Keywords: AH; antioxidant; APAF-1; apoptotic protease activating factor 1; APE1; apurinic/apyrimidinic endonuclease 1; ARE; antioxidant response element; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; BCl; B-cell lymphoma family of cell death regu
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Keywords: EMF; electromagnetic field; NADH; nicotinamide adenine dinucleotide; ROS; reactive oxygen species; 8-OHdG; 8-hydroxy-2'-deoxyguanosine; RNS; reactive nitrogen species; TNF; tumour necrosis factor; PKC; protein kinase C; DR; death receptor; TNFR; TNF recep
Keywords: Apaf-1; Apoptotic protease-activating factor-1; A498; Renal proximal tubular carcinoma; BCA; Bicinchoninic acid; Bax; Bcl-2 associated X protein; Bcl-2; B-cell lymphoma 2; BSA; Bovine Serum Albumin; Cdc25; Cell-division control protein 25(Dual-Specificity
Keywords: Hydrogen sulphide; Stroke; Toxic effect; Neuroprotection; 3MST; 3-mercaptopyruvate sulfurtransferase; ADT; 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; AIF; apoptosis-inducing factor; Akt; protein kinase B; APAF-1; Apoptotic protease activating factor 1;
Keywords: Apaf-1; apoptotic protease activating factor-1; IL; intromission latency; ARE; antioxidant response element; INHB; inhibin B; Atg; autophagy-related genes; LH; luteinizing hormone; ABP; androgen-binding protein; LC3; light chain 3; CAT; catalase; ML; moun
Keywords: AMS; allyl methyl sulfide; AIF; apoptosis inducing factor; AKT; v-akt murine thymoma viral oncogene homolog; AP-1; activator protein-1; Apaf-1; apoptotic protease-activating factor-1; ASRK1; apoptosis signal-regulation kinase 1; COX-2; cyclooxygenase-2; C
Keywords: AHPP; 4-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine; Apaf-1; Apoptotic protease activating factor 1; AsnPhePhe; Asparagine-phenylalanine-phenylalanine; D-(Asp)8; D-Aspartic acid peptide; D; Degradable; E; Enzymatic degradation; H; Hydrolytic degradation; EDT
Keywords: â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: Aβ; beta-amyloid peptide; AAV; adeno-associated virus; ABAD; amyloid-beta-binding alcohol dehydrogenase; AD; Alzheimer's disease; ALP; autophagy-lysosome pathways; Apaf-1; apoptic protease-activating factor 1; APP; amyloid precursor protein; AICD; APP in
Keywords: Heat shock protein 27; Sea perch; Nervous necrosis virus; Apoptosis; Interferon; HSP; heat shock protein; RGNNV; red spotted grouper nervous necrosis virus; IFN; interferon; Cyto; cytochrome c; APAF-1; apoptotic protease activating factor-1; Bcl-2; B-cell
Keywords: PD; Parkinson's disease; AD; Alzheimer's disease; ROS; reactive oxygen species; SNpc; substantia nigra pars compacta; MnSOD; manganese superoxide dismutase; CuSOD; copper superoxide dismutase; NO; nitric oxide; O2â; superoxide anion; ONOOâ; peroxy
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; Apaf-1; apoptotic protease activating factor 1; CAD; caspase-activation DNase; cyt c; cytochrome c; Cy; cyclophilin; Drp-1; dynamin-related protein 1; ENDO; endonuclease; AIF; apoptosis-inducing
Keywords: ABCB1; ATP-Binding Cassette, Sub-Family B; MDR; Multi Drug Resistance; DAPK; Death Associated Protein Kinase; APAF-1; Apoptotic Peptidase Activating Factor 1; MLH1; MutL Homolog 1; MGMT; O-6-Methylguanine-DNA Methyltransferase; KDM5A; Lysine (K)-Specific
Keywords: ADI; acceptable daily intake; Apaf-1; apoptotic protease activating factor-1; ATF4; activating transcription factor 4; CHOP; C/EBP-homologous protein; eIF2α; eukaryotic initiation factor 2 alpha; ER; endoplasmic reticulum; G; ghrelin; GH; growth hormone;
Keywords: Algae; Apoptosis; Programmed cell death; Metacaspases; APAF-1; PARP-1;
Keywords: 3-HAA; 3-hydroxyanthranilic acid; 3-HKYN; 3-hydroxykynureanine; 5HT; 5-hydroxytryptamine; AIF; apoptosis-inducing factor; Apaf-1; apoptosis-activating factor 1; ATM; ataxia telangiectasia mutated; BAK; Bcl-2 antagonist killer; Bcl-2; B-cell lymphoma 2; Bc
Keywords: ASK1; apoptosis signal-regulating kinase; ALS; amyotrophic lateral sclerosis; Apaf-1; apoptotic protease-activating factor; ATF6; activating transcription factor 6; Atg12; autophagy-related gene 12; C9ORF72; chromosome 9 open reading frame 72; CHIP; carbo
Keywords: Preeclampsia; Oxidative stress; APAF-1; Ki-67
Keywords: Glycolysis; Cancer; Cell death; GAPDH; Hexokinase; ANT; adenine nucleotide translocase; APAF-1; apoptotic protease activating factor-1; ATG5; autophagy related 5; ATP; adenosine triphosphate; Bak; Bcl-2 homologous antagonistic killer; Bax; Bcl-2-associate
Keywords: EGFR-TKI; epidermal growth factor receptor tyrosine kinase inhibitor; MST; median survival time; HGF; hepatocyte growth factor; FISH; fluorescence in situ hybridization; PTEN; phosphatase and tensin homolog deleted from chromosome 10; PI3K; phosphoinositi
Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; AIF; apoptosis inducing factor; ANOVA; analysis of variance; APAf-1; apoptotic protease activating factor 1; Ara-c; cytosine arabinoside; BSA; bovine serum albumin; CREB; cyclic-AMP response element binding-pr
Keywords: AIF; apoptosis-inducing factor; AMPK; AMP kinase; Apaf-1; apoptotic protease activating factor; BMM; bone marrow-derived macrophages; cFLIP; cellular FLICE-like inhibitory protein; cIAP; cellular inhibitor of apoptosis protein; COX; cyclooxygenase; CTL; c
Keywords: AA; arachidonic acid; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease activating factor-1; ATP; adenosine triphosphate; ATP-ase; ATP synthase;
Keywords: AKT/PKB; protein kinase B; Apaf-1; apoptotic protease activating factor 1; ERK; extracellular signal-regulated kinase; ETC; electron transport chain; FADD; Fas-associated death domain; FOXO3a; forkhead-box protein O3a; HK; hexokinase; HNE-1; Na+/H+ exchan
Keywords: Aβ; amyloid-β peptides; APAF-1; apoptotic protease-activating factor-1; E2; 17β-estradiol; ER; estrogen receptor; ERβ; estrogen receptor β; ERE; estrogen responsive elements; HIF-1; hypoxia-inducible factor-1; mPTP; mitochondria permeability transiti
Keywords: ADCC; antibody dependent cell cytotoxicity; Apaf-1; apoptosis-activating factor 1; BID; BH3-interacting domain; CAD; caspase-activated DNase; CMV; cytomegalovirus; DC; dendritic cell; DLN; draining lymph node; FasL; Fas ligand; FADD; Fas-associated protei
Keywords: ABTS; 2,2â²-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); APAF-1; Apoptotic Protease Activating Factor-1; Apo1; Apoptosis Antigen 1; BAX; Bcl2-Associated X protein; Bcl2; B-cell lymphoma 2; BSA; Bovine Serum Albumin; BVc; Beta vulgaris cicla; BVr;
Mitochondrial apoptotic pathway mediated the Zn-induced lipolysis in yellow catfish Peteobagrus fulvidraco
Keywords: Zn; Apoptosis; Mitochondrial apoptotic pathway; Lipid metabolism; Low vertebrates; Apaf-1; apoptotic peptidase activating factor-1; ATGL; adipose TAG lipase; B2M; beta-2-microglobulin; Casp3a; caspase 3a; Casp3b; caspase 3b; Casp9; caspase 9; Cycs; cytoch
Insufficient Apaf-1 expression in early stages of neural differentiation of human embryonic stem cells might protect them from apoptosis
Keywords: Mitochondrial apoptosis; Neural differentiation; Human embryonic stem cell; Apaf-1;
VDAC1 functions in Ca2+ homeostasis and cell life and death in health and disease
Keywords: AIF; apoptosis inducing factor; ANT; adenine nucleotide translocase; APAF-1; apoptosis protease-activating factor 1; Bcl-2; B-cell lymphoma 2; CLL; chronic lymphocytic leukemia; CyP D; cyclophilin D; Cyto c; cytochrome c; HK; hexokinase; IMM; inner mitoch
Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems
Keywords: Apoptosis; Apaf-1; Split-luciferase; Truncated Apaf-1; Cell death; Apoptosome; Cell-free system;
Prognostic impact of Apaf-1, Cyclin D1, and AQP-5 in serous ovarian carcinoma treated with the first-line chemotherapy
Keywords: Serous ovarian carcinoma; Apaf-1; Cyclin D1; AQP-5; Immunohistochemistry; Chemotherapy;
ROS signalling in the biology of cancer
Keywords: AEJ; alternative end joining; ALL; acute lymphoblastic leukaemia; AML; acute myeloid leukaemia; Apaf-1; apoptotic protein activating factor 1; APL; acute promyelocytic leukaemia; ASK1; apoptosis signal regulating kinase 1; Bcr-Abl; breakpoint cluster-Abel
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Immature human DCs efficiently translocate endocytosed antigens into the cytosol for proteasomal processing
Keywords: Ag; antigen; Apaf-1; apoptotic protease-activating factor 1; APC; antigen presenting cell; CD; cluster of differentiation; DC; dendritic cell; GM-CSF; granulocyte-macrophage colony-stimulating factor; HLA; human leukocyte antigen; iDC; immature dendritic
Hydrogen sulfide in stroke: Protective or deleterious?
Keywords: Hydrogen sulphide; Stroke; Toxic effect; Neuroprotection; 3MST; 3-mercaptopyruvate sulfurtransferase; ADT; 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; AIF; apoptosis-inducing factor; Akt; protein kinase B; APAF-1; Apoptotic protease activating factor 1;
Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-κB pathway and anti-apoptotic Bcl-2
Keywords: AIF; Apoptosis inducing factor; ANT; Mitochondrial inner membrane protein adenine nucleotide translocase; Apaf-1; Apoptotic protease activating factor 1; BAG3; Bcl-2-associated athanogene domain 3; Bcl-2; B-cell lymphoma-2; HHE; 4-hydroxyhexenal; HNE; 4-H
Attribution of Bax and mitochondrial permeability transition pore on cantharidin-induced apoptosis of Sf9 cells
Keywords: CTD; cantharidin; PP2A; protein phosphatase type 2A; C; cytochrome C; Apaf-1; apoptotic protease activating facter-1; MPTP; mitochondrial membrane permeability transition pore; MMP; mitochondrial membrane potential; CsA; cyclosporin A; BCB; Bax channel bl
MiR-484 promotes non-small-cell lung cancer (NSCLC) progression through inhibiting Apaf-1 associated with the suppression of apoptosis
Keywords: NSCLC; MiR-484; Apaf-1; Migration and proliferation; Apoptosis;
Methylarginines within the RGG-Motif Region of hnRNP A1 Affect Its IRES Trans-Acting Factor Activity and Are Required for hnRNP A1 Stress Granule Localization and Formation
Keywords: Apaf-1; apoptotic protease activating factor 1; Bcl-xL; B-cell lymphoma extra large; CNBP; cellular nucleic acid binding protein; FGF2; fibroblast growth factor 2; G3BP1; Ras GTPase-activating protein-binding protein 1; IRES; internal ribosome entry site;
G2/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph3PAu[SC(OR)Â =Â NPh], RÂ =Â Me, Et, and iPr, during zebrafish development
Keywords: Annexin V-FITC; Recombinant annexin V conjugated to fluorescein isothiocyanate; APAF-1; Apoptotic protease activating factor 1; ATR; Ataxia telangiectasia and Rad3-related; Bax; Apoptosis regulator; Bcl-2; B-cell lymphoma 2; BIRC-5; Baculoviral inhibitor
BH3-only protein BIM: An emerging target in chemotherapy
Keywords: A1; Bcl-2-related protein A1; Apaf-1; Apoptotic protease-activating factor 1; ASK1; Apoptosis Signal Regulated Kinase 1; Bad; Bcl-2 associated agonist of cell death; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell l
Phorate induced oxidative stress, DNA damage and differential expression of p53, apaf-1 and cat genes in fish, Channa punctatus (Bloch, 1793)
Keywords: Phorate; SOD; p53; apaf-1; cat; micronuclei;
The translocator protein (18Â kDa) and its role in neuropsychiatric disorders
Keywords: 3α-HSD; 3α-hydroxysteroid dehydrogenase; 3β-HSD; 3β-hydroxysteroid dehydrogenase/Î5âÎ4; AIF; apoptosis inducing factor; AD; Alzheimer's disease; ANT; adenine nucleotide translocator; AP-1; activator protein 1; APAF-1; apoptotic peptidase activat
The fungicide thiabendazole causes apoptosis in rat hepatocytes
Keywords: APAF-1; apoptosis protease activating factor-1; CYP; cytochrome P450; DISC; death inducing signaling complex; EROD; ethoxyresorufin-o-deethylase; FADD; Fas-associated death domain; FBS; fetal bovine serum; FCCP; carbonylcyanide p-trifluoromethoxyphenylhyd
Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells
Keywords: A2780WT; drug-sensitive human ovarian cancer cells; A2780CisR; cisplatin resistant A2780 cells; ABC; ATP-binding cassette; Ano6; Anoctamin 6; Apaf-1; apoptotic protease activating factor 1; Atox1; Antioxidant 1 copper chaperone; AP; alkaline phosphatase;
Involvement of the extrinsic and intrinsic pathways in ultraviolet B-induced apoptosis of corneal epithelial cells
Keywords: Apoptosis; Cornea; Corneal epithelium; Potassium channels; Caspase; Apaf-1; Tear film;
Clausenidin from Clausena excavata induces apoptosis in hepG2 cells via the mitochondrial pathway
Keywords: RPMI; Rosewell Park Memorial Institute; HepG2; liver hepatocellular carcinoma; DNA; Deoxyribonucleic acid; DMSO; Dimethyl sulfoxide; JNK; c-Jun N-terminal kinases; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide; Apaf-1; Apoptotic protea
Role of the salt bridge between glutamate 546 and arginine 907 in preservation of autoinhibited form of Apaf-1
Keywords: Apaf-1; apoptotic protease activating factor-1; CARD; caspase recruitment domain; NOD; nucleotide-binding and oligomerization domain; WRD; WD40-repeat domain; NBD; nucleotide-binding domain; HD1; helical domain 1; WHD; winged-helix domain; HD2; helical do
MicroRNA-17-mediated down-regulation of apoptotic protease activating factor 1 attenuates apoptosome formation and subsequent apoptosis of cardiomyocytes
Keywords: Apaf-1; Cardiomyocytes; Apoptosome; miR-17;