Effects of hippuristanol, an inhibitor of eIF4A, on adult T-cell leukemia
Keywords: ATL; Hippuristanol; NF-kappaB; AP-1; eIF4A;
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Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans
Keywords: Pa-EE; ethanol extract of Phaseolus angularis; LPS; lipopolysaccharide; NO; nitric oxide; PG; prostaglandin; iNOS; inducible NO synthase; COX; cyclooxy-genase; IL; interleukin; IKK; I (B) kinase; Akt; protein kinase B; PDK; phosphoinositide-dependent kina
c-Jun and c-Fos regulate the complement factor H promoter in murine astrocytes
Keywords: CFH; complement factor H; MBL; mannose-binding lectin; kDa; kiloDalton; CNS; central nervous system; Ast 2.1; cell line astrocyte 2.1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; RACE; rapid amplification of cDNA ends; IFN-γ; interferon-gamma; TNF-Î
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3
Keywords: Nuclear receptors; Hepatocellular carcinoma; Cell cycle; Liver hyperplasia; AP-1; activating protein-1; PH; partial hepatectomy; JNK; c-jun-N-terminal kinase; HCC; hepatocellular carcinoma; PPAR-α; peroxisome proliferator-activated receptor-alpha; TCPOBO
Rapid, cell-based toxicity screen of potentially therapeutic post-transcriptional gene silencing agents
Keywords: post-transcriptional gene silencing; high throughput screening; AP-1; activator protein; CNV; choroidal neovascularization; CRE; cyclic AMP response element; DMEM/F12; Dulbecco's modified essential medium; dsRNA; double stranded RNA; HEK293S; human embr
Regulation of human papillomavirus type 16 early gene expression in trophoblastic and cervical cells
Keywords: HPV; Papillomavirus; Transcription; Replication; E2; Early proteins; AP-1; Steroids; Cervical; Trophoblast;
Phosphorylated c-Jun and Fra-1 induce matrix metalloproteinase-1 and thereby regulate invasion activity of 143B osteosarcoma cells
Keywords: AP-1; activator protein-1; CXCR4; C-X-C chemokine receptor type 4; ECM; extracellular matrix; ELISA; enzyme-linked immunosorbent assay; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; ETS; E-twenty six; FCS; fet
δEF1 promotes osteolytic metastasis of MDA-MB-231 breast cancer cells by regulating MMP-1 expression
Keywords: δEF1; MMP-1; AP-1; Breast cancer; Bone metastasis
NFAT regulates pre-synaptic development and activity-dependent plasticity in Drosophila
Keywords: NFAT; Nuclear Factor of Activated T-cells; NMJ; Neuromuscular junction; EJC; Evoked Junctional Current; RHD; Rel-homology domain; AP-1; Activating Protein-1; MAP1B; Microtubule associated protein 1B; FasII; Fasciclin II; Drosophila; NFAT; Plasticity; Syna
Noradrenergic regulation of period1 expression in spinal astrocytes is involved in protein kinase A, c-Jun N-terminal kinase and extracellular signal-regulated kinase activation mediated by α1- and β2-adrenoceptors
Keywords: astrocyte; noradrenaline; clock gene; Per1; spinal cord; AP-1; activator protein 1; CREB; cAMP, response element binding protein; CRY; Cryptochrome; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase; MAPKs; mitogen-activated protein
Transient Receptor Potential Vanilloid 4 Activated Inflammatory Signals by Intestinal Epithelial Cells and Colitis in Mice
Keywords: IBD; Calcium Signaling; Intestinal Permeability; Immune Response; AP-1; activator protein 1; BSA; bovine serum albumin; DSS; dextran sodium sulfate; 4αPDD; 4α-phorbol-12,13-didecanoate; IL; interleukin; IP-10; interferon gamma-induced protein 10; KC;
Adaptive response to oxidative stress: Bacteria, fungi, plants and animals
Keywords: AHP1; alkylhydroperoxide reductase; AHR; aryl hydrocarbon receptor; ARE; antioxidant response element; 2CPA; 2-Cys peroxiredoxin-A; CRD; cysteine rich domain; Cul3; Cullin 3; DPH; diphenylhexatriene; EpRE; electrophile response element; ERK; extracellular
Old and new generation lipid mediators in acute inflammation and resolution
Keywords: 5-HT; 5-hydroxytryptamine; HETEs; hydroxyeicosatetraenoic acids; 5-HEDH; 5-hydroxyeicosanoid dehydrogenase; 5(S)-HPETE; hydroperoxyeicosatetranoic acid; 15R-HETE; 15-R-hydroxyeicosatetraenoic acid; 17R-HDHA; 17R-hydroxydocosahexaenoic acid; AA; arachidoni
Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling
Keywords: ROS; reactive oxygen species; Nox; NADPH oxidase; O2â¢â; superoxide; RNS; reactive nitrogen species; â¢NO; nitric oxide; SOD; superoxide dismutase; NOS; nitric oxide synthase; GSH; glutathione; AngII; angiotensin II; PDGF; platelet-derived growth fact
Asthma translational medicine: Report card
Keywords: ACQ; asthma control questionnaire; AHR; airway hyper-responsiveness; AP-1; activator protein 1; APC; antigen-presenting cell; AQLQ; asthma quality-of-life questionnaire; BALF; bronchoalveolar lavage fluid; CTLA-4; cytotoxic T lymphocyte-associated antigen
Toward managing chronic rejection after lung transplant: The fate and effects of inhaled cyclosporine in a complex environment
Keywords: AP-1; activator protein-1 transcription factor; API; active pharmaceutical ingredient; BM; basement membrane; BALF; bronchoalveolar lavage fluid; BALT; broncho-associated lymphoid tissue; BCS; biopharmaceutical classification system; BOS; bronchiolitis ob
Arsenic-induced oxidative stress and its reversibility
Keywords: GSH; glutathione; GSSG; glutathione disulfide; NAC; N-acetylcysteine; ROS; reactive oxygen species; RNS; reactive nitrogen species; O2â¢â; superoxide anion; â¢OH; hydroxyl radical; 1O2; singlet oxygen; MMAV; monomethyl arsonate; MMAIII; monomethyl ars
ReviewInterleukin-6, a mental cytokine
Keywords: 6-AN; 6-aminonicotinamide; Aβ; amyloid β; AD; Alzheimer's disease; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; AP-1; activator protein 1; APP; amyloid precursor protein; BDNF; brain-derived neurotrophic factor; cAMP; cyclic adenosine monoph
A mutant selective anti-estrogen is a pure antagonist on EREs and AP-1 response elements
Keywords: Estrogen receptor; Estrogen response element; AP-1; SERM
Colon carcinogenesis: Learning from NF-κB and AP-1
Keywords: Colorectal cancer; Inflammation; Signal transduction; NF-κB; AP-1
Role of AP-1 and RE-1 binding sites in matrix metalloproteinase-2 transcriptional regulation in skeletal muscle atrophy
Keywords: Matrix metalloproteinase-2; Muscle atrophy; Extracellular matrix; Gene expression regulation; Transcription; AP-1
Synthesis and evaluation of quinazolinone derivatives as inhibitors of NF-κB, AP-1 mediated transcription and eIF-4E mediated translational activation: Inhibitors of multi-pathways involve in cancer
Keywords: Transcription factors; NF-κB; AP-1; Translational factor; eIF-4E; Quinazolinone derivatives; Molecular modeling; Thiazole derivatives
PKCθ is necessary for efficient activation of NFκB, NFAT, and AP-1 during positive selection of thymocytes
Keywords: Positive selection; PKCθ; NFκB; NFAT; AP-1;
AP-1 — The Jun proteins: Oncogenes or tumor suppressors in disguise?
Keywords: AP-1; JNK; c-Jun; JunB; JunD; Cancer
Lithocholic acid upregulates uPAR and cell invasiveness via MAPK and AP-1 signaling in colon cancer cells
Keywords: LCA; Erk-1/2; AP-1; uPAR; Colon cancer
Transactivation of human osteopontin promoter by human T-cell leukemia virus type 1-encoded Tax protein
Keywords: HTLV-1; Tax; Transactivation; Osteopontin; PI3K/AKT; AP-1
Remote Thermal Injury Increases LPS-Induced Intestinal IL-6 Production1
Keywords: IL-6; intestinal mucosa; burn; TLR-4; AP-1
Silencing MR-1 attenuates inflammatory damage in mice heart induced by AngII
Keywords: MR-1; Angiotensin II; NF-κB; AP-1; Myocardium inflammation
Synergistic Protection in Lung Ischemia-Reperfusion Injury With Calcineurin and Thrombin Inhibition
Keywords: AP-1; activator protein-1; aPTT; activated partial thromboplastin time; BAL; bronchoalveolar lavage; BSA; bovine serum albumin; CINC; cytokine-induced neutrophil chemoattractant; CPM; counts per minute; IL-1β; interleukin-1 beta; LIRI; lung ischemia-repe
Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner
Keywords: Augmenter of liver regeneration; Human hepatocytes; Liver regeneration; AKT/PKB; ERK1/2; Liver specificity; AP-1; activator protein-1; rhALR; recombinant human augmenter of liver regeneration; EGF; epidermal growth factor; ERK1/2; extracellular signal-reg
HTLV-1 Tax: Linking transformation, DNA damage and apoptotic T-cell death
Keywords: AP-1; activator protein 1; APC; anaphase promoting complex; ATL; adult T-cell leukemia; ATM kinase; ataxia telangiectasia mutated kinase; BES; base excision repair; Chk1; checkpoint kinase 1; Chk2; checkpoint kinase 2; CREB; cyclic AMP response element-bi
Human TMEM174 that is highly expressed in kidney tissue activates AP-1 and promotes cell proliferation
Keywords: AP-1; ELK1; TMEM174; Kidney; Cell proliferation
High affinity receptor for IgE stimulation activates protein kinase D augmenting activator protein-1 activity for cytokine producing in mast cells
Keywords: Mast cell; Protein kinase D; AP-1; IL-13; TNF-α; FcεRI
The anticancer effects of actinoporin RTX-A from the sea anemone Heteractis crispa (=Radianthus macrodactylus)
Keywords: Actinoporin; Anticancer activity; Inhibition of malignant transformation; Apoptosis; AP-1; NF-κB; p53 nuclear factorsINCC50, inhibition of number of colonies formed in soft agar C50; AP-1, activator protein-1; PFT, pore-forming toxins; EGF, epidermal grow
Gestational zinc deficiency affects the regulation of transcription factors AP-1, NF-κB and NFAT in fetal brain
Keywords: Zinc; Brain; Gestation; AP-1; NF-κB; NFAT
Dihydro-N-caffeoyltyramine down-regulates cyclooxygenase-2 expression by inhibiting the activities of C/EBP and AP-1 transcription factors
Keywords: Dihydro-N-caffeoyltyramine; Cyclooxygenase-2; CCAAT/enhancer-binding protein; AP-1
Inhibitory effect of 3-caffeoyl-4-dicaffeoylquinic acid from Salicornia herbacea against phorbol ester-induced cyclooxygenase-2 expression in macrophages
Keywords: 3-Caffeoyl-4-dicaffeoylquinic acid; Cyclooxygenase-2; CCAAT/enhancer-binding protein; AP-1
Calcium-dependent nitric oxide production is involved in the cytoprotective properties of n-acetylcysteine in glycochenodeoxycholic acid-induced cell death in hepatocytes
Keywords: Activator protein 1; AP-1; Anion superoxide; O2â; 2,7- dichlorofluorescein diacetate; DCFDA; (Z)-1-[2-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate; NONOate; dihydroethidium; DHE; glycochenodeoxycholic acid; GCDCA; reduced glutathione;
Herb medicine Gan-fu-kang attenuates liver injury in a rat fibrotic model
Keywords: Liver fibrosis; AP-1; PDGF-BB; MAPK; Type I collagen; Gan-fu-kang
Diosgenin inhibits macrophage-derived inflammatory mediators through downregulation of CK2, JNK, NF-κB and AP-1 activation
Keywords: Diosgenin; Antiinflammation; NF-κB; AP-1; CK2; JNK
Glutathione synthesis inhibitor butathione sulfoximine regulates ceruloplasmin by dual but opposite mechanism: Implication in hepatic iron overload
Keywords: Glutathione depletion; Gene regulation; Ceruloplasmin; Hepatic iron overload; AP-1; mRNA decay
17β-Estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ERα
Keywords: PS; pachytene spermatocytes; ERs; estrogen receptors; ERα; estrogen receptor α; ERβ; estrogen receptor β; E2; estradiol; GPR30; G-protein-coupled receptor-30; PPT; 4,4â²,4â³-(4-propyl-[1H]pyrazole-1,3,5-triyl) trisphenol; GAPDH; glyceraldehyde 3-pho
Piceatannol induces Fas and FasL up-regulation in human leukemia U937 cells via Ca2+/p38α MAPK-mediated activation of c-Jun and ATF-2 pathways
Keywords: Piceatannol; ERK; p38α MAPK; AP-1; Fas; FasL
Activating protein-1 family of transcription factors in the human placenta complicated by preeclampsia with and without fetal growth restriction
Keywords: Preeclampsia; FGR; Placenta; Jun; Fos; AP-1
Differential transcriptional regulation of IL-8 expression by human airway epithelial cells exposed to diesel exhaust particles
Keywords: DEP, diesel exhaust particles; PM, particulate matter; BEAS-2B cells, adenovirus 12SV40 hybrid virus transformed, non-tumorigenic human bronchial epithelial cells; HAEC, primary human airway epithelial cellsDiesel exhaust particle; IL-8; NFkB; AP-1; Trans
Quercetin attenuates Monocyte Chemoattractant Protein-1 gene expression in glucose primed aortic endothelial cells through NF-κB and AP-1
Keywords: MCP-1; Monocyte Chemoattractant Protein-1; HG; high glucose concentrations; AP-1; Activator Protein-1; NF-κB; Nuclear Factor-κB; RAECs; rat aortic endothelial cells; ROS; reactive oxygen species; HUVECs; human umbilical vein endothelial cells; NAC; N-ac
Glial cell line-derived neurotrophic factor induces cell migration and matrix metalloproteinase-13 expression in glioma cells
Keywords: GDNF; Migration; MMP-13; c-Jun; AP-1
The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor
Keywords: Trip6; Glucocorticoid receptor; Co-activator; NF-κB; AP-1; Transrepression
β-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes
Keywords: Na+–Ca2+ exchanger; β-Adrenergic pathway; CaMKII; AP-1; Chromatin immunoprecipitation; Cardiac hypertrophy; Heart failure
Inhibition of the JNK/AP-1 pathway reduces neuronal death and improves behavioral outcome after neonatal hypoxic–ischemic brain injury
Keywords: JNK MAP kinase; Neonatal hypoxia–ischemia; Neuroprotection; Apoptosis; Behavior; Transduction peptide; Smac/DIABLO; Calpain; AP-1; Inflammation