2; anti-Müllerian hormone type II receptor; TGFBR2; TGFβ type II receptor; FSH; follicle-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Anaplastic large cell lymphoma, ALK-negative

Keywords: آلک; Anaplastic lymphoma; CD30; ALK; Peripheral T-cell lymphoma; Autologous transplant; Allogeneic transplant;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species

Keywords: آلک; ALK; activin-like kinase; α-SMA; α-smooth muscle actin; BMP; bone morphogenic protein; CDK; chronic kidney disease; CTGF; connective tissue growth factor; DAB; 3,3′-diaminobenzidine; DPI; diphenyleneiodonium chloride; ECM; extracellular matrix; EGF; e

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

ReviewRole for membrane remodeling in cell death: Implication for health and disease

Keywords: آلک; Aβ; amyloid-β-peptide; ALK; anaplastic lymphoma kinase; AMBRA; activating molecule in Beclin-1-regulated autophagy protein 1; ASM; acid sphingomyelinase; ATG; autophagy-related gene; B[a]P; benzo[a]pyrene; cav-1; caveolin-1; DCC; deleted in colorectal c

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه