
The effect of sulfonate leaving groups on the hypoxia-selective toxicity of nitro analogs of the duocarmycins
Keywords: ضد تومور; CBI; seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one; DIPEA; diisopropylethylamine; DMA; dimethylacetamide; EDCI·HCl; N-ethyl-Nâ²-(3-dimethylaminopropyl)carbodiimide hydrochloride; HCR; hypoxic cytotoxicity ratio; TMI; 5,6,7-trimethoxyindole; Cy