دانلود مقالات ISI درباره Boc + ترجمه فارسی

Copper(II) complexes of N3O tripodal ligands appended with pyrene and polyamine groups: Anti-proliferative and nuclease activities

Keywords: Boc; tert-ButylOxyCarbonyl; CT; Charge Transfer; CT DNA; Calf Thymus DeoxyriboNucleic Acid; CV; Cyclic Voltammetry; DFT; Density Functional theory; DMEM; Dulbecco's Modified Eagle's Medium; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; DNA; Deoxyri

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position

Keywords: Thieno[2,3-d]pyrimidine; Dithiocarbamate; Cytotoxicity; Probe; Target identification; Tubulin; Boc; tert-butyloxycarbonyl; CPT; camptothecin; DMF; N,N-dimethylformamide; DMSO; dimethyl sulphoxide; DSB; DNA double-strand break; EDCI; 1-ethyl-3-(3-dimethyla

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2018 سفارش ترجمه

Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship

Keywords: Cefiderocol; Siderophore; Siderophore cephalosporin; Multi-drug resistant Gram-negative pathogens; ESBL; extended-spectrum β-lactamase; MDR; multi-drug resistant; PG; protecting group; ACLE·HCl; (7-amino-3-chloromethyl-3-cephem-4-carboxylate p-methoxybe

دانلود رایگان متن کامل مقاله ISI 83 صفحه سال انتشار : 2018 سفارش ترجمه

Smart polymersomes and hydrogels from polypeptide-based polymer systems through α-amino acid N-carboxyanhydride ring-opening polymerization. From chemistry to biomedical applications

Keywords: ADSCs; adipose derived stem cells; AFM; atomic force microscopy; AG; l/dl-allylglycine; AIBN; 2,2′-azobisisobutyronitrile; Ala; alanine; ATR-FTIR; attenuated total reflectance Fourier transform infrared spectroscopy; ATRP; atom transfer radical polymeri

دانلود رایگان متن کامل مقاله ISI 137 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis of PET probe O6-[(3-[11C]methyl)benzyl]guanine by Pd0-mediated rapid C-[11C]methylation toward imaging DNA repair protein O6-methylguanine-DNA methyltransferase in glioblastoma

Keywords: MGMT; O6-methylguanine-DNA methyltransferase; TMZ; temozolomide; O6-BG; O6-benzylguanine; PET; positron emission tomography; AGT; O6-alkylguanine-DNA alkyltransferase; TFA; trifluoroacetyl; [11C]mMeBG; 11C-labeled O6-[(3-methyl)benzyl]guanine; BOC; tert-b

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery and evaluation of Cav3.2-selective T-type calcium channel blockers

Keywords: AcOH; acetic acid; Boc; tert-butylocycarbonyl; DIPEA; N,N-diisopropylethylamine; DMAP; 4-(dimethylamino)pyridine; DMF; N,N-dimethylformamide; EDC·HCl; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt; hydroxybenzotriazole; KHMDS; potassi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) - An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity

Keywords: AdoMet; S-adenosyl-l-methionine; AdoMetDC; S-adenosylmethionine decarboxylase; BBB; bloodbrain barrier; Boc; tert-butoxycarbonyl; BSA; N,O-bis(trimethylsilyl)acetamide; CNS; central nervous system; DEAD; diethyl azodicarboxylate; DIAD; diisopropyl azodica

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists

Keywords: FXR; farnesoid X receptor; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; SHP; small heterodimer partner; RXRα; retinoid X receptor α; 9-cis-RA; 9-cis-retinoic acid; LBD; ligand binding domain; TR-FRET; time-resolved fluorescence reso

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Insight into the role of urotensin II-related peptide tyrosine residue in UT activation

Keywords: BRET; bioluminescence resonance energy transfer; ACN; acetonitrile; Bip; biphenylalanine; Boc; tert-butoxycarbonyle; BOP; (Benzotriazol-1-yloxy)tris(dimethylamino) phosphonium hexafluorophosphate; CHO cells; Chinese Hamster Ovary cells; DCM; dichlorometha

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A PEGylated analog of short-length Neuromedin U with potent anorectic and anti-obesity effects

Keywords: Neuromedin U (NMU); NMU-8; Polyethylene glycol (PEG); Diabetes; Obesity; NMU; neuromedin U; PEG; polyethyleneglycol; PipAc; 2-(piperazin-1-yl)acetic acid; CNS; central nervous system; DIO; diet-induced obesity; EMCS; N-(6-maleimidocaproyloxy)succinimide;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and evaluation of novel ureido/thioureido derivatives of amino acid conjugated 2,3-dichlorophenyl piperazine as highly potent antiglycating agents

Keywords: AGE; advanced glycation end products; Boc; t-butoxycarbonyl; BSA; bovine serum albumin; EDCI; 1-(3-dimethylaminopropyl)-3-ethyl-carbodiimide·HCl; HOBt; 1-hydroxybenzotriazole; NMM; N-methyl morpholine; PBS; phosphate buffer saline; PZN; 1-(2,3-dichloroph

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel somatostatin receptor subtype 5 (SSTR5) antagonists: Pharmacological studies and design to improve pharmacokinetic profiles and human Ether-a-go-go-related gene (hERG) inhibition

Keywords: Boc; tert-butoxycarbonyl; Pd(OAc)2; palladium acetate; PBu3; tributylphosphine; DIBAL-H; diisobutylaluminum hydride; S-phos; 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl; Pd2(dba)3; tris(dibenzylideneacetone) dipalladium; NaH; sodium hydride; LiAlH

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

A Sonic hedgehog coreceptor, BOC regulates neuronal differentiation and neurite outgrowth via interaction with ABL and JNK activation

Keywords: Shh; Sonic hedgehog; BOC; Brother of CDO; CDO; cell adhesion molecular downregulated by ocogenes; JNK; Jun N-terminal kinase; EC; embryonal carcinoma cell; NPC; neural progenitor cell; DCC; deleted in colorectal cancer; ROBO; roundabout; GLI; glioma-assoc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and biological activity of cyclolinopeptide A analogues modified with γ4-bis(homo-phenylalanine)

Keywords: Boc; tert-Butoxycarbonyl; C8; octyl stationary phase; C18; octadecyl stationary phase; CLA; cyclolinopeptide A; COSY-DQF; double quantum filtered proton spin correlation; CsA; cyclosporine A; DIPEA; N,N-diisopropylethylamine; DMF; dimethylformamide; DMSO;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents

Keywords: Ac; acetyl; ADME; absorption, distribution, metabolism, and excretion; aq.; aqueous; AUC; total area under the blood concentration-time curve; bid; bis in die (twice per day); Boc; (tert-butoxy)carbonyl; Bu; butyl; Bz; benzoyl; cLogP; calculate logarith

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

A review on unitized regenerative fuel cell technologies, part B: Unitized regenerative alkaline fuel cell, solid oxide fuel cell, and microfluidic fuel cell

Keywords: AEM; Anion exchange membrane; AFC; Alkaline fuel cell; ASR; Area specific resistance; BCY; Yttrium-doped barium cerate; BCZY; Yttrium-doped barium cerate zirconate; BCZYbCo; BaCe0.48Zr0.40Yb0.10Co0.02O3−δ; BHC; Bifunctional Hydrogen Catalyst; BHE; Bifu

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Stereoselective synthesis of modified cysteines

Keywords: Alloc; allyloxycarbonyl; Ar; aryl; Bn; benzyl; Cbz; benzyloxycarbonyl; Cbz-OSu; benzyloxycarbonylsuccinimide; NBS; N-bromosuccinimide; Boc; tert-butoxycarbonyl; m-CPBA; m-chloroperbenzoic acid; DABCO; 1,4-diazabicyclo[2.2.2]octane; DBU; 1,8-diazabicyclo[5

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Cobalt-based paramagnetic probe to study RNA-protein interactions by NMR

Keywords: NCp7; Nucleocapsid protein 7; HSQC; Heteronuclear single quantum coherence; PRE; Paramagnetic resonance enhancement; TLC; Thin layer chromatography; NMR; Nuclear magnetic resonance; RNA; Ribonucleic acid; A; Adenosine; C; Cytidine; U; Uridine; G; Guanosin

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities

Keywords: Nek2 inhibitors; Imidazo[1,2-a]pyridine; Antitumor activity; Selectivity; Nek2; NIMA-related kinase 2; Nlp; ninein-like protein; SAC; spindle assembly checkpoint; Mad1/2; mitotic arrest deficient 1/2; Hec1; highly expressed in cancer 1; CIN; chromosome in

دانلود رایگان متن کامل مقاله ISI 106 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity

Keywords: Macrolide antibiotics; Macrolide resistance; Acylides; Structure-activity relationships; Antibacterial activity; Heck reaction; MLSB; macrolide-lincosamide-streptogramin B; Mef; macrolide efflux; SAR; structure-activity relationships; DABCO; 1,4-diazabicy

دانلود رایگان متن کامل مقاله ISI 130 صفحه سال انتشار : 2017 سفارش ترجمه

The missing links to link ubiquitin: Methods for the enzymatic production of polyubiquitin chains

Keywords: Ubiquitin; Post-translational modification; Ligation; Enzymatic ubiquitination; Ubiquitinating enzymes; Protein purification; Ub; ubiquitin; ATP; adenosine triphosphate; YUH1; yeast protease Ub hydrolase-1; DTT; dithiothreitol; EDTA; ethylenediaminetetraa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Metallography and fuel cladding chemical interaction in fast flux test facility irradiated metallic U-10Zr MFF-3 and MFF-5 fuel pins

Keywords: Metallography; Fuel cladding chemical interaction; Irradiated fuel pins; MFF; FFTF; BOC; beginning of cycle; BOL; beginning of life; DFR; Dounreay fast reactor; EBR; experimental breeder reactor; EFPD; effective full power day; EOC; end of cycle; FCCI; fu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Core design optimization and analysis of the Purdue Novel Modular Reactor (NMR-50)

Keywords: SMR; small modular reactor; NMR; Novel Modular Reactor; BOC; beginning of cycle; EOC; end of cycle; VC; void coefficient; MCPR; minimum critical power ratio; MFLPD; maximum fuel linear power density; SDM; shutdown margin; PMAXS; Purdue Macroscopic Cross-S

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

l-tryptophan and dipeptide derivatives for supercoiled plasmid DNA purification

Keywords: NMR; nuclear magnetic resonance; STD; Saturation Transfer Difference; HR-MAS; high resolution magic angle spinning; SPR; surface plasmon resonance; 5´-GMP; guanosine 5′-monophosphate; 3´-AMP; adenosine 5′-monophosphate; 5´-TMP; thymidine 5′-monop

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and antiproliferative activity of two diastereomeric lignan amides serving as dimeric caffeic acid-l-DOPA hybrids

Keywords: WTDRDQBEARUVNC-LURJTMIESA-N; GGCBRMCAJQAIEZ-ZENAZSQFSA-N; GPZFXSWMDFBRGS-UXONFWTHSA-N; XEMOVRYQMGXSLS-LVDDQXARSA-N; UMTWRITYTCPWIR-FHZBLKBXSA-N; UMTWRITYTCPWIR-UQDURWBFSA-N; WFGNJLMSYIJWII-FJXQXJEOSA-N; VURIGNDVTSFLOU-JTQLQIEISA-N; WNTNRJOSPPCGFR-DEOSSOPV

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

A review on unitized regenerative fuel cell technologies, part-A: Unitized regenerative proton exchange membrane fuel cells

Keywords: ATO; Sb-doped SnO2; BHC; Bifunctional hydrogen catalyst; BOC; Bifunctional oxygen catalyst; BOP; Balance of plant; BPPs; Bipolar plates; EC; Electrolysis cell; FC; Fuel cell; GDB; Gas diffusion backing; GDE; Gas diffusion electrode; GDL; Gas diffusion lay

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

An update on the stereoselective synthesis of γ-amino acids

Keywords: ABO; 2,7,8-trioxabicyclo[3.2.1]octane; Ac; acetyl; ACPECA; 4-aminocyclopent-2-ene-1-carboxylic acid; AHPPA; 4-amino-3-hydroxy-5-phenylpentanoic acid; AMCP; 2-(aminomethyl)-cyclopentanecarboxylic acid; APCH; 2-(1-aminopropyl)cyclohexanecarboxylic acid; APT

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2016 سفارش ترجمه

Hedgehog receptor function during craniofacial development

Keywords: Sonic hedgehog; Craniofacial development; Disease; Holoprosencephaly; Dispatched; Scube2; Patched1; Patched2; Gas1; Cdon; Boc; Lrp2/megalin; Gpr161; Smoothened; EvC1/2;

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2016 سفارش ترجمه

Achievement of regioselectivity in transition metal-catalyzed direct C-H (hetero)arylation reactions of heteroarenes with one heteroatom through the use of removable protecting/blocking substituents or traceless directing groups

Keywords: Chemoselectivity; Regioselectivity; Direct C-H (hetero)arylation; Transition metal catalysts; Removable groups; Traceless directing groups; Deprotection; Ac; acetyl; acac; acetylacetonate; 1-Ad; 1-adamantyl; AIBN; azobisisobutyronitrile; Ar; aryl; Boc;

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M1 agonists

Keywords: KOQVBYSCBCRVQJ-SVUXJTORSA-N; GPCR; G protein-coupled receptors; CHO; Chinese hamster ovary; GTPγ35S; [35S]-guanosine-5′-O-(3-thio)triphosphate; BOC; butoxycarbony; EC50; half maximal effective concentration of drug; pKa; log of acid dissociation consta

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives

Keywords: ACN; Acetonitrile; Boc; tert-butyloxycarbonyl; CHO; Chinese hamster ovary; DCM; Dichloromethane; DIPEA; N,N-Diisopropylethylamine; DALEA; [D-Ala2, Leu5] enkephalin amide; DAMGO; [D-Ala2,NMePhe4,Gly5-ol]enkephalin; Dmt; 2,6-dimethyltyrosine; DPDPE; c[D-Pen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Synthetic study of peptide aldehyde via acetal/thioacetal transformation: application for Lys/Ser-containing peptides

Keywords: Peptide aldehyde; Acetal; Thioacetal; Cysteine protease inhibitor; SPPS; solid phase peptide synthesis; NBS; N-bromo succinimide; SARS; severe acute respiratory syndrome; DMF; dimethyl formamide; DIPEA; diisopropylethylamine; DIPC; diisopropylcarbodiimide

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Cyclen-based double-tailed lipids for DNA delivery: Synthesis and the effect of linking group structures

Keywords: Boc; tert-butoxycarbonyl; cyclen; 1, 4, 7, 10-tetraazacyclododecane; lipoplexes; liposome/DNA complexes; TE; gene transfection efficiency; EDC HCl; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt; 1-hydroxybenzotriazole; TFA; trifluoroac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Design of novel 3,6-diazabicyclo[3.1.1]heptane derivatives with potent and selective affinities for α4β2 neuronal nicotinic acetylcholine receptors

Keywords: 3,6-diazabicyclo[3.1.1]heptanes; Synthesis; α4β2 neuronal nicotinic acetylcholine receptors selectivity; Agonism; Antagonism; CNS; central nervous system; nAChRs; nicotinic acetylcholine receptors; ACh; acetylcholine; GABA; gamma amino butyric acid; Trp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Novel type of plasmin inhibitors: Providing insight into P4 moiety and alternative scaffold to pyrrolopyrimidine

Keywords: MMP; matrix metalloproteinase; UK; urokinase; pNA; para-nitroanilide; MCA; 7-amino-4-methyl-coumarin amide; Boc; t-butoxycarbonyl; Pyr; pyroglutamic acid; Plasmin inhibitors; Benzimidazole; Scaffold; Pyrrolopyrimidine; P4 moiety; Structure-activity rela

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Improving the in situ measurement of RTD response times through Discrete Wavelet Transform in NPP

Keywords: DWT; Discrete Wavelet Transform; RTD; Resistance Temperature Detector; PWR; Pressurized Water Reactor; AR; autoregressive; NPP; Nuclear Power Plant; NRC; Nuclear Regulatory Commission; PSD; Power Spectral Density; MRA; Multi Resolution Analysis; STFT; Sho

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis of a mixed-model stationary phase derived from glutamine for HPLC separation of structurally different biologically active compounds: HILIC and reversed-phase applications

Keywords: HPLC; high-performance liquid chromatography; RPLC; reversed-phase liquid chromatography; NPLC; normal-phase liquid chromatography; HILIC; hydrophilic interaction chromatography; DCC; dicyclohexylcarbodiimide; DCM; dichloromethane; H; hexane; EtOAc; ethyl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Blood-brain transfer and antinociception of linear and cyclic N-methyl-guanidine and thiourea-enkephalins

Keywords: Blood-brain barrier (BBB) transport (influx/efflux); Antinociceptive activity; Linear/cyclic enkephalin analogs; In vivo mouse models; AUC; area under the curve; Alloc; allyloxycarbonyl; BBB; blood-brain barrier; Boc; tertButyloxycarbonyl; BSA; bovine

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological evaluation of new C-10 substituted dithranol pleiotropic hybrids

Keywords: AAPH; 2,2-azobis(2-amidinopropane) dihydrochloride; Boc; tert-butyloxycarbonyl; DPPH; 1,1-diphenyl-2-picrylhydrazyl radical; ET; single electron transfer; FCC; Flash Column Chromatography; HAT; hydrogen atom transfer; LOX; lipoxygenase; MTT; 3-(4,5-dimeth

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Distinct structural requirements for CDON and BOC in the promotion of Hedgehog signaling

Keywords: CDON; BOC; Neural patterning; Hedgehog; Co-receptor;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

BN/CC isosterism in borazaronaphthalenes towards phosphodiesterase 10A (PDE10A) inhibitors

Keywords: cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Boc; tert-butyloxycarbonyl; THF; tetrahydrofuran; DMF; dimethylformamide; CPME; cyclopentyl methyl ether; TFA; trifluoroacetic acid; EDCI; 1-ethyl-3-(3-dimethylaminopropyl)carbodi

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Novel benzidine and diaminofluorene prolinamide derivatives as potent hepatitis C virus NS5A inhibitors

Keywords: HCV; NS5A inhibitor; Benzidine; Diaminofluorene; Structure-activity relationship; HCV; hepatitis C virus; Peg-IFNα; pegylated interferon α; SVR; sustained virological response; GT1a; hepatitis C virus genotype 1a, a subtype of hepatitis C virus genoty

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

VERONA V6.22 - An enhanced reactor analysis tool applied for continuous core parameter monitoring at Paks NPP

Keywords: 2D; two dimensional; 3D; three dimensional; AEKI; Atomic Energy Research Institute (Budapest, Hungary); BOC; beginning of cycle; CFD; computational fluid dynamics; CFX; widely used CFD code; C-PORCA; nodal diffusion code (used for core calculations at Pak

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Binding cooperativity between a ligand carbonyl group and a hydrophobic side chain can be enhanced by additional H-bonds in a distance dependent manner: A case study with thrombin inhibitors

Keywords: Cooperativity; Protein-ligand binding; Ligand binding affinity; Scoring functions; B-factor; Thrombin; Non-additivity; Me; methyl; Bn; benzyl; Boc; tert-butoxycarbonyl; ΔG˚; standard Gibbs free energy; Ki; inhibition constant; EDCI; 1-(3-dimethylaminopr

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease

Keywords: CVB3; Cosxackievirus B3; CVB3 3Cpro; Cosxackievirus B3 3C protease; FRET; fluorescence resonance energy transfer; l-DOPA; levodopa; Boc; tert-butyloxycarbonyl; TFA; trifluoroacetic acid; DCM; dichloromethane; IC50; the half maximal inhibitory concentratio

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

An update on the stereoselective synthesis of α-aminophosphonic acids and derivatives

Keywords: α-Aminophosphonic acids; α-Aminophosphonates; Stereoselective synthesis; Three-component reaction; ABSA; 4-acetamidobenzenesulfonyl azide; Abu; aminobutyric acid; Ac; acetyl; ACE; angiotensin-converting enzyme; Ala; alanine; Ar; aryl; BINAP; 2,2′-bis(

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2015 سفارش ترجمه

The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: Highly selective cytotoxic agents

Keywords: Neocryptolepine; Antiproliferative activity; Antifungal activity; Biofilm; Guanidine group; Mechanism of action; Apoptosis; Hemolytic activity; Boc; tert-butyloxycarbonyl group; BSTU; N,N′-bis-Boc-thiourea; DIPEA; N,N-diisopropylethylamine; DMF; dimethy

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2015 سفارش ترجمه

Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: Study of 6-substituted pyridine-3-boronic acid derivatives

Keywords: Boronic acids; Pyridine derivatives; Antimicrobial agents; Efflux pump inhibitors; Staphylococcus aureus; a.u.; arbitrary unit; Boc; tert-butoxycarbonyl; n-BuLi; n-butyllithium; EPI; efflux pump inhibitor; EtBr; ethidium bromide; MFS; major facilitator su

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of novel small molecule CCR2 antagonists: Evaluation of 4-aminopiperidine derivatives

Keywords: AcOH; acetic acid; Boc; tert-butyloxycarbonyl; CCL2; chemokine ligand 2; CCR2; chemokine receptor 2; DCE; dichloroethane; DCM; dichloromethane; DIPEA; N,N-diisopropylethylamine; DMAP; N,N-dimethylaminopyridine; DMSO; dimethylsulfoxide; INCB3344; N-(2-(((3

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets

Keywords: Peptides; Conjugation; Antimicrobial; Antiglycation; Urease inhibition; H+/K+-ATPase activity; ANSA; 1-amino-2-naphthol-4-sulphonic acid; Bis-PNPC; bis(4-nitrophenyl)carbonate; Boc; tert-butyloxycarbonyl; DCM; dichloromethane; EGTA; ethylene glycol tetraa

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه