دانلود مقالات ISI درباره بیماری آلزایمر + ترجمه فارسی

Autophagy, its mechanisms and regulation: Implications in neurodegenerative diseases

Keywords: بیماری آلزایمر; Ageing; Parkinson's disease; Alzheimer's disease; Huntington's disease; Amyotrophic lateral sclerosis;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

GuidelinesEvidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; ARAT; action research arm test; BDI; Beck Depression Inventory; BI; Barthel Index; DC; direct current; DLPFC; dorsolateral prefrontal cortex; EEG; electroencephalography; ERP; event-related potentials; FMA; Fugl-Meyer assessment

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Chitosan nanofilm and electrospun nanofiber for quick drug release in the treatment of Alzheimer's disease: In vitro and in vivo evaluation

Keywords: بیماری آلزایمر; Oral disintegrating film; Chitosan nanofiber; Chitosan nanoparticle; Alzheimer's disease; In vivo bioavailability;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties

Keywords: بیماری آلزایمر; Alzheimer's disease; Homoisoflavonoid; Mannich base derivatives; Acetylcholinesterase inhibitors; Monoamine oxidase B inhibitors; Multifunctional properties;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Vascular protective effects of KLF2 on Aβ-induced toxicity: Implications for Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Amyloid beta; Kruppel like factor 2; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Lipidomics in translational research and the clinical significance of lipid-based biomarkers

Keywords: بیماری آلزایمر; 5-HETE; 5-hydroxyicosatetraenoic acid; 12-HETE; 12-hydroxyicosatetraenoic acid; 15-HETE; 15-hydroxyicosatetraenoic acid; aa; diacyl; ae; acyl-alkyl; ACs; acylcarnitines; ACOG; The American College of Obstetricians and Gynecologists; AD; Alzheimer's dise

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Sparse shared structure based multi-task learning for MRI based cognitive performance prediction of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Multi-task learning; Proximal gradient; Regression; Biomarker discovery;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, biochemical evaluation, and molecular modeling studies of aryl and arylalkyl di-n-butyl phosphates, effective butyrylcholinesterase inhibitors

Keywords: بیماری آلزایمر; Cholinesterase; Alzheimer's disease; Organophosphates; Enzyme inhibition; Computational docking;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Late-Onset Alzheimer's Disease Polygenic Risk Profile Score Predicts Hippocampal Function

Keywords: بیماری آلزایمر; Alzheimer's disease; Episodic memory; Genetics; Hippocampal function; Neuroimaging genetics; Polygenic risk profile score; RPS;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Conformal invariants for multiply connected surfaces: Application to landmark curve-based brain morphometry analysis

Keywords: بیماری آلزایمر; Conformal invariant; Teichmüller shape space; Brain landmark curves; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents

Keywords: بیماری آلزایمر; Multitarget-directed ligands; Butyrylcholinesterase inhibitors; MAO-B inhibitors; Alzheimer's disease; Aβ; amyloid β; ACh; acetylcholine; mAChE; murine acetylcholinesterase; AD; Alzheimer's disease; BBB; blood-brain barrier; hBChE; human butyrylchol

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2017 سفارش ترجمه

Disordered APP metabolism and neurovasculature in trauma and aging: Combined risks for chronic neurodegenerative disorders

Keywords: بیماری آلزایمر; Aging; Alzheimer's disease; Amyloid-beta; Brain trauma; Neurodegeneration; Neurovascular unit;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

DNA damage in the oligodendrocyte lineage and its role in brain aging

Keywords: بیماری آلزایمر; Oligodendrocyte; DNA damage; Alzheimer's disease; Progeriod syndromes; White matter; Aging brain;

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; Aβ; amyloid-β peptide; FTDP-17; frontotemporal dementia and Parkinsonism linked to chromosome 17; GVD; granulovacuolar degeneration; mTOR; mammalian target of rapamycin; NFTs; neurofibrillary tangles; p70S6K; S6 kinases; PI3K;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

Protection against RAGE-mediated neuronal cell death by sRAGE-secreting human mesenchymal stem cells in 5xFAD transgenic mouse model

Keywords: بیماری آلزایمر; Alzheimer's disease; Soluble RAGE; Human UC-MSCs; Neuronal cell death; RAGE pathway; 5xFAD;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

Targeted delivery of rosmarinic acid across the blood-brain barrier for neuronal rescue using polyacrylamide-chitosan-poly(lactide-co-glycolide) nanoparticles with surface cross-reacting material 197 and apolipoprotein E

Keywords: بیماری آلزایمر; Alzheimer's disease; Neuron; Amyloid-β; SK-N-MC cell; RWA264.7 cell; Pharmacotherapy; Nanocarrier;

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; AGC; protein kinase A/protein kinase G/protein kinase C; Akt; protein kinase B; ATG13; autophagy-related gene 13; Aβ; amyloid-beta; BDNF; brain-derived neurotrophic factor; CaMKII; Ca2+/calmodulin-dependent kinase II; cAMP; cyc

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

VEGF mimic peptides: Potential applications in central nervous system therapeutics

