دانلود مقالات ISI درباره oligonucleotide antisense + ترجمه فارسی

Chemically modified oligonucleotides with efficient RNase H response

Keywords: oligonucleotide antisense; RNase H cleavage; Antisense oligonucleotide; Antisense technology; Modified nucleotide; Modified oligonucleotide;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Establishing chitosan coated PLGA nanosphere platform loaded with wide variety of nucleic acid by complexation with cationic compound for gene delivery

Keywords: oligonucleotide antisense; Poly(d,l-lactide-co-glycolide); Nanosphere; Chitosan; Emulsion solvent diffusion method; pDNA; Antisense oligonucleotide; siRNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Upregulation of PEDF expression by PARP inhibition contributes to the decrease in hyperglycemia-induced apoptosis in HUVECs

Keywords: oligonucleotide antisense; Poly(ADP-ribose)polymerase; Angiogenesis; Vascular endothelium growth factor; Pigment epithelium-derived factor; p38 MAP kinase; Apoptosis; Antisense oligonucleotide

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Antisense oligonucleotide Elk-1 suppresses the tumorigenicity of human hepatocellular carcinoma cells

Keywords: oligonucleotide antisense; Elk-1; Hepatocellular carcinoma; Protein kinase C alpha; Tumorigenesis; Antisense oligonucleotide;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Incorporation of positively charged ribonucleic guanidine linkages into oligodeoxyribonucleotides: Development of potent antisense agents

Keywords: oligonucleotide antisense; Ribonucleic guanidine (RNG); RNG/DNA chimera; Antisense oligonucleotide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Microinjection into cultured hippocampal neurons: A straightforward approach for controlled cellular delivery of nucleic acids, peptides and antibodies

Keywords: oligonucleotide antisense; Microinjection; Neuron; RNAi; Antisense oligonucleotide; Antibody; Fusion protein; Peptide;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Knockdown of Acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Apolipoprotein B; Triacylglycerol synthesis; Acyl-CoA:diacylglycerol acyltransferase; VLDL secretion; Obesity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: An antisense study

Keywords: oligonucleotide antisense; muscarinic receptor; analgesia; type 1 ryanodine receptors; type 2 ryanodine receptors; type 3 ryanodine receptors; intracellular Ca2+; aODN; antisense oligonucleotide; DAG; diacylglycerol; dODN; degenerated oligonucleotide; InsP3; inositol-1,4,5-triphosp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown

Keywords: oligonucleotide antisense; Antidepressant; Heparin; Knockdown mice; Inositol-1,4,5-trisphosphate receptor; Intracellular calcium; aODN; antisense oligonucleotide; i.c.v.; intracerebroventricular; InsP3Rl; type 1 inositol-1,4,5-trisphosphate receptor; InsP3R2; type 2 inositol-1,4,5-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Gap junctions; Rat; Compression; Transection; Astrocytes; Glial fibrillary acidic protein; Microglia; Activation; Neutrophils; Vascular endothelial cells; Vascular permeability; Behavioural testing

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Suppression of ClC-3 channel expression reduces migration of nasopharyngeal carcinoma cells

Keywords: oligonucleotide antisense; ClC-3; Chloride channels; Antisense oligonucleotide; Cell migration; Cell volume

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Adenoviral-mediated inhibition of connective tissue growth factor in Rat-2 cells

Keywords: oligonucleotide antisense; CTGF; TGF-β; Adenovirus; Antisense oligonucleotide; Rat-2 fibroblasts;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Lipoplex and peptide-based strategies for the delivery of steric-block oligonucleotides

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Splice correction; Lipoplex; Cell penetrating peptide

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats

Keywords: oligonucleotide antisense; Paraquat; Antisense oligonucleotide; Heat shock protein 47; Pulmonary fibrosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Mediation of burn-induced hypermetabolism by CRF receptor-2 activity

Keywords: oligonucleotide antisense; Antisense oligonucleotide; CRF receptor antagonist; Urocortin; Intraventricular injection; Energy expenditure;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells

Keywords: oligonucleotide antisense; Brain tumours; Novel therapies; Antisense oligonucleotide; Rhabdoid tumour

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Non-viral gene therapy for Duchenne muscular dystrophy: Progress and challenges

Keywords: oligonucleotide antisense; AON, antisense oligonucleotide; BMD, Becker muscular dystrophy; DMD, Duchenne muscular dystrophy; ODN, oligodeoxynucleotides; RDO, RNA/DNA chimeric oligonucleotideMuscular dystrophy; Dystrophin; Antisense oligonucleotide; Plasmid gene therapy; Gene editin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Detection of HDM2 and VEGF co-expression in cancer cell lines: novel effect of HDM2 antisense treatment on VEGF expression

Keywords: oligonucleotide antisense; HDM2; VEGF; Co-expression; Antisense oligonucleotide; Cancer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Viral-mediated gene therapy for the muscular dystrophies: Successes, limitations and recent advances

Keywords: oligonucleotide antisense; Dystrophin; Utrophin; Adeno-associated virus; Exon skipping; Antisense oligonucleotide

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2007 سفارش ترجمه

Involvement of Egr-1 in lens epithelial cell death induced by selenite

Keywords: oligonucleotide antisense; lens epithelial cell; Egr-1; selenite; cell death; antisense oligonucleotide

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

C-Met antisense oligodeoxynucleotide inhibits growth of glioma cells

Keywords: oligonucleotide antisense; HGF; hepatocyte growth factor; c-Met; hepatocyte growth factor receptor; ASODN; antisense oligonucleotide; ODNs; oligodexynucleotides; NSODN; nonsense oligonucleotide; FCM; flow cytometry; MTT; methyl thiazole tetrazolium; FAM; caroboxyfluorescein-5-succi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Enhanced cellular binding of concatemeric oligonucleotide complexes

Keywords: oligonucleotide antisense; DMEM, Dulbecco's modified Eagle's medium; PAAG, polyacrylamide gel; PAGE, polyacrylamide gel electrophoresisOligonucleotide complex; Oligonucleotide delivery; Cellular uptake; Antisense oligonucleotide

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Wound repair and proliferation of bronchial epithelial cells enhanced by bombesin receptor subtype 3 activation

Keywords: oligonucleotide antisense; BRS-3; bombesin receptor subtype 3; AHR; airway hyperresponsiveness; BECs; bronchial epithelium cells; ASO; antisense oligonucleotide; ISH; in situ hybridization; Bombesin receptor subtype 3 (BRS-3); Airway hyperresponsiveness (AHR); Bronchial epithelium

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Mcl-1 overexpression in hepatocellular carcinoma: A potential target for antisense therapy

Keywords: oligonucleotide antisense; HCC; Mcl-1; Targeted therapy; Antisense oligonucleotide

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Antisense oligonucleotide targeting c-fos mRNA limits retinal pigment epithelial cell proliferation; a key step in the progression of proliferative vitreoretinopathy

Keywords: oligonucleotide antisense; gene therapy; c-fos; antisense oligonucleotide; proliferative vitreoretinopathy; retinal pigment epithelium;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Synthesis of oligonucleoside phosphorodithioates on a solid support by the H-phosphonothioate method

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Oligonucleoside phosphorodithioates; H-Phosphonothioate method;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Phase II study of PKC-α antisense oligonucleotide aprinocarsen in combination with gemcitabine and carboplatin in patients with advanced non-small cell lung cancer

Keywords: oligonucleotide antisense; Aprinocarsen; Combination therapy; Advanced non-small cell lung cancer; Gemcitabine; Carboplatin; Phase II; Antisense oligonucleotide; Affinitak; ISIS; LY900003

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells

Keywords: oligonucleotide antisense; Survivin; Radiosensitivity; Antisense oligonucleotide;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Efficient delivery of a Bcl-2-specific antisense oligodeoxyribonucleotide (G3139) via transferrin receptor-targeted liposomes

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Transferrin; Bcl-2; Liposomes; Leukemia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

N-terminal acylation of the SV40 nuclear localization signal peptide enhances its oligonucleotide binding and membrane translocation efficiencies

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Acylated peptides; Attenuated total reflection FTIR; Atomic force microscopy; Cell translocation; Circular dichroism; Epifluorescence; Nuclear localization signal peptide

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

PKCα expression regulated by Elk-1 and MZF-1 in human HCC cells

Keywords: oligonucleotide antisense; PKCα; Elk-1; MZF-1; Transcription regulation; Antisense oligonucleotide

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Type II/III Runx2/Cbfa1 is required for tooth germ development

Keywords: oligonucleotide antisense; Runx2/Cbfa1; Isoform; Antisense oligonucleotide; Tooth germ development; Organ culture

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Comparison of basic peptides- and lipid-based strategies for the delivery of splice correcting oligonucleotides

Keywords: oligonucleotide antisense; Antisense oligonucleotide; PNA; Delivery; Cell penetrating peptide; Liposome; Splicing correction

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Real-time detection and efficacy of antisense oligonucleotides delivered by PAMAM dendrimers in living cells

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Molecular beacon; PAMAM dendrimer;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Determination of GTI-2040, a novel antisense oligonucleotide, in human plasma by using HPLC combined with solid phase and liquid-liquid extractions

Keywords: oligonucleotide antisense; Antisense oligonucleotide; GTI-2040; Solid-phase extraction;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

S100A4 antisense oligodeoxynucleotide suppresses invasive potential of neuroblastoma cells

Keywords: oligonucleotide antisense; Neuroblastoma; S100A4; Invasion; Antisense oligonucleotide; MMP-2;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Basal adrenocorticotropin (ACTH) secretion is negatively modulated by protein phosphatase 5 in mouse pituitary corticotropin AtT20 cells

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Adrenocorticotropic hormone; Dexamethasone; POMC; CRF;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Identification of a novel protein for memory regulation in the hippocampus

Keywords: oligonucleotide antisense; Negative memory regulation; Hippyragranin; Spatial memory; LTP; Antisense oligonucleotide;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Small interfering RNA; Urokinase-type plasminogen activator receptor; Oral squamous cell carcinoma;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Synergistic down-regulation of telomerase by all-trans retinoic acid and antisense oligonucleotide in oral squamous cell carcinoma cell line (Tca8113)

Keywords: oligonucleotide antisense; All-trans retinoid acid; Telomerase; Antisense oligonucleotide; Oral squamous cell carcinoma;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Targeting delivery of oligonucleotide and plasmid DNA to hepatocyte via galactosylated chitosan vector

Keywords: oligonucleotide antisense; Galactosylated low molecular weight chitosan; Plasmid DNA; Antisense oligonucleotide; Hepatocyte targeting; Transfection efficiency; Non-viral vector;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Central administration of small interfering RNAs in rats: A comparison with antisense oligonucleotides

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Food intake; Melanocortin; Small interfering RNA; (Rat);

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibiting BDNF expression by antisense oligonucleotide infusion causes loss of nigral dopaminergic neurons

Keywords: oligonucleotide antisense; Brain derived neurotrophic factor; Antisense oligonucleotide; Dopaminergic neurons; Substantia nigra; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Aβ region of amyloid precursor protein

Keywords: oligonucleotide antisense; Disorders of the nervous system; Degenerative disease: Alzheimer's - beta amyloid; Proteomic identification; SAMP8; Amyloid precursor protein; Antisense oligonucleotide; Amyloid beta-peptide; Alzheimer's disease; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

NAPOR-3 RNA binding protein is required for apoptosis in hippocampus

Keywords: oligonucleotide antisense; Development and regeneration; Neuronal death; Ischemic injury; Apoptosis; Rat organotypic hippocampal slice; Antisense oligonucleotide;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

The role of the N-methyl-d-aspartate receptor in ketamine-induced apoptosis in rat forebrain culture

Keywords: oligonucleotide antisense; NMDA receptor; ketamine; antagonist; antisense oligonucleotide; neurodegeneration; apoptosis; AMPA; dl-α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; d-APV; 2-d-l-aminophosphonovaleric acid; DMEM; Dulbe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

A type II ribonuclease H from Leishmania mitochondria: An enzyme essential for the growth of the parasite

Keywords: oligonucleotide antisense; MLS; Mitochondrial localization signal; LRNase HIIC; Leishmania mitochondrial RNase HII precursor form; LRNase HIICΔMLS; Leishmania mitochondrial RNase HII mature form lacking the MLS; kDNA; kinetoplast DNA; PMSF; phenylmethylsulfonyl fluoride; IPTG; iso

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Bcl-2 inhibitors potentiate the cytotoxic effects of radiation in Bcl-2 overexpressing radioresistant tumor cells

Keywords: oligonucleotide antisense; Antisense oligonucleotide; Apoptosis; Bcl-2; Radiosensitizer; Tetrocarcin A;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Cyclosporin A inhibits the early phase of NF-κB/RelA activation induced by CD28 costimulatory signaling to reduce the IL-2 expression in human peripheral T cells

Keywords: oligonucleotide antisense; CsA; cyclosporin A; HPTC; human peripheral T cells; Antisense oligonucleotide; Costimulation; Nuclear factor of activated T cells; Nuclear factor-κB; Signal transduction; T lymphocytes;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Peroxide-Mediated Desulfurization of Phosphorothioate Oligonucleotides and Its Prevention

Keywords: oligonucleotide antisense; antisense oligonucleotide; stability; polyethylene glycol; antioxidant; formulation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه