دانلود مقالات ISI درباره ترخیص کالا از گمرک + ترجمه فارسی

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Keywords: ترخیص کالا از گمرک; API; Active pharmaceutical ingredient; AUC; Area under the curve; BCS; Biopharmaceutics classification system; BE; Bioequivalence; BP; Blood-to-plasma ratio; CL; Clearance; CL/F; Apparent clearance; Cmax; Maximum concentration; Do; Dose number; fa; Fracti

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Quantitative Analyses of the Influence of Parameters Governing Rate-Determining Process of Hepatic Elimination of Drugs on the Magnitudes of Drug-Drug Interactions via Hepatic OATPs and CYP3A Using Physiologically Based Pharmacokinetic Models

Keywords: ترخیص کالا از گمرک; cytochrome P450; drug interaction; hepatic clearance; mathematical model; organic anion-transporting polypeptide transporters; pharmacokinetics; AUC; area under the plasma concentration-time curve; CL; clearance; CLint,all; overall hepatic intrinsic cle

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Involvement of organic cation transporter 3 (Oct3/Slc22a3) in the bioavailability and pharmacokinetics of antidiabetic metformin in mice

Keywords: ترخیص کالا از گمرک; Metformin; OCT3; Transporter; Intestinal absorption; Bioavailability; Mouse; AUC; area under the plasma concentration-time curve; CL; clearance; Cmax; maximum concentration; OCT/Oct; organic cation transporter; SLC; solute carrier; tmax; time to maximum

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Genetic variants in the regulatory region of SLC10A1 are not associated with the risk of hepatitis B virus infection and clearance

Keywords: ترخیص کالا از گمرک; Regulatory variants; Hepatitis B virus; Cellular receptor; Susceptibility; Clearance;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

IBI302, a promising candidate for AMD treatment, targeting both the VEGF and complement system with high binding affinity in vitro and effective targeting of the ocular tissue in healthy rhesus monkeys

Keywords: ترخیص کالا از گمرک; VEGF; Complement proteins; Bispecific; Binding affinity; Pharmacokinetics; ACP; alternative complement pathway; AMD; age-related macular degeneration; AUC; areas under the curve; CCK-8; Cell Counting Kit-8; CCP; classical complement pathway; CL; clearance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial

Keywords: ترخیص کالا از گمرک; actinic keratoses; actinic keratosis; blinded; clearance; clobetasol; corticosteroid; cosmesis; cosmetic outcome; cure rate; glucocorticoid; hyperkeratotic; inflammation; ingenol mebutate; local skin responses; pain; patient satisfaction; photodamage; pru

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

A semi-automated method for extracting vertical clearance and cross sections in tunnels using mobile LiDAR data

Keywords: ترخیص کالا از گمرک; LIDAR; Mobile; Inspection; Semi-automation; Clearance; Tunnel;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Numerical evaluation of the clearance geometries effect on the flow field and performance of a hydrofoil

Keywords: ترخیص کالا از گمرک; Hydrofoil; Clearance; Tip leakage vortex; Tip separation vortex; Cavitation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A multicenter, randomized, placebo-controlled trial for cilostazol in patients with mild cognitive impairment: The COMCID study protocol

Keywords: ترخیص کالا از گمرک; Alzheimer's disease; Cilostazol; Clearance; Clinical trial; Drug repositioning;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Potential exposure routes and accumulation kinetics for poly- and perfluorinated alkyl compounds for a freshwater amphipod: Gammarus spp. (Crustacea)

Keywords: ترخیص کالا از گمرک; Perfluorinated compounds; Sediment; Gammarus spp.; Exposure route; Uptake rate; Clearance; BSAF

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Simulation and experimental study on the effect of channeling flows on the transport of toxins in hemodialyzers

Keywords: ترخیص کالا از گمرک; Channeling flow; Mass transport; Hemodialyzer; Hollow fiber membrane; Clearance;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The Role of Extracellular Binding Proteins in the Cellular Uptake of Drugs: Impact on Quantitative In Vitro-to-In Vivo Extrapolations of Toxicity and Efficacy in Physiologically Based Pharmacokinetic-Pharmacodynamic Research

Keywords: ترخیص کالا از گمرک; ADME; clearance; disposition; distribution; hepatocytes; IVIVE; partition coefficients; pharmacokinetics; pharmacodynamics; PKPD;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Tolerability, exposure and pharmacokinetics in healthy subjects of a Chinese herbal medicine MaZiRenWan (MZRW): Study protocol for a randomized open-labelled, three-arm phase 0/1 clinical trial

