Keywords: کتهفسین ک; BMD; bone mineral density; BV/TV; bone volume fraction; BS; bone surface; BFR/BS; bone formation rate/bone surface; CFU-F; CFU-fibroblast; CFU-Ob; CFU-osteoblast; Car2; carbonic anhydrase II; CTSK; cathepsin K; DFO; deferoxamine mesylate; FPN1; ferroporti
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Keywords: کتهفسین ک; ECM; extracellular matrix; MMPs; matrix metalloproteases; CatK; cathepsin K; AGE; advanced glycation end products; GAGs; glycosaminoglycans; Collagen; Matrix metalloproteinases; Cathepsins; Advanced glycation products; Mineralization; Proteolysis;
Keywords: کتهفسین ک; Akt2; RAC-β serine/threonine-protein kinase; AR; aldose reductase; Bcl-2; B-cell lymphoma 2; CFL1; cofilin 1;; cMDH1; cytosolic NAD-dependent malate dehydrogenase 1; CTSK; cathepsin K; Cu-Zn SOD; Cu/Zn superoxide dismutase; DHAR2; dehydroascorbate reduct
Keywords: کتهفسین ک; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; CatK; cathepsin K; CXCR4; C-X-C receptor type 4; DLL4; Delta-like ligand 4; GSC; glioma stem cell; EC; endothelial cell; ECM; extracellular matrix; GM-CSF; granulocyte/macrophage colony-stimu
Keywords: کتهفسین ک; ALP; alkaline phosphatase; Bcl-2; B-cell lymphoma 2; CTSK; cathepsin K; Dlx5; distal less homeobox5; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; LIPUS; low-intensity pulsed ultrasound; OCN; osteocalcin; PMAIP; phorbol-12-myristate-13-acetate-induced
Keywords: کتهفسین ک; BMD; bone mineral density; BMSC; Bone marrow stromal cell; Col1a1; collagen type 1 alpha-1; CTSK; cathepsin K; CTx; cross-linked type I collagen; HDL; high density lipoprotein; HFD; high-fat diet; LDL; low density lipoprotein; LDLRâ/â; Low-density lip
Keywords: کتهفسین ک; MNCs; multinucleated cells; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor-κB ligand; M-CSF; macrophage colony stimulating factor; OPG; osteoprotegerin; c-fms; colony-stimulating factor-1 receptor; ERK; extracellul
Keywords: کتهفسین ک; Postmenopausal Osteoporosis; Long-term-Treatment; Bisphosphonate; Denosumab; Romosozumab; Cathepsin K;
Keywords: کتهفسین ک; Intermittent exercise; Night shift worker; Cathepsin S; Cathepsin L; Cathepsin K; Adhesion molecules;
Keywords: کتهفسین ک; Osteoporosis; Antiresorptive; Anabolic; Cathepsin K; Sclerostin
Keywords: کتهفسین ک; cathepsin K; odanacatib; sclerostin; romosozumab; blosozumab; denosumab; teriparatide; PTHrP; osteoporosis; fractures
Keywords: کتهفسین ک; bone formation; bone resorption; osteoporosis; cathepsin K; PTHrP; sclerostin
Keywords: کتهفسین ک; α-MEM; α-minimal essential medium; APC; allophycocyanin; BMC; bone marrow cells; BRC; bone remodeling compartment; Car2; carbonic anhydrase 2; CMP; common myeloid progenitors; Ctsk; cathepsin K; FBS; fetal bovine serum; GAPDH; glyceraldehyde 3-phosphate
Keywords: کتهفسین ک; Osteoclast; Resorption; Mineral; Collagen; Cathepsin K;
Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation
Keywords: کتهفسین ک; Macrophage; Osteoclast; RANK; RANKL; NFATc1; Necrostatin-7; RANK; receptor activator of nuclear factor-kappa B; RANKL; RANK ligand; M-CSF; macrophage colony-stimulating factor; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated ki
The regulation of sclerostin by cathepsin K in periodontal ligament cells
Keywords: کتهفسین ک; Sclerostin; Cathepsin K; Hypoxia; Lysosome;
Transcriptomic hallmarks of bone remodelling revealed by RNA-Seq profiling in blood of Arabian horses during racing training regime
Keywords: کتهفسین ک; ACAP2; Arf-GAP with coiled-coil; ACLY; ATP citrate lyase; ADCY9; adenylate cyclase 9; AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta; ARFGEF2; ADP ribosylation factor guanine nucleotide exchange factor 2; ARHGEF6; Rho guanine nucleotide excha
1-α,25-dihydroxyvitamin D3 potentiates avian osteoclast activation by increasing the formation of zipper-like structure via Src/Rac1 signaling
Keywords: کتهفسین ک; Osteoclast; 1α,25-(OH)2D3; Src; Rac1; Activation; Zipper-like structure; SPF; specific pathogen free; MEM; minimum eagle medium; TRAP; tartrate-resistant acid phosphatase; CaII; carbonic anhydrase 2; Ck; cathepsin K; Mmp-9; matrix metallopeptidase 9; Rac
Gene expression analysis of Ruditapes philippinarum haemocytes after experimental Perkinsus olseni zoospore challenge and infection in the wild
Keywords: کتهفسین ک; Manila clam; Perkinsosis; Oligo-microarray; Immune response; Host-parasite interaction; A2ML1; Alpha-2-macroglobulin; ABL1; Tyrosine-protein kinase abl1; ACTA2; Alpha-2 actin; ACTB; Beta-actin; ALG1; Chitobiosyldiphosphodolichol beta-mannosyltransferase;
Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation
Keywords: کتهفسین ک; Cathepsin K; Collagen type I; LAIR-1; Leukocyte receptor complex; NFATc1; Osteoclast;
Manipulation of osteoclastogenesis: Bioactive multiphasic silica/collagen composites and their effects of surface and degradation products
Keywords: کتهفسین ک; Silica/collagen composite; Osteoclast; Resorption; TRAP; Cathepsin K;
RANKL, Ephrin-Eph and Wnt10b are key intercellular communication molecules regulating bone remodeling in autologous transplanted goldfish scales
Keywords: کتهفسین ک; RANKL; receptor activator of NF-κB ligand; RANK; receptor activator of nuclear factor κB; TRAP; tartrate-resistant acid phosphatase; NFATC1; Nuclear factor of activated T cells C1; CTSK; cathepsin K; OC-Stamp; osteoclast stimulatory transmembrane protei
Flavonoids from the roots of Artocarpus heterophyllus
Keywords: کتهفسین ک; Structure elucidation; Isoprenylated flavonoids; Artocarpus heterophyllus; Cathepsin K;
Role of cathepsin K in the development of chronic subdural hematoma
Keywords: کتهفسین ک; Cathepsin K; Cerebrospinal fluid; Chronic inflammation; Chronic subdural hematoma; Hypoxia;
Ancestral benzo[a]pyrene exposure affects bone integrity in F3 adult fish (Oryzias latipes)
Keywords: کتهفسین ک; AcvR1b; activating receptor type 1b; ALP; alkaline phosphatase; APC; adenomatous polyposis coli; ATF4; activating transcription factor 4; BaP; benzo[a]pyrene; BMD; bone mineral density; BMP2; bone morphogenetic protein 2; Col2a1b; collagen 2a1b; Col10; co
Daily chemical evodiamine from Chinese prickly ash attenuates osteoclast differentiation through RANKL induced NFAT pathways
Keywords: کتهفسین ک; CTSK; cathepsin K; NFATc1; nuclear factor of activated T cells cytoplasmic 1; TRAP, Acp5; tartrate resistant acid phosphatase; DC-STAMP; dendrite cell-specific transmembrane protein; CTR; calcitonin receptor; OSCAR; osteoclast associated and immunoglobuli
Original contributionAngiomyomatous hamartoma of lymph nodes, revisited: clinicopathologic study of 21 cases, emphasizing its distinction from lymphangioleiomyomatosis of lymph nodesâ
Keywords: کتهفسین ک; Angiomyomatous hamartoma; Lymph node; Cathepsin K; HMB-45; Lymphangioleiomyomatosis;
Cathepsin S inhibition changes regulatory T-cell activity in regulating bladder cancer and immune cell proliferation and apoptosis
Keywords: کتهفسین ک; Treg; regulatory T-cell; CatS; cathepsin S; CatK; cathepsin K; CatL; cathepsin L; PD-L1; programmed death ligand 1; PTEN; phosphatase and tensin homolog; TLR7; toll-like receptor-7; WT; wild-type; TUNEL; terminal deoxynucleotidyl transferase-mediated dUTP
Expression of Cathepsin K in Skull Base Chordoma
Keywords: کتهفسین ک; Cathepsin K; Chordoma; Invasiveness; Prognosis; Skull base; EL; Expression level; MRI; Magnetic resonance imaging; OS; Overall survival; PFS; Progression-free survival; SBC; Skull base chordoma;
C2K77 ELISA detects cleavage of type II collagen by cathepsin K in equine articular cartilage
Keywords: کتهفسین ک; Cathepsin K; Type II collagen; ELISA; Osteoarthritis; Cartilage; MMPs;
MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases
Keywords: کتهفسین ک; 7ACC2; 7-(N-benzyl-N-methylamino)-2-oxo-2H-chromene-3-carboxylic acid; BM; bone metastases; CM; conditioned medium; CTSK; cathepsin K; ECAR; extracellular acidification rate; FCCP; carbonyl cyanide 4-trifluoromethoxy phenylhydrazone; GLUT1; glucose transp
Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells
Keywords: کتهفسین ک; CatK; cathepsin K; CXCR4/7; C-X-C receptor type 4/7; GBM; glioblastoma; GSLC; glioma stem-like cell; HIF-1α; hypoxia-inducible factor-1α; HSC; hematopoietic stem cell; IHC; immunohistochemistry; SDF-1α; stromal-derived factor-1α; VEGF; vascular endoth
Decreased Cathepsin K Plasma Level may Reflect an Association of Osteopoenia/Osteoporosis with Coronary Atherosclerosis and Coronary Artery Calcification in Male Patients with Stable Angina
Keywords: کتهفسین ک; Stable angina; Calcification; Osteopoenia/osteoporosis; Cathepsin K; Osteocalcin
JiangTang XiaoKe granule attenuates cathepsin K expression and improves IGF-1 expression in the bone of high fat diet induced KK-Ay diabetic mice
Keywords: کتهفسین ک; JiangTangXiaoKe (JTXK); KK-Ay diabetic mice; Bone ash coefficient; Alkaline phosphatase (ALP); Insulin growth factor-1 (IGF-1); Cathepsin K
Early cathepsin K degradation of type II collagen in vitro and in vivo in articular cartilage
Keywords: کتهفسین ک; Type II collagen; Cathepsin K; Neoepitope; Horse; Cartilage; Protease;
Pharmacological inhibition of cathepsin K: A promising novel approach for postmenopausal osteoporosis therapy
Keywords: کتهفسین ک; CatK; cathepsin K; ODN; odanacatib; BMD; bone mineral density; DXA; dual X-ray absorptiometry; RANKL; receptor activator of nuclear factor kappB ligand; OP; osteoporosis; OA; osteoarthritis; MBD; metastatic bone disease; DHT; p-dihydrotanshinone; CTx/CTX;
Secretion of PDGF isoforms during osteoclastogenesis and its modulation by anti-osteoclast drugs
Keywords: کتهفسین ک; Osteoclast; PDGF; S1P; Cathepsin K; Odanacatib; Bone remodeling
Catepsina K como biomarcador de afectación ósea en la enfermedad de Gaucher tipo 1
Keywords: کتهفسین ک; Enfermedad de Gaucher; Remodelado óseo; Daño óseo; Biomarcador; Catepsina KGaucher disease; Bone remodelling; Bone damage; Biomarkers; Cathepsin K
Cathepsin K as a biomarker of bone involvement in type 1 Gaucher disease
Keywords: کتهفسین ک; Gaucher disease; Bone remodeling; Bone damage; Biomarkers; Cathepsin K; Enfermedad de Gaucher; Remodelado óseo; Daño óseo; Biomarcador; Catepsina K;
Effect of SI-591, a new class of cathepsin K inhibitor with peptidomimetic structure, on bone metabolism in vitro and in vivo
Keywords: کتهفسین ک; OP; Osteoporosis; CTX-I; C-terminal crosslinking telopeptide of type I collagen; BGP; Bone Gla protein; BMD; Bone mineral density; PTH; Parathyroid hormone; TRAP; Tartrate-resistant acid phosphatase; OVX; Ovariectomized; DEXA; Dual energy X-ray absorptiom
Celastrol attenuates bone erosion in collagen-Induced arthritis mice and inhibits osteoclast differentiation and function in RANKL-induced RAW264.7
Keywords: کتهفسین ک; ALT; aminotransferase; CIA; collagen-Induced arthritis; Ctr; calcitonin receptor; Ctsk; cathepsin K; CM; culture medium; MAPK; mitogen-activated protein kinases; Mmp-9; matrix metallopeptidase 9; M-CSF; macrophage colony-stimulating factor; IP; intraperit
An adult osteopetrosis model in medaka reveals the importance of osteoclast function for bone remodeling in teleost fish
Keywords: کتهفسین ک; Osteoclasts; Osteoblasts; Vertebra; Vertebral centra; Vertebral arch; Cathepsin K; Osteoporosis; Osteopetrosis
Inhibitory effects of ursolic acid on osteoclastogenesis and titanium particle-induced osteolysis are mediated primarily via suppression of NF-κB signaling
Keywords: کتهفسین ک; Ursolic acid; Osteoclastogenesis; NF-κB; Titanium particle; Osteolysis; AP-1; activator protein-1; BV/TV; bone volume/tissue volume; BMD; bone mineral density; BMC; bone mineral content; BMMs; bone marrow monocytes; CK; cathepsin K; CT; computed tomograp
Complexity of cancer protease biology: Cathepsin K expression and function in cancer progression
Keywords: کتهفسین ک; Cancer; Cathepsin K; Invasion; Metastasis; Glioma stem-like cell;
Picnodisostosis: una rara enfermedad con fracturas frecuentes
Keywords: کتهفسین ک; Picnodisostosis; Fractura atÃpica; Osteoclastos; Catepsina K; Pycnodysostosis; Atypical fracture; Osteoclast; Cathepsin K;
Diversity of proton pumps in osteoclasts: V-ATPase with a3 and d2 isoforms is a major form in osteoclasts
Keywords: کتهفسین ک; V-ATPase; vacuolar-type ATPase; RANKL; receptor activator of nuclear factor kappa B ligand; M-CSF; macrophage-colony stimulating factor; GST; glutathione S-transferase; DTT; dithiothreitol; EDTA; ethylenediamine-N,N,Nâ²,Nâ²-tetraacetic acid; Cath K; cat
Effects of eight-month treatment with ONO-5334, a cathepsin K inhibitor, on bone metabolism, strength and microstructure in ovariectomized cynomolgus monkeys
Keywords: کتهفسین ک; CATHEPSIN K; ONO-5334; Bone mineral density; Bone metabolism; Bone strength;
Interleukin-1β promotes the LC3-mediated secretory function of osteoclast precursors by stimulating the Ca2+-dependent activation of ERK
Keywords: کتهفسین ک; IL-1β; Cathepsin K; Intracellular Ca2+; LC3; Osteoclast;
Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone
Keywords: کتهفسین ک; 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d
Increased fracture callus mineralization and strength in cathepsin K knockout mice
Keywords: کتهفسین ک; Osteoclast; Osteoblast; Fracture healing; Cathepsin K; Closed stabilized fracture model;