Keywords: BCR، گیرنده سلولی B; PCR, polymerase chain reaction; MID, multiplex identifier; TCR, T cell receptor; BCR, B cell receptor; CLL, chronic lymphatic leukemia; IMGT, international ImMunoGeneTics information system; GI, germline identity; DNA, desoxyribonucleic acid; GS, genome s
مقالات ISI BCR، گیرنده سلولی B (ترجمه نشده)
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Keywords: BCR، گیرنده سلولی B; AHR, aryl hydrocarbon receptor; TCDD, 2,3,7,8-Tetrachlorodibenzo-p-dioxin; DRE, dioxin response element; CD40L, CD40 ligand; BCR, B cell receptor; SHP-1, Src homology phosphatase-1; PTPN6, protein tyrosine phosphatase, non-receptor type 6; BCL-6, B cell l
Evolutionary implication of B-1 lineage cells from innate to adaptive immunity
Keywords: BCR، گیرنده سلولی B; VLR, variable lymphocyte receptor; BCR, B cell receptor; TCR, T cell receptor; mIgM, membrane IgM; APCs, antigen-presenting cells; CMPs, common myelo-erythroid progenitors; CLPs, common lymphoid progenitorsB-1 cells; B-2 cells; Macrophages; Evolution of B
Toll like receptor mediated immune stimulation can be visualized in vivo by [18F]FDG-PET
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; CpG, cytosine-phosphate-guanine; CT, computer tomography; [18F]FDG, [18F]-2-fluorodeoxyglucose; LN, lymph node; LPS, lipopolysaccharide; MRI, magnetic resonance imaging; PET, positron emission tomography; TLR, toll-like receptor[18F]
Progress in the use of swine in developmental immunology of B and T lymphocytes
Keywords: BCR، گیرنده سلولی B; Porcine immune system; Lymphocytes; Ontogeny; Development; DifferentiationAID, activation-induced cytidine deaminase; BCR, B cell receptor; CDR3, complementary determining region 3; CpG, methylated sequences of DNA; CSR, class switch recombination; GF, ge
Update on the role of autophagy in systemic lupus erythematosus: A novel therapeutic target
Keywords: BCR، گیرنده سلولی B; SLE, systemic lupus erythematosus; fDCs, follicular dendritic cell; BCR, B cell receptor; NET, neutrophil extracellular trap; mTOR, mammalian target of rapamycin; MHP, mitochondrial hyperpolarization; mTORC1, mTOR complexSystemic lupus erythematosus; Auto
Interferon-α induces altered transitional B cell signaling and function in Systemic Lupus Erythematosus
Keywords: BCR، گیرنده سلولی B; Lupus; B cell; SYK; Hyper-responsive; Interferon-alphaAbs, antibodies; SLE, Systemic Lupus Erythematosus; BCR, B cell receptor; IFN, interferon; p-, phospho-
Deletion of WASp and N-WASp in B cells cripples the germinal center response and results in production of IgM autoantibodies
Keywords: BCR، گیرنده سلولی B; B cells; Germinal center; Autoimmunity; Primary immunodeficiency; Wiskott-Aldrich syndrome; N-WASpAID, activation induced deaminase; BCR, B cell receptor; CH, constant heavy chain; DZ, dark zone; FDCs, follicular dendritic cells; GC, germinal center; GEF,
Characterization of SM201, an anti-hFcγRIIB antibody not interfering with ligand binding that mediates immune complex dependent inhibition of B cells
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; chSM201, chimeric SM201; FcγRIIB, inhibitory IgG receptor; ICs, immune complexes; ITAM, immunoreceptor tyrosine-based activating motif; ITIM, immunoreceptor tyrosine-based inhibitory motif; h, human; rSM201, rat SM201Autoimmune disea
CD9 may contribute to the survival of human germinal center B cells by facilitating the interaction with follicular dendritic cells
Keywords: BCR، گیرنده سلولی B; Ag, antigen; BCR, B cell receptor; GC, germinal center; FDC, follicular dendritic cells; PC, plasma cellsCD9; Germinal center B cells; Follicular dendritic cells; VLA4; VCAM-1; Apoptosis
The selection of mature B cells is critically dependent on the expression level of the co-receptor CD19
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; FoB, follicular B cell; HSC, Hematopoietic stem cell; Ig, Immunoglobulin; MZB, marginal zone B cell; OV.EX. CD19, over-expression of murine CD19; shCD19 shRNA, directed against murine CD19 mRNACD19; Nup98–HoxB4; B cell development; S
B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice
Keywords: BCR، گیرنده سلولی B; ABC, accelerated blood clearance; BCR, B cell receptor; CHOL, cholesterol; DC, dendritic cells; DC-6-14, O,O′-ditetradecanoyl-N-(α-trimethyl ammonio acetyl) diethanolamine chloride; DOPE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; ELISA, enzyme-linked
Suppression of allergen-specific B lymphocytes by chimeric protein-engineered antibodies
Keywords: BCR، گیرنده سلولی B; Dpt, Dermatophagoides pteronyssinus; CR1, complement receptor 1; PBMCs, peripheral blood mononuclear cells; HDM, house dust mite; dsDNA, double stranded DNA; scFv, single chain Fv; SLE, systemic lupus erythematosus; BCR, B cell receptor; FITC, fluorescein
Generation of a novel Cr2 gene allele by homologous recombination that abrogates production of Cr2 but is sufficient for expression of Cr1
Keywords: BCR، گیرنده سلولی B; Cr1/CR1, complement receptor 1; Cr2/CR2, complement receptor 2; C3, complement component 3; BCR, B cell receptor; s, follicular dendritic cell; SCR, short consensus repeat; PCR, polymerase chain reaction; TK, thymidine kinase; WT, wild type; SS, signal se
Roles of ligands from the TNF superfamily in B cell development, function, and regulation
Keywords: BCR، گیرنده سلولی B; Ab, antibody; AICD, activation-induced cell death; AD, autoimmune disease; Ag, antigen; APRIL, a proliferation inducing ligand; BAFF, B cell activating factor of the TNF family; BAFFR, BAFF receptor; BCMA, B cell maturation antigen; BCR, B cell receptor;
Phospholipase C-β in immune cells
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; CT, C-terminal; DAG, diacylglycerol; dko, double knockout; GAP, GTPase-activating protein; GPCR, G-protein-coupled receptor; HSC, hematopoietic stem cell; IL, interleukin; IP3, inositol 1,4,5-trisphosphate; ITAM, immunoreceptor tyros
The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses
Keywords: BCR، گیرنده سلولی B; aTregs, activated regulatory T cells; BCR, B cell receptor; cpf T cells, cytokine-producing FoxP3+ T cells; CSK, C-terminal SRC kinase; LYP, lymphoid tyrosine phosphatase; PKA, protein kinase A; PTP, protein tyrosine phosphatase; rTregs, resting regulator
A myriad of functions and complex regulation of the CCR7/CCL19/CCL21 chemokine axis in the adaptive immune system
Keywords: BCR، گیرنده سلولی B; APC, antigen-presenting cell; BCR, B cell receptor; CCL, CC chemokine ligand; CCR, CC chemokine receptor; TCM, central memory T cell; CNS, central nervous system; CMJ, cortico-medullary junction; CXCL, CXC chemokine ligand; CXCR, CXC chemokine receptor; D
Cell-specific in vivo functions of glycosphingolipids: Lessons from genetic deletions of enzymes involved in glycosphingolipid synthesis
Keywords: BCR، گیرنده سلولی B; APP, amyloid precursor protein; AlbCre, albumin-cre; BCR, B cell receptor; CD19, cluster of differentiation 19; C. elegans, Caenorhabditis elegans; CoA, coenzyme A; CNP, 2′,3′-cyclic nucleotide 3′ phosphodiesterase; Cst, cerebroside sulfotransferase; EGF,
Gene expression signature in transplantation tolerance
Keywords: BCR، گیرنده سلولی B; ADORA, Adenosine A3 Receptor; BANK, B Cell Scaffold Protein with Ankyrin Repeats; BCR, B Cell Receptor; Bregs, B Regulatory Cells; FOXP3, Forkhead Box P3; IFN, Inteferon Gamma; KTFS, Kidney Transplant Failure Score; NK-Cells, Natural Killer Cells; PAM, Pr
Promoter CpG methylation status in porcine Lyn is associated with its expression levels
Keywords: BCR، گیرنده سلولی B; BSP, Bisulfite sequencing PCR; BCR, B cell receptor; cDNA, Complementary DNA; CpG, Cytosine-guanine dinucleotide; dNTP, Deoxy-ribonucleoside triphosphate; LYN, v-yes-1 Yanaguchi sarcoma viral related oncogene homolog; PCR, Polymerase chain reaction; PTGS,
The B cell receptor-induced calcium flux involves a calcium mediated positive feedback loop
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; Ca2+, calcium; [Ca2+]i, intracellular calcium concentration; CC, coiled-coil; CRAC, calcium-release activated calcium channels; EF, EF-hand; ER, endoplasmic reticulum; IP3, inositol-1,4,5-trisphosphate; IP3R, IP3 receptors; LC, low c
Resolve, revise, and relax: The 3 Rs of B cell repertoire adjustment
Keywords: BCR، گیرنده سلولی B; Ab, antibody; BCMA, B cell maturation antigen; BCDT, B cell depletion therapy; BCR, B cell receptor; BLyS, B lymphocyte stimulator; BM, bone marrow; bNAb, broadly neutralizing antibody; BR3, BLyS receptor 3; FO, follicular; GC, germinal center; HIV, human
The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity
Keywords: BCR، گیرنده سلولی B; AMD, age related macular degeneration; AIRE, autoimmune regulator gene; BCR, B cell receptor; CMCC, chronic mucocutaneous candidiasis; HSV-1, herpes simplex virus type 1; IRAK4, interleukin-1 receptor-associated kinase 4; IMEM, isocoves minimum essential
Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells
Keywords: BCR، گیرنده سلولی B; APC, antigen presenting cell; BCR, B cell receptor; FAK, focal adhesion kinase; ICAM-1, intercellular adhesion molecule-1; LFA-1, lymphocyte function-associated antigen-1 (αLβ2 integrin); MZ, marginal zone; PI3K, phosphoinositide 3-kinase; P-Akt, phospho-
B cell maintenance and function in aging
Keywords: BCR، گیرنده سلولی B; Ab, antibody; ABC, age-associated B cell; ASC, antibody-secreting cell; BCR, B cell receptor; BLyS, B lymphocyte stimulato or BAFF; BM, bone marrow; GC, germinal center; HSC, hematopoietic stem cell; Ig, immunoglobulin IMM; B, immature B cells; LLPC, long
Experimental models of B cell tolerance in transplantation
Keywords: BCR، گیرنده سلولی B; 3-83KI mice, 3-83-knockin mouse; ADCC, antibody-dependent cellular cytotoxicity; AHR, acute humoral rejection; APC, antigen presenting cells; B10 cells, IL-10-producing regulatory B cells; BCR, B cell receptor; DSA, donor specific antibody; EAE, experimen
Models and methods for analysis of lymphocyte repertoire generation, development, selection and evolution
Keywords: BCR، گیرنده سلولی B; ABM, agent-based models; BCR, B cell receptor; NK, natural killer; TCR, T cell receptor; SHM, somatic hypermutationB cell receptor; Computer simulations; High-throughput sequencing; Immunoglobulin; Lymphocyte repertoires; Mathematical models; Natural kill
Type I interferons directly down-regulate BCL-6 in primary and transformed germinal center B cells: Differential regulation in B cell lines derived from endemic or sporadic Burkitt’s lymphoma
Keywords: BCR، گیرنده سلولی B; AID, activation-induced cytidine deaminase; BCR, B cell receptor; BL, Burkitt’s lymphoma; CD40L, CD40 ligand; CHX, cycloheximide; eBL, endemic BL; EBV, Epstein–Barr virus; ERK, extracellular signal regulated kinase; GC, germinal center; IFN, interferon; I
Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens
Keywords: BCR، گیرنده سلولی B; 111In-DTPA, 111In-labeled diethylenetriaminepentaacetic acid; APC, antigen presenting cell; ATRA, all-trans retinoic acid; BCR, B cell receptor; BSA, bovine serum albumin; CCS, ceramide carbamoyl-spermine; Chol, cholesterol; CLR, C-type lectin receptor; C
Regulation of BCR signaling
Keywords: BCR، گیرنده سلولی B; BCAP, B cell adaptor molecule for PI3K; BCR, B cell receptor; BLNK, B-cell linker; IKK, IκB kinase; IP3, inositol-1,4,5-trisphosphate; ITAM, immunoreceptor tyrosine-based activation motif; PI3K, phosphoinositide 3-kinase; PIP2, phosphatidylinositol-4,5-bi
Activated T cells induce rapid CD83 expression on B cells by engagement of CD40
Keywords: BCR، گیرنده سلولی B; Ag, antigen; APC, antigen presenting cell; BCR, B cell receptor; CD, cluster of differentiation; CD40L, CD40 ligand; DC, dendritic cell; FITC, fluorescein isothiocyanate; Ig, immunoglobulin; L. major, Leishmania major; LPS, lipopolysaccharide; mAb, monocl
Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; O2−, superoxide; PKC, protein kinase C; PMA, phorbol 12-myristate 13-acetateHelios; Apoptosis; Superoxide; Protein kinase C; DT40; Gene targeting
Inositol 1,4,5-trisphosphate 3-kinase B controls survival and prevents anergy in B cells
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; Fo, follicular; Itpkb, inositol 1,4,5-trisphosphate 3-kinase type B; MZ, marginal zone; T1, transitional 1; T2, transitional 2Anergy; B cell survival; Bim; Itpkb; Lymphocyte selection
T cell hybridomas to study MHC-II restricted B-cell receptor-mediated antigen presentation by human B cells
Keywords: BCR، گیرنده سلولی B; APC, antigen presenting cell; BCR, B cell receptor; TCR, T-cell receptor; RT, reverse transcriptase; HAT, hypoxanthine/aminopterin/thymadineB cells; Antigen presentation; B cell receptor; MHC class II
Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim-1)
Keywords: BCR، گیرنده سلولی B; Tim-1, T cell and immunoglobulin domain 1 (other names include Timd-1 and Havcr-1); BCR, B cell receptor; TCR, T cell receptor; SH2, Src homology 2 domainTim-1; Havcr-1; B cell; Fyn; Signaling
Physiology and pathology of proteostasis in the early secretory compartment
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; ER, endoplasmic reticulum; ERAD, ER associated degradation; ERGIC, ER-Golgi intermediate compartment; ESC, early secretory compartment; QC, quality control; RB, Russell bodies; UPR, unfolded protein responseB cell differentiation; ER
Epigenetic and 3-dimensional regulation of V(D)J rearrangement of immunoglobulin genes
Keywords: BCR، گیرنده سلولی B; AcH3, acetylated-histone H3; BCR, B cell receptor; CTCF, CCCTC-binding factor; ChIP, chromatin immunoprecipitation; E, enhancer; H3K4me2, histone H3 dimethylated at lysine 4; H3K4me3, histone H3 trimethylated at lysine 4; H3K27me3, histone H3 trimethylate
An evolutionary conserved motif is responsible for Immunoglobulin heavy chain packing in the B cell membrane
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; CART, conserved antigen receptor transmembrane; CCP4, collaborative computational project number 4; DSSP, dictionary of protein secondary structure; EMPD, extra-cellular membrane proximal domain; FEL, fixed effects likelihood; Ig, im
Interaction of calmodulin with Bcl10 modulates NF-κB activation
Keywords: BCR، گیرنده سلولی B; CaM, calmodulin; TCR, T cell receptor; BCR, B cell receptor; CBM, Carma1, Bcl10, Malt1 complex; IKK, IκB kinase; PKC, protein kinase C; CARD, caspase recruitment domain; IP3, inositol-1,4,5-triphosphate; CRAC, calcium release-activated Ca2+ channel; CaMK,
The pre-B cell receptor checkpoint
Keywords: BCR، گیرنده سلولی B; aa, amino acids; BCR, B cell receptor; CD, cluster of differentiation; CDR, complementarity determining region; D, diversity; H chain, heavy chain; Ig, immunoglobulin; J, joining; L chain, light chain; λ5 T, λ5-deficient mice; λ5-UR, λ5 unique region; μMT
Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinase
Keywords: BCR، گیرنده سلولی B; AMC, amino-methyl coumarin; BCR, B cell receptor; β-gal, beta-galactosidase; Cbl, Casitas B-lineage lymphoma; CETAB, cetyltrimethyl ammonium bromide; DUB, deubiquitinating enzyme; ECL, enhanced chemiluminescence; FL, full length; IB, immunoblot; IP, immun
Somatic hypermutation and antigen-driven selection of B cells are altered in autoimmune diseases
Keywords: BCR، گیرنده سلولی B; Germinal center; Somatic hypermutation; Immunoglobulin (Ig); Autoimmune diseases; Rheumatoid Arthritis (RA); Multiple Sclerosis (MS); Sjögren’s Syndrome (SS)AA, amino acid; AI, autoimmune; AID, Activation-induced cytidine deaminase; BCR, B cell receptor;
Inhibiting NF-κB activation by small molecules as a therapeutic strategy
Keywords: BCR، گیرنده سلولی B; AgR, antigen receptor; ATM, ataxia-telangiectasia mutant; BAFF, B-cell activating factor; BCL, B-cell lymphoma; BCR, B cell receptor; CARMA, CARD-containing MAGUK protein; CD40L, CD40 ligand; CK, casein kinase; DSBS, Doublestranded DNA breaks; ECSIT, evol
Toll-like receptors in systemic lupus erythematosus; prospects for therapeutic intervention
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; FcγR, Fcγ receptors; pDC, plasmacytoid dendritic cells; ROS, reactive oxygen species; snRNPs, small nuclear ribonucleoprotein particles; TLR, toll-like receptorInnate immunity; Tolerance defect; TLR-7; TLR-9; Lupus
B cell receptor crosstalk: B cells express osteopontin through the combined action of the alternate and classical BCR signaling pathways
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; Opn, osteopontin; FO, follicular; MZ, marginal zone; ELISA, enzyme-linked immunosorbent assay; IL-4, interleukin-4; ETA-1, early T lymphocyte activator 1; SPP1, secreted phosphoprotein 1; EAE, experimental autoimmune encephalomyeliti
A model for the development of human IgD-only B cells: Genotypic analyses suggest their generation in superantigen driven immune responses
Keywords: BCR، گیرنده سلولی B; PB, peripheral blood; BCR, B cell receptor; FR, framework region; CDR, complementarity determining region; GC, germinal center; R/S, replacement versus silent mutations; MID, Moraxella IgD binding proteinClonality; IgD; Memory B cells; Somatic hypermutati
H2O2 inhibits BCR-dependent immediate early induction of EBV genes in Burkitt's lymphoma cells
Keywords: BCR، گیرنده سلولی B; BCR, B cell receptor; BL, Burkitt's lymphoma; Cat, catalase; coelenterazine, 2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-benzyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one; CL, chemiluminescence; EBV, Epstein–Barr virus; GO, glucose oxidase; HX, hypoxanthine; HB
Synovial B cells of rheumatoid arthritis express ZAP-70 which increases the survival and correlates with the inflammatory and autoimmune phenotype
Keywords: BCR، گیرنده سلولی B; RA, rheumatoid arthritis; RF, rheumatoid factor; CCP, cyclic-citrullinated peptide; BCR, B cell receptor; CLL, chronic lymphocytic leukaemia; ZAP-70, Zeta-associated protein of 70kDa; SF, synovial fluid; OA, osteoarthritisRheumatoid arthritis; B cells; ZA
Identification of DNA-reactive B cells in patients with systemic lupus erythematosus
Keywords: BCR، گیرنده سلولی B; SLE, systemic lupus erythematosus; Ig, immunoglobulin; BCR, B cell receptor; FR, framework region; CDR, complementarity-determining regionLupus; B cells; Immunoglobulins; Peptide