Keywords: ترخیص کالا از گمرک; MZRW; MaZiRenWan; AUC; the area under the plasma concentration-time curve; Cmax; the peak plasma concentration of an ingredient after administration; tmax; the time to reach Cmax; t1/2; the elimination half-life; CL; clearance; ADME; the absorption, distr

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study

Keywords: ترخیص کالا از گمرک; ACN; acetonitrile; AD; Alzheimer disease; AUCtotal; area under curve/bioavailability; CAS; catalytic anionic site; Cmax; maximal plasma concentration; CL; clearance; FDA; US Food and drug administration; hAChE/AChE; human acetylcholinesterase/acetylcholin

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Malaria and HIV among pediatric inpatients in two Tanzanian referral hospitals: A prospective study

Keywords: ترخیص کالا از گمرک; BMC; Bugando Medical Centre; BS; blood smear; HRP-II; histidine-rich protein-2; IQR; interquartile range; mRDT; rapid diagnostic test; NPV; negative predictive value; OR; odds ratio; PCR; polymerase chain reaction; PITC; provider-initiated testing and cou

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Andrographis paniculata: Dissolution investigation and pharmacokinetic studies of four major active diterpenoids after multiple oral dose administration in healthy Thai volunteers

Keywords: ترخیص کالا از گمرک; 1; andrographolide; 2; 14-deoxy-11, 12-didehydroandrographolide; 3; neoandrographolide; 4; 14-deoxyandrographolide; AUC; area under plasma concentration-time curve; Cmax; maximum concentration; Cl; clearance; EDTA; ethylenediaminetetraacetic acid; F; bioa

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Anal human papillomavirus in HIV-uninfected men who have sex with men: incidence and clearance rates, duration of infection, and risk factors

Keywords: ترخیص کالا از گمرک; Anal infection; Clearance; HIV-negative; Human papillomavirus; Incidence; Markov; Men who have sex with men; Risk factors;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Ingenol mebutate gel for actinic keratosis: The link between quality of life, treatment satisfaction, and clinical outcomes

Keywords: ترخیص کالا از گمرک; actinic keratosis; clearance; ingenol mebutate; quality of life; Skindex-16; Treatment Satisfaction Questionnaire for MedicationAK, actinic keratosis; QoL, quality of life; TSQM, Treatment Satisfaction Questionnaire for Medication

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Studies of Nontarget-Mediated Distribution of Human Full-Length IgG1 Antibody and Its FAb Fragment in Cardiovascular and Metabolic-Related Tissues

Keywords: ترخیص کالا از گمرک; pharmacokinetics; distribution; diffusion; IgG antibody; nontargeted full-length antibody; nontargeted FAb antibody; immunoassay; perfusion; metabolic diseases; clearance; mathematical model;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The Effect of Intravenous Sulfobutylether7-β-Cyclodextrin on the Pharmacokinetics of a Series of Adamantane-Containing Compounds

Keywords: ترخیص کالا از گمرک; cyclodextrins; complexation; pharmacokinetics; distribution; clearance; renal excretion;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular reproductive characteristics of the reef coral Pocillopora damicornis

Keywords: ترخیص کالا از گمرک; Clearance; Coral; Enzyme; Molecular reproduction; Regeneration; Steroid hormones; Steroidogenesis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of the toxicology and pharmacokinetics of recombinant factor VIII Fc fusion protein in animals

Keywords: ترخیص کالا از گمرک; aPTT; activated partial thromboplastin time; AUC∞; area under the curve from zero to time infinity; AUClast; area under the curve up to the last measurable concentration; BW; body weight; CL; clearance; Cmax; maximum plasma concentration; ECG; electroca

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The Induction of Prolonged Myelopoietic Effects in Monkeys by GW003, A Recombinant Human Granulocyte Colony-Stimulating Factor Genetically Fused to Recombinant Human Albumin

Keywords: ترخیص کالا از گمرک; G-CSF; albumin; fusion protein; pharmacokinetics; pharmacodynamics; toxicokinetics; clearance;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Preclinical and first-in-human evaluation of PRX-105, a PEGylated, plant-derived, recombinant human acetylcholinesterase-R

Keywords: ترخیص کالا از گمرک; AChE; acetylcholinesterase; AUC; area under time concentration curve; BuChE; butyrylcholinesterase; CL; clearance; DEPQ; 7-[(diethoxyphosphinyl)oxy]-1-methylquinolinium methyl sulfate; IV; intravenous; kel; elimination rate constant; OP; organophosphorous

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of Repeated Injections of Adenosine Diphosphate-Encapsulated Liposomes Coated with a Fibrinogen γ-Chain Dodecapeptide Developed as a Synthetic Platelet Substitute on Accelerated Blood Clearance in a Healthy and an Anticancer Drug-Induced Thrombocyt

Keywords: ترخیص کالا از گمرک; liposome; adenosine-diphosphate; dodecapeptide; accelerated blood clearance phenomenon; thrombocytopenia; platelet substitute; pegylation; disposition; clearance; pharmacokinetics

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Evaluation of the toxicology, pharmacokinetics, and local tolerance of recombinant factor IX Fc fusion protein in animals

Keywords: ترخیص کالا از گمرک; aPTT; activated partial thromboplastin time; AUClast; area under the time versus plasma concentration curve from the time of dose administration to the last measurable concentration; BW; body weight; CL; clearance; Cmax; maximum plasma concentration; ECG;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

In vivo biodistribution and clearance of peptide amphiphile micelles

Keywords: ترخیص کالا از گمرک; Peptide amphiphile; Micelle; Nanoparticle; Biodistribution; Clearance;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of B1a Cells in Peritoneal Cavity by T Cell-Independent Antigen Expressed on Polymeric Micelle

Keywords: ترخیص کالا از گمرک; polymeric drug carrier; micelle; nanoparticles; clearance; immune response; immunology;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice

Keywords: ترخیص کالا از گمرک; exosome; streptavidin; lactadherin; radioisotope; quantitative analysis; pharmacokinetics; biomaterials; nanoparticles; phospholipids; clearance;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Role of organic cation transporters (OCTs) in the brain

Keywords: ترخیص کالا از گمرک; Organic cation transporter; Monoamines; Clearance; Anxiety; Stress; Antidepressants5-HT, serotonin; D22, decynium22; DA, dopamine; DAT, dopamine transporter; FST, forced-swim test; NE, norepinephrine; NET, norepinephrine transporter; OCT, organic cation t

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

An analysis of HPV infection incidence and clearance by genotype and age in men: The HPV Infection in Men (HIM) Study

Keywords: ترخیص کالا از گمرک; Human papillomavirus; Natural history; Incidence; Clearance; Age-specific; HIM Study

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Preclinical Pharmacokinetics and In Vitro Metabolism of Asunaprevir (BMS-650032), a Potent Hepatitis C Virus NS3 Protease Inhibitor

Keywords: ترخیص کالا از گمرک; ADME; antiinfectives; in vitro/in vivo correlations (IVIVC); disposition; hepatic clearance; clearance; metabolism; P-glycoprotein; pharmacokinetics; bioavailability

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Original ResearchFull Report: Basic and Translational-LiverCSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

Keywords: ترخیص کالا از گمرک; Drug-Induced Liver Damage; Clearance; Immune Response; M-CSF; ALF; acute liver failure; ALT; alanine aminotransferase; Ccr2; chemokine receptor 2; CSF1; colony-stimulating factor 1; CSF1R; colony-stimulating factor 1 receptor; Fc; fragment, crystallizable

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2015 سفارش ترجمه

Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice

Keywords: ترخیص کالا از گمرک; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid-β precursor protein; BBB; blood-brain barrier; BCI; brain clearance index; CAA; cerebral amyloid angiopathy; DEA; diethylamine; EVOO; extra-virgin olive oil; FA; formic acid; IDE; insulin degradi

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2015 سفارش ترجمه

Development and validation of a UHPLC diode array detector method for meropenem quantification in human plasma

Keywords: ترخیص کالا از گمرک; Meropenem; UHPLC; Pharmacokinetics; Therapeutic drug monitoring; Clearance;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Assessment of radioactive wastes from a DCLL fusion reactor: Disposal in El Cabril facility

Keywords: ترخیص کالا از گمرک; Fusion reactor; DCLL blanket; Clearance; Waste disposal; El Cabril

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Regular ArticleThe kidneys play an important role in the clearance of rFVIIa in rats

Keywords: ترخیص کالا از گمرک; AT; anti-thrombin; BSA; bovine serum albumin; C0; concentration at time 0 after iv administration; CL; clearance; CLNR; non-renal clearance; CLR; renal clearance; CMax; maximum concentration measured; EDTA; Ethylenediaminetetraacetic acid; ELISA; enzyme-l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Safe disassembly and storage of radioactive components of JT-60U torus

Keywords: ترخیص کالا از گمرک; Disassembly; JT-60U; Radioactivation; Fusion device; Clearance; JT-60SA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Non-clinical pharmacokinetics and pharmacodynamics of rVIII-SingleChain, a novel recombinant single-chain factor VIII

Keywords: ترخیص کالا از گمرک; AUC; area under the observed average plasma concentration vs. time curve; AUC0-last; AUC up to the last quantifiable sampling time; CI; confidence interval; CL; clearance; Cmax; maximum plasma concentration; ELISA; enzyme-linked immunosorbent assay; FL; f

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Significant association of poor glycemic control with increased resistance in efferent arterioles - Study of inulin and para-aminohippuric acid clearance in humans

Keywords: ترخیص کالا از گمرک; Inulin; Para-aminohippuric acid; Clearance; Type 2 diabetes; Efferent arteriole; Glomerular hemodynamic;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Vertical allometry: Fact or fiction?

Keywords: ترخیص کالا از گمرک; Vertical allometry; Allometric scaling; Clearance; Volume of distribution;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Uptake, localization and clearance of quantum dots in ciliated protozoa Tetrahymena thermophila

Keywords: ترخیص کالا از گمرک; Engineered nanoparticles; Uptake; Clearance; Phagocytosis; Endocytosis; Bioaccumulation; Fluorescence

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory activity of sesaminol and sesaminol triglycoside on cytochrome P450 enzymes and their pharmacokinetics in rats

Keywords: ترخیص کالا از گمرک; STG; sesaminol triglycoside; CYPs; cytochrome P450; Cmax; the maximum plasma concentration; Tmax; the time to reach maximum plasma concentration; t1/2; the half-lives; AUC; the area under the drug concentration-time curve; Cl; clearance; Vd; volume of d

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Target-mediated clearance and bio-distribution of a monoclonal antibody against the Kunitz-type protease inhibitor 2 domain of Tissue Factor Pathway Inhibitor

Keywords: ترخیص کالا از گمرک; AUC; area under the curve; Cl; clearance; DAB; 3,3′-diaminobenzidine; dIF; double immunofluorescence; EGFR; epidermal growth factor receptor; GAG; glycosaminoglycans; GPI; glycosylphosphatidylinositol; FVIII; Factor VIII; FIX; Factor IX; FXa; Factor Xa;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmaceutical nanotechnologyPEGylated cyclodextrins as novel siRNA nanosystems: Correlations between polyethylene glycol length and nanoparticle stability

Keywords: ترخیص کالا از گمرک; ANOVA; one-way analysis of variance; AUC; area under the curve; AUMC; area under the moment curve; BBB; blood-brain barrier; CL; clearance; CNS; central nervous system; CD; cyclodextrin; DIW; deionised water; DLS; dynamic light scattering; ELS; electropho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Antenatal Pharmacokinetics and Placental Transfer of N-Acetylcysteine in Chorioamnionitis for Fetal Neuroprotection

Keywords: ترخیص کالا از گمرک; C:M; Cord/maternal; CA; Chorioamnionitis; CL; Clearance; GA; Gestational age; GSH; Glutathione; IV; Intravenous; NAC; N-acetylcysteine; PK; Pharmacokinetic; t1/2; Terminal elimination half-life; Vd; Volume of distribution;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

In vitro hepatic microsomal metabolism of meloxicam in koalas (Phascolarctos cinereus), brushtail possums (Trichosurus vulpecula), ringtail possums (Pseudocheirus peregrinus), rats (Rattus norvegicus) and dogs (Canis lupus familiaris)

Keywords: ترخیص کالا از گمرک; Marsupials; Rat; Dog; Meloxicam; Microsome; Clearance; Metabolism

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Rapid clearance of Giardia lamblia DNA from the gut after successful treatment

Keywords: ترخیص کالا از گمرک; Clearance; follow-up; Giardia; real-time pcr; treatment;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Konservative Kalibrierung eines Freimesssystems für Reststoffe aus dem nuklearmedizinischen Betrieb

Keywords: ترخیص کالا از گمرک; Freigabe; radioaktive Reststoffe; Kalibrierung; Freigabemonitor; Clearance; radioactive waste; calibration; clearance monitor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Application of Polyglycerol Coating to Plasmid DNA Lipoplex for the Evasion of the Accelerated Blood Clearance Phenomenon in Nucleic Acid Delivery

Keywords: ترخیص کالا از گمرک; accelerated blood clearance (ABC) phenomenon; anti-PEG IgM; clearance; lipoplexes; non-viral gene delivery; PEGylation; plasmid DNA (pDNA); polyethylene glycol (PEG); polyglycerol (PG);

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه