دانلود مقالات ISI درباره Cdk1 + ترجمه فارسی

Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration

Keywords: ERK1/2; extracellular signal-regulated kinases 1/2; RSK1/2; p90 ribosomal S6 kinases 1/2; MAPK; mitogen-activated protein kinases; CDK1; cyclin-dependent kinase 1; WWC; WW and C2 domain containing proteins; KIBRA; ERK1/2; RSK1/2; Phosphorylation; Prolifer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer

Keywords: PTTG; pituitary-tumor transforming gene; CDKs; cyclin-dependent protein kinases; CDK1; cyclin dependent kinase 1; FBS; fetal bovine serum; MTT; 3-(4,5-dimethyl-thiazol-2-yl) 2,5-diphenyl tetrazolium bromide; PBS; phosphate-buffered saline; PI; propidium i

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo

Keywords: chk2; check point kinase 2; CDK1; cyclin-dependent kinase 1; ROS; reactive oxygen species; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; DMSO; dimethyl sulfoxide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; P

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

CDC6 controls dynamics of the first embryonic M-phase entry and progression via CDK1 inhibition

Keywords: CDC6; CDK1; Cell-free extract; Embryo; M-phase entry; Xenopus laevis; Mouse zygote; NCTD;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Phosphorylation of p300 increases its protein degradation to enhance the lung cancer progression

Keywords: p300; Phosphorylation; Protein stability; CDK1; Mitosis; Metastasis;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles

Keywords: Cdk1; Cyclin dependent kinase 1; APC/C; Anaphase Promoting Complex/Cyclosome; Emi2; Early mitotic inhibitor 2; XErp1; Xenopus Emi1 related protein 1; PP2A; protein phosphatase 2; MBT; midblastula transition; Embryonic cell cycle; Oscillation; Mathematical

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Differential anti-tumor activities of curcumin against Ras- and Src-activated human adenocarcinoma cells

Keywords: 4E-BP1; eukaryotic initiation factor 4-binding protein 1; Cdk1; cyclin-dependent kinase 1; EGFR; epidermal growth factor receptor; FACS; fluorescence activated cell sorting; IC50; 50% inhibitory concentration; MAPK; mitogen-activated protein kinase; mTOR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

A western blot assay to measure cyclin dependent kinase activity in cells or in vitro without the use of radioisotopes

Keywords: Cdk1; cyclin dependent kinase 1; Cdk2; cyclin dependent kinase 2; CPT; camptothecin; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; EGTA; ethyleneglycol-bis (beta-aminoethylether)- N,N′-tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Oncogenic Ras suppresses Cdk1 in a complex manner during the incubation of activated Xenopus egg extracts

Keywords: Signal transduction; Oncogenic Ras; Cdk1; Cell cycle arrest; Xenopus egg extracts;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Mitotic phosphorylation of MPP8 by cyclin-dependent kinases regulates chromatin dissociation

Keywords: MPP8; Cyclin B1; Cdk1; Chromatin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Evidence for reciliation of RPE1 cells in late G1 phase, and ciliary localisation of cyclin B1

Keywords: Primary cilia; Cyclin B1; CDK1; Aurora A; DNA replication; Cilium disassemblyAurA, Aurora kinase A; BrdU, bromodeoxyuridine; CDK, cyclin-dependent kinase; DAPI, 4’,6-diamidino-2-phenylindole; FBS, fetal bovine serum; HU, hydroxyurea; Mim, mimosine; siRNA,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

STOX1A induces phosphorylation of tau proteins at epitopes hyperphosphorylated in Alzheimer's disease

Keywords: Alzheimer's disease; MAPT; HTAU40; STOX1A; CDK1; Cell cycle;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Inactivation of PI3K/Akt signaling mediates proliferation inhibition and G2/M phase arrest induced by andrographolide in human glioblastoma cells

Keywords: Andrographolide; Glioblastoma; G2/M arrest; Cdk1; PI3K/Akt signaling

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Computational investigation of pathogenic nsSNPs in CEP63 protein

Keywords: CEP63; Centrosomal protein of 63 kDa; nsSNPs; Non-synonymous single nucleotide polymorphisms; CDK1; Cyclin-dependent kinase 1; MDS; Molecular dynamics simulation; RMSD; Root-mean-square deviation; Rg; Radius of gyration; SASA; Solvent-accessible surface

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Role of Mos/MEK/ERK cascade and Cdk1 in Ca2+ oscillations in fertilized ascidian eggs

Keywords: [Ca2+]i oscillations; ERK; Cdk1; Ascidian egg; Fertilization; Phallusia nigra

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

5-epi-Sinuleptolide induces cell cycle arrest and apoptosis through tumor necrosis factor/mitochondria-mediated caspase signaling pathway in human skin cancer cells

Keywords: 5ES; 5-epi-sinuleptolide; 5-Fu; 5-fluorouracil; Apaf-1; apoptotic protease activating factor-1; BCC; basal cell carcinoma; CDK1; cyclin-dependent kinase 1; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethyl sulfoxide; FADD; Fas-associated death domain

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

In vitro growth inhibition of human cancer cells by novel honokiol analogs

Keywords: Honokiol analogs; Cell proliferation; CDK1; Cyclin B1; Human cancer cell

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines

Keywords: Protopine; Microtubules; Mitotic arrest; Cdk1; Apoptosis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Proteomics reveals a switch in CDK1-associated proteins upon M-phase exit during the Xenopus laevis oocyte to embryo transition

Keywords: CDK1; Cyclin B; MPF; M-phase exit; Oocyte activation; Oocyte maturation; Oocyte-to-embryo; Transition;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Towards understanding cell cycle control in Cryptococcus neoformans: Structure–function relationship of G1 and G1/S cyclins homologue CnCln1

Keywords: C. neoformans; S. Cerevisiae; Cyclin; Cdk1; In silico simulations

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Cdk1 and BRCA1 target γ-tubulin to microtubule domains

Keywords: Cdk1; BRCA1; γ-Tubulin; Microtubule; DNA damage response;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The cdk1-cyclin B complex is involved in everolimus triggered resistance in the PC3 prostate cancer cell line

Keywords: Prostate cancer; Everolimus resistance; Tumor growth; Cdk1; Cyclin B

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Sporophytic and gametophytic functions of the cell cycle-associated Mob1 gene in Arabidopsis thaliana L.

Keywords: BSA; Bovine Serum Albumin; Cdc14p; Cell division cycle protein 14; CDK1; Cyclin dependent kinase 1; cDNA; DNA complementary to RNA; DAPI; 4',6-diamidino-2-phenylindole; Dbf2; Dumbbell former; DIC; Differential interference contrast microscopy; DMSO; Dimet

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Evidence that phosphorylation by the mitotic kinase Cdk1 promotes ICER monoubiquitination and nuclear delocalization

Keywords: ICER; Cdk1; Phosphorylation; Ubiquitination

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Mitotic phosphorylation of Aki1 at Ser208 by cyclin B1–Cdk1 complex

Keywords: Aki1; Cdk1; Cyclin B1; Phosphorylation; Mitosis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells

Keywords: CPT, camptothecin; CDDP, cisplatin; Cdk1, cyclin-dependent kinase 1; Chk1, checkpoint kinase 1Cytotoxic drug; Cyclin-dependent kinases; Cdk1; DNA damage response; Checkpoint kinase 1; Histone γ-H2AX; Checkpoint adaptation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Actin cytoskeleton dynamics and the cell division cycle

Keywords: APC; adenomatous polyposis coli; CDK1; cyclin-dependent kinase 1; ECM; extra cellular matrix; FAK; focal adhesion kinase; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; MLCK; myosin light chain kinase; PAK; p21-activate kinase; P

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Discovery of novel CDK1 inhibitors by combining pharmacophore modeling, QSAR analysis and in silico screening followed by in vitro bioassay

Keywords: CDK1; Cancer; Pharmacophore modeling; QSAR; Genetic algorithm; MLR; In silico screening

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Cyclin C and cyclin dependent kinases 1, 2 and 3 in thrombin-induced neuronal cell cycle progression and apoptosis

Keywords: Cyclin C; Cell cycle; Neuronal apoptosis; cdk1; cdk2; cdk3; Thrombin; S phase

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Distinct properties of cyclin-dependent kinase complexes containing cyclin A1 and cyclin A2

Keywords: Cyclin A1; Cyclin A2; CDK1; CDK2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Apigenin causes G2/M arrest associated with the modulation of p21Cip1 and Cdc2 and activates p53-dependent apoptosis pathway in human breast cancer SK-BR-3 cells

Keywords: Apigenin; Apoptosis; CDK1; G2/M phase; p53; SK-BR-3 cells

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

2-(1-Hydroxethyl)-4,8-dihydrobenzo[1,2-b:5,4-b′]dithiophene-4,8-dione (BTP-11) enhances the ATRA-induced differentiation in human leukemia HL-60 cells

Keywords: ATRA; CDK1; C/EBPɛ; Cyclin D; Differentiation; G0/G1 phase arrest; HL-60; 2-(1-Hydroxethyl)-4,8-dihydrobenzo[1,2-b:5,4-b′]dithiophene-4,8-dione (BTP-11)

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Simple, realistic models of complex biological processes: Positive feedback and bistability in a cell fate switch and a cell cycle oscillator

Keywords: Systems biology; Oocyte maturation; Embryonic cell cycle; CDK1; Cyclin; MAP kinase; Xenopus

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology

Keywords: PP1; type 1 protein phosphatase; Ca; Calcium; PP1c; type 1 protein phosphatase catalytic subunit; I-1; inhibitor-1; I-2; inhibitor-2; SR; sarcoplasmic reticulum; LTCC; L-type Ca channel; RyR; ryanodine receptor; SERCA2a; SR/ER-Ca ATPase 2a; PLN; phosphola

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs

Keywords: Egg; Fertilization; Meiosis; Oocyte maturation; CDK1; Securin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

CDC25A phosphatase controls meiosis I progression in mouse oocytes

Keywords: Resumption of meiosis; Meiotic maturation; Mouse oocytes; CDC25A; CDC25B; CDK1; MAPK; Spindle formation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and biological study of 2-amino-4-aryl-5-chloropyrimidine analogues as inhibitors of VEGFR-2 and cyclin dependent kinase 1 (CDK1)

Keywords: CDK1; VEGFR-2; 2-Amino-4-aryl-5-chloropyrimidine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Modulation of CYP1A1 and CYP2B1 expression upon cell cycle progression in cultures of primary rat hepatocytes

Keywords: C/EBP; CCAAT/enhancer binding protein; CDK1; cyclin-dependent kinase 1; CYP; cytochrome P450; BSA; bovine serum albumin; DSM; differentiation stimulating medium; EGF; epidermal growth factor; EROD; 7-ethoxyresorufin-O-deethylase; FBS; fetal bovine serum;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Cell death in leukemia: Passenger protein regulation by topoisomerase inhibitors

Keywords: Leukemia; Mitotic catastrophe; Apoptosis; Aurora B; Survivin; Cdk1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways

Keywords: Quinolone; Mitotic arrest; Cdk1; Bcl-2 family of proteins; Caspase; AIF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Proteomic co-expression of cyclin-dependent kinases 1 and 4 in human cancer cells

Keywords: Cyclin-dependent kinase; Cdk1; Cdk4; Western blotting; Cell lines; Human; Cancer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Regulation of RUNX1/AML1 during the G2/M transition

Keywords: RUNX1/AML1; Phosphorylation; Cell cycle; CDK1; Degradation; Cdc20

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis of 2-amino-4-(7-azaindol-3-yl)pyrimidines as cyclin dependent kinase 1 (CDK1) inhibitors

Keywords: CDK1; 2-Amino-4-(7-azaindol-3-yl)pyrimidine;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure

Keywords: CDK inhibitor; CDK1; CDK2; CDK4; CDK6; X-ray; CDK4 mimic CDK4; E2F

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

The MPAC domain is a novel mitotically regulated domain, removed by apoptotic protease cleavage during cell death

Keywords: Ufd2a; Phosphorylation; Granzyme B; Ubiquitin; Cdk1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

The flavonoid Casticin has multiple mechanisms of tumor cytotoxicity action

Keywords: Flavonoids; p53; p21; Cell cycle; Cyclins; Cdk1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Methionine-stress: A pleiotropic approach in enhancing the efficacy of chemotherapy

Keywords: Methionine-stress; Methioninase; Methionine; Homocysteine; Brain tumors; Cell cycle check points; Mitosis; Temozolomide; Carmustine; p21; p53; p27; CDK1

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Translational control during mitosis

Keywords: Translation; Mitosis; CDK1; Cyclin B complex;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Functional interaction of Purα with the Cdk2 moiety of cyclin A/Cdk2

Keywords: Cell cycle; Origin of DNA replication; Cdk1; Cdk4; Cyclin D1; Cyclin B1; Cyclin E1; Cyclin H; p21; Purα; Purγ; Chromatin immunoprecipitation; c-MYC gene;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Germinal vesicle materials are requisite for male pronucleus formation but not for change in the activities of CDK1 and MAP kinase during maturation and fertilization of pig oocytes

Keywords: CDK1; Germinal vesicle; Male pronucleus; MAP kinase; Sperm head decondensation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه