دانلود مقالات ISI درباره Cdk + ترجمه فارسی

Genetic characterization of highly pathogenic H5 influenza viruses from poultry in Taiwan, 2015

Keywords: KU1; Crane/Kagoshima/KU1/2014; KU13; Crane/Kagoshima/KU13/2014; HA; hemagglutinin; NA; neuraminidase; Tonghai/5; A/chicken/Tonghai/5/2014 (H5N1); GD01; A/duck/Guangdong/GD01/2014 (H5N6); Buan2; A/duck/Korea/Buan2/2014 (H5N8); Gochang1; A/duck/Korea/Gochan

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability

Keywords: In silico prediction; Dermal absorption; Modelling; Bioavailability; Risk assessment; Cosmetic ingredient; Physicochemical properties; Safety evaluation; A; daily amount of product exposed to per kg body weight; CDK; Chemistry Development Kit; DA; dermal

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Endocrine therapy for hormone treatment-naïve advanced breast cancer

Keywords: Advanced breast cancer; Metastatic breast cancer; Endocrine therapy; Endocrine therapy-naïve; CBR; clinical benefit rate; CDK; cyclin-dependent kinase; CI; confidence interval; ER; estrogen receptor; HER; human epidermal growth factor receptor; HR; hazar

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

c-Rel in Epidermal Homeostasis: A Spotlight on c-Rel in Cell Cycle Regulation

Keywords: CDK; cyclin-dependent kinase; IKK; inhibitor of κB kinase; MCC; mitotic checkpoint complex; SAC; spindle assembly checkpoint; TNF; tumor necrosis factor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

d-3-Deoxy-dioctanoylphosphatidylinositol induces cytotoxicity in human MCF-7 breast cancer cells via a mechanism that involves downregulation of the D-type cyclin-retinoblastoma pathway

Keywords: BrdU; 5-bromo-2′-deoxyuridine; CDK; cyclin-dependent kinase; CMC; critical micelle concentration; d-3-deoxy-diC8PI; d-3-deoxy-dioctanoylphosphatidylinositol; l-3,5-dideoxy-diC8PI; l-3,5-dideoxy-dioctanoylphosphatidylinositol; d-diC8PIP3; d-dioctanoyl-ph

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Down-regulation of BNIP3 by olomoucine, a CDK inhibitor, reduces LPS- and NO-induced cell death in BV2 microglial cells

Keywords: Aβ; amyloid β; BH3; Bcl−2 homology domain 3; BNIP3; Bcl-2/adenovirus E1B 19−kDa-interacting protein 3; CNS; central nervous system; cPTIO; carboxy-PTIO; CDK; cyclin-dependent kinase; DMEM; Dulbecco's modified Eagle medium; HD; Huntington's disea

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Retinoid N-(1H-benzo[d]imidazol-2-yl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide induces p21-dependent senescence in breast cancer cells

Keywords: ATRA; all-trans-retinoic acid; CDK; cyclin-dependent kinase; ER; estrogen receptor; RA; retinoic acid; OIS; oncogene-induced senescence; PICS; PTEN-loss induced cellular senescence; SRB; Sulforhodamine B; SABG; senescence-associated β-galactosidase; siRN

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Curcumin-cyclodextrin complexes enhanced the anti-cancer effects of curcumin

Keywords: CD; β-cyclodextrin; CD15; curcumin-cyclodextrin complexes; CDK; cyclin-dependent kinase; CUR; curcumin; FACS; fluorescence activated cell sorter; FTIR; Fourier transform infrared; IC50; 50% inhibitory concentration; MTT; 3-(4,5-Dimethyl-thiagol-2yl)- 2,5

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Original articleMultiple primary melanomas (MPMs) and criteria for genetic assessment: MultiMEL, a multicenter study of the Italian Melanoma Intergroup

Keywords: cyclin-dependent kinase; cyclin-dependent kinase inhibitor 2A; family history; genetic assessment; melanoma; microphthalmia-associated transcription factor; mutation; pancreatic cancer; CDK; cyclin-dependent kinase; CDKN2A; cyclin-dependent kinase inhibit

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

GSK-3 inhibition overcomes chemoresistance in human breast cancer

Keywords: Breast cancer; GSK-3; Chemoresistance; 9-ING-41; Drug development; ADMET; absorption, distribution, metabolism, excretion, toxicity; PK; pharmacokinetic; CDK; cyclin-dependent kinase; PKA; protein kinase A; Akt; protein kinase B; PKC; protein kinase C; GL

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer

Keywords: Epigenetic inhibitors; Prostate cancer; Kidney cells; Nephrotoxicity; 5-Aza; 5-aza-2ʹ-deoxycytidine; CBZ; carbamazapine; CDK; cyclin-dependent kinase; CDKN1a; cyclin-dependent kinase inhibitor 1a; CFZ; carfilzomib; ChIP; chromatin immunoprecipitation; DM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line

Keywords: α3 nAChR; alpha 3 nicotinic Acetylcholine Receptor; ATRA; all-trans Retinoic Acid; BMP-2; Bone morphogenetic protein-2; CCHS; Congenital Central Hypoventilation Syndrome; Cdk; cyclin-dependent kinase; ChIP; chromatin immunoprecipitation; CKI; Cdk inhibit

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleLoss of Gsα impairs liver regeneration through a defect in the crosstalk between cAMP and growth factor signaling

Keywords: cAMP; cyclic adenosine monophosphate; CCl4; carbon tetrachloride; CDK; cyclin-dependent kinase; CREB; cAMP-responsive element-binding protein; Erk; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; Gsα; the stimulatory G protein α

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleMelanocytes/MelanomaThe Long Noncoding RNA SPRIGHTLY Regulates Cell Proliferation in Primary Human Melanocytes

Keywords: CDK; cyclin-dependent kinase; DPPIV; dipeptidyl peptidase-IV; ERK; extracellular signal-regulated kinase; lncRNA; long noncoding RNA; MAPK; mitogen-activated protein kinase; MCM; minichromosome maintenance; siRNA; small interfering RNA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human Melanoma

Keywords: cdk; cyclin-dependent kinase; SA-β-Gal; senescence-associated beta-galactosidase; SAHF; senescence-associated heterochromatin foci; shNS; nonspecific shRNA; shRNA; short hairpin RNA; SIRTs; sirtuins; TMAs; tissue microarrays;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma

Keywords: BRCA1/2; BRCA1 or BRCA2; CDK; cyclin-dependent kinase; FBS; heat-inactivated fetal bovine serum; HGSOC; high-grade serous ovarian carcinoma; HR; homologous recombination; IP; intraperitoneal; pADPr; poly(ADP-ribose) polymer; PARP; poly(ADP-ribose) polymer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms

Keywords: ACN; acetonitrile; CDK; cyclin-dependent kinase; CLK; cdc2-like kinase; CK; casein kinase; DIPEA; diisopropylethylamine; DMEM; Dulbecco's modified Eagle's medium; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; DYRK1A; dual specificity tyrosine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells

Keywords: Panacis Japonici Rhizoma; Chikusetsusaponin IVa methyl ester; Ovarian cancer; Cell cycle arrest; Apoptosis; Metastasis; Bcl-2; B-cell lymphoma 2; CC; column chromatography; CDK; cyclin-dependent kinase; DMEM; Dulbecco's modified Eagle's medium; DMSO; dime

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

p21CIP1/WAF1-dependent inhibition of cardiac hypertrophy in response to Angiotensin II involves Akt/Myc and pRb signaling

Keywords: p21; Cdkn1a; p27; Cdkn1b; Myc; Retinoblastoma; Cyclin D2; Cdk; Cell cycle; Cardiac hypertrophy; Heart failure; Cardiac fibrosis; Angiotensin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Structural Conservation and E2F Binding Specificity within the Retinoblastoma Pocket Protein Family

Keywords: Rb; retinoblastoma; Cdk; Cyclin-dependent kinase; E2FTD; E2F transactivation domain; p107/p130; p107 or p130; RbN; Rb containing a structured N-terminal domain; RbC; Rb containing an intrinsically disordered C-terminal domain; RbPL; Rb containing a ~ 60

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions

Keywords: CDK; cyclic-dependent kinases; DCFH; 2′,7′-dichlorofluorescein diacetate; DMEM; Dulbecco's Modified Eagle Medium; DTT; dithiothreitol; E; etoposide; EB; ethidium bromide; FACS; fluorescence-activated cell sorting; FCS; fetal calf serum; FITC; fluore

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Regulations on growth and development in tomato cotyledon, flower and fruit via destruction of miR396 with short tandem target mimic

Keywords: AOI; area of interest; BK; breaker; CDK; cyclin-dependent kinase; DPA; days post-anthesis; DPS; days post-sowing; GRF; growth-regulating factor; MC; MACROCALYX; MG; mature green; miRNA; microRNA; MT; Micro-Tom; NCBI; National Center for Biotechnology Info

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Long non-coding RNA UCA1 promotes cisplatin/gemcitabine resistance through CREB modulating miR-196a-5p in bladder cancer cells

Keywords: UCA1; CREB; miR-196a-5p; Drug resistance; Bladder cancer; CDK; cyclin-dependent kinase; CREB; cAMP response element-binding protein; DAB; diaminobenzidine; 5-FU; 5-fluorouracil; IHC; immunohistochemistry; lncRNA; long non-coding RNA; miRNA; micro RNA; NC;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

3-Substituted-4-hydroxycoumarin as a new scaffold with potent CDK inhibition and promising anticancer effect: Synthesis, molecular modeling and QSAR studies

Keywords: 4-Hydroxycoumarin; Pyrazolines; 2-Aminopyridine-3-carbonitriles; CDK; Anticancer; Molecular docking; QSARCDK, cyclin dependent kinase; QSAR, quantitative structure activity relationship; AP-1, activator protein-1; RMSE, root mean square error; TLC, thin l

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis

Keywords: Aβ; Amyloid β; AD; Alzheimer's disease; Akt; protein kinase B; AraC; cytosine arabinoside; ATP; adenosine triphosphate; CaM; calmodulin; CaMKIα; Ca2 +/calmodulin-dependent kinase type 1 alpha; CaMKII; Ca2 +/calmodulin-dependent kinase type II; CDK; c

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Role of XPD in cellular functions: To TFIIH and beyond

Keywords: ANT2; an adenine nucleotide translocase that exchanges mitochondrial ATP with cytosolic ADP; CDK; cyclin dependent kinase; CAK; CDK-activating kinase complex; CIA; cytoplasmic FeS assembly; CIA01/2; cytosolic iron-sulfur assembly component ½; CS; Cockayn

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

Oncogenic KRAS signaling and YAP1/β-catenin: Similar cell cycle control in tumor initiation

Keywords: YAP1; Yes; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; eIF4E; eukaryotic translation initiation factor 4E; PI3K; phosphatidylinositide-3-kinase; WNT; Wingless-type mouse mammary tumor virus integration site family m

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival

Keywords: AMPK; 5′ AMP-activated protein kinase; Atg13; autophagy-related protein 13; CDK; cyclin-dependent kinase; DAPI; 4′,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle's medium; DMSO; dimethyl sulfoxide; FDA; US Food and Drug Administration; GF

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics

Keywords: AC; adenylyl cyclase; ACTH; adrenocorticotropic hormone; AKAP; A-kinase anchor protein; AMP; 5′ adenosine monophosphate; AMPK; AMP-activated protein kinase; Arfgap1; ADP-ribosylation factor GTPase-activating protein 1; Arhgef2; Rho guanine nucleotide ex

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Skp1: Implications in cancer and SCF-oriented anti-cancer drug discovery

Keywords: Arf6; ADP-ribosylation factor 6; BIMEL; extra-long isoform of BIM; β-TRCP; β-transducin repeat-containing protein; CDCA3; cell division cycle associated 3; CDK; cyclin-dependent kinase; CENP-E; centrosome-associated protein E; Cks1; cyclin-dependent pro

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Bioluminescent kinase strips: A novel approach to targeted and flexible kinase inhibitor profiling

Keywords: Kinase profiling; Bioluminescence; ADP detection; Selectivity profiles; Kinase assay; Kinase inhibitor; PTM; post-translational modification; FDA; U.S. Food and Drug Administration; BSA; bovine serum albumin; DMSO; dimethyl sulfoxide; TK; tyrosine kinase

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Schizophrenia susceptibility gene product dysbindin-1 regulates the homeostasis of cyclin D1

Keywords: BLOC-1; Biogenesis of lysosome-related organelles complex 1; CDK; Cyclin-dependent kinase; DPC; dystrophin-associated glycoprotein complex; DMEM; Dulbecco's modified Eagle's medium; GFP; Green fluorescent protein; FBS; Fetal bovine serum; MBP; Maltose bin

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy

Keywords: ACUC; Animal Care and Use Committee; AGP; andrographolide; CDK; cyclin dependent kinase; DMSO; dimethyl sulfoxide; DOX; doxorubicin; ERK1/2; extracellular signal-regulated kinases 1/2; FBS; fetal bovine serum; HPLC; high performance liquid chromatography;

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2016 سفارش ترجمه

Gleditsia species: An ethnomedical, phytochemical and pharmacological review

Keywords: AFGS; the ethanol extract from the anomalous fruits of Gleditsia sinensis Lam.; ALI; acute lung injury; AML; acute myelogenous leukemia; AP-1; activator protein-1; ARDS; acute respiratory distress syndrome; bFGF; basic fibroblast growth factor; CDK; cycli

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2016 سفارش ترجمه

Cancer TARGETases: DSB repair as a pharmacological target

Keywords: DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel

دانلود رایگان متن کامل مقاله ISI 110 صفحه سال انتشار : 2016 سفارش ترجمه

KLF10 affects pancreatic function via the SEI-1/p21Cip1 pathway

Keywords: CDK; cyclin dependent kinase; ChIP; chromatin immunoprecipitation; EMSA; electophoretic mobility shift assay; HOMA; homeostasis model assessments; KLF; Krüppel-like factor; OGTT; oral glucose tolerance tests; SEI-1; selected with Ink4a-1 as bait; SERTAD1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathways

Keywords: mTOR; Rapamycin; Rb; TGF-β; eIF4E; 4E-BP1; eIF4E-binding protein-1; CDK; cyclin-dependent kinase; eIF4E; eukaryotic initiation factor 4E; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; S6K; S6 kinase; TGF-β; transforming growth factor-β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Lovastatin suppresses the aberrant tau phosphorylation from FTDP-17 mutation and okadaic acid-induction in rat primary neurons

Keywords: AAV; adeno-associated virus; ACAT; acyl-CoA:cholesterol acyltransferase; AD; Alzheimer's disease; CDK; cyclin-dependent kinase; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; FTDP-17; frontotemporal dementia and Parkinson

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cell Cycle Regulation of Smooth Muscle Cells-Searching for Inhibitors of Neointima Formation: Is Combretastatin A4 an Alternative to Sirolimus and Paclitaxel?

Keywords: CA4; combretastatin A4; CDK; cyclin-dependent kinase; CI; confidence interval; mTOR; mammalian target of rapamycin; PPARγ; peroxisome proliferator activated receptor γ; SMC; smooth muscle cell;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Emerging role of protein phosphatases changes the landscape of phospho-signaling in DNA damage response

Keywords: 53BP1; p53 binding protein 1; ATM; ataxia-telangiectasia mutated; ATR; ataxia telangiectasia and Rad3 related; BLM; blooms syndrome RecQ helicase-like, human homolog of SGS1; BRCA1; breast cancer 1, early onset; CDC; cell division cycle; CDK; cyclin depen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis

Keywords: CHK; CSK (C-terminal Src kinase)-homologous kinase; CLK; Cdc2-like kinase; HIPK; homeodomain-interacting protein kinase; PIM; proviral integration of moloney murine leukemia virus; PKD; protein kinase D; FLT; Fms-like tyrosine kinase; CDK; cyclin-dependen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Vaccination with cyclin-dependent kinase tick antigen confers protection against Ixodes infestation

Keywords: Tick; Vaccine; Ixodes persulcatus; CDK; Cell cycle;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

miR-340 inhibits glioblastoma cell proliferation by suppressing CDK6, cyclin-D1 and cyclin-D2

Keywords: Cell cycle; CDK; Cyclin; Glioblastoma; miR-340;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B

Keywords: Cdc25B; cell division cycle 25B phosphatase; Cdk; cyclin-dependent kinase; IC50; concentration that inhibits enzyme activity by 50% of the maximum activity; OMFP; O-methyl fluorescein phosphate; Cdc25B; 3-Amino-1,2-dihydro-1-isoquinolinone; Palladium cros

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The Bmi-1 helix-turn and ring finger domains are required for Bmi-1 antagonism of (−) epigallocatechin-3-gallate suppression of skin cancer cell survival

Keywords: Bmi-1; B-cell-specific Moloney murine leukemia virus integration site 1; HT; helix-turn; RF; ring finger; Ezh2; enhancer of zeste homolog 2; PcG; polycomb group; H2AK119ub; histone H2A ubiquitinated on lysine 119; H3K27me3; histone H3 trimethylation on

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportSynergistic anti-tumor actions of luteolin and silibinin prevented cell migration and invasion and induced apoptosis in glioblastoma SNB19 cells and glioblastoma stem cells

Keywords: CDK; cyclin-dependent kinase; DMSO; dimethyl sulfoxide; ECL; enhanced chemiluminescence; FBS; fetal bovine serum; GSC; glioblastoma stem cells; ICAD; inhibitor of caspase activated DNase; IgG; immunoglobulin G; iNOS; inducible nitric oxide synthase; LUT;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Discovery and development of Seliciclib. How systems biology approaches can lead to better drug performance

Keywords: Seliciclib; Systems biology; CDK;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Myc and cell cycle control

Keywords: Myc; Cell cycle; Proliferation; Cyclin; Cdk; p21; p27;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

PI3K/Akt signaling in osteosarcoma

Keywords: OS; osteosarcoma; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; IGF1R; insulin-like growth factor 1 receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Antiproliferative activity of the isoindigo 5′-Br in HL-60 cells is mediated by apoptosis, dysregulation of mitochondrial functions and arresting cell cycle at G0/G1 phase

Keywords: Isoindigo; Anticancer; Apoptosis; Mitochondria dysfunction; Cell cycle; CDK; 5′-Br; [(E)-1-(5′-bromo-2′-oxoindolin-3′-ylidene)-6-ethyl-2,3,6,9-tetrahydro-2,9-dioxo-1H-pyrrolo[3,2-f]quinoline-8-carboxylic acid]; ΔΨm; difference in mitochondrial t

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه