Keywords: Apaf1; apoptotic peptidase activating factor 1; Casp7; caspase-7; Ccnd2; Cyclin D2; Cdc20; cell division cycle 20 homolog; IEC; intestinal epithelial cells; Kdr; kinase insert domain receptor; Pten; phosphatase and tensin homolog; Mcm2; minichromosome mai
مقالات ISI (ترجمه نشده)
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Keywords: ABCA1; ATP-binding cassette 1; AGEs; advanced glycation end products; AIF; apoptosis inducing factor; ALDH; aldehyde deshydrogenase; ANT; adenine nucleotide translocator; APAF1; apoptosis protease-activating factor-1; apoB; apolipoprotein B; ARE; antioxid
Keywords: 2DE; two-dimensional gel electrophoresis; APAF1; apoptotic protease-activating factor 1; CDWE; cell wall-degrading enzymes; CED4; cell death protein 4; ChIP seq; chromatin immunoprecipitation-sequencing; CoIP; co-immunoprecipitation; DIGE; fluorescence di
Vitamin E deficiency depressed gill immune response and physical barrier referring to NF-kB, TOR, Nrf2 and MLCK signalling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare
Keywords: LA; lysozyme; ACP; acid phosphatase; LEAP; liver-expressed antimicrobial peptide; IL; interleukin; TGF; transforming growth factor; NF-κB; nuclear factor kappa B; IκBα; inhibitory protein κBα; TOR; target of rapamycin; S6K1; ribosome protein S6 kinas
PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p
Keywords: COX-2; cyclooxygenase-2; PGE2; prostaglandin E2; ALT; alanine transaminase; TGF-β1; transforming growth factor β1; BAX; Bcl-2-associated X protein; Bcl-xL; B-cell lymphoma-extra-large; α-SMA; alpha smooth muscle actin; COL1A1; collagen type I alpha 1;
Transcriptome analysis reveals novel insights into the response of low-dose benzo(a)pyrene exposure in male tilapia
Keywords: TGFi; TGF induced factor homeobox; TGF; transforming growth factor; IL1; interleukin 1; IL1i; IL1 inhibitors; IL1RL1; interleukin 1 receptor like 1; TNF; tumor necrosis factor; Nogo; reticulon 4 (RTN4/Nogo); NGF; nerve growth factor; STC; stanniocalcin 1;
Original ArticleSTC2 as a novel mediator for Mus81-dependent proliferation and survival in hepatocellular carcinoma
Keywords: Mus81; Hepatocellular carcinoma; STC2; Proliferation; Apoptosis; Mus81; methyl methansulfonate and UV sensitive gene clone 81; HCC; hepatocellular carcinoma; STC2; Stanniocalcin 2; APC; adenomatous polyposis coli; APAF1; apoptotic protease activating fact
6-shogaol induces autophagic cell death then triggered apoptosis in colorectal adenocarcinoma HT-29 cells
Keywords: CRC; Colorectal cancer; PAHs; polycyclic aromatic hydrocarbons; PCD; program cell death; ER; endoplasmic reticulum; MOMP; mitochondrial outer membrane permeabilization; APAF1; apoptotic protease activating factor 1; DMSO; dimethyl sulfoxide; PI; propidium
Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway
Keywords: SETDB1; set domain, bifurcated 1; H3K9; histone H3 lysine 9; SSCs; spermatogonial stem cells; GDNF; glial cell line-derived neurotrophic factor; SFK; Src family kinase; PI3K; phosphatidylinositol 3-kinase; ESCs; embryo stem cells; DMEM/F12; Modified Eagle
Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle
Keywords: nonsense mutation; APAF1; dairy cattle; resequencing;
MicroRNA-877-5p is involved in the trovafloxacin-induced liver injury
Keywords: ABCF1; ATP binding cassette subfamily F member 1; ALT; alanine aminotransferase; APAF1; apoptotic protease activating factor 1; CCl4; carbon tetrachloride; CHOP; CCAAT enhancer-binding protein homologous protein; CYP3A4; cytochrome P450 family 3 subfamily
DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress
Keywords: Apaf1; apoptotic protease activating factor-1; Bcl-2; B cell lymphoma 2; DKO; Bax Bak double knockout; Drp1; Dynamin Related Protein 1; ER; endoplasmic reticulum; IMM; inner mitochondrial membrane; MEFs; mouse embryonic fibroblasts; MFN; mitofusin; MOMP;
PUMA is invovled in ischemia/reperfusion-induced apoptosis of mouse cerebral astrocytes
Keywords: Apaf1; apoptotic protease activating factor 1; DCFH; 2,7-dichlorofiuorescein; DCFH-DA; 2,7-dichlorofiuorescein diacetate; 4-HNE; 4-hydroxy-trans-2-nonenal; I/R; ischemia and reperfusion; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; N
The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes
Keywords: ALS; Amyotrophic Lateral Sclerosis; APAF1; Apoptotic protease activating factor 1; BH3-only protein; Bcl-2 homology domain 3-only protein; bid; BH3 interacting domain death agonist; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium-binding ada
Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death
Keywords: AkoMEFS; Apaf1 knock-out mice; Apaf1; apoptotic protease-activating factor 1; Cyt c; cytochrome c; DMEM; Dulbecco's Modified Eagle Medium; DOXO; doxorubicin; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; EGFP; enhanced green fluorescent pr
Crosstalk between apoptosis, necrosis and autophagy
Keywords: AIF; Apoptosis Inducing Factor; AMPK; Adenosine Monophosphate activated Kinase; APAF1; Apoptotic Protease Activating Factor 1; BCL-2; B-cell lymphoma 2; BCL-Xl; B-cell lymphoma extra large; BEC1; Beclin-1; BH; Bcl-2 homology; cIAP1; cellular inhibitor of
Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration
Keywords: MDA; malondialdehyde; 4-HNE; 4-hydroxynonenal; EAE; experimental allergic encephalomyelitis; MS; mutiple sclerosis; SSB; single strand break; DSB; double strand break; 8-OxoG; 8-hydroxyguanosine; 8-NO(2)-G; 8-nitroguanine; AP; apurinic/apyrmidinic; OGG1;
MicroRNAs in cancer management and their modulation by dietary agents
Keywords: ACTR1A; ARP1 actin-related protein 1 homolog A centractin alpha; AGTR1; angiotensin II receptor type 1; AICDA; activation-induced cytidine deaminase; AKT; v-akt murine thymoma viral oncogene homolog; ALL; acute lymphocytic leukemia; AML; acute myeloid leu
Histone modifications as a pathogenic mechanism of colorectal tumorigenesis
Keywords: AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem
Integrity of ATP binding site is essential for effective inhibition of the intrinsic apoptosis pathway by NAIP
Keywords: NOD, Nucleotide Binding Oligomerization Domain; BIR, Baculoviral IAP Repeat; NAIP, Neuronal Apoptosis Inhibitory Protein; SMAC, Second Mitochondrial derived Activator of Caspases; XIAP, X-linked Inhibitor of Apoptosis ProteinNAIP; APAF1; Nucleotide Bindin