Keywords: آلفا سینوئولین; Alpha-synuclein; Oligomerization; Dopamine; Copper; DOPAL; Parkinson disease;
مقالات ISI آلفا سینوئولین (ترجمه نشده)
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Keywords: آلفا سینوئولین; Parkinson; Alpha-synuclein; Aggregation; Isoforms;
Keywords: آلفا سینوئولین; Alpha-synuclein; Multiple system atrophy; Synucleinopathies; Disease-modifying; Therapeutic strategies;
Keywords: آلفا سینوئولین; Alzheimer's disease; Psychosis; Tau; Dementia with Lewy bodies; Alpha-synuclein; Neurofibrillary tangles;
Keywords: آلفا سینوئولین; PD; Parkinson's disease; ASYN; alpha-synuclein; CT cybrids; (control cybrids); sPD cybrids; (sporadic Parkinson's disease cybrids); mtDNA; mitochondrial DNA; MPP+; 1-methyl-4-phenylpyridinium; NAP; Mitochondria dynamics; Microtubule network;
Keywords: آلفا سینوئولین; Alpha-synuclein; Autotoxicity; Catecholamine; DOPAL; Parkinson diseaseALDH, aldehyde dehydrogenase; AR, aldehyde reductase; BRA, baroreflex area; CSF, cerebrospinal fluid; DA, dopamine; DHPG, 3,4-dihydroxyphenylglycol; DOPAC, 3,4-dihydroxyphenylacetic aci
Keywords: آلفا سینوئولین; MSA; multiple system atrophy; MSA-P; parkinsonian variant of MSA; MSA-C; cerebellar variant of MSA; α-Syn; alpha-synuclein; SND; striatonigral degeneration; OPCA; olivopontocerebellar atrophy; GCI; (oligodendro-)glial cytoplasmic inclusions; UMSARS; unif
Keywords: آلفا سینوئولین; Alpha-synuclein; Lipid droplets; Peroxisome; Parkinson's disease;
Keywords: آلفا سینوئولین; Parkinson's disease; Autonomic nervous system; Alpha-synuclein; Heart;
Keywords: آلفا سینوئولین; Parkinson's disease; Glucocerebrosidase; Autophagy; Mitochondria; Oxidative stress; Free radicals; Alpha-synuclein; Membrane potential; Neurodegeneration; Gaucher disease;
Keywords: آلفا سینوئولین; Parkinson's disease; Alpha-synuclein; Cyclin-dependent kinase 5; Phosphorylation; p35; Calpain;
Keywords: آلفا سینوئولین; Alpha-synuclein; Cerebrospinal fluid; Dementia with Lewy bodies; Biomarker; Dementia;
Keywords: آلفا سینوئولین; Alpha-synuclein; Oxidative stress; Calcium; Parkinson's disease;
Keywords: آلفا سینوئولین; Silica nanoparticles; Parkinson diseases; Alpha-synuclein; Ubiquitin-proteasome system; Autophagy
Modulating α-synuclein fibril formation using DNA tetrahedron nanostructures
Keywords: آلفا سینوئولین; Alpha-synuclein; DNA tetrahedron; Amyloid; Parkinson's disease;
The different faces of the p. A53T alpha-synuclein mutation: A screening of Greek patients with parkinsonism and/or dementia
Keywords: آلفا سینوئولین; A53T; Parkinsonism; Dementia; Parkinson's disease; Frontotemporal dementia; Greek cohort; Alpha-synuclein;
The cortical excitability profile of patients with the G209A SNCA mutation versus patients with sporadic Parkinson's disease: A transcranial magnetic stimulation study
Keywords: آلفا سینوئولین; Alpha-synuclein; MEP I/O curves; Parkinson's disease; Silent period; Transcranial magnetic stimulation;
The interaction between calcineurin and α-synuclein is regulated by calcium and calmodulin
Keywords: آلفا سینوئولین; Alpha-synuclein; Calcineurin; Microscale thermophoresis; GST pull-down assays; Co-immunoprecipitation; Thapsigargin;
Les synucléinopathies sont-elles des maladies à prions ?
Keywords: آلفا سینوئولین; Synucléinopathies; Prion; Alpha-synucléine; Synucleinopathies; Prion; Alpha-synuclein;
Present and future of disease-modifying therapies in multiple system atrophy
Keywords: آلفا سینوئولین; Treatment; Disease modifying therapies; Clinical trials; Alpha-Synuclein;
Degradation of alpha-synuclein by dendritic cell factor 1 delays neurodegeneration and extends lifespan in Drosophila
Keywords: آلفا سینوئولین; Parkinson's disease; DCF1; Alpha-synuclein; Aging; Neurodegeneration;
Exacerbation of sensorimotor dysfunction in mice deficient in Atp13a2 and overexpressing human wildtype alpha-synuclein
Keywords: آلفا سینوئولین; ATP13A2; Alpha-synuclein; Mice; Sensorimotor; Phenotype;
Drp-1 dependent mitochondrial fragmentation and protective autophagy in dopaminergic SH-SY5Y cells overexpressing alpha-synuclein
Keywords: آلفا سینوئولین; alpha-synuclein; Parkinson's Disease; mitochondria; mitochondrial dynamics; autophagy; mitophagy;
Regional expression of genes mediating trans-synaptic alpha-synuclein transfer predicts regional atrophy in Parkinson disease
Keywords: آلفا سینوئولین; Parkinson disease; LAG3; Alpha-synuclein; Trans-synaptic spread; Atrophy; Genetic analysis;
Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance
Keywords: آلفا سینوئولین; AD; Alzheimer's disease; AFM; atomic force microscopy; APP; amyloid precursor protein; Aβ; amyloid-β peptide; DHA; dihydro ascorbic acid; EPR; electron paramagnetic resonance; FAD; familial Alzheimer's disease; hAβ, hIAPP; human peptides; IAPP; isl
The PMR1 pump in alpha-synuclein toxicity and neurodegeneration
Keywords: آلفا سینوئولین; AAV; adeno-associated virus; CEDE; calcium-evoked dendritic exocytosis; ER; endoplasmic reticulum; MSA; multiple system atrophy; PMCA; plasma membrane Ca2+ ATPase; SERCA; sarco/ER Ca2+-transport ATPase; SNARE; SNAP receptor; Alpha-synuclein; ATPase; Caeno
Alpha-synuclein aggregates in the parotid gland of idiopathic REM sleep behavior disorder
Keywords: آلفا سینوئولین; REM sleep behavior disorder; Alpha-synuclein; Parotid gland;
Astroglial and microglial contributions to iron metabolism disturbance in Parkinson's disease
Keywords: آلفا سینوئولین; Astroglia; Microglia; Iron; Alpha-synuclein; Parkinson's disease;
MicroRNA-7 facilitates the degradation of alpha-synuclein and its aggregates by promoting autophagy
Keywords: آلفا سینوئولین; α-Syn; alpha-Synuclein; bFGF; basic fibroblast growth factor; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; miR-7; microRNA-7; miR-SC; scrambled microRNA control; MPTP; 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine; PD; Park
Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study
Keywords: آلفا سینوئولین; PD; Parkinson's disease; DAT; dopamine transporter; PARS; Parkinson's Associated Risk Syndrome; AD; Alzheimer's disease; α-syn; alpha-synuclein; CSF; cerebrospinal fluid; UPSIT; University of Pennsylvania Smell Identification Test; [123]β-CIT; [123I]-fl
α-Synuclein Oligomers Induce a Unique Toxic Tau Strain
Keywords: آلفا سینوئولین; Alpha-synuclein; Oligomeric complexes; Seeding; Strain; Tau oligomers; Toxicity;
Correlations between CSF proteins and spontaneous neuronal activity in Parkinson's disease
Keywords: آلفا سینوئولین; BJLO; Benton Judgment of Line Orientation; fALFF; fractional amplitude of low-frequency fluctuation; HVLT-R; Hopkins Verbal Learning Test-Revised; HVLT-R_Dis_Rec; Hopkins Verbal Learning Test-Revised recognition discrimination index; LNS; Letter Number Se
Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death
Keywords: آلفا سینوئولین; Neurodegeneration; Synucleinopathies; Alpha-Synuclein; PKR; EIF2AK2; Phosphorylation; Cytotoxicity;
Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease
Keywords: آلفا سینوئولین; α-Syn; alpha-Synuclein; h-α-Syn; transgenic human alpha-Synuclein; D1 receptor; dopamine receptor type 1; D2 receptor; dopamine receptor type 2; DA; dopamine; DAT; dopamine transporter; VMAT2; vesicular monoamine transporter 2; DOPAC; 3,4-dihydroxypheny
C-terminal truncation exacerbates the aggregation and cytotoxicity of α-Synuclein: A vicious cycle in Parkinson's disease
Keywords: آلفا سینوئولین; α-Syn; alpha-synuclein; α-Syn FL; full-length alpha-synuclein; α-Syn121; C-terminal truncated alpha-synuclein 1-121; C19; C-terminal 19-residues peptide of alpha-synuclein; CD; circular dichroism; DLB; dementia with Lewy bodies; DLS; dynamic light scat
The lysosomal enzyme alpha-Galactosidase A is deficient in Parkinson's disease brain in association with the pathologic accumulation of alpha-synuclein
Keywords: آلفا سینوئولین; 4-MUG; 4-methylumbelliferone α-d-galactopyranoside; GalNAc; N-acetyl-d-galactosamine; α-Gal A; alpha-Galactosidase A; α-syn; alpha-synuclein; ALP; autophagy-lysosome pathway; Cat B; cathepsin B; Cat D; cathepsin D; Gb3; globotriaosylceramide; lyso-Gb3;
Epothilone D inhibits microglia-mediated spread of alpha-synuclein aggregates
Keywords: آلفا سینوئولین; α-syn; α-Synuclein; EpoD; Epothilone D; MSA; Multiple System Atrophy; PD; Parkinson's Disease; CNS; Central nervous system; DLB; Dementia with Lewy Bodies; LB; Lewy Bodies; GCI; Glial Cytoplasmic Inclusion; PMA; Phorbol-12-Myristate-13-Acetate; HAPI; Hi
Osmotic stress induced toxicity exacerbates Parkinson's associated effects via dysregulation of autophagy in transgenic C. elegans model
Keywords: آلفا سینوئولین; PD; Parkinson's disease; α-synuclein; alpha-synuclein; C.elegans; Caenorhabditis elegans; ROS; reactive oxygen species; NGM; nutrient growth medium; H2-DCF-DA; 2, 7-dichlorodihydrofluorescein-diacetate; SP; spermidine; WT; wortmannin; HN; high osmotic; L
Mitochondrial ROS-mediated post-transcriptional regulation of α-synuclein through miR-7 and miR-153
Keywords: آلفا سینوئولین; α-SYN; alpha-synuclein; ROS; reactive oxygen species; 3â²-UTR; 3â²-untranslated region; DAT; dopamine transporter; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; α-synuclein; microRNA; 3â²-UTR; Mitochondria; Pa
Research articleBiochemical analysis of α-synuclein extracted from control and Parkinson's disease colonic biopsies
Keywords: آلفا سینوئولین; Alpha-synuclein; Phosphorylation; Western blot; Two-dimensional immunoblot; Gastrointestinal biopsy; Enteric nervous system;
Homozygous alpha-synuclein p.A53V in familial Parkinson's disease
Keywords: آلفا سینوئولین; Genetics; SNCA; Alpha-synuclein; Missense mutation; Parkinson's disease;
Research articleAn extract of the marine alga Alaria esculenta modulates α-synuclein folding and amyloid formation
Keywords: آلفا سینوئولین; Parkinson's disease; Alpha-synuclein; Amyloid; Protein misfolding; Brown seaweed; Alaria esculenta;
Impairment in the mesohippocampal dopamine circuit following exposure to the brominated flame retardant, HBCDD
Keywords: آلفا سینوئولین; Asyn; alpha-synuclein; BFR; brominated flame retardants; COMT; catechol-O-methyltransferase; DAB; 3,3â²-diaminobenzidine; DAT; dopamine transporter; HBCDD; hexabromocyclododecane; MAO-B; monoamine oxidase-B; NET; norepinephrine transporter; PBDE; polybro
Phycocyanin protects against Alpha-Synuclein toxicity in yeast
Keywords: آلفا سینوئولین; Phycocyanin; Alpha-synuclein; Proteostasis; Oxidative stress; Parkinson's disease;
Research reportRole of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation
Keywords: آلفا سینوئولین; Alpha-synuclein; Pesticides; Metals; Protein aggregation; Traumatic brain injury; Oxidative stress; Parkinson disease; Neurodegenerative disease;
Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice
Keywords: آلفا سینوئولین; GFAP; mGluR1; Alpha-synuclein; Permeability transition; Heterozygote; Mitochondria;
Ferroptosis and cell death mechanisms in Parkinson's disease
Keywords: آلفا سینوئولین; Alpha-synuclein; Cell death; Ferroptosis; Parkinson's disease; 6-OHDA; 6-hydroxydopamine; ACSL4; acyl-CoA synthetase long-chain family member 4; AIF; apoptosis-inducing factor; APP; amyloid precursor protein; αsyn; alpha-synuclein; CSF; cerebrospinal flu
Frontotemporal dementia as the presenting phenotype of p.A53T mutation carriers in the alpha-synuclein gene
Keywords: آلفا سینوئولین; Parkinson's disease; Alpha-synuclein; Frontotemporal dementia; Dysexecutive syndrome; Tau protein;
Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors
Keywords: آلفا سینوئولین; aSyn; Alpha-synuclein; PD; Parkinson's disease; PLCβ1; phospholipase Cβ1; PI(4,5)P2; phosphoinositide-4,5-bisphosphate; Gq-PCRs; Gq protein-coupled receptors; IP3; inositol-1,4,5-trisphosphate; DAG; diacylglycerol; PKC; protein kinase C; MAPKs; mitogen-
Treadmill exercise alleviates motor deficits and improves mitochondrial import machinery in an MPTP-induced mouse model of Parkinson's disease
Keywords: آلفا سینوئولین; Parkinson's disease; Alpha-synuclein; Mitochondrial dysfunction; Treadmill exercise; Mitochondrial import machinery;