Keywords: بتا-دگرساز; Alzheimer's Disease; Beta-secretase; BACE1; Transmembrane helix; Transmembrane domain; Helix packing; Trimer; Copper; Metal ion; Sulfur; Methionine; Cysteine; Channels and transporters; Molecular dynamics; MD simulations;
مقالات ISI بتا-دگرساز (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: بتا-دگرساز; Polyphenols; Amyloid beta; Beta-secretase; Neurodegenerations; Grape; Cognitive functions
Review of the advances in treatment for Alzheimer disease: strategies for combating β-amyloid protein
Keywords: بتا-دگرساز; Alzheimer disease; Beta-amyloid; Beta-secretase; Gamma-secretase; Amyloid hypotheses; Alzheimer; Beta-amiloide; Beta-secretasa; Gamma-secretasa; Hipótesis amiloidea;
Una revisión de los avances en la terapéutica de la enfermedad de Alzheimer: estrategia frente a la proteÃna β-amiloide
Keywords: بتا-دگرساز; Alzheimer; Beta-amiloide; Beta-secretasa; Gamma-secretasa; Hipótesis amiloidea; Alzheimer disease; Beta-amyloid; Beta-secretase; Gamma-secretase; Amyloid hypotheses;
A colorimetric strategy for assay of protease activity based on gold nanoparticle growth controlled by ascorbic acid and Cu(II)-coordinated peptide
Keywords: بتا-دگرساز; Protease; ATCUN motif; Gold nanoparticles; Copper ion; Ascorbic acid; Beta-secretase;
Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheime
Keywords: بتا-دگرساز; Alzheimer's; Aβ; Phospho-tau; Beta-secretase; Atypical PKC; PKC-iota/lambda; PKM-zeta; Insulin; Metformin; Akt;
A review on flavonoid-based scaffolds as multi-target-directed ligands (MTDLs) for Alzheimer's disease
Keywords: بتا-دگرساز; Chromanone; Multi-target drug ligands (MTDLs); Cholinesterase; Beta-secretase; Monoamine oxidase; Amyloid-β;
GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells
Keywords: بتا-دگرساز; Aβ; amyloid beta peptide; AD; Alzheimer's disease; ADAM; A disintegrin and metalloproteinase; APOE; apolipoprotein E; APP; amyloid precursor protein; BACE1; beta-secretase; CHO; Chinese hamster ovary; CTF; C-terminal fragment; DN; dominant negative; FA
Design, synthesis, in silico and in vitro screening of 1,2,4-thiadiazole analogues as non-peptide inhibitors of beta-secretase
Keywords: بتا-دگرساز; Beta-secretase; 1,2,4-Thiadiazoles; Molecular docking; In vitro FRET assay
Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates
Keywords: بتا-دگرساز; Alzheimer's disease; Beta-secretase; BACE-1 inhibitor;
Expression and processing of fluorescent fusion proteins of amyloid precursor protein (APP)
Keywords: بتا-دگرساز; APP106; truncated last 106 amino acids of APP; GappR; GFP-APP106-DsRed; RappG; DsRed-APP106-GFP; sGapp; soluble GFP-APP; sRapp; soluble DsRed-APP; sGappα; soluble GFP-APP alpha; sGappβ; soluble GFP-APP beta; Amyloid precursor protein; Amyloid-beta; Gree
Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines
Keywords: بتا-دگرساز; Alzheimer's disease; Alpha-secretase; Beta-secretase; Amyloid precursor protein;
Elucidating the catalytic mechanism of β-secretase (BACE1): A quantum mechanics/molecular mechanics (QM/MM) approach
Keywords: بتا-دگرساز; Alzheimer's disease; Aspartyl proteases; Beta-secretase; Protein hydrolysis; Acid-base mechanism
BACE1 elevation is associated with aberrant limbic axonal sprouting in epileptic CD1 mice
Keywords: بتا-دگرساز; Aberrant neuroplasticity; Temporal lobe epilepsy; Mossy fiber sprouting; Dystrophic neurites; Beta-secretase; Alzheimer's disease;
Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE)
Keywords: بتا-دگرساز; Alzheimer’s; Beta-secretase; BACE; Transition-state isostere
Effect of dietary quercetin on brain quercetin levels and the expression of antioxidant and Alzheimer's disease relevant genes in mice
Keywords: بتا-دگرساز; Quercetin; Brain; Alzheimer disease; Beta-secretase; BACE1
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model
Keywords: بتا-دگرساز; Alzheimer's disease; Transgenic mice; Amyloid beta; Beta-secretase; Neprilysin; Gender difference; Oligomer; Tau; Hyperphosphorylation
Thiophene substituted acylguanidines as BACE1 inhibitors
Keywords: بتا-دگرساز; Beta-secretase; BACE1; Aspartyl protease; Acylguanidine
Cholinesterase inhibitors influence APP metabolism in Alzheimer disease patients
Keywords: بتا-دگرساز; Alzheimer's disease; Platelets; APP metabolism; Cholinesterase inhibitors; Alpha-secretase; Beta-secretase; ADAM10;