Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Skeletal muscle injury; Macrophage activation; M1/M2; Muscle regeneration; BMMac; Bone marrow-derived macrophages; CCL2; CC chemokine ligand 2; CCR2; CC chemokine receptor type 2; ECM; Extracellular matrix; IFN-γ; Interferon gamma; IGF-1; Insulin-like gr
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Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; PARP; poly(ADP-ribose) polymerase; SH3BP2; SH3 domain-binding protein 2; BMMs; bone marrow-derived macrophages; WT; wild-type; MNCs; multinucleated cells; CBP; CREB-binding protein; OIM; osteogenic induction medium; Tankyrase; SH3BP2; Osteoclastogenesis;
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; DT; diphtheria toxin; DTR; diphtheria toxin receptor; WT; wild type; LLC; Lewis lung carcinoma; TAMs; tumor-associated macrophages; BM; bone marrow; BMDMs; bone marrow-derived macrophages; BMD; bone mineral density; HSCs; hematopoietic stem cells; CD169+
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; AA; arachidonic acid; AMs; alveolar macrophages; BAL; bronchoalveolar lavage; BM; bone marrow; BMDMs; bone marrow-derived macrophages; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; DHA; docosahexaenoic acid; G-CSF; granul
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; MNCs; multinucleated cells; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor-κB ligand; M-CSF; macrophage colony stimulating factor; OPG; osteoprotegerin; c-fms; colony-stimulating factor-1 receptor; ERK; extracellul
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; AA; arachidonic acid; Akt (PKB); protein kinase; BMDM; bone marrow-derived macrophages; CerK; ceramide kinase; C1P; ceramide 1-phosphate; cPLA2; calcium-dependent cytosolic phospholipase 2; ERK; extracellularly regulated kinases; GLUT; glucose transporter
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; ALT; alanine aminotransferase; BMDMÏ; bone marrow-derived macrophages; CARS; coherent anti-Stokes Raman scattering; C/EBPα; CCAAT/enhancer binding protein (C/EBP) alpha; C/EBPβ; CCAAT/enhancer binding protein (C/EBP) beta; FasL; Fas ligand; FFA; free f
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Akt; protein kinase B; BMDMs; bone marrow-derived macrophages; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CCL; chemokine (C-C motif) ligand; CCR; C-C motif receptor; CD; cluster of differentiation; ConA; concanavalin A; CTL; cyto
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; KCs; kupffer cells; JNKs; C-Jun N-terminal kinases; MAPKs; mitogen-activated protein kinases; CCR2; C-C motif chemokine receptor 2; ATMs; Adipose tissue macrophages; HFD; high-fat diet; MLK3; mixed-lineage kinase 3; PPAR; peroxisome proliferator-activat
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; AIF; apoptosis-inducing factor; AMPK; AMP kinase; Apaf-1; apoptotic protease activating factor; BMM; bone marrow-derived macrophages; cFLIP; cellular FLICE-like inhibitory protein; cIAP; cellular inhibitor of apoptosis protein; COX; cyclooxygenase; CTL; c
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; BMDM; bone marrow-derived macrophages; CpG ODN; oligodeoxynucleotides containing unmethylated cytosine-phosphate-guanine; DMEM; Dulbecco's Modified Eagle Medium; RPMI; Roswell Park Memorial Institute; FACS; fluorescence-activated cell sorter; MFI; mean fl
Mycobacterium tuberculosis ESAT6 induces IFN-β gene expression in Macrophages via TLRs-mediated signaling
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; RD1; Region of difference 1; ESAT6; 6-kDa early secretory antigen target; ESX-1; ESAT6 system-1; CFP10; 10-kDa culture filtrate protein; Type I IFNs; Type I interferons; TBK1; TANK-binding kinase; IRF; Interferon regulatory factor; BMDMs; Bone marrow-deri
ALK is required for NLRP3 inflammasome activation in macrophages
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; ALK; Macrophage; Inflammasome; NF-κB; Lipid peroxidation; PAMP; pathogen-associated molecular pattern molecule; DAMP; damage-associated molecular pattern molecule; NLRP3; NLR family pyrin domain containing; PYCARD; PYD and CARD doma0069n containing; ATP;
Synergistic effect of co-stimulation of membrane and endosomal TLRs on chicken innate immune responses
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; TLR; toll like receptor; TLR-Ls; toll-like receptor ligands; BMMs; bone marrow-derived macrophages; PCSK; pam3Cys-SK4; MPLA; synthetic monophosphoryl lipid A; KLA; Di[3-deoxy-d-manno-octulosonyl]-lipid A ammonium salt; R848; resiquimod; CpG; cytosine-phos
Src promotes anti-inflammatory (M2) macrophage generation via the IL-4/STAT6 pathway
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Macrophage polarization; Inflammation; Src; STAT6; Arg1; Arginase; BMDMs; Bone Marrow-Derived Macrophages; C/EBPβ; CCAAT/enhancer-binding Protein beta; CREB; cAMP-Response Element Binding protein; DSS; Dextran Sulfate Sodium; Fizz1; Found in inflammatory
Anti-inflammatory properties of GLPss58, a sulfated polysaccharide from Ganoderma lucidum
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; BMMs; Bone marrow-derived macrophages; MSLs; mouse spleen lymphocytes; mAb; monoclonal antibody; SLC; secondary lymphoid tissue chemokine; SPR; surface plasmon resonance; HPBL; shuman peripheral blood lymphocytes; LN; lymph node; Sulfated polysaccharide;
Decoy peptides derived from the extracellular domain of toll-like receptor 2 (TLR2) show anti-inflammatory properties
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; BMDMs; Bone marrow-derived macrophages; LPS; Lipopolysaccharide; MAPK; Mitogen-activated protein kinase; NF-kB; Nuclear factor-kB; P3, -Pam3CSK4; S-[2,3-Bis(palmitoyloxy)propyl]-N-palmitoyl-l-cysteinyl-l-seryl-l-lysyl-l-lysyl-l-lysyl-l-lysine; P2 -Pam2CSK
The citrus flavanone naringenin reduces gout-induced joint pain and inflammation in mice by inhibiting the activation of NFκB and macrophage release of IL-1β
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Naringenin; Gout arthritis; Pain; Inflammation; NFκB; Inflammasome; ABTS; 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonate; ALT; alanine transaminase; ASC; apoptosis-associated speck-like protein containing a CARD; AST; aspartate transaminase; BMDMs; bone
Hydrogen sulfide attenuates oxidative stress-induced NLRP3 inflammasome activation via S-sulfhydrating c-Jun at Cys269 in macrophages
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; ANOVA; analysis of variance; BMM; bone marrow-derived macrophages; BSA; bovine serum albumin; CVD; cardiovascular diseases; DAPI; 4â²,6-diamidino-2-phenylindole; DMSO; dimethyl sulphoxide; DHE; dihydroethidium; EDTA; ethylenediaminetetraacetic acid; FBS;
A new and efficient culture method for porcine bone marrow-derived M1- and M2-polarized macrophages
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; GM-CSF; granulocyte macrophage colony-stimulating factor; M-CSF; macrophage colony-stimulating factor; moDM; monocyte-derived macrophages; BMDM; bone marrow-derived macrophages; Porcine; Macrophage; M1; M2; CD163; IL-10;
Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Pancreatic Inflammation; Mechanisms; Immune Response; Mouse Model; ATP; adenosine triphosphate; BMDM; bone marrow-derived macrophages; CCK; cholecystokinin; CTSB; cathepsin B; CTSL; cathepsin L; DAMP; damage-associated molecular pattern; IL; interleukin;
Gamma-tocotrienol attenuates the aberrant lipid mediator production in NLRP3 inflammasome-stimulated macrophages
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; AA; arachidonic acid; ATM; adipose tissue macrophages; BMDM; bone marrow-derived macrophages; Cer; ceramide; COX2; cyclooxygenase 2; DAG; diacylglycerol; DAMP; damage-associated molecular pattern; Des; dihydroceramide desaturase; FFA; free fatty acid; γT
Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β Responses
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; ALS; amyotrophic lateral sclerosis; BMDM; bone marrow-derived macrophages; C9orf72; chromosome 9 open-reading frame 72; CNS; central nervous system; CXCL; CXC chemokine ligand; DAMPs; damage-associated molecular patterns; DMEM; Dulbecco's Modified Eagle
MicroRNA-155 induces autophagy in osteoclasts by targeting transforming growth factor β-activated kinase 1-binding protein 2 upon lipopolysaccharide stimulation
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; BMM; bone marrow-derived macrophages; M-CSF; macrophage-colony stimulating factor; miR; microRNA; miR-155; microRNA-155; MNC; multinucleated cells; OC; osteoclast; PBS; phosphate-buffered saline; qPCR; quantitative polymerase chain reaction; RANKL; recept
The SGK1 inhibitor EMD638683, prevents Angiotensin II-induced cardiac inflammation and fibrosis by blocking NLRP3 inflammasome activation
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; SGK1; serum-glucocorticoid regulated kinase 1; Ang II; Angiotension II; IL; interleukin; TGF-β; transforming growth factor-β; CTGF; connective tissue growth factor; TNF-α; tumor necrosis factor-α; IFN-γ; Interferon-γ; ASC; apoptosis associated speck
Targeting the 15-keto-PGE2-PTGR2 axis modulates systemic inflammation and survival in experimental sepsis
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; 15k-PGE2; 15-keto-PGE2; 15-PGDH; 15-hydroxyprostaglandin dehydrogenase; ARE; anti-oxidant response element; BMDM; bone marrow-derived macrophages; CLP; cecum ligation/puncture; COX2; cyclooxygenase2; G6pd; glucose-6-phosphate dehydrogenase; HO-1; hemeoxyg
M2b macrophage polarization accompanied with reduction of long noncoding RNA GAS5
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Macrophage polarization; Bone marrow-derived macrophages; Long noncoding RNA GAS5; Nonsense-mediated RNA decay;
Macrophage C-type lectin is essential for phagosome maturation and acidification during Escherichia coli-induced peritonitis
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; MCL; E. coli-induced peritonitis; Macrophage; Bacterial killing; Phagosome maturation; Phagosome acidification; MCL; macrophage C-type lectin; CLRs; C-type lectin receptors; CRD; carbohydrate recognition domains; PRRs; pattern recognition receptors; TLRs
Crocin inhibits RANKL-induced osteoclast formation and bone resorption by suppressing NF-κB signaling pathway activation
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; RANKL; receptor activator of NF-κB ligand; BMMs; bone marrow-derived macrophages; Osteoclastogenesis; RANKL; Crocin; Antioxidant; NF-κB;
Safflower bud inhibits RANKL-induced osteoclast differentiation and prevents bone loss in ovariectomized mice
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Safflower bud; RANKL; Osteoclast differentiation; Ovariectomized mice; Osteoporosis; BMDMs; bone marrow-derived macrophages; DC STAMP; dendritic cell-specific transmembrane protein; MAPK; mitogen activated protein kinase; M-CSF; macrophage colony-stimulat
DNA repair and systemic lupus erythematosus
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; 8-oxoG; 8-hydroxyguanosine; OGG1; 8-oxoguanine DNA glycosylase; ARTD1; ADP-ribosyltransferase diphtheria toxin-like 1; ATM; Ataxia telangiectasia mutated; BER; base excision repair; BMDMs; bone marrow-derived macrophages; CSR; lass switch recombination; C
IL-17 contributes to the pathogenesis of obliterative bronchiolitis via regulation of M1 macrophages polarization in murine heterotopic trachea transplantation models
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; OB; obliterative bronchiolitis; H&E; hematoxylin-eosin; HTT; heterotopic trachea transplantation; KO; knock-out; LPS; lipopolysaccharide; WT; wild-type; BMDMs; bone marrow-derived macrophages; IL-17; Macrophages; Obliterative bronchiolitis; Trachea transp
mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; 4E-BP; eIF4E binding protein; AUC; area under the curve; BMDM; bone marrow-derived macrophages; BSA; bovine serum albumin; CLEC10a; C-type lectin domain family 10 member A; ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinases; FACS; Fluo
Ameloblastin and enamelin prevent osteoclast formation by suppressing RANKL expression via MAPK signaling pathway
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Enamel-related gene products; Ameloblastin; Enamelin; RANKL; receptor activator of nuclear factor kappa-B ligand; 1,25(OH)2D3; 1,25-dihydroxy-vitamin D3; DEX; dexamethasone; MAPK; mitogen-activated protein kinase; ERK1/2; extracellular-signal-regulated ki
Enhanced immunostimulatory activity of in silico discovered agonists of Toll-like receptor 2 (TLR2)
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; AG; agonist; BMDMs; bone marrow-derived macrophages; DC; dendritic cell; LPS; lipopolysaccharide; NF-kB; nuclear factor-kB; Pam3CSK4; S-[2,3-Bis(palmitoyloxy)propyl]-N-palmitoyl-l-cysteinyl-l-seryl-l-lysyl-l-lysyl-L-lysyl-l-lysine; Pam2CSK4; S-[(2R)-2,3-B
Cisplatin-induced necroptosis in TNFα dependent and independent pathways
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; RIP; receptor-interacting protein; MLKL; mixed lineage kinase domain-like protein; CypD; cyclophilin-D; ROS; reactive oxygen species; mPTP; mitochondrial permeability transition pore; TNFα; tumor necrosis factor α; CaMKII; Ca2 +-calmodulin-dependent pr
The role of nucleotide-binding oligomerization domain 1 during cytokine production by macrophages in response to Mycobacterium tuberculosis infection
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; BMDMs; bone marrow-derived macrophages; CARDs; caspase recruitment domains; LRRs; leucine-rich repeats; Nod1; nucleotide-binding oligomerization domain 1; PRR; spattern recognition receptors; Cytokines; Innate immune response; Macrophages; Nod1;
Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; AGEs; advanced glycation end products; DN; diabetic nephropathy; TAK1; TGF-β-activated kinase 1; BMMs; bone marrow-derived macrophages; MAPKs; mitogen-activated protein kinases; NF-κB; nuclear factor kappa B protein; MCP-1; monocyte chemo-attractant pro
Proteasome inhibitor PS-341 limits macrophage necroptosis by promoting cIAPs-mediated inhibition of RIP1 and RIP3 activation
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; PS-341; Macrophage; Necroptosis; Apoptosis; BMDMs; bone marrow-derived macrophages; cIAPs; cellular inhibitor of apoptosis proteins; RIP1; receptor interacting protein 1; RIP3; receptor interacting protein 3; TNF; tumor necrosis factor;
MicroRNAs: New regulators of IL-22
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of
Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Ubiquitin; Innate immunity; TNF; TLR3; NOD1; LUBAC; AMSH-LP; AMSH-like protein; λ-PPase; bacteriophage λ protein phosphatase; BMDM; bone marrow-derived macrophages; JNK; c-Jun N-terminal kinase; cIAP; cellular Inhibitor of Apoptosis; DUB; deubiquitylase
Iron gene expression profile in atherogenic Mox macrophages
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; acLDL; acetylated LDL; ApoEâ/â; Â cells or mice deficient in the gene coding for apolipoprotein E; ATH; atherosclerosis; BMDM; bone marrow-derived macrophages; CP/Cp; ceruloplasmin (gene Cp); EDTA; ethylenediaminetetraacetic acid; ffe; flat iron mutat
Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; ANA; Anti-nuclear antibodies; Axl; Axl tyrosine kinase (UFO); BMDM; Bone marrow-derived macrophages; GBM; Glomerular basement membrane disease; SLE; Systemic lupus erythematosus; PBMC; Peripheral blood mononuclear cell; SLE; Lupus; Axl; Macrophages;
Layer-by-layer nanocoating of live Bacille-Calmette-Guérin mycobacteria with poly(I:C) and chitosan enhances pro-inflammatory activation and bactericidal capacity in murine macrophages
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Bacille Calmette-Guérin (BCG); Bone marrow-derived macrophages; Layer-by-layer nanocoating; Nitric oxide (NO); Polyinosinic-polycytidylic acid (poly(I:C)); BCG; Bacille Calmette-Guérin; CFU; colony forming units; LbL; Layer-by-layer; PAMPs; Pathogen-ass
Superparamagnetic iron oxide nanoparticle uptake alters M2 macrophage phenotype, iron metabolism, migration and invasion
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; AD; Aminodextran; APS; 3-aminopropyl-triethoxysilane; BMM; Bone marrow-derived macrophages; BMM-M2; Bone marrow-derived macrophages polarised to M2; DMSA; Dimercaptosuccinic acid; DMT-1; Divalent metal transporter-1; ERK; Extracellular signal-regulated ki
Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; BMDMs; bone marrow-derived macrophages; c-di-GMP; cyclic diguanylate monophosphate; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; FBS; fetal bovine serum; GST; Glutathione S-transferase; HEK293T; human embryonic kidney; IB; immunobl
A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKβ
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; 4E-BP1; eukaryotic translation initiation factor 4E-binding protein; BMDM; bone marrow-derived macrophage; CM; conditioned medium; DMEM; Dulbecco's modified essential medium; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylen
Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; ASMase; acid sphingomyelinase; BMDMs; bone marrow-derived macrophages; C1P; ceramide 1-phosphate; M-CSF; macrophage colony stimulating factor; MTS; [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulphophenyl)-2H-tetrazolium, inner salt]; SP
Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; BMC; bone marrow cells; BMM; bone marrow-derived macrophages; DMEM; Dulbecco's modification of Eagle's medium; FBS; fetal bovine serum; HFD; high fat diet; HFD-MetS; high-fat-diet induced metabolic syndrome; miRNA; microRNA; miR-144; microRNA 144; NAFLD;
P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages
Keywords: ماکروفاژها حاصل از استخوان مغز استخوان; Interleukin-1; P2X7R; Dendritic cells; Macrophages; A-740003; ATP; adenosine triphosphate; BM; bone marrow; BMM; bone marrow-derived macrophages; DAMPs; danger associated molecular patterns; DC; dendritic cells; DMSO; dimethyl sulfoxide; EDTA; ethylene di