Synthesis of PET probe O6-[(3-[11C]methyl)benzyl]guanine by Pd0-mediated rapid C-[11C]methylation toward imaging DNA repair protein O6-methylguanine-DNA methyltransferase in glioblastoma

Synthesis of PET probe O6-[(3-[11C]methyl)benzyl]guanine by Pd0-mediated rapid C-[11C]methylation toward imaging DNA repair protein O6-methylguanine-DNA methyltransferase in glioblastoma

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 9, 1 May 2017, Pages 1892-1896

Hiroko Koyama, Hiroshi Ikenuma, Hiroshi Toda, Goro Kondo, Masaki Hirano, Masaya Kato, Junichiro Abe, Takashi Yamada, Toshihiko Wakabayashi, Kengo Ito, Atsushi Natsume, Masaaki Suzuki,