دانلود مقالات ISI درباره Cccdna + ترجمه فارسی

پیشرفت های اخیر در درمان سرطان سلول های سرطانی

Recent advances in hepatocellular carcinoma therapy

Keywords: AASLD; American Association for the Study of the Liver Disease; AFP; α-fetoprotein; ALT; alanine aminotransferase; AST; aspartase aminotransferase; AFP-L3; agglutinin reactive fraction of AFP; cccDNA; covalently closed circular DNA; CTL; cytotoxic T lymp

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

درمان های جدید برای رسیدن به درمان کاربردی: رویکردهای ویروالوگرافی

New treatments to reach functional cure: Virological approaches

Keywords: Hepatitis B virus (HBV); Viral targets; Direct acting agents (DAA); HBV cure; cccDNA;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

نسخه های معکوس ویروسی

Viral reverse transcriptases

Keywords: AIDS; acquired immune deficiency syndrome; ALV; avian leukosis virus; AMV; avian myeloblastosis virus; APOBEC; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like; ASLV; avian sarcoma leukosis virus; AZT; 3′ -azido-3′ -deoxythymidine; BIV;

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه

الگوریتم درمان برای مدیریت عفونت ویروس هپاتیت مزمن در ایالات متحده: به روز رسانی 2015

A Treatment Algorithm for the Management of Chronic Hepatitis B Virus Infection in the United States: 2015 Update

Keywords: Hepatitis B; Guidelines; Antiviral Therapy; Peginterferon alfa-2a; Entecavir; Tenofovir; Resistance; AFP; alpha-fetoprotein; ALT; alanine aminotransferase; anti-HBc; antibody to hepatitis B core antigen; anti-HBe; antibody to hepatitis B e antigen; anti-H

دانلود رایگان متن کامل مقاله ISI 105 صفحه سال انتشار : 2015 سفارش ترجمه

St6gal1 knockdown alters HBV life cycle in HepAD38 cells

Keywords: Hepatitis B virus; N-glycan; Sialylated N-glycan; Complex-type N-glycan; HBV; Hepatitis B virus; SVP; Sub-viral particle; WT; Wild-type; Tet(+); Tetracycline-supplemented; Tet(−); Tetracycline-free; ER; Endoplasmic reticulum; St6gal1; β-galactoside α2

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Viral Hepatitis: Knowledge and Treatments for Hepatitis B and C Virus and Associated Transplantation and Neoplasia

Keywords: cccDNA; covalently closed circular DNA; HBV; hepatitis B virus; HCV; hepatitis C virus;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Predictive role of serum HBsAg and HBcrAg kinetics in patients with HBeAg-negative chronic hepatitis B receiving pegylated interferon-based therapy

Keywords: cccDNA; Chronic hepatitis B; HBcrAg; HBsAg; Hepatitis B core-related antigen; Hepatitis B virus; Pegylated interferon; Predictor; Stopping rule; Treatment response;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Tumor suppressor ZHX2 restricts hepatitis B virus replication via epigenetic and non-epigenetic manners

Keywords: HBV cccDNA; Transcription factor; Epigenetic regulation; ZHX2; Zinc finger and homeoboxes 2; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; HBcAg; hepatitis B core antigen;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

The potential and challenges of CRISPR-Cas in eradication of hepatitis B virus covalently closed circular DNA

Keywords: CHB; chronic hepatitis B; HBV; hepatitis B virus; NA; nucleos(t)ide analogue; cccDNA; covalently closed circular DNA; guide RNA; gRNA; NTCP; sodium taurocholate cotransporting polypeptide; RC-DNA; relaxed circular DNA; pgRNA; pregenomic RNAs; HBsAg; HBV s

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Advances with using CRISPR/Cas-mediated gene editing to treat infections with hepatitis B virus and hepatitis C virus

Keywords: HBV; HCV; CRISPR/Cas; cccDNA; Gene therapy;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of Slug and SOX7 as transcriptional repressors binding to the hepatitis B virus core promoter

Keywords: HBV; Slug; SOX7; Hepatocytes; Liver; Transcription; HNF4α; pgRNA; cccDNA; Promoter; Repression;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism

Keywords: TLR7; GS-9620; Hepatitis B virus; Interferon-alpha; cccDNA; Interferon-stimulated gene; MHC; Immunoproteasome; APOBEC; Smc5/6;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Hepatitis B virus: The challenge of an ancient virus with multiple faces and a remarkable replication strategy

Keywords: Hepatitis B virus; Chronic hepatitis B; Hepadnaviridae; Vertical transmission; Viral life cycle; p22cr; 22-kDa core-related protein; anti-HBc; anti hepatitis B core protein antibodies; Alix; apoptosis linked gene II interacting protein X; ARD; arginine-ri

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection

Keywords: CAM; ER Stress Response; Assembly Inhibitor Core Protein; Replication; DAA; ALT; alanine aminotransferase; CAM; capsid assembly modulator; cccDNA; covalently closed circular DNA; ER; endoplasmatic reticulum; ETV; entecavir; h-Alb; human albumin; HAP; hete

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Deep sequencing identifies hepatitis B virus core protein signatures in chronic hepatitis B patients

Keywords: Hepatitis B virus core protein; Chronic hepatitis B; Deep sequencing; HBeAg status; Treatment response; HBV; hepatitis B virus; CHB; chronic hepatitis B; NUC; nucleos(t)ide analogues; peg-IFN; pegylated interferon; HBsAg; hepatitis B surface antigen; HBc;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3

Keywords: Antiviral; Immune Response; Immune Therapy; LTB; 3-D; 3-dimensional; AE-T; activated T; APOBEC3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3; CAR; chimeric antigen receptor; cccDNA; covalently closed circular DNA; E:T; effector cell-to

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

INASL Position Statements on Prevention, Diagnosis and Management of Hepatitis B Virus Infection in India: The Andaman Statements

Keywords: AASLD; American Association for the Study of Liver Diseases; ADV; adefovir dipivoxil; ALT; alanine aminotransferase; Anti-HBe; antibodies to hepatitis B envelope antigen; anti-HBs; antibody to hepatitis B surface antigen; APASL; Asian Pacific Association

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2018 سفارش ترجمه

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon

Keywords: Coinfection; Interferon-stimulated Gene; PRR; RIG-I; APOBEC; apolipoprotein B mRNA editing enzyme catalytic subunit; cccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; circDNA; circular DNA; GFP-IRF3; green fluorescent protein-interferon

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

Humanized chimeric mouse models of hepatitis B virus infection

Keywords: HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; SCID; severe combined immunodeficiency; alb-uPA; albumin-promoted urokinase-type plasminogen activator; RAG2; recombinant activation gene 2; RI; repopulation index; FAH; fumarylacetoacetate h

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector

Keywords: Hepatitis B virus; cccDNA; Adeno-associated virus; Immune-competent mouse; Immune-therapeutics; AAV; adeno-associated virus; cccDNA; covalently closed circular DNA; DIG; digoxigenin; dsl; double stranded linear DNA; HBV; Hepatitis B Virus; HDV; Hepatitis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Animal models of HBV infection

Keywords: Animal models; HBV-related viruses; Hepadnaviruses; Humanized mice; Antiviral therapy; Immunopathogenesis; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; pgRNA; pregenomic RNA; DHBV; duck hepatitis B virus; WHV; woodchuck hepatitis virus;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Complete genome sequencing and clinical analysis of intrahepatic hepatitis B virus cccDNA from HCC

Keywords: Hepatitis B virus; cccDNA; Mutation; Survival; Hepatocellular carcinoma;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Impact of hepatitis B vaccination on HBsAg kinetics, interferon-inducible protein 10 level and recurrence of viremia

Keywords: CccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; ECLIA; Electrochemiluminescence immunoassay; ELISA; Enzyme-linked immunosorbent assay; HBsAg; HBV surface antigen; HCC; hepatocellular carcinoma; HOMA-IR; Homeostatic model assessment for i

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Role of hepatitis B core protein in HBV transcription and recruitment of histone acetyltransferases to cccDNA minichromosome

Keywords: Hepatitis B virus; Hepatitis B core protein; HBV transcription; Histone acetylation; Covalently closed circular DNA; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; HBc; hepatitis B core protein; CTD; C-terminal domain; pgRNA; pregenomic R

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Viral minority variants in the core promoter and precore region identified by deep sequencing are associated with response to peginterferon and adefovir in HBeAg negative chronic hepatitis B patients

Keywords: Peginterferon alfa-2a; Adefovir; Ultra-deep pyrosequencing; Mutation; Hepatitis B e antigen; Response marker; 454 DS; 454 deep sequencing; ALT; alanine aminotransferase; BCP; basal core promoter; cccDNA; covalently closed circular DNA; CHB; chronic hepati

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B

Keywords: HBV; Intrahepatic innate immune response; cccDNA; HBsAg;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Host factor PRPF31 is involved in cccDNA production in HBV-replicating cells

Keywords: HBV; cccDNA; PRPF31;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication

Keywords: Hepatitis B Virus Infection; STAT3 Signaling; Hepatocellular Carcinoma; Apoptosis; APR; acute phase response; cDNA; complementary DNA; cccDNA; covalently closed circular DNA; cRNA; complementary RNA; CRP; C-reactive protein; DMSO; dimethyl sulfoxide; FCS;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector

Keywords: Sulfamoylbenzamide; Antiviral agent; HBV; Capsid assembly effector; cccDNA; HBeAg;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Treatment of hepatitis B virus with combination therapy now and in the future

Keywords: Combination therapy; Hepatitis B; Immunotherapy; Immunomodulators; Direct acting antivirals (DAA); Antiviral therapy; cccDNA;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Altered expression of interferon-stimulated genes is strongly associated with therapeutic outcomes in hepatitis B virus infection

Keywords: Chronic hepatitis B; Antiviral therapy; IFN signaling pathway; STAT1; MX; Peg-IFN; pegylated interferon; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; NAs; nucleot(s)ide analogues; CHB; chronic hepatitis B; ETV; entecavir; ISGs; interf

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Interplay between SIRT1 and hepatitis B virus X protein in the activation of viral transcription

Keywords: Hepatitis B virus; Sirtuin; HBx; cccDNA; SIRT1;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver

Keywords: NK Cell; CXCL10; Mouse Model; IL10; HBe; cccDNA; covalently closed circular DNA; CHB; chronically HBV infected; ELISA; enzyme-Linked Immunosorbent Assay; ETV; entecavir; hAlb; human Albumin; HBcAg; hepatitis B core antigen; HBe; hepatitis B envelope; HBs;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Exploring the potential of genome editing CRISPR-Cas9 technology

Keywords: Cas; CRISPR-associated proteins; cccDNA; covalently closed circular DNA; CCR5; C-C chemokine receptor type 5; CHO; Chinese hamster ovary; CRISPRs; clustered regularly interspaced short palindromic repeats; CRISPRa; CRISPR activation; CRISPRi; CRISPR inter

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2017 سفارش ترجمه

Two-way molecular ligation for efficient conversion of monomeric hepatitis B virus DNA constructs into tandem dimers

Keywords: cccDNA; covalently closed circular DNA; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; pg RNA; pregenomic RNA; Hepatitis B virus; Covalently closed circular DNA; Tandem dimer; Prege

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Improved antiviral efficacy using TALEN-mediated homology directed recombination to introduce artificial primary miRNAs into DNA of hepatitis B virus

Keywords: HBV; TALEN; Artificial primary miRNA; cccDNA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Variability in long-term hepatitis B virus dynamics under antiviral therapy

Keywords: CccDNA; Pegylated interferon alpha; Adefovir dipivoxil; Viral dynamics; Mathematical modelling

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

CRISPR/Cas9 produces anti-hepatitis B virus effect in hepatoma cells and transgenic mouse

Keywords: CRISPR/Cas9; HBV; cccDNA; Hydrodynamics;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1

Keywords: SAMHD1; HBV restriction; dNTPase; cccDNA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleIn vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides

Keywords: HBV; hepatitis B virus; ASO; antisense oligonucleotide; HBsAg; hepatitis B surface antigen; HCC; hepatocellular carcinoma; NTCP; sodium taurocholate cotransporting polypeptide; cccDNA; circular covalently closed DNA; RT; reverse transcriptase; HBcAg; hepa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleHBcrAg predicts hepatocellular carcinoma development: An analysis using time-dependent receiver operating characteristics

Keywords: CHB; chronic hepatitis B; HCC; hepatocellular carcinoma; HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus; HBeAg; hepatitis B e antigen; BCP; basal core promoter; HBcrAg; hepatitis B virus core-related antigen; cccDNA; covalently closed circular

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleTreatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study

Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; BSA; bovine serum albumin; blq; below limit of quantification; cccDNA; covalently closed circular deoxyribonucleic acid; CHB; chronic hepatitis B; CHD; chronic hepatitis D; d; hepatocyte deat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleNovel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection

Keywords: HBV; hepatitis B virus; ETV; entecavir; MEND; pH-sensitive multifunctional envelope-type nanodevice; cccDNA; covalently closed circular DNA; HBsAg; hepatitis B virus surface antigen; HBeAg; hepatitis B virus e antigen; HBcAg; hepatitis B virus core antige

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Decay of ccc-DNA marks persistence of intrahepatic viral DNA synthesis under tenofovir in HIV-HBV co-infected patients

Keywords: HBV; hepatitis B virus; cccDNA; covalently-closed circular DNA; IH-DNA; intrahepatic DNA; HIV; human immunodeficiency virus; HBeAg; hepatitis B “e” antigen; IQR; interquartile range; TDF; tenofovir; HCC; hepatocellular carcinoma; NA; nucleoside/nucleo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

EpCAM-regulated intramembrane proteolysis induces a cancer stem cell-like gene signature in hepatitis B virus-infected hepatocytes

Keywords: cccDNA; circular covalently closed DNA; EpCAM; epithelial cell adhesion molecule; EpICD; EpCAM intracellular domain; hCSCs; hepatic cancer stem cells; HBV; hepatitis B virus; HBc; hepatitis B virus core antigen; HCC; hepatocellular carcinoma; PRC2; polyco

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Original ResearchFull Report: Basic and Translational-LiverInterferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis

Keywords: Apolipoprotein B mRNA Editing Enzyme; HBV Persistence; T-Cell Receptor; Immune Regulation; 3D-PCR; differential DNA denaturation PCR; A3; APOBEC3; ALT; alanine aminotransferase; AP; apurinic/apyrimidinic; cccDNA; covalently closed circular DNA; Cp; crossi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Establishment of an inducible HBV stable cell line that expresses cccDNA-dependent epitope-tagged HBeAg for screening of cccDNA modulators

Keywords: Hepatitis B virus; cccDNA; HBeAg; High throughput screening;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Toward Elimination of Hepatitis B Virus Using Novel Drugs, Approaches, and Combined Modalities

Keywords: HBV cure; siRNA; CRISPR/Cas9; Anti-HBV agents; cccDNA; HBsAg; Antiviral therapy;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Suppression of hepatitis B virus antigen production and replication by wild-type HBV dependently replicating HBV shRNA vectors in vitro and in vivo

Keywords: Hepatitis B virus; HBV vector; RNAi; Chronic hepatitis B; HBV transgenic mice; shRNA delivery; HBV; hepatitis B virus; cccDNA; covalently closed circular DNA; CMV-IE; cytomegalovirus immediate early; dsL; double-stranded linear; FACS; fluorescence-activat

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatitis B virus (HBV) X protein-mediated regulation of hepatocyte metabolic pathways affects viral replication

Keywords: HBV; Hepatitis B virus; HCC; Hepatocellular carcinoma; HBx; HBV X protein; cccDNA; Covalently closed circular DNA; ORF; Open reading frame; mTORC1; Mammalian target of rapamycin (mTOR) complex 1; TSC2; Tuberous-sclerosis complex-2; AMPK; AMP-activated pro

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه