دانلود مقالات ISI درباره ژن BRCA1 + ترجمه فارسی

Regulation of epithelial to mesenchymal transition by BRCA1 in breast cancer

Keywords: ژن BRCA1; BRCA1; epithelial to mesenchymal transition; Drug resistance; Breast cancer; Metastasis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Beyond interstrand crosslinks repair: contribution of FANCD2 and other Fanconi Anemia proteins to the replication of DNA

Keywords: ژن BRCA1; A-EJ; alternative end joing; APH; aphidicolin; BIR; break induced replication; BTRR; BLM helicase/topoisomerase IIIa (TOPOIIIa)/RMI1 and RMI2 cofactors; CFS; common fragile sites; Cis; cisplatin; DEB; diepoxybutane; DSBs; double strand breaks; DSEs; one e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Systematic review of the empirical investigation of resources to support decision-making regarding BRCA1 and BRCA2 genetic testing in women with breast cancer

Keywords: ژن BRCA1; BRCA1; BRCA2; Breast cancer; Decision aid; Decision support; Treatment-focused genetic testing;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Radiosensitization by the PARP inhibitor olaparib in BRCA1-proficient and deficient high-grade serous ovarian carcinomas

Keywords: ژن BRCA1; PARP inhibitor; Radiosensitization; Radiotherapy; BRCA1; HGSOC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair

Keywords: ژن BRCA1; CDK4/6; cyclin-dependent kinases 4 and 6; CDK2; cyclin-dependent kinase 2; iCDK4/6; inhibitor of CDK4/6; LEE011; inhibitor of CDK4/6, ribociclib, Kisqali; PD0332991; inhibitor of CDK4/6, palbociclib, Imbrance; NU6140; cyclin-dependent kinase 2 (CDK2) inhi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

BRCA1 Mutation Status and Follicular Fluid Exposure Alters NFκB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells

Keywords: ژن BRCA1; ACHP; 2-amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile; BRCA1; breast cancer 1, early onset; BRCA2; breast cancer 2, early onset; EGFR; epidermal growth factor receptor; FBS; fetal bovine serum; FDR; false discov

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer

Keywords: ژن BRCA1; BRCA1; breast cancer susceptibility gene 1; BRCA2; breast cancer susceptibility gene 2; CCOC; clear cell ovarian carcinoma; DAB; 3,3′-diaminobenzidine; ENOC; endometrioid ovarian carcinoma; EOC; epithelial ovarian cancer; HGSOC; high-grade serous ovaria

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway

Keywords: ژن BRCA1; ARE; antioxidative response element; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; BRCA1; breast cancer susceptibility protein 1; BRCT; BRCA1 C-terminal; BER; base excision repair; CaMKII; calcium/calmodulin-dependent protein kinase II; CNS;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Human sirtuin 3 (SIRT3) deacetylates histone H3 lysine 56 to promote nonhomologous end joining repair

Keywords: ژن BRCA1; DNA repair; HDACs; 53BP1; BRCA1; Nuclear sirtuin; γH2AX;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Variation of exon 11 of the BRCA1 gene in patients with familial breast cancer at Mohammed VI center for treatment of cancers

Keywords: ژن BRCA1; BC; breast cancer; BRCA1; breast cancer gene 1; PCR; Polymerase Chain Reaction; Family breast cancer; BRCA1; Exon 11; Clinical; Pathological;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

GIT2-A keystone in ageing and age-related disease

Keywords: ژن BRCA1; AD; Alzheimer's disease; ArfGAP; ADP-ribosylation factor GTPase-activating proteins; AT; adipose tissue; ATM; Ataxia Telangiectasia Mutated; ATP; adenosine tri-phosphate; BRCA1; breast cancer type 1 susceptibility protein; CNS; central nervous system; D

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

BRCA1 and BRCA2 expression patterns and prognostic significance in digestive system cancers

Keywords: ژن BRCA1; BRCA1; BRCA2; Cancer; Digestive system; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

BRCA1 mutation spectrum, functions, and therapeutic strategies: The story so far

Keywords: ژن BRCA1; Breastcancer; BRCA1; Mutations; DNA damage repair;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Assessment of the expression of the BRCA1, BRCA2, TP53, MDM2, BAX and CASP-3 genes in normal and tumor tissues for patients with breast cancer in Morocco

Keywords: ژن BRCA1; Breast cancer; BRCA1; TP53; BAX; CASP-3; Tumor;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Hyperthermia-mediated drug delivery induces biological effects at the tumor and molecular levels that improve cisplatin efficacy in triple negative breast cancer

Keywords: ژن BRCA1; Thermosensitive liposome; Drug delivery; Hyperthermia; Cisplatin; BRCA1; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Phytoestrogens and mycoestrogens interacting with breast cancer proteins

Keywords: ژن BRCA1; AUC; area under the curve; BRCA1; breast cancer 1; BRCA2; breast cancer 2, CAT, catalase; DHT; dihydrotestosterone; EDCs; endocrine disrupting chemicals; ERBB2; human epidermal growth factor receptor 2; ERBBs; epidermal growth factor receptor family; ER-b

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

BRCA1/BRCA2 Germline Mutation Carriers and Sporadic Pancreatic Ductal Adenocarcinoma

Keywords: ژن BRCA1; BRCA1; breast cancer 1; BRCA2; breast cancer 2; DFS; disease-free survival; HR; hazard ratio; NGS; next-generation sequencing; OS; overall survival; PDAC; pancreatic ductal adenocarcinoma; VUS; variants of unknown significance; WT; BRCA1/BRCA2 wild-type;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Specific detection of stable single nucleobase mismatch using SU-8 coated silicon nanowires platform

Keywords: ژن BRCA1; Microarray platform; Silicon nanowires; SU-8; APTES-GAD; BRCA1; Biochip specificity;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Epigenetics of breast cancer: Biology and clinical implication in the era of precision medicine

Keywords: ژن BRCA1; BC; breast Cancer; ER; estrogen Receptor; PgR,PR; progesteron receptor; HER-2; human epidermal growth factor receptor 2; TNBC; triple negative breast cancer; ncRNA; non coding RNA; CpG(s); cytosine-phosphate-guanine dinucleotide(s); 5-me-C; 5-methyl-cytos

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Comprehensive BRCA mutation analysis in the Greek population. Experience from a single clinical diagnostic center

Keywords: ژن BRCA1; BRCA1; BRCA2; Next Generation Sequencing (NGS); Multiplex Ligation-dependent Probe Amplification (MLPA); Greece;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits

Keywords: ژن BRCA1; BRCA1; BRCA2; Methylation; Loss of heterozygosity; Tumor cell percentage;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance

Keywords: ژن BRCA1; ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

The poly(ADP-ribose) polymerase inhibitor olaparib induces up-regulation of death receptors in primary acute myeloid leukemia blasts by NF-κB activation

Keywords: ژن BRCA1; PARP1; Lynparza; AML; FAS; TRAIL receptors; BRCA1; DNA repair associated; BRCA2; DNA repair associated; DR4; TNF receptor superfamily member 10a (TNFRSF10A); DR5; TNF receptor superfamily member 10b (TNFRSF10B); DSBs; DNA double strand breaks; FAS; Fas ce

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Discusión ética y legal del asesoramiento genético en paciente portadora de una variación patológica en RAD51D

Keywords: ژن BRCA1; RAD51D; Cáncer hereditario de mama; Cáncer hereditario de ovario; BRCA1; BRCA2; Asesoramiento genético; Aspectos ético-legales; RAD51D; Hereditary breast cancer; Hereditary ovarian cancer; BRCA1; BRCA2; Genetic counselling; Ethical-legal aspects;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Cancer de la prostate et gènes de réparation de l'ADN

Keywords: ژن BRCA1; BRCA2; BRCA1; Dépistage ciblé; Inhibiteur de PARP; Sur-incidence; BRCA1; BRCA2; Specific screening; PARP inhibitor; Over-incidence;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

BRCA1 reversion mutation acquired after treatment identified by liquid biopsy

Keywords: ژن BRCA1; Ovarian serous carcinoma; BRCA1; Olaparib; Comprehensive genomic profiling;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewRegulation of repair pathway choice at two-ended DNA double-strand breaks

Keywords: ژن BRCA1; DSB; NHEJ; HR; Two-ended DSB; BRCA1; 53BP1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

BRCA1 and BRCA2 mutation predictions using the BRCAPRO and Myriad models in Korean ovarian cancer patients

Keywords: ژن BRCA1; BRCA1; BRCA2; Risk models; BRCAPRO; Myriad BRCA risk calculator;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

BRCA1 promoter methylation in peripheral blood cells and predisposition to breast cancer

Keywords: ژن BRCA1; BRCA1; Breast cancer; Epigenetic; Epigenetic modification; Methylation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Cell cycle arrest mediated by Cd-induced DNA damage in Arabidopsis root tips

Keywords: ژن BRCA1; CDKs; Cyclin-dependent kinases; CYCB1;1; Cyclin B1;1; qRT-PCR; Real time quantitative reverse transcription-polymerase chain reaction; BRCA1; Breast cancer susceptibility1; PCNA; Proliferation cell nuclear antigen; DSB; Double strand break; GR1; Gamma res

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleRapid selection of BRCA1-proficient tumor cells during neoadjuvant therapy for ovarian cancer in BRCA1 mutation carriers

Keywords: ژن BRCA1; BRCA1; Ovarian cancer; Neoadjuvant therapy; Loss-of-heterozygosity; Treatment resistance; HRM; high-resolution melting; IDS; interval debulking surgery; IHC; immunohistochemistry; LOH; loss-of-heterozygosity; NACT; neoadjuvant chemotherapy; OC; ovarian ca

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

ESR1 single nucleotide polymorphism rs1062577 (c.*3804T > A) alters the susceptibility of breast cancer risk in Iranian population

Keywords: ژن BRCA1; ATM; ataxia-telangiectasia mutated; BRCA1; BReast CAncer gene 1; BRCA2; BReast CAncer gene 2; CHECK2; checkpoint kinase 2; ER; estrogen receptor; ESR1; estrogen receptor 1; HER2; human epidermal growth factor 2; PR; progesterone receptor; PTEN; phosphatas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Higher antitumor activity of trabectedin in germline BRCA2 carriers with advanced breast cancer as compared to BRCA1 carriers: A subset analysis of a dedicated phase II trial

Keywords: ژن BRCA1; Trabectedin; Lurbinectedin; Breast cancer; BRCA1; BRCA2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Multigene panels in Ashkenazi Jewish patients yield high rates of actionable mutations in multiple non-BRCA cancer-associated genes

Keywords: ژن BRCA1; Multigene panels; BRCA1; BRCA2; Ashkenazi Jewish; Cancer genetics;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Mortality reduction and cost-effectiveness of performing hysterectomy at the time of risk-reducing salpingo-oophorectomy for prophylaxis against serous/serous-like uterine cancers in BRCA1 mutation carriers

Keywords: ژن BRCA1; Risk-reducing salpingo-oophorectomy; Hysterectomy; Cost-effectiveness; BRCA1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Biochemical and biophysical characterization of ruthenation of BRCA1 RING protein by RAPTA complexes and its E3 ubiquitin ligase activity

Keywords: ژن BRCA1; Breast cancer; Ruthenium complexes; E3 ubiquitin ligase; BRCA1; BRCA1 dysfunction; Zinc finger protein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Endoplasmic reticulum-mitochondria Ca2 + crosstalk in the control of the tumor cell fate

Keywords: ژن BRCA1; AIF; apoptosis-inducing factor; ASC; adaptor apoptosis-associated speck-like protein containing CARD; BRCA1; breast/ovarian cancer susceptibility gene 1; ER; endoplasmic reticulum; ERp44; ER resident protein 44; FACL4; long-chain fatty acid-CoA ligase typ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original ResearchRisk of uterine cancer for BRCA1 and BRCA2 mutation carriers

Keywords: ژن BRCA1; Uterine cancer; Endometrial cancer; BRCA1; BRCA2; Risk-reducing surgery; Oophorectomy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

PerspectiveDNA-Damage Response RNA-Binding Proteins (DDRBPs): Perspectives from a New Class of Proteins and Their RNA Targets

Keywords: ژن BRCA1; 53BP1; tumor protein p53 binding protein 1; AGO2; Argonaute 2; ATM; ataxia telangiectasia mutated; BRCA1; breast cancer 1; DDR; DNA-damage response; DDRBP; DNA-damage response RNA-binding protein; DDSR1; DNA-damage-sensitive RNA 1; diRNA; double-strand-br

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Exceptionally high UBE2C expression is a unique phenomenon in basal-like type breast cancer and is regulated by BRCA1

Keywords: ژن BRCA1; UBE2C; ubiquitin-conjugating enzyme 2C; BBC; basal-like breast cancer; HR; hazard ratio; P-gp; P-glycoprotein; MRP1; multidrug resistance protein 1; BCRP; breast cancer resistance protein; SD; standard deviation; Breast cancer; UBE2C; BRCA1; Doxorubicin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Mainstreaming cancer genetics: A model integrating germline BRCA testing into routine ovarian cancer clinics

Keywords: ژن BRCA1; BRCA1; BRCA2; Genetic testing; Mainstreaming; Ovarian cancer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

¿CÓMO PUEDO MODIFICAR MI RIESGO A DESARROLLAR CÁNCER, CUANDO SOY PORTADOR DE UNA MUTACIÓN?

Keywords: ژن BRCA1; BRCA1; BRCA2; Síndrome de Lynch; Síndrome hereditario de mama y ovario; manejo; vigilancia; BRCA1; BRCA2; Lynch syndrome; Hereditary breast and ovary syndrome; treatment; surveillance;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Prognosis of patients with BRCA1-associated ovarian carcinomas depends on TP53 accumulation status in tumor cells

Keywords: ژن BRCA1; Ovarian cancer; Prognosis; BRCA1; TP53 accumulation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of AGR2 expression via 3'UTR shortening

Keywords: ژن BRCA1; 3'UTR; 3' untranslated region; AGR2; Anterior Gradient 2; BRCA1; Breast cancer 1; HPRT1; Hypoxanthine phosphoribosyltransferase 1; mTOR; Mechanistic target of rapamycin; TORC1; protein complex containing at least TOR (target of rapamycin) and Raptor (

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original ResearchOnline self-test identifies women at high familial breast cancer risk in population-based breast cancer screening without inducing anxiety or distress

Keywords: ژن BRCA1; Breast cancer; Population screening; BRCA1; BRCA2; Hereditary; Risk; Familial risk assessment; Genetic counselling; Distress; Prevention;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A label-free electrochemical DNA biosensor for breast cancer marker BRCA1 based on self-assembled antifouling peptide monolayer

Keywords: ژن BRCA1; BRCA1; Peptide; Self-assembled monolayer; Antifouling biosensor; Electrochemical impedance spectroscopy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleRecurrent large genomic rearrangements in BRCA1 and BRCA2 in an Irish case series

Keywords: ژن BRCA1; BRCA1; BRCA2; large genomic rearrangement; hereditary breast and ovarian cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Suggestion of BRCA1 c.5339T>C (p.L1780P) variant confer from 'unknown significance' to 'Likely pathogenic' based on clinical evidence in Korea

Keywords: ژن BRCA1; Breast neoplasm; BRCA1; Missense mutation; Ovarian neoplasm;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

BRCA mutation genetic testing implications in the United States

Keywords: ژن BRCA1; BRCA1; BRCA2; Genetic testing; Timing; Hereditary breast cancer; Prophylactic mastectomy; Prophylactic oophorectomy; PARP inhibitors; Platinums;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity

Keywords: ژن BRCA1; HCAR1; hydroxycarboxylic acid receptor 1; GPCR; G-protein coupled receptor; BRCA1; breast cancer type 1 susceptibility protein; NBS1; Nijmegen breakage syndrome 1; PRKDC; protein kinase DNA-activated catalytic polypeptide; DNA-PKcs; DNA-dependent protein

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه