Keywords: منطقه تعریف کننده تکمیلی; Deamidation; Liquid chromatography - mass spectrometry; Complementarity-determining region; Antigen;
مقالات ISI منطقه تعریف کننده تکمیلی (ترجمه نشده)
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Keywords: منطقه تعریف کننده تکمیلی; LCNEC; large cell neuroendocrine lung carcinoma; TCR; T-cell receptor; CDR; complementarity-determining region; HD; Hamming distance; OS; overall survival; Vβ; variable region of the T-cell receptor beta-chain; Large cell neuroendocrine lung carcinoma; T
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; Fab; fragment antigen-binding; Fc; fragment crystallizable; FR; framework region; Fv; fragment variable; RMSD; root-mean-square deviation; Antibody conformational changes; Complementarity determining regions; Compu
Keywords: منطقه تعریف کننده تکمیلی; HA; hemagglutinin; NA; neuraminidase; RBS; receptor-binding site; CDR; complementarity-determining region; bnAbs; broadly neutralizing antibodies; Fab; fragment antigen binding; influenza A virus; hemagglutinin; protein structure; evolution; antibody;
Keywords: منطقه تعریف کننده تکمیلی; APR; aggregation-prone region; FR; framework region; CDR; complementarity-determining region; RALS; right angle light scattering; FDA; US Food and Drug Administration; PDB; Protein Data Bank; MASS; mutant aggregation and stability spectrum; SEC; size-excl
Keywords: منطقه تعریف کننده تکمیلی; Chronic rhinosinusitis with nasal polyps; aspirin-exacerbated respiratory disease; Staphylococcus aureus enterotoxin; superantigen; superantibody; basophil; 7-AAD; 7-Aminoactinomycin D; AERD; Aspirin-exacerbated respiratory disease; CDR; Complementarity-d
Keywords: منطقه تعریف کننده تکمیلی; CBS; cystathionine-beta-synthase; CBSD; cystathionine-beta-synthase domain pair; S2P; site-2 protease; Nb; nanobody; CDR; complementarity-determining region; SEC-MALS; size exclusion chromatography with multiangle light scattering; Site-2 protease; CBS do
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; DEE; dead-end elimination; EC50; half maximal effective concentration; ELISA; enzyme-linked immunosorbent assay; FDPB; finite-difference Poisson-Boltzmann; FACS; fluorescence-activated cell sorting; FW4; “frame
Keywords: منطقه تعریف کننده تکمیلی; ANK; ankyrin repeat; CDR; complementarity-determining region; DAPI; 4â²,6â²-diamidino-2 phenyleindole; EGFP; enhanced green fluorescent protein; FLIM; fluorescence lifetime imaging microscopy; FRET; Förster resonant energy transfer; GK; gankyrin; GST;
Protein de novo sequencing by top-down and middle-down MS/MS: Limitations imposed by mass measurement accuracy and gaps in sequence coverage
Keywords: منطقه تعریف کننده تکمیلی; Fourier transform; Ion cyclotron resonance; ICR; FT-ICR; FTMS; Mass accuracy; Antibody; mAb; Complementarity-determining region; CDR; Framework region; FR;
Immunoglobulin heavy chain variable region analysis in dairy goats
Keywords: منطقه تعریف کننده تکمیلی; Ig; immunoglobulin; VH; immunoglobulin heavy chain variable region variable gene; DH; immunoglobulin heavy chain variable region diversity gene; JH; immunoglobulin heavy chain variable region joining gene; V(D)J; junction of immunoglobulin heavy chain var
Construction of humanized anti-HER2 single-chain variable fragments (husFvs) and achievement of potent tumor suppression with the reconstituted husFv-Fdt-tBid immunoapoptotin
Keywords: منطقه تعریف کننده تکمیلی; HER2; Immunogenicity; Humanized scFv; Immunoapoptotin; Targeted cancer therapy; Apoptosis; HER2; human epidermal growth factor receptor 2; scFv; single-chain variable fragment; husFv; humanized e23sFv; VL; light chain variable region; VH; heavy chain vari
A disulfide-stabilized human VL single-domain antibody library is a source of soluble and highly thermostable binders
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; FR; framework region; sdAb; single-domain antibody; VL; variable light chain immunoglobulin domain; Tm; melting temperature; Single-domain antibody; Protein engineering; Human VL; Phage display; Disulfide bond; The
Databases/Web ServersabYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; PDB; Protein Data Bank; IMGT; Immunogenetics Database; EMBL-ENA; European Molecular Biology Laboratory European Nucleotide Archive; antibodies; bioinformatics and computational biology; databases; sequence analysis
In vitro selection of bispecific diabody fragments using covalent bicistronic DNA display
Keywords: منطقه تعریف کننده تکمیلی; Bispecific antibody; Cell-free protein synthesis; Display technology; Disulfide stabilization; PURE system; bsAb; bispecific antibody; scFv; single-chain Fv; taFv; tandem scFv; dsDb; disulfide-stabilized diabody; CDR; complementarity-determining region; F
Production of a soluble single-chain variable fragment antibody against okadaic acid and exploration of its specific binding
Keywords: منطقه تعریف کننده تکمیلی; Okadaic acid; CLEIA; Single-chain variable fragment; Binding complex; OA; okadaic acid; DSP; diarrhetic shellfish poisoning; ELISA; enzyme-linked immunosorbent assay; scFv; single-chain variable fragment; CDR; complementarity-determining region; PDB; Prot
Nicotiana benthamiana cathepsin B displays distinct enzymatic features which differ from its human relative and aleurain-like protease
Keywords: منطقه تعریف کننده تکمیلی; Antibody; Cathepsin; Cysteine protease; Expression platform; Plant; Proteolysis; Abz; 2-aminobenzoyl; ALP; aleurain-like protease; CathB; cathepsin B; CHN2; diazomethyl; CDR; complementarity-determining region; DTT; dithiothreitol; Endo H; endoglucosamini
CDR3β sequence motifs regulate autoreactivity of human invariant NKT cell receptors
Keywords: منطقه تعریف کننده تکمیلی; iNKT; Autoreactivity; TCR; CDR3β; aAPC; artificial antigen-presenting cells; α-GalCer; α-galactosylceramide; β-GlcCer; β-glucopyranosylceramide; CDR; complementarity-determining region; eLPA; C16-alkanyl-lysophosphatidic acid; iNKT; invariant natural
Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; ncRNA; non-coding RNA; ssRNA; single-stranded RNA; Deoxy R; deoxynucleotide version of the R strand; MR; molecular replacement; PBS; phosphate-buffered saline; R.T.; room temperature; Phage display; RNA-binding Fab
The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity
Keywords: منطقه تعریف کننده تکمیلی; Cathepsin; Cysteine protease; Cell death; Degradomics; Plant; ALP; aleurain-like protease; Bz; benzoyl; CHN2; diazomethyl; CDR; complementarity-determining region; DTT; dithiothreitol; mAb; monoclonal antibody; MCA; 4-methylcoumaryl-7-amide; Nb; Nicotiana
Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects
Keywords: منطقه تعریف کننده تکمیلی; Immunotherapy; antigen-specific B cells; peanut allergy; food allergy; antibody repertoire; APC; Allophycocyanin; BCR; B-cell receptor; CDR; Complementarity-determining region; NGS; Next-generation sequencing; OIT; Oral immunotherapy; PNOIT; Peanut oral i
Immune deficiencies, infection, and systemic immune disordersDefective B-cell memory in patients with Down syndrome
Keywords: منطقه تعریف کننده تکمیلی; Down syndrome; common variable immunodeficiency; antibody; B cell; selection; somatic hypermutation; IgM; IgA; plasma cell; AID; Activation-induced cytidine deaminase; BAFF; B cell-activating factor; CDR; Complementarity-determining region; CVID; Common
A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency
Keywords: منطقه تعریف کننده تکمیلی; Recombination-activating gene 1; V(D)J recombination; severe combined immune deficiency; Omenn syndrome; autoimmunity; genotype-phenotype correlation; immune repertoire; A-MuLV; Abelson murine leukemia virus; CDR; Complementarity-determining region; CID-G
Structural and functional characterization of the single-chain Fv fragment from a unique HCV E1E2-specific monoclonal antibody
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; DAAs; direct-acting antivirals; ELISA; enzyme-linked immunoabsorbent assay; FR; framework region; GT; genotype; HCV; hepatitis C virus; HCVsp; serum-derived HCV particles; HRP; horseradish peroxidase; IgG; immunogl
Determination of allergen specificity by heavy chains in grass pollen allergen-specific IgE antibodies
Keywords: منطقه تعریف کننده تکمیلی; Allergy; allergen; IgE antibodies; specificity; affinity; CDR; Complementarity-determining region; RU; Resonance units; ScFv; Single chain variable fragment; VH; Heavy chain variable region; VL; Light chain variable region;
A novel high-sensitivity electrochemiluminescence (ECL) sandwich immunoassay for the specific quantitative measurement of plasma glucagon
Keywords: منطقه تعریف کننده تکمیلی; ECL; electrochemiluminescence; RIA; radioimmunoassay; GLP; glucagon like peptide; TBST; Tris buffered saline with 0.05% Tween-20; BSA; bovine serum albumin; PBS; phosphate buffered saline; WT; wild-type; MRD; minimum required dilution; scFv; single chain
Allergen specificity of IgG4-expressing B cells in patients with grass pollen allergy undergoing immunotherapy
Keywords: منطقه تعریف کننده تکمیلی; Immunotherapy; IgG4; Phl p 7; blocking antibody; CDR; Complementarity-determining region; FWR; Framework region; HBS; HEPES-buffered saline; ISU; ISAC standardized units; SPR; Surface plasmon resonance;
HIC resolution of an IgG1 with an oxidized Trp in a complementarity determining region
Keywords: منطقه تعریف کننده تکمیلی; IgG1; Tryptophan; Complementarity-determining region; Oxidation; Hydrophobic interaction chromatography; Mass spectrometry
Systematic mutation and thermodynamic analysis of central tyrosine pairs in polyspecific NKG2D receptor interactions
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; HEL; hen egg white lysozyme; SPR; surface plasmon resonance; ITC; isothermal titration calorimetry; Natural killer cell receptors; Mutagenesis; Polyspecific protein-protein interactions; Killer lectin-like recept
A common idiotype in IgE and its relation to recognition of the grass pollen allergen Phl p 2
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; scFv; single chain antibody fragment variable; VH; heavy chain variable domain; Allergy; Antibody repertoire development; IgE; Phl p 2;
Selection, design, and engineering of therapeutic antibodies
Keywords: منطقه تعریف کننده تکمیلی; Antibody engineering; target selection; biologic therapeutics; ADCC; Antibody-dependent cellular cytotoxicity; CDR; Complementarity-determining region; FcγR; IgG Fc γ receptor; HER-2; Human epidermal growth factor receptor 2;
Biased use of VH5 IgE-positive B cells in the nasal mucosa in allergic rhinitis
Keywords: منطقه تعریف کننده تکمیلی; Human; allergic rhinitis; VH5; superantigen; B lymphocyte; mucosa; CDR; Complementarity-determining region; FWR; Framework region; R/S; Replacement/silent mutation ratio;
Identification of novel VH1/J558 immunoglobulin germline genes of C57BL/6 (Ighb) allotype
Keywords: منطقه تعریف کننده تکمیلی; Ab; antibody; ANA; antinuclear antibody; B6; C57BL/6 inbred strain; CDR; complementarity-determining region; HC; heavy chain; Ig; immunoglobulin; LC; light chain; pI; isoelectric point; C57BL/6; J558; Antibodies; Anti-DNA; Repertoire;
Clonal expansion of IgA-positive plasma cells and axon-reactive antibodies in MS lesions
Keywords: منطقه تعریف کننده تکمیلی; IgA; Immunoglobulin A; MS; Multiple sclerosis; VH; Variable heavy chain; CDR; Complementarity-determining region; FR; Framework; Ig; Immunoglobulin; CNS; Central nervous system; CSF; Cerebrospinal fluid; NF; Neurofilament; MALT; Mucosal-associated lymphoi
Affinity maturation of a VHH by mutational hotspot randomization
Keywords: منطقه تعریف کننده تکمیلی; CDR; complementarity-determining region; Fab; antigen-binding fragment; FR; framework region; KD; dissociation constant; PBS; phosphate-buffered saline; PCR; polymerase chain reaction; PTH; parathyroid hormone; RIA; radioimmunoassay; scFv; single-chain va
Biochemical and structural impact of natural polymorphism in the HLA-A3 superfamily
Keywords: منطقه تعریف کننده تکمیلی; β2m; β2-microglobulin; CDR; complementarity-determining region; ER; endoplasmic reticulum; RT; reverse transcriptase; Tm; midpoint temperature; P; position; PCR; polymerase chain reaction; CTL; cytotoxic T lymphocyte; TAP; transporter associated with an