Keywords: ترخیص کالا از گمرک; biliary excretion; hepatocytes; clearance; drug transport; hepatobiliary disposition; in vitro/in vivo correlations (IVIVC); organic aniontransporting polypeptide transporters; P-glycoprotein;
مقالات ISI ترخیص کالا از گمرک (ترجمه نشده)
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Keywords: ترخیص کالا از گمرک; Fusion power plant; Recycling; Clearance; Radioactive materials multiple reuse; Waste disposal; Carbon-14
Keywords: ترخیص کالا از گمرک; ball; screw; nut; gearing; clearance; distribution; carrying capacity
Keywords: ترخیص کالا از گمرک; Interlocking Stabilized Earth Block; Compression test; Contact area; Clearance; F.E.M; Cracking pattern
The association of CCL3 and CCL4 polymorphisms with HCV clearance in Chinese Han population
Keywords: ترخیص کالا از گمرک; HCV; hepatitis C virus; SVR; sustained virologic response; pegIFN-α; pegylated interferon-α; RBV; ribavirin; SNPs; single nucleotide polymorphisms; WT; wild-type; GLU; glucose; GWAS; genome-wide association study; MIP-1α; macrophage inflammatory protei
Verification of post-chemotherapeutic clearance of Theileria equi through concordance of nested PCR and immunoblot
Keywords: ترخیص کالا از گمرک; Theileria equi treatment; Piroplasmosis; Clearance; Imidocarb diproprionate;
Utility of in vitro clearance in primary hepatocyte model for prediction of in vivo hepatic clearance of psychopharmacons
Keywords: ترخیص کالا از گمرک; CYP; cytochrome P450; LC-MS/MS; liquid chromatography tandem mass spectrometry; Pharmacokinetic model; Primary hepatocytes; In vitro - in vivo extrapolation; Psychopharmacons; Clearance; Bioavailability;
Safety, immunogenicity, and clinical outcomes in patients with Morquio A syndrome participating in 2 sequential open-label studies of elosulfase alfa enzyme replacement therapy (MOR-002/MOR-100), representing 5â¯years of treatment
Keywords: ترخیص کالا از گمرک; Morquio A; Mucopolysaccharidosis IVA; Long-term extension; Elosulfase alfa; 3MSCT; 3-min stair climb test; 6MWT; 6-min walk test; AE; adverse event; AUC0ât; area under the curve from time 0 to last measurable concentration; AUCinf; area under the curve
Cellular Pharmacokinetic Model-Based Analysis of Genistein, Glyceollin, and MK-571 Effects on 5 (and 6)-Carboxy-2â²,7â²-Dichloroflourescein Disposition in Caco-2 Cells
Keywords: ترخیص کالا از گمرک; active transport; Caco-2 cells; drug transport; efflux pumps; intestinal secretion/transport; membrane transport; pharmacokinetics; transcellular transport; transporters; ABCC2; ATP binding cassette sub-family C, member 2; ABCC3; ATP binding cassette sub-
Effects of sulfur-fumigation on the pharmacokinetics, metabolites and analgesic activity of Radix Paeoniae Alba
Keywords: ترخیص کالا از گمرک; AUC; area under the plasma concentration-time curve; BS; Radix Paeoniae Alba; CID; collision-induced dissociation; CL; clearance; Cmax; maximum plasma concentration; FDA; US Food and Drug Administration; HPLC/UV; high performance liquid chromatography/u
Numerical analysis for impacts of nozzle end-clearances on aerodynamic performance and forced response in a VNT turbine
Keywords: ترخیص کالا از گمرک; Clearance; Forced response; Mode analysis; Performance; Reliability; Variable Nozzle Turbine (VNT);
Suitability of the AUC Ratio as an Indicator of the Pharmacokinetic Advantage in HIPEC
Keywords: ترخیص کالا از گمرک; Clinical pharmacokinetics; Simulations; Cancer chemotherapy; Absorption; Mathematical models; Clearance; HIPEC; hyperthermic intraoperative peritoneal chemotherapy; iv; intravenous; PKA; pharmacokinetic advantage; ka; absorption rate constant; ka_app; app
Kinematic chains isomorphism identification using link connectivity number and entropy neglecting tolerance and clearance
Keywords: ترخیص کالا از گمرک; Clearance; Entropy; Isomorphism; Kinematic chain; Link connectivity number; Tolerance;
Numerical and experimental investigation of fitting tolerance effects on damage and failure of CFRP/Ti double-lap single-bolt joints
Keywords: ترخیص کالا از گمرک; Composite; Bolted joint; Clearance; Interference; Damage;
A comparison of the lung clearance kinetics of solid lipid nanoparticles and liposomes by following the 3H-labelled structural lipids after pulmonary delivery in rats
Keywords: ترخیص کالا از گمرک; Liposome; SLN; Drug delivery; Pulmonary; Clearance; Inhalation; BALF; bronchoalveolar lavage fluid; SEC; size exclusion chromatography; LPS; lipopolysaccharide; DAPI; 4â²,6-diamidino-2-phenylindole;
In vivo bio-distribution, clearance and toxicity assessment of biogenic silver and gold nanoparticles synthesized from Abutilon indicum in Wistar rats
Keywords: ترخیص کالا از گمرک; Biogenic silver and gold nanoparticles; Bio-distribution; Clearance; Biochemical parameters; Histological analysis;
Internal exposure-based pharmacokinetic evaluation of potential for biopersistence of 6:2 fluorotelomer alcohol (FTOH) and its metabolites
Keywords: ترخیص کالا از گمرک; 6:2 fluorotelomer alcohol; Pharmacokinetics; Internal exposure; Clearance; Area under the curve; Allometric scaling; Biopersistence;
Defining level A IVIVC dissolution specifications based on individual in vitro dissolution profiles of a controlled release formulation
Keywords: ترخیص کالا از گمرک; AUC; area under the curve; BE; bioequivalence; CI; confidence interval; CL; clearance; Cmax; maximum plasma concentration; CR; controlled release; CV; coefficient of variation; f2; similarity factor; FTFF; the fastest tablet of the fastest dissolving form
Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport
Keywords: ترخیص کالا از گمرک; AME; absorption-modifying excipient; CLCr; 51Cr-EDTA Clerance; CL; clearance; COX; cyclooxygenase; IEC; intestinal epithelial cells; Jabs; absorptive flux; nAChR; nicotinic acetylcholine receptor; SDS; sodium dodecyl sulfate; SPIP; single-pass intestinal
Discovery and characterization of a potent Wnt and hedgehog signaling pathways dual inhibitor
Keywords: ترخیص کالا از گمرک; Wnt signaling pathway; Hedgehog signaling pathway; Porcupine; Smoothened; Antagonist; Stem cell; Cancer therapy; AUC; area under the plasma time-concentration curve; BCC; basal cell carcinoma; BPO; benzoyl peroxide; CL; clearance; CSC; cancer stem cells;
Evaluating the intestinal and oral absorption of the prodrug valacyclovir in wildtype and huPepT1 transgenic mice
Keywords: ترخیص کالا از گمرک; ACV; Acyclovir; AUC0-180; Area under the plasma concentration-time curve from 0 to 180â¯min; CL; Clearance; Cmax; Maximum plasma concentration; F; Bioavailability; Gly-Sar; glycylsarcosine; huPepT1; Humanized peptide transporter 1; Inu; Inulin; Km; Micha
Ferrocene-based inhibitors of hepatitis C virus replication that target NS5A with low picomolar in vitro antiviral activity
Keywords: ترخیص کالا از گمرک; ABH; 2-azabicyclo[2.2.1]heptanyl; Bpin; (pinacolato)boryl; BZD; benzimidazolyl; CL; clearance; Cp; cyclopentadienyl; Fc; ferrocene or ferrocenyl; FcI2; 1,1â²-diiodoferrocene; FQ; ferroquine; GT; genotype; Im; imidazolyl; Moc; methoxycarbonyl; MRT; mean r
The effects of three absorption-modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs
Keywords: ترخیص کالا از گمرک; AME; absorption-modifying excipient; API; active pharmaceutical ingredient; BCS; biopharmaceutics classification system; BE; bioequivalence; CL; clearance; CPE; critical pharmaceutical excipient; Ffirstpass; firstpass extraction; GI; gastrointestinal; Pap
Individual serum bile acid profiling in rats aids in human risk assessment of drug-induced liver injury due to BSEP inhibition
Keywords: ترخیص کالا از گمرک; ALT; alanine amino transferase; AST; aspartate amino transferase; AUClast; area under the plasma time curve from time 0 to the last measured concentration (24Â h); BSEP; Bile Salt Export Pump; CL; clearance; C0; highest initial plasma concentration of dru
Influence of body size, metabolic rate and life history stage on the uptake and excretion of the lampricide 3-trifluoromethyl-4-nitrophenol (TFM) by invasive sea lampreys (Petromyzon marinus)
Keywords: ترخیص کالا از گمرک; Allometry; Phenols; Piscicide; Sea lamprey control; Clearance; Oxygen consumption; Invasive species; Metabolic rate; Scaling; Kleiber's law;
The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM
Keywords: ترخیص کالا از گمرک; Low-density lipoprotein receptor-related protein 1 (LRP1); ABC transporter B1/P-glycoprotein (ABCB1/P-gp); Phosphatidylinositol-binding clathrin assembly protein (PICALM); Amyloid-beta (Aβ); Blood-brain barrier (BBB); Transcytosis; Alzheimer's disease
Role of efflux transporters in the absorption, distribution and elimination in rodents of a novel PDE4 inhibitor, CHF6001
Keywords: ترخیص کالا از گمرک; ADME; absorption, distribution, metabolism and excretion; AUC0-t(last); area under the concentration-time curve up to the last measurable concentration; AUCinf; area under the concentration-time curve up to infinity; AUCÏ; area under the concentration-ti
Botany, traditional use, phytochemistry, pharmacology, quality control, and authentication of Radix Gentianae Macrophyllae-A traditional medicine: A review
Keywords: ترخیص کالا از گمرک; Qinjiao; Phytochemical; Pharmacology; Pharmacokinetic; Quality control; Authentication; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under curve; 6-BA; 6-benzylaminopurine; CCl4; carbon tetrachloride; Cl; clearance; Cmax; conc
Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives
Keywords: ترخیص کالا از گمرک; PK; pharmacokinetics; CL; clearance; F; bioavailability; AUC; area under the blood concentration time curve; MS; liver microsomal metabolic stability; sc; subcutaneous; qd; quaque die; CNS; central nervous system; bid; bis in die; Androgen receptor; Selec
Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India
Keywords: ترخیص کالا از گمرک; HPV; HIV; Genotypes; Incidence; Clearance; Natural history;
Role of Phosphatidylserine-Derived Negative Surface Charges in the Recognition and Uptake of Intravenously Injected B16BL6-Derived Exosomes by Macrophages
Keywords: ترخیص کالا از گمرک; phospholipids; static charge; lipids; pharmacokinetics; nanoparticles; clearance; physicochemical;
Quantification of EC-18, a synthetic monoacetyldiglyceride (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), in rat and mouse plasma by liquid-chromatography/tandem mass spectrometry
Keywords: ترخیص کالا از گمرک; ACN; acetonitrile; AUC0ââ; area under the curve from time zero to infinity; AUMC0ââ; the area under the first moment curve from time zero to infinity; CL; clearance; Cmax; maximum concentration; FA; formic acid; IPA; isopropyl alcohol; IS; interna
Direct contact thermoelectric generator (DCTEG): A concept for removing the contact resistance between thermoelectric modules and heat source
Keywords: ترخیص کالا از گمرک; Thermoelectric generator (TEG); Direct contact thermoelectric generator (DCTEG); Waste heat recovery; Contact resistance; Efficiency improvement; Clearance;
Supplemental Analysis of the Prediction of Hepatic Clearance of Binary Mixtures of Bisphenol A and Naproxen Determined in an Isolated Perfused Rat Liver Model to Promote the Understanding of Potential Albumin-Facilitated Hepatic Uptake Mechanism
Keywords: ترخیص کالا از گمرک; albumin-mediated uptake; clearance; DDI; drug interaction; hepatocytes; IVIVE; IPRL; pharmacokinetics; PBPK models;
Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics
Keywords: ترخیص کالا از گمرک; AC; aconitine; AUC; area under concentration-time curve; cTnI; cardia troppnin I; CL; clearance; CK; creatine kinase; LD50; 5% half-lethal dose; LD50; half-lethal dose; NSE; neurone specific enolase; P-gp; P-glycoprotein; S100-β; neuron-enriched S100 bet
Quantification of IDP-73152, a novel antibiotic, in plasma from mice, rats and humans using an ultra-high performance liquid chromatography/tandem mass spectrometry method for use in pharmacokinetic studies
Keywords: ترخیص کالا از گمرک; AUC0â24; area under the curve from time zero to 24Â h; AUC0ââ; area under the curve from time zero to infinity; AUMC0ââ; the area under the first moment curve from time zero to infinity; CL; clearance; Cmax; maximum concentration; IS; internal s
Model based population PK-PD analysis of furosemide for BP lowering effect: A comparative study in primary and secondary hypertension
Keywords: ترخیص کالا از گمرک; Furosemide; PK-PD modeling; Blood pressure; Anti-hypertensive; Diuretic; NONMEM; (SHR); Spontaneously hypertensive rats; (DOCA-salt rats); Deoxycorticosterone acetate-salt induced hypertensive rats; (PK-PD); Pharmacokinetic-pharmacodynamic; (NONMEM); Nonl
Research paperBiodistribution of radiolabeled polyglutamic acid and PEG-polyglutamic acid nanocapsules
Keywords: ترخیص کالا از گمرک; AUC; area under the curve; Cl; clearance; CTAB; hexadecyltrimethylammonium bromide; DTPA; diethylenetriamine pentacetic acid; 14:0 DTPA-PE; 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid; % ID; percentage of the tota
Comprehensive assessment of Cucurbitacin E related hepatotoxicity and drug-drug interactions involving CYP3A and P-glycoprotein
Keywords: ترخیص کالا از گمرک; Cucurbitacin E; CYP3A; P-glycoprotein; Hepatotoxicity; Drug-drug interactions; CuE; cucurbitacin E; P-gp; p-glycoprotein; Cmax; the maximum serum concentration; AUC; area under the concentration-time curve; CL; clearance; Vd; volume of distribution; t1/2;
Pharmacokinetics, pharmacodynamics and safety profiling of IS01957, a preclinical candidate possessing dual activity against inflammation and nociception
Keywords: ترخیص کالا از گمرک; Pharmacokinetics; Inflammation; Nociception; Safety pharmacology; IS01957; Para-coumaric acid derivative; p-CA; Para coumaric acid; ADME; Absorption, distribution, metabolism and excretion; CH; Chlorpromazine hydrochloride; PS; Pentobarbital sodium; PBS;
Characterising the effect of antimalarial drugs on the maturation and clearance of murine blood-stage Plasmodium parasites in vivo
Keywords: ترخیص کالا از گمرک; Malaria; Plasmodium berghei; Artemisinin; Mefloquine; Clearance; In vivo; Drug action;
Chaos vibration of pinion and rack steering trapezoidal mechanism containing two clearances
Keywords: ترخیص کالا از گمرک; Pinion and rack steering mechanism; Clearance; Chaos; Stability;
Research paperEffect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers
Keywords: ترخیص کالا از گمرک; PEG; polyethylene glycol; BALF; bronchoalveolar lavage fluid; SEC; size exclusion chromatography; LPS; lipopolysaccharide; PBS; phosphate buffered saline; BSA; bovine serum albumin; Dendrimer; Pulmonary; Drug delivery; Clearance; Inhalation;
Pharmacokinetic and screening studies of the interaction between mononuclear phagocyte system and nanoparticle formulations and colloid forming drugs
Keywords: ترخیص کالا از گمرک; ABC; accelerated blood clearance; ANC; absolute neutrophil count; BLQ; below limit of quantification; CL; clearance; DC; dendritic cells; DHR; dihydrorhodamine; FCM; flow cytometry; fMLP; N-formyl-methionine-leucine-phenylalanine; GLP; Good laboratory Pra
Dual 7-ethyl-10-hydroxycamptothecin conjugated phospholipid prodrug assembled liposomes with in vitro anticancer effects
Keywords: ترخیص کالا از گمرک; SN38; 7-ethyl-10-hydroxycamptothecin; CPT-11; irinotecan; TEM; transmission electron microscopy; cyro-TEM; cryogenic transmission electron microscopy; FDA; Food and Drug Administration; DDS; drug delivery system; EPR; enhanced permeability and retention;
Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters
Keywords: ترخیص کالا از گمرک; Fluorine; Bile acids; Liver transporters; PET imaging; Tritium; Preclinical study; Click chemistry; Clearance;
Studying of Manufacturing Tolerance Influence on the Performance of GTE Rotor Elastic Rings
Keywords: ترخیص کالا از گمرک; Damper; elastic rings; support; flexibility; rigidity; tolerance band; interference; clearance; elastic zone; sliding; separation of elastic ring bulge;
Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential
Keywords: ترخیص کالا از گمرک; ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c
IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds
Keywords: ترخیص کالا از گمرک; API; active pharmaceutical ingredient; AUC; area under the curve; BCS; biopharmaceutics classification system; BP; blood-to-plasma ratio; Cmax; maximum concentration; CL; clearance; Do; dose number according to BCS; DDI; drug-drug interaction; EFPIA; Euro
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes
Keywords: ترخیص کالا از گمرک; AFE; Average Fold Error; AAFE; Absolute Average Fold Error; API; Active pharmaceutical ingredient; AUC; Area under the curve; BCS; Biopharmaceutics classification system; BE; Bioequivalence; BP; Blood-to-plasma ratio; CCC; Concordance Correlation Coeffici