Keywords: ارزیابی بیولوژیکی; Carbamates; Butyrylcholinesterase; Inhibitor; Synthesis; Biological evaluation; Physicochemical properties; Docking studies;
مقالات ISI ارزیابی بیولوژیکی (ترجمه نشده)
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Keywords: ارزیابی بیولوژیکی; Respiratory syndrome; Coronavirus; 3CL protease; 1,2,3-triazole; Biological evaluation;
Keywords: ارزیابی بیولوژیکی; ISO 10993 standard; Collagen; Local tissue reaction; In vivo degradation; Biological evaluation;
Keywords: ارزیابی بیولوژیکی; Carb; Carbopol 934P®; Hyp; hypericin; PAS; Photoacoustic Spectroscopy; PDI; photodynamic inactivation; PDT; photodynamic therapy; Polox; poloxamer 407; ROS; reactive oxygen species; TPA; Texture Profile Analysis; Biodegradable polymers; Hypericin; Photod
Keywords: ارزیابی بیولوژیکی; Boswellic acid analogues; AKBA; Biological evaluation; Human tumor cell lines; Cytotoxic activity;
Keywords: ارزیابی بیولوژیکی; Erectile dysfunction; Labelling; Vardenafil; Technetium-99m; Tracer; Biological evaluation;
Keywords: ارزیابی بیولوژیکی; Synthesis; Biological evaluation; 2-Arylimino-3-pyridin-thiazolineone derivatives; Antibacterial agents;
Keywords: ارزیابی بیولوژیکی; GABA uptake; mGAT1; Nipecotic acid; Suzuki–Miyaura reaction; Biological evaluation
Keywords: ارزیابی بیولوژیکی; Microwave promoted reactions; Quinoline-pyrazoline analogs; Biological evaluation; Cytotoxicity;
Keywords: ارزیابی بیولوژیکی; Non-azole; Biological evaluation; Structure–activity relationships; Synthesis; Antifungal agents
Keywords: ارزیابی بیولوژیکی; Polymeric micelles; Biomimetic; Phosphorylcholine; Drug release; Biological evaluation
Keywords: ارزیابی بیولوژیکی; Isoniazid; Thioamides; Synthesis; Biological evaluation; Antitubercular activity;
Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists
Keywords: ارزیابی بیولوژیکی; Type-2 diabetes mellitus; PPAR-γ; FFAR1; Thiazolidindione; Biological evaluation;
Eco-friendly synthesis, biological activity and evaluation of some new pyridopyrimidinone derivatives as corrosion inhibitors for API 5L X52 carbon steel in 5% sulfamic acid medium
Keywords: ارزیابی بیولوژیکی; Synthesis; Pyridopyrimidinone; API 5L X52 carbon steel; Corrosion; Biological evaluation; MD;
Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors
Keywords: ارزیابی بیولوژیکی; Antimicrobials; Biological evaluation; FtsZ; Structure-activity relationships; 5-Methylphenanthridium derivatives;
Biological evaluation and molecular docking of Rhein as a multi-targeted radiotherapy sensitization agent of nasopharyngeal carcinoma
Keywords: ارزیابی بیولوژیکی; Nasopharyngeal carcinoma; Rhein; Inverse docking; Multi-target radiotherapy sensitization agent; Biological evaluation;
Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors
Keywords: ارزیابی بیولوژیکی; Steroid synthesis; Nuclear receptor modulation; Molecular modelling; Biological evaluation;
Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations
Keywords: ارزیابی بیولوژیکی; Liver X receptors; Oxysterols; Steroid synthesis; Molecular modelling; Biological evaluation;
Synthesis and biological evaluation of chemical tools for the study of Dolichol Linked Oligosaccharide Diphosphatase (DLODP)
Keywords: ارزیابی بیولوژیکی; CDG; Diphosphatase; Phosphosugars; Disubstituted diphosphates; Biological evaluation; Glycochemistry;
New copper(II) complex with bioactive 2-acetylpyridine-4N-p-chlorophenylthiosemicarbazone ligand: Synthesis, X-ray structure, and evaluation of antioxidant and antibacterial activity
Keywords: ارزیابی بیولوژیکی; Thiosemicarbazones; Copper(II) complex; Biological evaluation; Antibacterial; Antioxidant; WOWWFNBDUZTYDD-LCCCTGDHSA-L; KRCPOZLWYUZVBS-VCHYOVAHSA-N;
Facile synthesis, biological evaluation and molecular docking studies of novel substituted azole derivatives
Keywords: ارزیابی بیولوژیکی; Triazole Schiff bases; Biological evaluation; Kinetic analysis; Molecular modeling; Single crystal XRD;
Design, synthesis and biological evaluation of 1H-pyrrolo[2,3-b]pyridine and 1H-pyrazolo[3,4-b]pyridine derivatives as c-Met inhibitors
Keywords: ارزیابی بیولوژیکی; c-Met inhibitor; Azaindole; Azaindazole; Synthesis; Biological evaluation
Novel biologically active series of N-acetylglucosamine derivatives for the suppressive activities on GAG release
Keywords: ارزیابی بیولوژیکی; Biological evaluation; Glucosamine; N-Acetylglucosamine derivatives; GAGs; glycosaminoglycans; PGs; proteoglycans; IL-1; interleukin 1;
Evaluation of the biocompatibility of a hydroxyapatite-CaTiO3 coating in vivo
Keywords: ارزیابی بیولوژیکی; Biological evaluation; Biomechanics testing; Coatings; HA-CaTiO3; Hydroxyapatite
Two novel 2D waves copper(II) coordination polymer with the quinolone antimicrobial drugs ciprofloxacin: Synthesis, structure and biological evaluation
Keywords: ارزیابی بیولوژیکی; Copper(II); Ciprofloxacin; Coordination polymer; Crystal structure; Biological evaluation
Synthesis, characterization and biological evaluation of ferrocene based poly(azomethene)esters
Keywords: ارزیابی بیولوژیکی; Synthesis; Characterization; Poly(azomethine)esters; Biological evaluation; MEO docking; Binding constants
Synthesis and biological activities of some new isonicotinic acid 2-(2-hydroxy-8-substituted-tricyclo[7.3.1.02.7]tridec-13-ylidene)-hydrazides
Keywords: ارزیابی بیولوژیکی; Isoniazid; Tricyclotridecanolones; Synthesis; Biological evaluation
Design, synthesis, and biological evaluation of amide imidazole derivatives as novel metabolic enzyme CYP26A1 inhibitors
Keywords: ارزیابی بیولوژیکی; All-trans-retinoic acid (ATRA); CYP26A1; Amide imidazole derivatives; Binding model; Biological evaluation
Syntheses, spectroscopic characterization, thermal study, molecular modeling, and biological evaluation of novel Schiff’s base benzil bis(5-amino-1,3,4-thiadiazole-2-thiol) with Ni(II), and Cu(II) metal complexes
Keywords: ارزیابی بیولوژیکی; Schiff’s bases; Metal complexes; Molecular modeling; Spectral studies; Biological evaluation
Synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-γ-butyrolactones as potent antitumor agents
Keywords: ارزیابی بیولوژیکی; Lactones; Paraconic acid analogs; Multicomponent reaction; Biological evaluation; Cytotoxic activity
Design, synthesis and preliminary biological evaluation of indoline-2,3-dione derivatives as novel HDAC inhibitors
Keywords: ارزیابی بیولوژیکی; Indoline-2,3-dione derivatives; HDAC inhibitors; Synthesis; Biological evaluation; QSAR;
Design and synthesis of piperidine derivatives as novel human heat shock protein 70 inhibitors for the treatment of drug-resistant tumors
Keywords: ارزیابی بیولوژیکی; HSP70 inhibitors; Lapatinib-resistant breast cancer cell; Biological evaluation;
Design, synthesis and biological evaluation of indole derivatives as novel inhibitors targeting B-Raf kinase
Keywords: ارزیابی بیولوژیکی; B-Raf kinase inhibitors; Receptor-based drug discovery; Indole derivatives; Biological evaluation
Synthesis and biological evaluation of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors
Keywords: ارزیابی بیولوژیکی; PARP-1 inhibitor; 4-(Thiophen-2-ylmethyl)-2H-phthalazin-1-ones; Synthesis; Biological evaluation; Antitumor;
Bioactive compounds from the insect Aspongopus chinensis
Keywords: ارزیابی بیولوژیکی; Aspongopus chinensis; Insects; Norepinephrine derivatives; Sesquiterpenoids; Lactam; Biological evaluation
Thymine vanadyl(II) compound as a diabetic drug model: Chemical spectroscopic and antimicrobial assessments
Keywords: ارزیابی بیولوژیکی; Vanadyl sulfate; Thymine; Spectroscopic studies; Biological evaluation
Synthesis, biological evaluation and SAR studies of novel bicyclic antitumor platinum(IV) complexes
Keywords: ارزیابی بیولوژیکی; Cisplatin; Platinum(IV) complexes; SAR study; Cancer; Biological evaluation; Malonatoplatinum complexes
Synthesis and microbiological evaluation of several benzocaine derivatives
Keywords: ارزیابی بیولوژیکی; Benzocaine; Synthesis; Structure; Biological evaluation
Radiosynthesis and biological evaluation of 5-(3-[18F]Fluoropropyloxy)-L-tryptophan for tumor PET imaging
Keywords: ارزیابی بیولوژیکی; 5-(3-[18F]fluoropropyloxy)-L-tryptophan([18F]-L-FPTP); Radiosynthesis; PET; Biological evaluation
First synthesis and biological evaluation of indeno[2,1-e]pyrazolo[3,4-b]pyrazin-5-one and related derivatives
Keywords: ارزیابی بیولوژیکی; Pyrazolo[3,4-b]pyrazine; Indeno[2,1-e]pyrazolo[3,4-b]pyrazin-5-one; Biological evaluation
Rational design, efficient syntheses and biological evaluation of N,N′-symmetrically bis-substituted butylimidazole analogs as a new class of potent Angiotensin II receptor blockers
Keywords: ارزیابی بیولوژیکی; AT1 receptor blockers; N,N′-Bis-alkylated butylimidazole analogs; Synthesis; Wittig reaction; Hydroxymethylation; Structure elucidation; Docking studies; Molecular dynamics; Biological evaluation
Study of the chemical chelates and anti-microbial effect of some metal ions in nanostructural form on the efficiency of antibiotic therapy “norfloxacin drug”
Keywords: ارزیابی بیولوژیکی; Norfloxacin; Nano-particles; Lanthanide(III) metals; Anti-microbial; Biological evaluation
Developing biologically active compounds having efficient DNA binding and cleavage activity: Spectroscopic investigation
Keywords: ارزیابی بیولوژیکی; Schiff base metal complexes; DNA interaction; Molecular docking; Biological evaluation
Synthesis and cytotoxic evaluation of novel paraconic acid analogs
Keywords: ارزیابی بیولوژیکی; Lactones; Paraconic acids analogs; Multicomponent reactions; Domino process; Biological evaluation; Cytotoxic activity
Novel antileukemic agents derived from tamibarotene and nitric oxide donors
Keywords: ارزیابی بیولوژیکی; Multi-target drugs; Nitric oxide; RAR agonist; Synthesis; Biological evaluation
Synthesis, crystal structures and biological evaluation of water-soluble zinc complexes of zwitterionic carboxylates
Keywords: ارزیابی بیولوژیکی; Zwitterionic carboxylates; Zinc(II) complexes; Crystal structures; DNA cleavage; Biological evaluation;
(S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(piperazin-1-yl)propanoic acid compounds: Synthesis and biological evaluation of dual PPARα/γ agonists
Keywords: ارزیابی بیولوژیکی; (S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(piperazin-1-yl)propanoic acids; Synthesis; Biological evaluation; Dual PPARα/γ agonist
Synthesis, characterization, thermal and antimicrobial studies of diabetic drug models: Complexes of vanadyl(II) sulfate with ascorbic acid (vitamin C), riboflavin (vitamin B2) and nicotinamide (vitamin B3)
Keywords: ارزیابی بیولوژیکی; Vanadyl sulfate; Vitamin C; Vitamin B2; Vitamin B3; Spectroscopic studies; Biological evaluation
Identification of a new anti-diabetic agent by combining VOSO4 and vitamin E in a single molecule: Studies on its spectral, thermal and pharmacological properties
Keywords: ارزیابی بیولوژیکی; Vanadyl sulfate; Vitamin E; Insulin; Spectroscopic studies; Biological evaluation
Hydroxyapatite nucleation and growth mechanism on electrospun fibers functionalized with different chemical groups and their combinations
Keywords: ارزیابی بیولوژیکی; Electrospun fibers; Functional groups; Hydroxyapatite nucleation; Growth mechanism; Biological evaluation