Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AN; adult neurogenesis; AHR; aryl hydrocarbon receptor; APC; adenomatous polyposis coli; ARE; antioxidant responsive element; Axin; tumor suppressors Axin; aNSCs; adult neural stem cells; BMSCs; bone marrow-derived mesenchymal stem cells; BMPs; bone morph
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Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AD; Alzheimer's disease; PPs; polyphenols; EGCG; epigallocatechin gallate; NFTs; neurofibrillary tangles; ACh; acetylcholine; Aβ; amyloid-beta; APP; amyloid precursor protein; PS-1; presenilin-1; PS-2; presenilin-2; AChE; acetylcholine esterase; Cdk5;
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Sciatic nerve crush; Curcumin; Oxidative stress; Myelin; ARE; Antioxidant responsive element; APL; Area per lipid; BW; Beam walking; CMAP; Compound muscle action potential; GST-P; Glutathione S-transferase P; HES; Haematoxylin-eosin-safran; HO-1; Heme-oxy
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Strawberry; LPS; Human Dermal Fibroblast; Inflammation; Oxidative stress; Antioxidant response; Prevention; 2-DG; 2-deoxyglucose; 2,4 DNP; 2,4-Dinitrophenol; ABB; annexin binding buffer; ABTS; 2,20-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) diammo
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; PD; Parkinson's disease; AD; Alzheimer's disease; EGCG; (â)-Epigallocatechin-3-gallate; NRF2; NF-E2-related factor 2; ROS; reactive oxygen species; H2O2; hydrogen peroxide; ER; endoplasmic reticulum; GPX; glutathione-peroxidase; NOX; NADPH oxidases (NOX
Comparison of chemical structures and cytoprotection abilities between direct and indirect antioxidants
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AAPH; 2,2â²-azobis (2-amidinopropane) dihydrochloride; ARE; antioxidant responsive element; CAT; catalase; DHMBA; 3,5-dihydroxy-4-methoxybenzyl alcohol; DPPH; 2,2-diphenyl-1-picryl-hydrazyl; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phosphate dehy
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; 2,4-D; dichlorophenoxyacetic acid; [35S]TBPS; [35S]tertiary-butylbicyclophosphorothionate; 3-NP; 3-nitropropionic acid; 4CL; 4-coumarate: CoA ligase; 4-O-MH; 4-O-methylhonokiol; 6-OHDA; 6-hydroxydopamine; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; AChE; acetylc
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; OS; oxidative stress; ROS; reactive oxygen species; CNS; central nervous system; PD; Parkinson's disease; AD; Alzheimer's disease; GSH; reduced glutathione; GST; glutathione transferase; GSSG; glutathione disulfide; SN; substantia nigra; BSO; L-buthionine
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AD; Alzheimer׳s disease; APP/PS1; amyloid precursor protein/presenilin 1; ARE; antioxidant responsive element; CAT; activity of catalase; CBP; cAMP-responsive element binding protein (CREB)-binding protein; DTNB; dithionitrobenzoic acid; ECL; electrochem
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; APP; amyloid precursor protein; ARE; antioxidant responsive element; BSO; buthionine sulfoximine; DMT1; divalent metal ion transporter; Ft-H; ferritin-H; FAC; ferric ammonium citrate; Fpn; ferroportin; GSH; glutathione; GFP; green fluorescent protein; IRE
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ARE; Antioxidant responsive element; Cul3; Cullin 3; DEVD; Asp-Glu-Val-Asp; DOX; Doxorubicin; GCLC; Catalytic subunit of glutamate-cysteine ligase; GCLM; Modified subunit of glutamate-cysteine ligase; GSTA4-4; Glutathione S-transferase alpha 4;
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AOPPs; advanced oxidation protein products; ARE; antioxidant responsive element; Dityr; dityrosine; ET-1; endothelin-1; H-E; hematoxylin and eosin; MDA; malondialdehyde; OPPs; oxidized protein products; Pox; protein oxidation; PC; protein carbonyl; ROS;
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; A-As; acute arsenic-exposed; ANOVA; analysis of variance; ARE; antioxidant responsive element; BHA; butylated hydroxyanisole; BSO; buthionine sulfoximine; C-As; chronic arsenic-exposed; DTNB; 5,5â²-dithiobis-(2-nitrobenzoic acid); ERK1/2; extracellular s
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AP-1; Activator protein-1; APE; Apurinic/apyrimidinic endonuclease; ARE; Antioxidant response element; ChIP; Chromatin immunoprecipitation; CRE; cAMP response element; CREB; CRE binding protein; Egr-1; Early growth response factor-1; EMSA; Electrophoretic
Bardoxolone methyl induces neuritogenesis in Neuro2a cells
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Akt; v-Akt Murine Thymoma Viral Oncogene; ARE; Antioxidant Responsive Element; BDNF; Brain Derived Neurotrophic Factor; CDDO; 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; CHOP; C/EBP homologous protein; DR5; Death Receptor 5; ERK; Extracellular signal Re
γ-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ALT; alanine aminotransferase; ARE; antioxidant responsive element; AST; aspartate transaminase; ATRA; all--retinoid acid; CCl4; carbon tetrachloride; DCFH-DA; 2â²,7â²-dichlorofluorescin diacetate; γ-man; γ-mangostin; GSH; glutathione; HO-1; heme oxyg
ETS-domain containing protein (Elk1) suppression protects cortical neurons against oxygen-glucose deprivation injury
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Elk1; ETS-domain containing protein; OGD; oxygen-glucose deprivation; Fra-1; Fos-related antigen 1; Nrf2; Nuclear factor erythroid 2-related factor; ARE; antioxidant responsive element; ROS; reactive oxygen species; SD; Sprague-Dawley; FBS; fetal bovine s
Ziziphus spina-christi fruit extract suppresses oxidative stress and p38 MAPK expression in ulcerative colitis in rats via induction of Nrf2 and HO-1 expression
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AcOH; acetic acid; ARE; antioxidant responsive element; Cas-3; caspase-3; CAT; catalase; CMIS; colonic mucosal injury score; COX; cyclooxygenase; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GRd; glutathione reductase; GPx; glutathione peroxidase; H&E
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ARE; antioxidant responsive element; ChIP; chromatin immunoprecipitation; EdU; 5-ethynyl-2â²-deoxyuridine; IMQ; imiquimod; K; keratin; pNrf2; phosphorylated Nrf2; siRNA; small interfering RNA; TNF-α; tumor necrosis factor-α;
Hydrogen sulfide-producing cystathionine γ-lyase is critical in the progression of kidney fibrosis
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; CSE; Cystathionine γ-lyase; H2S; Hydrogen sulfide; GSH; Glutathione; CKD; Chronic kidney disease; UUO; Unilateral ureteral obstruction; P5P; Pyridoxal-5â²-phosphate; CBS; Cystathionine β-synthase; 3-MST; 3-mercaptopyruvate sulfurtransferase; Nrf2; NFâ
Antioxidants and HNE in redox homeostasis
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; 15-LOX; 15-lipoxygenase; 4-HNE; 4-hydroxynonenal; AKRs; aldo-keto reductases; ALDHs; aldehyde dehydrogenases; AP-1; activator protein 1; ARE; antioxidant responsive element; Bcl-2; B-cell lymphoma 2; COX-2; cyclooxygenase-2; DHN; 1,4-dihydroxy-2-nonene;
Astrocyte elevated gene-1 (AEG-1) and the A(E)Ging HIV/AIDS-HAND
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Astrocytes; Aging; HIV-associated neurocognitive disorders; Neuroinflammation; ER/Nucleolar/Oxidative stress; Excitotoxicity; Aβ; amyloid beta; AEG-1; astrocyte elevated gene-1; AD; Alzheimer's disease; AIDS; acquired immune deficiency syndrome; ARE; a
Anti-inflammatory effect of strawberry extract against LPS-induced stress in RAW 264.7 macrophages
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Strawberry; Phenolic compounds; LPS; Inflammation; ROS; Prevention; 2,4 DNP; 2,4-Dinitrophenol; ACYs; anthocyanins; ARE; antioxidant responsive element; CDNB; 1-chloro-2,4-dinitro benzene; DMEM; Dulbecco's Modified Eagle Medium; DPPH; 2,2-DiPhenyl-1-Picry
Silibinin Inhibits Proliferation and Migration of Human Hepatic Stellate LX-2 Cells
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AKR1C1; aldo-keto reductase family 1, member C1; ARE; antioxidant responsive element; CDKI; cyclin dependent kinase inhibitor; CYP450; cytochrome P450; DMSO; dimethylsulphoxide; DMEM; Dulbecco's modified Eagle's medium; ECM; extracellular matrix; FBS; fet
Research reportDapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ADC; apparent diffusion coefficient; ARE; Antioxidant responsive element; ATP; Adenosine Triphosphate; DAHK; L-Asp-Ala-His-Lys; DCF; 2â²,7â²-dichlorofluorescein; DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DTI; Diffusion Tensor Imaging; DWI
Dietary Foeniculum vulgare Mill extract attenuated UVB irradiation-induced skin photoaging by activating of Nrf2 and inhibiting MAPK pathways
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Foeniculum vulgare Mill; UVB; Matrix metalloproteinases; Collagen; AP-1; Activated protein 1; ARE; Antioxidant responsive element; CCD; Charge-coupled device; ECM; Extracellular matrix; ERK; Extracellular signal-regulated kinase; FV; Foeniculum vulgare Mi
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ALI; acute lung injury; APCs; antigen-presenting cells; ARE; antioxidant responsive element; Bach1; Broad complex-Tramtrack-Bric-a-brac (BNB) and Cap'n'collar (CNC) homolog 1; BAL; bronchoalveolar lavage; BR; bilirubin-IXα; BV; biliverdin-IXα; BVR;
Pterostilbene-mediated Nrf2 activation: Mechanistic insights on Keap1:Nrf2 interface
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; PTS; pterostilbene; ARE; antioxidant responsive element; Keap1; Kelch-like ECH-associated protein-1; Nrf2; nuclear factor erythroid 2-related factor 2; MIN6 cells; mouse insulinoma-6 cells; MD; molecular dynamics; RMSD; root-mean square deviation; MM-GBSA
Heme oxygenase-1-derived bilirubin counteracts HIV protease inhibitor-mediated endothelial cell dysfunction
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; PI; protease inhibitors; ROS; reactive oxygen species; HO-1; heme oxygenase-1; CO; carbon monoxide; CORM2; carbon monoxide releasing molecule-2; iCORM2; inactivated carbon monoxide releasing molecule-2; CM-H2DCFDA; 5-(and-6)-chloromethyl-2,7-dichlorodihyd
3-Hydro-2,2,5,6-tetramethylpyrazine: A novel inducer of zinc transporter-1 in HepG2 human hepatocellular carcinoma cells
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ARE; antioxidant responsive element; DHPs; dihydropyrazines; DHP-3; 3-hydro-2,2,5,6-tetramethylpyrazine; D-MEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; MRE; metal responsive element; MTF-1; metal-responsi
Targeting thioredoxin-1 with siRNA exacerbates oxidative stress injury after cerebral ischemia/reperfusion in rats
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ANOVA; analysis of variance; ARE; antioxidant responsive element; CV; Cresyl Violet; I/R; ischemia/reperfusion; MCA; middle cerebral artery; MCAO; middle cerebral artery occlusion; MDA; malondialdehyde; MEFs; mouse embryo fibroblasts; Nrf2; nuclear factor
Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Nrf2/ARE activators; Oxime-bearing coumarins; Antioxidant activity; Cytoprotection; ABCC3; ATP-binding cassette, subfamily C, member 1; AKR1C1; aldo-keto reductase 1 subunit C-1; AKR1C2; aldo-keto reductase 1 subunit C-2; AKR1C3; aldo-keto reductase 1 sub
The involvement of p62-Keap1-Nrf2 antioxidative signaling pathway and JNK in the protection of natural flavonoid quercetin against hepatotoxicity
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Quer; quercetin; Cliv; clivorine; APAP; acetaminophen; CCl4; carbon tetrachloride; TSN; toosendanin; Nrf2; nuclear factor erythroid 2-related factor 2; ARE; antioxidant responsive element; Keap1; kelch-like ECH-associated protein-1; GCLC; catalytic subuni
Correlation and functional differentiation between different markers to study the genetic diversity analysis in medicinally important plant Plumbago zeylanica
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Plumbago zeylanica; Genetic diversity; Phylogenetic analysis; SSR; SRAP; ITS; AFLP:; Amplified Fragment Length Polymorphism; AMOVA:; Analysis of molecular variance; ARE:; Antioxidant responsive element; CTAB:; Cetyl trimethylammonium bromide; dNTPs:; Deox
Cyanidin-3-O-glucoside modulates intracellular redox status and prevents HIF-1 stabilization in endothelial cells in vitro exposed to chronic hypoxia
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ARE; antioxidant responsive element; C3G; cyanidin-3-O-glucoside; HIF-1; hypoxia inducible factor-1; HO-1; heme oxygenase-1; HUVECs; human umbilical vein endothelial cells; MMP; matrix metalloproteinase; NQO-1; NAD(P)H:quinone oxidoreductase; Nrf2; NF-E2-
Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells - up regulation of Nrf2 expression and down regulation of NF-κB and COX-2
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ANOVA; Analysis of variance; AO/EB; Acridine orange/ethidium bromide; ARE; Antioxidant responsive element; [Ca2Â +]i; Intracellular calcium level; CAT; Catalase; CCCP; Carbonyl cyanide m-chlorophenylhydrazone; COX-2; Cyclooxygenase-2; CBMN; Cytokinesis bl
The H+-ATP synthase: A gate to ROS-mediated cell death or cell survival
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AIF; apoptosis inducing factor; Akt; v-Akt murine thymoma viral oncogene; AP-1; activator protein 1; ARE; antioxidant responsive element; ASK1; apoptosis signal-regulated kinase 1; ATM; ataxia telangiectasia mutated; Duox; Dual oxidase enzymes; DUSP3; dua
Posttranslational mechanisms modulating the expression of the cytochrome P450 1A1 gene by methylmercury in HepG2 cells: A role of heme oxygenase-1
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AhR; aryl hydrocarbon receptor; MeHg; methyl mercury chloride; CYPs; cytochrome P450s; HO-1; heme oxygenase-1; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD); XRE; xenobiotic responsive element; ARE; antioxidant responsive element; SnMP; Tin mesoporphyr
Ochratoxin-induced toxicity, oxidative stress and apoptosis ameliorated by quercetin - Modulation by Nrf2
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ANOVA; analysis of variance; AO/EB; acridine orange/ethidium bromide; ARE; antioxidant responsive element; [Ca2+]i; intracellular calcium level; CAT; catalase; CCCP; carbonyl cyanide m-chlorophenylhydrazone; CBMN; cytokinesis block micronucleus assay; DAB
Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ALAS 1; delta-aminolevulinate synthase 1; ARE; antioxidant responsive element; BVR; biliverdin reductase; tBH; tert-butyl hydroquinone; CA; carnosol; CAA; carnosic acid; CoPP; cobalt protoporphyrin IX; CO-RMs; carbon monoxide-releasing molecules; DHC; 2,2
Punctum on two different transcription factors regulated by PGC-1α: Nuclear factor erythroid-derived 2-like 2 and nuclear respiratory factor 2
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; γGCS; gamma-glutamylcysteine synthetase; ARE; antioxidant responsive element; BAT; brown adipose tissue; CNC; Cap 'n' collar; COX; cytochrome c oxidase; CR; calorie restriction; CREB; cAMP response element-binding protein; ERRs; Estrogen-related rece
Redox signaling loops in the unfolded protein response
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AGR2; anterior gradient 2; ARE; antioxidant responsive element; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; ASK1; apoptosis signal-regulating kinase-1; BI-1; BAX inhibitor-1; BiP; immunoglobulin heavy chain-binding pr
Induction of quinone oxidoreductase 1 enzyme by Rhazya stricta through Nrf2-dependent mechanism
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Act-D; Actinomycin D; AhR; Aryl hydrocarbon receptor; ARE; Antioxidant responsive element; CYP; Cytochrome P450; Gapdh; Glyceraldehyde-3-phosphate dehydrogenase; MTT; (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide); Nqo1; NAD(P)H:quinone o
Redox-regulating role of insulin: The essence of insulin effect
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; 4-HNE; 4-hydroxynonenal; 8-OHdG; 8-hydroxydeoxyguanosine; 8-OHG; 8-hydroxyguanine; 8-iso-PGF2α; 8-iso-prostaglandin F2α; AD; Alzheimer's disease; AIDS; acquired immunodeficiency syndrome; Akt; protein kinase B; AMI; acute myocardial infarction; APS; a
Cellular adaptive response to glutathione depletion modulates endothelial dysfunction triggered by TNF-α
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Adaptive response; Nrf2; Oxidative stress; Antioxidant Responsive Element; Endothelial dysfunction;
Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; ARE; antioxidant responsive element; DEM; diethylmaleate; IL-1β; interleukin-1 beta; Keap1; Kelch-like ECH-associated protein 1; LMB; leptomycin B; Nrf2; NF-E2-related factor 2; PMA; phorbol 12-myristate 13-acetate; tBHQ; tert-butyl hydroxyquinone; TNFα
Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Aβ; beta-amyloid; AD; Alzheimer's disease; Apaf-1; apoptosis activating factor-1; APP; beta-amyloid precursor protein; ARE; antioxidant responsive element; DCF; 2â²,7â²-dichlorofluorescin; DCFH-DA; 2â²,7â²-dichlorofluorescin diacetate; EB; ethidium b
Down-regulation of the detoxifying enzyme NAD(P)H:quinone oxidoreductase 1 by vanadium in Hepa 1c1c7 cells
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Act-D; actinomycin D; AhR; aryl hydrocarbon receptor; ARE; antioxidant responsive element; c12; AhR-deficient Hepa 1c1c7 cells; CHX; cycloheximide; DMSO; dimethylsulfoxide; EMSA; Electrophoretic mobility shift assay; Hepa 1c1c7; murine hepatoma Hepa 1c1c7
Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; Peroxynitrite; Heme oxygenase; NF-E2-related factor 2; Antioxidant responsive element; Akt; Apoptosis; PC12 cells; Free radicals
Redox regulation of the transcriptional repressor Bach1
Keywords: عنصر پاسخ دهنده آنتی اکسیدان; AP-1; activator protein-1; ARE; antioxidant responsive element; Bach1; BTB and CNC homology; bZIP; basic leucine zipper; CNC; Cap'n'Collar; EMSA; electrophoretic mobility shift assay; GCS; γ-glutamylcysteine synthetase; GFP; green fluorescent protein