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; ALS; Amyotrophic lateral sclerosis; AMD; age-related macular degeneration; ARE; adenine/uridine rich elements; BBB; blood brain barrier; CNS; central nervous system; CSF; cerebrospinal fluid; ECS; electroconvulsive shock; HA; hy

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

HIV/neuroAIDS biomarkers

Keywords: بیماری آلزایمر; Aβ42-β; amyloid of 42 kiloDaltons; AD; Alzheimer's disease; APP; amyloid precursor protein; ALS; amyotrophic lateral sclerosis; BOLD; blood oxygen level-dependent contrast imaging; cART; combination anti-retroviral therapy; CBF; cerebral blood flow; C

دانلود رایگان متن کامل مقاله ISI 66 صفحه سال انتشار : 2017 سفارش ترجمه

The translocator protein (18 kDa) and its role in neuropsychiatric disorders

Keywords: بیماری آلزایمر; 3α-HSD; 3α-hydroxysteroid dehydrogenase; 3β-HSD; 3β-hydroxysteroid dehydrogenase/Δ5−Δ4; AIF; apoptosis inducing factor; AD; Alzheimer's disease; ANT; adenine nucleotide translocator; AP-1; activator protein 1; APAF-1; apoptotic peptidase activat

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2017 سفارش ترجمه

The double faced role of copper in Aβ homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration

Keywords: بیماری آلزایمر; Copper; Metal ions; Alzheimer's disease; Neurodegenerative diseases; Insulin-degrading enzyme (IDE); Proteasome; Ubiquitin; Autophagy; Proteostasis; Metallostasis; Ubiquitin proteasome system (UPS); Aging; 4-Hydroxy-2-nonenal (HNE); 4-Hydroxy-2-hexanal

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2017 سفارش ترجمه

Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer's disease

Keywords: بیماری آلزایمر; Aβ; amyloid β; AD; Alzheimer's disease; AFT complexes; APP/AICD-FE65-TIP60 complexes; AICD; APP intracellular domain; APLP1,2; amyloid precursor like protein 1,2; APP; amyloid precursor protein; ChIP; chromatin immuneprecipitation; CTF; C-terminal fra

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2017 سفارش ترجمه

Alzheimer's disease: How metal ions define β-amyloid function

Keywords: بیماری آلزایمر; Aβ1−40; β-Amyloid, 40-residue isoform; Aβ1−42; β-Amyloid, 42-residue isoform; Aβ1−42/Aβ1−40; Ratio between levels of Aβ1−42 and Aβ1−40; ADAM; A Disintegrin And Metalloprotease, zinc peptidases, some being α-secretases; AICD; APP intra

دانلود رایگان متن کامل مقاله ISI 112 صفحه سال انتشار : 2017 سفارش ترجمه

Convenient synthesis of (+)-cis-4-(N-adamantyl-N-methylamino)-2,3-methano-2-phenylbutan-1-ol as a candidate of anti-Alzheimer's medicine via catalytic enantioselective Simmons-Smith reaction using l-phenylalanine-derived disulfonamide

Keywords: بیماری آلزایمر; Alzheimer's disease; Sigma receptor agonist; Regioselective acetylation; Simmons-Smith reaction; Amidation;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperThe GBA, DYRK1A and MS4A6A polymorphisms influence the age at onset of Chinese Parkinson patients

Keywords: بیماری آلزایمر; Parkinson's disease; Alzheimer's disease; Age at onset;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of amyloid fibril formation and cytotoxicity by caffeic acid-conjugated amyloid-β C-terminal peptides

Keywords: بیماری آلزایمر; Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; DCFH-DA; 2′,7′-dichlorodihydrofluorescein diacetate; DHCA; dihydrocaffeic acid; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; Gly; glycine; HBTU; O

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Genetic analysis of TREM2 variants in Chinese Han patients with sporadic Parkinson's disease

Keywords: بیماری آلزایمر; PD; Parkinson's disease; AD; Alzheimer's disease; TREM2; the triggering receptor expressed on myeloid cells 2 gene; VPS35; the vacuolar protein sorting 35 gene; EIF4G1; the eukaryotic translation initiation factor 4-gamma 1 gene; S100B; the S100 calci

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Novel presenilin 1 mutation (Ile408Thr) in an Italian family with late-onset Alzheimer's disease

Keywords: بیماری آلزایمر; DNA; Alzheimer's disease; PSEN1; PSEN2; APP;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

The association between CYP46A1 rs4900442 polymorphism and the risk of Alzheimer's disease: A meta-analysis

Keywords: بیماری آلزایمر; Alzheimer's disease; rs4900442; CYP46A1; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Expression of Alzheimer's disease risk genes in ischemic brain degeneration

Keywords: بیماری آلزایمر; Alzheimer's disease; Brain ischemia; β-secretase; Presenilin 1 and 2; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Association study of the BIN1 and IL-6 genes on Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Case-control study; −174 G/C IL-6; Brazilian population;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of curcumin derivatives as tau and amyloid β dual aggregation inhibitors

Keywords: بیماری آلزایمر; Alzheimer's disease; Tau; Amyloid β; Aggregation inhibitor; Curcumin;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Research articleAssociation of DYRK1A polymorphisms with sporadic Parkinson's disease in Chinese Han population

Keywords: بیماری آلزایمر; PD; Parkinson's disease; Dyrk1A; dual-specificity tyrosine phosphorylation-regulated kinase 1A; SNPs; single nucleotide polymorphism; DA; dopamine; LBs; Lewy bodies; AD; Alzheimer's disease; HC; health control; NMS; none motor syndrome; UPDRS III; Uni

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Association of tripartite motif family-like 2 (TRIML2) polymorphisms with late-onset Alzheimer's disease risk in a Korean population

Keywords: بیماری آلزایمر; Alzheimer's disease; Tripartite motif family-like 2 (TRIML2) gene; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

The TOMM40 gene rs2075650 polymorphism contributes to Alzheimer's disease in Caucasian, and Asian populations

Keywords: بیماری آلزایمر; Genome-wide association studies; Alzheimer's disease; TOMM40 gene rs2075650 polymorphism; Asian; Caucasian;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Early alterations in blood and brain RANTES and MCP-1 expression and the effect of exercise frequency in the 3xTg-AD mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Exercise; Chemokines; Biomarkers;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; Aβ; amyloid β; APP; amyloid precursor protein; Bdnf; brain-derived neurotrophic factor; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; PBS; phosphate-buffered saline; Sirt1; Sirtuin 1; Amyloid β; Pin1; Sirtuin 1; Brain-deri

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

A sandwich immunoassay for detection of Aβ1-42 based on quantum dots

Keywords: بیماری آلزایمر; Sandwich immunoassay; Alzheimer's disease; Quantum dots; Amyloid-beta peptide; Magnetic beads;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

S-allyl-l-cysteine and isoliquiritigenin improve mitochondrial function in cellular models of oxidative and nitrosative stress

Keywords: بیماری آلزایمر; Mitochondrial dysfunction; Oxidative stress; Nrf2; Alzheimer's disease; Aging;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Imatinib methanesulfonate reduces hyperphosphorylation of tau following repeated peripheral exposure to lipopolysaccharide

Keywords: بیماری آلزایمر; AD; Alzheimer's Disease; APP; Amyloid Precursor Protein; Aβ; amyloid-beta; DU; Densitometry Units; GSK3α; glycogen synthase kinase 3α; HSP70; heat shock protein 70; IM; imatinib methanesulfonate; NFTs; neurofibrillary tangles; ptau; hyperphosphorylat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibiting receptor for advanced glycation end product (AGE) and oxidative stress involved in the protective effect mediated by glucagon-like peptide-1 receptor on AGE induced neuronal apoptosis

Keywords: بیماری آلزایمر; Glucagon-like peptide-1 receptor; Receptor for advanced glycation end products; Oxidative stress; Diabetes; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; BBB; blood brain barrier; Aβ; Amyloid beta; LRP1; low-density lipoprotein related protein 1; LXR; liver X receptor; GFAP; glial fibrillary acidic protein; Iba1; ionized calcium-binding adapter molecule 1; GW3965; Alzheimer's

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Research articleCerebral dopamine neurotrophic factor alleviates Aβ25-35-induced endoplasmic reticulum stress and early synaptotoxicity in rat hippocampal cells

Keywords: بیماری آلزایمر; CDNF; Amyloid-beta; Synapse; ER stress; Hippocampus; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Antibody modified-silver nanoparticles for colorimetric immuno sensing of Aβ(1-40/1-42) based on the interaction between β-amyloid and Cu2+

Keywords: بیماری آلزایمر; Alzheimer's disease; Silver nanoparticles; Colorimetric immunosensor; Aβ(1-40/1-42); Antibody; Cu2+;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportβ-amyloid increases neurocan expression through regulating Sox9 in astrocytes: A potential relationship between Sox9 and chondroitin sulfate proteoglycans in Alzheimer's disease

Keywords: بیماری آلزایمر; Sox9; Chondroitin sulfate proteoglycans; Neurocan; β-amyloid; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperProtective effects of a Chotosan Fraction and its active components on β-amyloid-induced neurotoxicity

Keywords: بیماری آلزایمر; CTS; chotosan; CTS-E; chotosan ethyl acetate fraction; AD; Alzheimer's disease; Aβ; β-amyloid; QTOFMS; quadrupole time-of-flight mass spectrometry; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; ThT; thioflavon T; ROS; reactive oxygen species; DAD; diode ar

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents

Keywords: بیماری آلزایمر; Berberine; Acetylcholinesterase; Antioxidants; Phenethylamines; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core

Keywords: بیماری آلزایمر; LXR; Structure-based drug design; Alzheimer's disease; Brain;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and evaluation of copper-64 labeled benzofuran derivatives targeting β-amyloid aggregates

Keywords: بیماری آلزایمر; β-Amyloid; Alzheimer's disease; PET; Imaging; Copper-64;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Polyphenols isolated from leaves of Vitis thunbergii var. taiwaniana regulate APP related pathway

Keywords: بیماری آلزایمر; Vitis thunbergii var. taiwaniana; Alzheimer's disease; Polyphenols; Aβ; APP related pathway;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه