Keywords: ATP7A; copper-histidine; de novo point mutation; Menkes disease;
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Keywords: Dog; Liver; Bedlington terrier; Labrador retriever; Wilson disease; ATP7A; ATP7B; COMMD1;
Keywords: Nrf2; NF-E2-related factor 2; Cu/Zn-SOD; copper/zinc-superoxide dismutase; CAT; catalase; HSF1; heat shock factor 1; HSF2; heat shock factor 2; HSP70; heat shock protein 70; NF-κB; nuclear transcription factor κB; IL-6; interleukin-6; IL-1β; interleuki
Keywords: Oxaliplatin; Drug transport; Cu transporters; Cu chelators; Colorectal cancer; Cytotoxicity; hCTR1; human copper transporter 1; ATP7A; P-type Cu++-transporting ATPase 7A; ATP7B; P-type Cu++-transporting ATPase 7B; ATTM; ammonium tetrathiomolybdate; BCS; b
Keywords: ADG; average daily gain; Atox1; antioxidant 1 copper chaperon; ATP7A; copper-transorting P-type ATPase; BW; body weight; CZn; changed dietary Zn group; CCS; copper chaperone for superoxide dismutase; CP; ceruloplasmin; Ctr1; copper transporter 1; DM; dry
Keywords: ZAC; zinc-activated channel; LGIC; ligand-gated ion channel; nACh; nicotinic acetylcholine; 5-HT; 5-hydroxytryptamine; GFP; green fluorescent protein; MOPS; 10 3-(N-morpholino)propanesulfonic acid; CTR1; high affinity copper uptake protein 1; GLIC; Gloeob
Keywords: Copper; Metal; Menkes; ATP7A; Neurodegeneration;
Keywords: Copper; Synapse; Neurotransmission; Neurodegeneration; ATP7A; NMDA;
Keywords: Menkes disease; ATP7A; Copper; Neurodevelopment; Brain growth
Keywords: ATP7A; DMT1; Polymorphism; Wilson's disease
Differential effects of β-glucan on oxidative stress, inflammation and copper transport in two intestinal regions of large yellow croaker Larimichthys crocea under acute copper stress
Keywords: ATP7A; Cu-transporting ATPase A; ATP7B; Cu-transporting ATPase B; CAT; catalase; CTR1; copper transporter 1; IL-1β; interleukin-1β; IL-6; interleukin-6; iNOS; nitric oxide synthase; MTs; Metallothioneins; MTF-1; metal-responsive element-binding transcri
Identification of eight copper (Cu) uptake related genes from yellow catfish Pelteobagrus fulvidraco, and their tissue expression and transcriptional responses to dietborne Cu exposure
Keywords: Cu; copper; CTR; copper transporter; ATOX1; antioxidant 1 copper chaperone; CCS; copper chaperone for superoxide dismutase; COX17; cytochrome c oxidase copper chaperone; ATP7A; ATPase copper transporting alpha; ATP7B; ATPase copper transporting beta; DMT1
Ceruloplasmin gene expression profile changes in the rat mammary gland during pregnancy, lactation and involution
Keywords: Cp; ceruloplasmin; GPI; glycosylphosphatidylinositol anchor; GPI-Cp; GPI anchored Cp; ATP7A; Menkes Cu-transporting ATPases; ATP7B; Wilson Cu-transporting ATPases; MG; mammary gland; P; pregnancy; L; lactation; Inv; involution; Growth-regression cycle of
Copper therapy reduces intravascular hemolysis and derepresses ferroportin in mice with mosaic mutation (Atp7amo-ms): An implication for copper-mediated regulation of the Slc40a1 gene expression
Keywords: ATP7A; Copper supplementation; Ferroportin, iron metabolism; Menkes disease; Mottled mice;
Neural effects in copper deficient Menkes disease: ATP7A-a distinctive marker
Keywords: Menkes disease; Copper; ATP7A; Neural mechanism; Cuproenzymes
Mitochondrial ClpP activity is required for cisplatin resistance in human cells.
Keywords: HClpP; HClpXP; Mitochondria; ATP7A; Copper transport; Apoptosis
Mechanistic basis of a combination d-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo
Keywords: ATP7A; copper-transporting ATPase 1; ATP7B; copper-transporting ATPase 2; ChIP; chromatin immunoprecipitation analysis; CI; combination index; hCtr1; human copper influx transporter 1; IHC; immunohistochemistry analysis; RT-qPCR; quantitative reverse tran
A Novel Two-Nucleotide Deletion in the ATP7A Gene Associated With Delayed Infantile Onset of Menkes Disease
Keywords: Menkes disease; ATP7A; translation reinitiation; premature termination codon;
Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone
Keywords: 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d
Effects of different sources of copper on Ctr1, ATP7A, ATP7B, MT and DMT1 protein and gene expression in Caco-2 cells
Keywords: ATP7A; ATP7B; Caco-2 cells; Ctr1; Nano copper oxide;
Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy
Keywords: Human copper transporter 1; Cisplatin; ATP7A; ATP7B; Non-small cell lung cancer; Prognosis
In utero copper treatment for Menkes disease associated with a severe ATP7A mutation
Keywords: Copper; ATP7A; Fetal therapy; Menkes disease; mRNA splicing;
The CXXC motifs in the metal binding domains are required for ATP7B to mediate resistance to cisplatin
Keywords: ATP7A; ATP7B; Metal binding sequences; Cisplatin; Platinum containing drugs
Involvement of the molecular chaperone Hspa5 in copper homeostasis in astrocytes
Keywords: Copper; Hspa5; Grp78; Atp7a; Astrocyte; Metallothionein
Zebrafish sod1 and sp1 expression are modulated by the copper ATPase gene atp7a in response to intracellular copper status
Keywords: Zebrafish; Copper; atp7a; sod1; sp1
Alterations in the expression of the Atp7a gene in the early postnatal development of the mosaic mutant mice (Atp7amo-ms) - An animal model for Menkes disease
Keywords: Copper metabolism; Cu-transporting ATPase; ATP7A; Metalloproteins; Mottled mice; Menkes disease;
Copper induces Cu-ATPase ATP7A mRNA in a fish cell line, SAF1
Keywords: Copper; Metals; ATP7A; MT; Microarray; qRT-PCR; Fish; Sparus aurata;
Pathology, clinical features and treatments of congenital copper metabolic disorders – Focus on neurologic aspects
Keywords: Copper; Menkes disease; Wilson’s disease; Occipital horn syndrome; ATP7A; ATP7B; Neurologic diseases
Menkes disease and infantile epilepsy
Keywords: Menkes; ATP7A; Epilepsy; Epileptogenesis; Lactic acidosis; Copper supplementation; Cupric chloride
Mammalian copper-transporting P-type ATPases, ATP7A and ATP7B: Emerging roles
Keywords: Copper; Copper homeostasis; ATP7A; ATP7B
ATP7B detoxifies silver in ciliated airway epithelial cells
Keywords: SCC1; silver carbene complex 1 (methylated caffeine silver acetate); mTEC; mouse tracheal epithelial cells; DAPI; 4â²,6-diamidino-2-phenylindole; β-tub; β-tubulin-IV; Silver; Copper; Antibacterial; Ciliated cells; ATP7A; ATP7B; CTR1; Airway; Mouse;
Multiple Cu-ATPase genes are differentially expressed and transcriptionally regulated by Cu exposure in sea bream, Sparus aurata
Keywords: Copper; Fish; Homeostasis; Cu-ATPases; ATP7A; ATP7B; ATOX1
Du gène à la maladie : les anomalies des transporteurs du cuivre
Keywords: ATP7A; ATP7B; Maladie de Wilson; Maladie de Menkès; Bases moléculairesATP7A; ATP7B; Wilson disease; Menkes disease; Molecular pathogenesis
Copper transport during lactation in transgenic mice expressing the human ATP7A protein
Keywords: ATP7A; ATP7B; Copper; Lactation; Mammary gland
Cellular multitasking: The dual role of human Cu-ATPases in cofactor delivery and intracellular copper balance
Keywords: ATP7A; ATP7B; P-type ATPase; Copper; Transport; Trafficking
The first reported case of Menkes disease caused by an Alu insertion mutation
Keywords: Copper metabolism; Menkes disease; ATP7A; Alu elements; Exonic splicing enhancer
Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells
Keywords: Cisplatin; Accumulation; Uptake; Efflux; Resistance; Transport; ACTB; β-actin; ATP7A; ATPase, copper transporting, alpha polypeptide; ATP7B; ATPase, copper transporting, beta polypeptide; B2M; beta-2-microglobulin; hCTR1; human copper transporter 1; DEPC
ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis
Keywords: ATP7A; Menkes disease; Olfactory system; Olfactory sensory neurons; Neurodevelopment; Axonal outgrowth; Synapse
Biochemical basis of regulation of human copper-transporting ATPases
Keywords: ATP7A; ATP7B; Copper; P-Type ATPase; Atox1;
Trafficking of the copper-ATPases, ATP7A and ATP7B: Role in copper homeostasis
Keywords: Copper homeostasis; P-type ATPase; ATP7A; ATP7B; Menkes disease; Wilson disease; Trafficking
Role of copper transporters in the uptake and efflux of platinum containing drugs
Keywords: Platinum containing drugs; Copper; Drug resistance; ATP7A; ATP7B; CTR1DDP, cisplatin; CBDCA, carboplatin; LOHP, oxaliplatin; ICP-MS, inductivity coupled plasma mass spectrometry; CTR1, copper transporter 1
Phenotypic and genetic characterization of the Atp7aMo-Tohm mottled mouse: A new murine model of Menkes disease
Keywords: Menkes disease; Mottled mouse; Atp7a; Copper deficiency; Yolk sac; Embryonic lethality; Transgene
Copper-dependent interaction of glutaredoxin with the N termini of the copper-ATPases (ATP7A and ATP7B) defective in Menkes and Wilson diseases
Keywords: Metal-binding domain; Protein–protein interaction; Copper; Glutaredoxin; GRX1; Menkes disease; Wilson disease; P-type ATPase; ATP7A; ATP7B
Copper transporters regulate the cellular pharmacology and sensitivity to Pt drugs
Keywords: ATP7A; ATP7B; Carboplatin; Cisplatin; Copper; hCTR1; Oxaliplatin;