Keywords: AGO; Argonaute; ARG1; arginase1; ATM; adipose tissue macrophage; BAT; brown adipose tissue; BMDM; bone marrow derived macrophage; C/EBP; CCAAT-enhancer-binding proteins; CCL2; C-C Motif Chemokine Ligand 2; CCR2; C-C Motif Chemokine Receptor 2; CLS; crown-
مقالات ISI (ترجمه نشده)
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Keywords: Ox-LDL; oxidized low-density lipoproteins; Nat-LDL; native LDL; BMDM; bone marrow derived macrophages; ChS; cholesteryl hemisuccinate; FC; free cholesterol; LacCer; Lactosylceramide; LCCM; L929-cells conditioned medium; LUVs; large unilamellar vesicles; P
Keywords: Cross-talk; Cancer cell; Cancer-associated macrophage; Glioblastoma; Nano-drug; ATP; adenosine triphosphate; BBB; blood-brain barrier; BCA; bicinchoninic acid; BMDM; bone marrow derived macrophages; CD; cluster of differentiation; CFSE; 5(6)-carboxyfluore
Keywords: α-SMA; α-smooth muscle actin; Ang II; angiotensin II; BMDM; bone marrow-derived macrophage; DMEM; Dulbecco's modified Eagle's medium; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; IFN-γ; interferon-γ; IL-1β; interleukin-1β; IL
Keywords: BMDM; Bone Marrow-derived Macrophage; cDNA; complementary DNA; Ct; Cycle threshold; DAMP; Danger-associated Molecular Pattern; FBS; Fetal Bovine Serum; GEO; Gene Expression Omnibus; hiPS cell; human induced Pluripotent Stem cell; IFN-γ; Interferon-γ; Ig
Keywords: AA; arachidonic acid; Akt (PKB); protein kinase; BMDM; bone marrow-derived macrophages; CerK; ceramide kinase; C1P; ceramide 1-phosphate; cPLA2; calcium-dependent cytosolic phospholipase 2; ERK; extracellularly regulated kinases; GLUT; glucose transporter
Keywords: Glycopolymer; Liposome; Macrophage; Carbohydrate; CD206; macrophage mannose receptor; CD301; macrophage galactose-type lectin; CMA; cholesterol methacrylate; ManEMA-OAc; per-O-acetylated mannose ethyl methacrylate monomer; GalEMA-OAc; per-O-acetylated gal
Keywords: BMDM; bone marrow-derived macrophage; ERK 1/2; p44/42-extracellular signal-regulated kinases 1 and 2; HIF-1α; hypoxia inducible factor-1 alpha; IFN-γ; interferon-gamma; IL-6; interleukin 6; iNOS; inducible nitric oxide synthase; JAK/STAT; JAK kinases/si
Keywords: FABP; fatty acid binding protein; WT; wild type; KO; knockout; IL-10; interleukin 10; YM-1; mouse macrophage secretory glycoprotein; Fizz-1; found in inflammatory zone-1; LPS; lipopolysaccharide; IFN-γ; interferon gamma; IL-4; interleukin 4; M1; pro-infl
Keywords: Ad; adenovirus; ATF; activating transcription factor; BMDM; bone marrow-derived macrophage; bZIP; basic region leucine zipper; ERK1/2; extracellular-regulated protein kinases 1 and 2; Gal; D-galactosamine; IκB; inhibitory κB; LPS; lipopolysaccharide; NF
Keywords: 1,25 (OH)2D; 1,25-dihydroxyvitamin D; ALP; alkaline phosphatase; AVK; vitamin K antagonists; BAX; BCL2-associated X protein; BMDM; bone marrow-derived macrophage; BMP-2; bone morphogenetic protein-2; CAC; coronary artery calcifications; CAD; coronary arte
Keywords: KCs; kupffer cells; JNKs; C-Jun N-terminal kinases; MAPKs; mitogen-activated protein kinases; CCR2; C-C motif chemokine receptor 2; ATMs; Adipose tissue macrophages; HFD; high-fat diet; MLK3; mixed-lineage kinase 3; PPAR; peroxisome proliferator-activat
Keywords: Mouse Model; Gene Regulation; CD; UC; BMDM; bone marrow-derived myeloid cells; CD; Crohn's disease; cis-eQTL; cis-expression quantitative trait locus; COMMD1; copper metabolism MURR1 domain containing 1; DSS; dextran sodium sulfate; IBD; inflammatory bo
Keywords: BMDM; bone marrow-derived macrophages; CpG ODN; oligodeoxynucleotides containing unmethylated cytosine-phosphate-guanine; DMEM; Dulbecco's Modified Eagle Medium; RPMI; Roswell Park Memorial Institute; FACS; fluorescence-activated cell sorter; MFI; mean fl
Keywords: AcLDL; acetylated LDL; Apo; apolipoprotein; BMDM; bone marrow-derived macrophage; CD-36; cluster of differentiation 36; DiI; 1,1-dioctadecyl-3,3,3â²,3â²-tetramethylindocarbocyane perchlorate; THP-1; human acute monocytic leukemia cells; GAPDH; glycerald
Impaired Specific Antifungal Immunity in CARD9-Deficient Patients with Phaeohyphomycosis
Keywords: BMDM; bone marrow-derived macrophage; HK; heat-killed; KO; knockout; P1; patient 1; P2; patient 2; P3; patient 3; PBMC; peripheral blood mononuclear cell; Th; T-helper; WT; wild-type;
Aminoacyl-tRNA synthetases, therapeutic targets for infectious diseases
Keywords: ARS; aminoacyl-tRNA synthetase; TLR; toll-like receptor; RIG-I; retinoic acid-inducible gene-I; MAVS; mitochondrial antiviral signaling protein; IFN; interferon; ITCH; E3 ubiquitin-protein ligase Itchy homolog; MSC; multi-tRNA synthetase complex; AIMP; AR
Myeloid ATG16L1 does not affect adipose tissue inflammation or body mass in mice fed high fat diet
Keywords: T2D; type 2 diabetes; VAT; visceral adipose tissue; IR; insulin resistance; LFD; low fat diet; HFD; high fat diet; ATM; adipose tissue macrophage; DIO; diet induced obesity; BMDM; bone marrow derived macrophage; WT; wildtype; eWAT; epididymal white adipos
Macrophage CD31 Signaling in Dissecting Aortic Aneurysm
Keywords: aortic dissection; CD31; drug discovery; intramural hematoma; macrophages; peptides; ADIM; acute aortic dissection and intramural hematoma; Ang II; angiotensin II; Apo Eâ/â; apolipoprotein E knockout; BMDM; bone marrow-derived macrophage; IL; interl
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis
Keywords: atherosclerosis; drug development; immunology; inflammation; nanotechnology; Apoe; apolipoprotein E; BMDM; bone marrow-derived macrophage; CVD; cardiovascular disease; DC; dendritic cell; NF-κB; nuclear factor kappa-light-chain-enhancer of activated B ce
A new and efficient culture method for porcine bone marrow-derived M1- and M2-polarized macrophages
Keywords: GM-CSF; granulocyte macrophage colony-stimulating factor; M-CSF; macrophage colony-stimulating factor; moDM; monocyte-derived macrophages; BMDM; bone marrow-derived macrophages; Porcine; Macrophage; M1; M2; CD163; IL-10;
Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice
Keywords: Pancreatic Inflammation; Mechanisms; Immune Response; Mouse Model; ATP; adenosine triphosphate; BMDM; bone marrow-derived macrophages; CCK; cholecystokinin; CTSB; cathepsin B; CTSL; cathepsin L; DAMP; damage-associated molecular pattern; IL; interleukin;
Deletion of PPARγ in lung macrophages provides an immunoprotective response against M. tuberculosis infection in mice
Keywords: PPARγ; M. tuberculosis; Macrophage; PPAR; Peroxisome proliferator-activated receptor; RXR; retinoid X receptor; PPRE; PPAR response element; TB; tuberculosis; M.tb; Mycobacterium tuberculosis; CFUs; colony-forming units; DMEM; Dulbecco's Modified Eagle's
Gamma-tocotrienol attenuates the aberrant lipid mediator production in NLRP3 inflammasome-stimulated macrophages
Keywords: AA; arachidonic acid; ATM; adipose tissue macrophages; BMDM; bone marrow-derived macrophages; Cer; ceramide; COX2; cyclooxygenase 2; DAG; diacylglycerol; DAMP; damage-associated molecular pattern; Des; dihydroceramide desaturase; FFA; free fatty acid; γT
Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair
Keywords: Arg-1; arginase-1; BMDM; bone marrow-derived macrophage; IGF; insulin-like growth factor; MACS; magnetically activated cell sorting; MSCs; mesenchymal stem cells; rGPNMB; recombinant GPNMB; TNF-α; tumor necrosis factor-α; VEGF; vascular endothelial grow
Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β Responses
Keywords: ALS; amyotrophic lateral sclerosis; BMDM; bone marrow-derived macrophages; C9orf72; chromosome 9 open-reading frame 72; CNS; central nervous system; CXCL; CXC chemokine ligand; DAMPs; damage-associated molecular patterns; DMEM; Dulbecco's Modified Eagle
Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway
Keywords: AhR; aryl hydrocarbon receptor; ARNT; ah receptor nuclear translocator protein; ATP; adenosine triphosphate; ASC; apoptosis-associated speck-like protein containing CARD; BMDM; bone marrow-derived macrophage; BSA; bovine serum albumin; Caspase-1; cysteiny
BCL3 regulates RANKL-induced osteoclastogenesis by interacting with TRAF6 in bone marrow-derived macrophages
Keywords: TRAF6; tumor necrosis factor receptor-associated factor 6; BCL3; B-cell chronic lymphatic leukemia protein 3; TAK1; transforming growth factor β-activated kinase 1; RANKL; Receptor activator of nuclear factor-κB ligand; NFATC1; nuclear factor of activat
STING Signaling Promotes Inflammation in Experimental Acute Pancreatitis
Keywords: Mouse Model; Apoptosis; Signal Transduction; Innate Immunity; ACS; acinar cell culture supernatant; AP; acute pancreatitis; BM; bone marrow; BMDM; BM-derived macrophages; CDE; choline-deficient diet supplemented with DL-ethionine; cGAS; cyclic GMP-AMP syn
Protostemonine attenuates alternatively activated macrophage and DRA-induced asthmatic inflammation
Keywords: AAM; alternatively activated macrophage; AHR; airway hyperresponsiveness; Arg-1; arginase-1; BALF; bronchoalveolar; BMDM; bone marrow derived macrophage; COPD; chronic obstructive pulmonary disease; DRA; dust mites, ragweed and aspergillus; Eos; eosinophi
Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice
Keywords: Immune Regulation; Biological Clock; Acute Liver Failure; Rev-erbα; ASC; apoptosis-associated Speck-like protein containing a Caspase recruitment domain protein; ATP; adenosine triphosphate; BMDM; bone marrow-derived macrophage; ChIP; chromatin immunop
Targeting the 15-keto-PGE2-PTGR2 axis modulates systemic inflammation and survival in experimental sepsis
Keywords: 15k-PGE2; 15-keto-PGE2; 15-PGDH; 15-hydroxyprostaglandin dehydrogenase; ARE; anti-oxidant response element; BMDM; bone marrow-derived macrophages; CLP; cecum ligation/puncture; COX2; cyclooxygenase2; G6pd; glucose-6-phosphate dehydrogenase; HO-1; hemeoxyg
Liver X receptors agonists suppress NLRP3 inflammasome activation
Keywords: LXRs; liver X receptors; LXRα; NR1H3; LXRβ; NR1H2; T0901317; T09; GW3965; GW; mtROS; mitochondria reactive oxygen species; NLRP3; the NLR family pyrin domain-containing protein 3; ASC; speck-like protein containing a caspase recruitment domain; PAMP; pa
5-Lipoxygenase in monocytes emerges as a therapeutic target for intimal hyperplasia in a murine wire-injured femoral artery
Keywords: 5-LO; 5-lipoxygenase; WT; Wild-type; FLAP; 5-lipoxygenase activating protein; LT; leukotriene; ROS; reactive oxygen species; MMP; matrix metalloproteinases; DAMP; damage-associated molecular patterns; HMGB1; high mobility group box 1 protein; VSMC; vascul
mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function
Keywords: 4E-BP; eIF4E binding protein; AUC; area under the curve; BMDM; bone marrow-derived macrophages; BSA; bovine serum albumin; CLEC10a; C-type lectin domain family 10 member A; ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinases; FACS; Fluo
Macrophage phenotype in response to ECM bioscaffolds
Keywords: BMDM; Bone marrow derived macrophages; MÏ; Untreated Macrophage; UBM-ECM; Urinary Bladder Matrix; SIS-ECM; Small Intestine Submucosa; ECM; Extracellular Matrix; MIL4; Interleukin 4 exposed macrophage; MIFNg+LPS; Interferon gamma + Lipopolysaccharide ex
A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells
Keywords: IL-1β; interleukin 1-beta; IL-18; interleukin-18; LPS; lipopolysaccharide; MSU; monosodium urate crystals; Pam3CSK4; synthetic triacylated lipopeptide; BMDM; bone marrow-derived macrophage; PBMC; peripheral blood mononuclear cell; DAMP; damage-associated
Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase
Keywords: IL-1; ibrutinib; Bruton tyrosine kinase; NLRP3; inflammasome; macrophage; X-linked agammaglobulinemia; Staphylococcus aureus; Muckle-Wells syndrome; inflammation; APC; Allophycocyanin; ASC; Apoptosis-associated speck-like protein containing a CARD; BMDM;
Biological and pathophysiological roles of end-products of DHA oxidation
Keywords: PUFA; polyunsaturated fatty acids; CEP; 2-(Ï-Carboxyethyl)pyrrole; CPP; 2-(Ï-carboxypropyl)pyrrole; CHP; 2-(Ï-carboxyheptyl)pyrrole; DHA; docosahexaenoic acid; TLR; toll-like receptor; AMD; age-related macular degeneration; ROS; reactive oxygen species
Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli
Keywords: AFM; Atomic Force Microscopy; AMPs; Antimicrobial Peptides; BMDM; Bone-Marrow Derived Macrophages; CC50; 50% cytotoxicity concentrations; CFU; Colony Forming Units; CD; Circular Dichroism; DMEM; Dulbecco's Modified Eagle's Medium; DMPC; 1,2-Dimyristoyl-sn
Evaluation of protective immune response against fowl typhoid in chickens vaccinated with the attenuated strain Salmonella Gallinarum ÎcobSÎcbiA
Keywords: live vaccine; BMDM; flow cytometry; T cells; acquired immunity;
Phagocytosis of bone marrow derived macrophages is controlled by phosphoinositide 3-kinase γ
Keywords: BMDM; bone marrow derived macrophages; PI3Kγ; phosphoinositide 3-kinase gamma; PAMP; pathogen associated molecular pattern; DAMP; damage associated molecular patterns; PKA; protein kinase A; PDE; phosphodiesterase; KO; knock out; KD; kinase dead; PI3Kγ;
Macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins are modulated by complement protein C1q
Keywords: Inflammation; Atherosclerosis; Innate; LDL; JAK-STAT; PPAR; acLDL; acetylated low density lipoprotein; BMDM; bone marrow derived macrophages; GO; gene ontology; HDL; high density lipoprotein; HMDM; human monocyte derived macrophages; IFN; interferon; JAK;
E3 ubiquitin ligase NKLAM ubiquitinates STAT1 and positively regulates STAT1-mediated transcriptional activity
Keywords: NKLAM; natural killer lytic-associated molecule; STAT1; signal transducer and activator of transcription 1; RBR; RING in between RING; JAK1; Janus kinase 1; IFNγ; interferon gamma; IFNGR; interferon gamma receptor; GAS; gamma interferon activation sequen
Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling
Keywords: Ubiquitin; Innate immunity; TNF; TLR3; NOD1; LUBAC; AMSH-LP; AMSH-like protein; λ-PPase; bacteriophage λ protein phosphatase; BMDM; bone marrow-derived macrophages; JNK; c-Jun N-terminal kinase; cIAP; cellular Inhibitor of Apoptosis; DUB; deubiquitylase
Iron gene expression profile in atherogenic Mox macrophages
Keywords: acLDL; acetylated LDL; ApoEâ/â; Â cells or mice deficient in the gene coding for apolipoprotein E; ATH; atherosclerosis; BMDM; bone marrow-derived macrophages; CP/Cp; ceruloplasmin (gene Cp); EDTA; ethylenediaminetetraacetic acid; ffe; flat iron mutat
Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE
Keywords: ANA; Anti-nuclear antibodies; Axl; Axl tyrosine kinase (UFO); BMDM; Bone marrow-derived macrophages; GBM; Glomerular basement membrane disease; SLE; Systemic lupus erythematosus; PBMC; Peripheral blood mononuclear cell; SLE; Lupus; Axl; Macrophages;
Basic ScienceSoluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate
Keywords: BMDM; bone-marrow-derived macrophage; DPP-4; dipeptidyl peptidase-4; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; IκB-α; NF-kappa-B inhibitor alpha; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; M6P; mannose-6-phosphate; NO; nitric
CSF-1 receptor signalling is governed by pre-requisite EHD1 mediated receptor display on the macrophage cell surface
Keywords: CSF1R; colony stimulating factor 1 receptor; CSF1; colony stimulating factor-1; BMDM; bone marrow derived macrophage; EHD1; Eps-15 homology domain-containing protein 1; EHD1-KO; EHD1-knockout (4-hydroxytamoxifen induced deletion); RTK; receptor tyrosine k
Adenosine A2A receptor signaling attenuates LPS-induced pro-inflammatory cytokine formation of mouse macrophages by inducing the expression of DUSP1
Keywords: A2AR; adenosine A2A receptor; AP-1; activator protein 1; BLC; B-lymphocyte chemoattractant; BMDM; bone marrow derived macrophage; CREB; cAMP response element-binding protein; DUSP1; dual specific phosphatase; Epac; exchange protein activated by cAMP; ERK;