دانلود مقالات ISI درباره بیماری آلزایمر + ترجمه فارسی

Sleep deprivation accelerates the progression of alzheimer's disease by influencing Aβ-related metabolism

Keywords: بیماری آلزایمر; Sleep; Sleep deprivation; Alzheimer's disease; β-amyloid peptide(Aβ);

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Spatio-temporal and kinematic gait analysis in patients with Frontotemporal dementia and Alzheimer's disease through 3D motion capture

Keywords: بیماری آلزایمر; Gait analysis; Kinematics; Frontotemporal dementia; Alzheimer's disease; Executive functions; Cognition;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular interaction studies of acetylcholinesterase with potential acetylcholinesterase inhibitors from the root of Rhodiola crenulata using molecular docking and isothermal titration calorimetry methods

Keywords: بیماری آلزایمر; Rhodiola crenulata; Alzheimer's disease; Acetylcholinesterase; Molecular docking; Isothermal titration calorimetry;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice

Keywords: بیماری آلزایمر; CHMs; Chinese herbal medicines; ATG; autophagy-related proteins; AD; Alzheimer's disease; PD; Parkinson's disease; AMPK; 5′ adenosine monophosphate-activated protein kinase; mTOR; mammalian target of rapamycin; HD; Huntington's disease; HH; hedera

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Self-reported traumatic brain injury and in vivo measure of AD-vulnerable cortical thickness and AD-related biomarkers in the ADNI cohort

Keywords: بیماری آلزایمر; Traumatic brain injury; Alzheimer's disease; Cortical thickness; CSF biomarkers; Beta-amyloid; Tau;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate

Keywords: بیماری آلزایمر; SVCT; sodium-dependent vitamin C transporter; APP; amyloid precursor protein; PSEN1; presenilin 1; ASC; ascorbate; ROS; reactive oxygen species; Aβ; amyloid beta peptide; TMRE; tetramethylrhodamine, ethyl ester; Alzheimer's disease; Mitochondria; Oxida

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Cognitive ability in Down syndrome and its relationship to urinary neopterin, a marker of activated cellular immunity

Keywords: بیماری آلزایمر; Down syndrome; Aging; Alzheimer's disease; Memory; Neopterin; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Meta-analyses of RELN variants in neuropsychiatric disorders

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; ADHD; attention deficit hyperactivity disorder; ASD; autistic spectrum disorder; BD; bipolar disorders; SZ; schizophrenia; SNPs; single nucleotide polymorphisms; RELN gene; Psychiatric disorders; Single nucleotide polymorphism;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Mitochondrial transcription factor A (TFAM) rs1937 and AP endonuclease 1 (APE1) rs1130409 alleles are associated with reduced cognitive performance

Keywords: بیماری آلزایمر; APE1; AP endonuclease 1; PolB; polymerase β; PolG; polymerase γ; BER; base excision repair; CSF; cerebral spinal fluid; MMSE; mini mental state examination; SNP; single nucleotide polymorphisms; TFAM; mitochondrial transcription factor A; AD; Alzheimerâ

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Platelets are responsible for the accumulation of β-amyloid in blood clots inside and around blood vessels in mouse brain after thrombosis

Keywords: بیماری آلزایمر; Aβ; amyloid beta; APP; amyloid precursor protein; BBB; blood-brain barrier; AD; Alzheimer's disease; Aβ-peptide; Alzheimer; Platelets; Thrombosis;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Increased Levels of the Bullous Pemphigoid BP180 Autoantibody Are Associated with More Severe Dementia in Alzheimer's Disease

Keywords: بیماری آلزایمر; Aβ1-42; beta-amyloid; AD; Alzheimer's disease; BP; bullous pemphigoid; CSF; cerebrospinal fluid; IF; immunofluorescence; MMSE; mini-mental state examination; NC16A; noncollagenous 16A; p-tau181; hyperphosphorylated tau;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Age-related alterations of neuronal excitability and voltage-dependent Ca2+ current in a spontaneous mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Neuronal excitability; Voltage-dependent Ca2+ current; Hippocampus;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Autophagy, mitophagy and apoptotic gene changes in the hippocampal CA1 area in a rat ischemic model of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Brain ischemia; Hippocampal CA1 area; Delayed neuronal death; Genes;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

TREM2, Microglia, and Neurodegenerative Diseases

Keywords: بیماری آلزایمر; TREM2; Alzheimer's disease; microglia; APOE; clusterin; APOJ; lipoproteins; neurodegenerative disease; Nasu-Hakola disease; PLOSL; frontotemporal dementia; multiple sclerosis;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNA-144 modulates oxidative stress tolerance in SH-SY5Y cells by regulating nuclear factor erythroid 2-related factor 2-glutathione axis

Keywords: بیماری آلزایمر; microRNA-144; Alzheimer's disease; Oxidative stress; Nuclear factor erythroid 2-related factor 2;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Methylation analysis of DNA repair genes in Alzheimer's disease

Keywords: بیماری آلزایمر; DNA methylation; Alzheimer's disease; Epigenetics; DNA repair; OGG1; PARP1 BRCA1; MGMT; MLH1; MRE11A;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Piracetam inhibits ethanol (EtOH)-induced memory deficit by mediating multiple pathways

Keywords: بیماری آلزایمر; ACSF; artificial cerebrospinal fluid; AD; Alzheimer's disease; AMPARs; α-amino-3-hy-droxy-5-methyl-4-isoxazolepropionic acid receptors; ethanol; EtOH; fEPSPs; field excitatory post-synaptic potentials; LTP; long-term potentiation; NAC; N-acetylcysteine

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewThoughts on interactions between PGRMC1 and diverse attested and potential hydrophobic ligands

Keywords: بیماری آلزایمر; ABCB10; ATP Binding Cassette Subfamily B Member 10; ACBD3; acyl-CoA binding domain-containing 3; AD; Alzheimer's disease; ANT2; ADP/ATP translocase 2; ATAD3; ATPase family AAA domain-containing protein 3A; CBS; cystathionine β-synthase; CK2; Casein kin

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Extraction and in vitro screening of potential acetylcholinesterase inhibitors from the leaves of Panax japonicus

Keywords: بیماری آلزایمر; Leaves of Panax japonicus; Alzheimer's disease; Acetylcholinesterase; Centrifugal partition chromatography;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Early identification of mild cognitive impairment using incomplete random forest-robust support vector machine and FDG-PET imaging

Keywords: بیماری آلزایمر; FDG-PET; Alzheimer's disease; Mild cognitive impairment; Robust optimization;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Loss of nitrergic and cholinergic neurons in the enteric nervous system of APP/PS1 transgenic mouse model

Keywords: بیماری آلزایمر; Alzheimer's disease; Enteric nervous system; Nitrergic neuron; Cholinergic neuron;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Ser422 phosphorylation blocks human Tau cleavage by caspase-3: Biochemical implications to Alzheimer's Disease

Keywords: بیماری آلزایمر; Aa; amino acid; ACN; acetonitrile; AUFS; absorbance units full scale; CHCA; 1-Cyano 4-Hydroxy Cinnamic Acid; Da; Dalton; DHB; 2,5-dihydroxy benzoic acid; DMF; N,N′-dimethyl formamide; EDT; ethane dithiol; h; human; HATU; 1-[Bis(dimethylamino)methylene]-

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Astrocyte elevated gene-1 (AEG-1) and the A(E)Ging HIV/AIDS-HAND

Keywords: بیماری آلزایمر; Astrocytes; Aging; HIV-associated neurocognitive disorders; Neuroinflammation; ER/Nucleolar/Oxidative stress; Excitotoxicity; Aβ; amyloid beta; AEG-1; astrocyte elevated gene-1; AD; Alzheimer's disease; AIDS; acquired immune deficiency syndrome; ARE; a

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Mitochondrial depletion in CD4+ and CD19+ peripheral lymphocytes in early stage Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Lymphocytes; Mitochondria; Mitochondrial depletion; mtDNA;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Putting attention in the spotlight: The influence of APOE genotype on visual search in mid adulthood

Keywords: بیماری آلزایمر; APOE; Cognitive aging; Alzheimer's disease; Attention; Visuospatial; Mid-adulthood;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of breviscapine on amyloid beta 1-42 induced Alzheimer's disease mice: A HPLC-QTOF-MS based plasma metabonomics study

Keywords: بیماری آلزایمر; Breviscapine; Alzheimer's disease; Mice; Amyloid beta 1-42; Metabonomics; HPLC-QTOF-MS;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Pyridoxine-resveratrol hybrids Mannich base derivatives as novel dual inhibitors of AChE and MAO-B with antioxidant and metal-chelating properties for the treatment of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Pyridoxine-Resveratrol hybrids; Mannich base derivatives; AChE inhibitors; MAO-B inhibitors; Antioxidant; Metal-chelating;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Risperidone ameliorated Aβ1-42-induced cognitive and hippocampal synaptic impairments in mice

Keywords: بیماری آلزایمر; Alzheimer's disease; Risperidone; Cognitive impairment; Aβ1-42;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

A protocol for quantitative analysis of murine and human amyloid-β1-40 and 1-42

Keywords: بیماری آلزایمر; Amyloid-beta; Aβ; ELISA; Alzheimer's disease; 5XFAD; Ts65Dn;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Altered cerebral insulin response in transgenic mice expressing the epsilon-4 allele of the human apolipoprotein E gene

Keywords: بیماری آلزایمر; APOE4; Alzheimer's disease; Insulin;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

CD36 Deficiency Suppresses Epileptic Seizures

Keywords: بیماری آلزایمر; AA; arachidonic acid; ACSF; artificial cerebral spinal fluid; AD; Alzheimer's disease; ANOVA; analysis of variance; APs; action potentials; Aβ; amyloid-β peptide; CD36; cluster of differentiation 36; CNS; central nervous system; HEPS; (4-(2-hydroxyeth

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Tongxinluo improves cognition by decreasing β-amyloid in spontaneous hypertensive rats

Keywords: بیماری آلزایمر; TXL; tongxinluo; AD; Alzheimer's disease; HTN; hypertension; SHRs; spontaneously hypertensive rats; WKY; (normotensive) Wistar Kyoto rats; RAGE; receptor for advanced glycation end products; Aβ; β-amyloid; APP; amyloid precursor protein; BBB; blood-br

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Sausage tree (Kigelia africana) flavonoid extract is neuroprotective in AlCl3-induced experimental Alzheimer's disease

Keywords: بیماری آلزایمر; Acetylcholinesterase; Butyrylcholinesterase; Alzheimer's disease; Kigelia africana; Flavonoid-rich fraction; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

A novel relational regularization feature selection method for joint regression and classification in AD diagnosis

Keywords: بیماری آلزایمر; Alzheimer's disease; Feature selection; Sparse coding; Manifold learning; MCI conversion;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Cognitive behavioral therapy (CBT) for preventing Alzheimer's disease

Keywords: بیماری آلزایمر; AD; alzheimer's disease; Ab; amyloid beta; B-NC; brain-nasal cavity; CBT-I; cognitive behavioral therapy for insomnia; FINGER; finnish geriatric intervention study to prevent cognitive impairment and disability; LOAD; late onset AD; MCI; mild cognitive

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, biological evaluation and docking studies of 2,3-dihydroquinazolin-4(1H)-one derivatives as inhibitors of cholinesterases

Keywords: بیماری آلزایمر; 2,3-Dihydroquinazolin-4(1H)-one; Dual inhibitors; Cholinesterases; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Thermosensitive in situ nanocomposite of rivastigmine hydrogen tartrate as an intranasal delivery system: Development, characterization, ex vivo permeation and cellular studies

Keywords: بیماری آلزایمر; Poly(lactic-co-glycolic acid); Rivastigmine; Nanoparticle; Hydrogel; Nasal; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Investigating the amyloid-beta enhancing effect of cGMP in neuro2a cells

Keywords: بیماری آلزایمر; Alzheimer's disease; Amyloid precursor protein; APP; Cyclic guanosine monophosphate; Vardenafil;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, docking study and neuroprotective effects of some novel pyrano[3,2-c]chromene derivatives bearing morpholine/phenylpiperazine moiety

Keywords: بیماری آلزایمر; Alzheimer's disease; Cholinesterase inhibition; Coumarins; Neuroprotection; β-Secretase inhibition;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6J mice. A potential model of sporadic Alzheimer's disease

Keywords: بیماری آلزایمر; Aβ; β-amyloid; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; ANS; autonomic nervous system; BACE1; beta-site APP-cleaving enzyme 1; BBB; brain blood barrier; CSF; cerebrospinal fluid; DIO; diet-induced obesity; HCD; high calorie diet; H

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; ADP; adenosine diphosphate; ANOVA; analysis of variance; ATP; adenosine triphosphate; Aβ; amyloid β; ETC; electron-transport chain; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; mtMP; mitochondrial membrane poten

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Puerarin suppression of Aβ1-42-induced primary cortical neuron death is largely dependent on ERβ

Keywords: بیماری آلزایمر; Puerarin; Estrogen receptor; Alzheimer's disease; Amyloid beta; Neuroprotection; Cortical neuron;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

The neuroprotective effects of Berberine against amyloid β-protein-induced apoptosis in primary cultured hippocampal neurons via mitochondria-related caspase pathway

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; Aβ; β-amyloid protein; DMEM; Dulbecco's modified eagle's medium; FBS; fetal bovine serum; PDL; poly-d-lysine; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliu-m bromide; DMSO; dimethyl sulfoxide; PVDF; Polyvinylide

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, physicochemical and biological studies of technetium-99m labeled tacrine derivative as a diagnostic tool for evaluation of cholinesterase level

Keywords: بیماری آلزایمر; Tac; tacrine (1,2,3,4-tetrahydroacridin-9-amine); AD; Alzheimer's disease; AChE; acetylcholinesterase; CNS; central nervous system; IC50; half maximal inhibitory concentration; BM; biologically active molecule; BFCA; Bifunctional Coupling Agent; NS3; tr

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Exploring putative inhibitors of Death Associated Protein Kinase 1 (DAPK1) via targeting Gly-Glu-Leu (GEL) and Pro-Glu-Asn (PEN) substrate recognition motifs

Keywords: بیماری آلزایمر; DAPK1; Death Associated Protein Kinase 1; NMDARs; N-methyl-D-aspartate receptors; NMDAR2A or NR2A; N-methyl-D-aspartate receptor subtype 2A; NMDAR2B or NR2B; N-methyl-D-aspartate receptor subtype 2B; NSC; neuronal survival-signaling complex; NDC; neuronal

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

miR-124 downregulates BACE 1 and alters autophagy in APP/PS1 transgenic mice

Keywords: بیماری آلزایمر; BACE1; beta-site APP-cleaving enzyme 1; miRNAs; microRNAs; miR-124; microRNA-124; Aβ; amyloid-beta; AD; Alzheimer's disease; APP; amyloid precursor protein; DG; dentate gyrus; MTIs; miRNA-target interactions; LC3II; Light Chain 3 II; PVDF; Polyvinylidene

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological evaluation of 4′-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Chalcone carbamate derivatives; Multifunctional agents; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Monoamine oxidase B inhibitors;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Protective effects of kinetin against aluminum chloride and D-galactose induced cognitive impairment and oxidative damage in mouse

Keywords: بیماری آلزایمر; Aβ1-42; beta-amyloid protein 1-42; ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AGEs; advanced glycation end products; AlCl3; aluminum trichloride; APP; β-amyloid precursor protein; CAT; catalase; d-gal; d-galactose; 8-is

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Netrin-1 improves the amyloid-β-mediated suppression of memory and synaptic plasticity

Keywords: بیماری آلزایمر; Beta amyloid; Netrin-1; Long-term potentiation; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of mutation on Aβ1-42-Heme complex in aggregation mechanism: Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Molecular dynamic simulation; Heme; Aβpeptides; His13Gly mutation;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه